For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SFVLVSPSQLMAAAADVAGIGSAISAANAAALAPTSVLAAAGADEVSAAVAALFSAHAGQYQQLGARAAL FHEQFVQALTGAASAYASAEATNVEQQVLGLINAPTQALLGRPLIGNGADGTAANPNGGAGGLLYGNGGN GFSQTTAGLTGGTGGSAGLIGNGGNGGAGGAGANGGAGGNGGWLYGSGGNGGAGGAGPAGAIGAPGVAGG AGGAGGTAGLFGNGGVGGVGGDGGQGGNGAGAGASGTKGGDAGAGGAGGAGGWIHGHGGAGGDGGAGGAG GQASPGAPGPPSQPGGAGGAGGAGGRGGDGGSAGWLSGNGGDAGNGGGGGTAGGAGNGGQFGGDGGTGGT GGTAGAGGNGGRGAVLFGHGGNAGHGGAGGNGAAAGAGGEHVVATAGKGGTGGVGGDGGGGGAGGGGGLL YGNGGAGGAGNSGGDGGTGLNAALGGNGGGGGVGGNAGAGGTGGSAGWLSGNGGAGGSGGSAGAGGAGGK GGDTPNGLAINPGIGGNGGDTGNAGNGGNGGSAARLFGGGGAGGAGGTGSTAGSGGSGGTNPPTGLQAAG GNGGSGHAGGHGGNGGGAGLLGGGGTGGNGGGGGQGGLGAAAGGVDGNGGNGGNGGKGGDAQLVGDGGNG GNGGKGGAGLIAGLDGAGGAGGTRGLIFGNAGTPGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1067c | PE_PGRS19 | - | 100% (667) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 0.0 | 53.22% (729) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv1087 | PE_PGRS21 | 0.0 | 51.08% (785) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1096c | PE_PGRS19 | 0.0 | 98.51% (673) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-137 | 48.99% (592) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 2e-12 | 39.13% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 4e-50 | 34.76% (443) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_5321 | - | 0.0 | 51.98% (731) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 1e-23 | 40.86% (186) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-119 | 42.52% (675) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-43 | 39.16% (286) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 1e-176 | 48.82% (762) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-136 | 46.71% (608) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1067c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1096c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5321|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv1067c|M.tuberculosis_H37Rv ------------------MSFVLVSPSQLMAAAADVAGIGSAISAANAAA
Mb1096c|M.bovis_AF2122/97 ------------------MSFVLVSPSQLMAAAADVAGIGSAISAANAAA
MMAR_5321|M.marinum_M ------------------MSYLLVTPELLTSAATDLEGIASALSTANLAA
MUL_4367|M.ulcerans_Agy99 ------------------MSFVSVGPGLLEAAARDLAGLGAGLREANLAA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAID
Rv1067c|M.tuberculosis_H37Rv LAP--------------------------------TSVLAAAGADEVSAA
Mb1096c|M.bovis_AF2122/97 LAP--------------------------------TSVLAAAGADEVSAA
MMAR_5321|M.marinum_M AVP--------------------------------TTGVLAAGADEVSAA
MUL_4367|M.ulcerans_Agy99 AGA--------------------------------TVGVLPAAGDEVSAA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VSAAQVG------------------------------AVMPVVAESVASN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VTG-------------------------------ADDAATASAPDRVISA
Rv1067c|M.tuberculosis_H37Rv VAALFSAHAG-----------QYQQLGARAALFHEQFVQALTGAASAYAS
Mb1096c|M.bovis_AF2122/97 VAALFSAHAG-----------QYQQLGARAALFHEQFVQALTGAASAYAS
MMAR_5321|M.marinum_M VASLFAGYGQ-----------AYQSISLQANAFQAQFIQAINGAGGAYAA
MUL_4367|M.ulcerans_Agy99 IAELFGGFGR-----------EYQAMGARVALLHDDFVRALTAGGSAYGQ
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 YGYQSQWVNTG---------NPIHDLSGNLQNYYAAQPDGPSILSPSLLS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ILGTREG-------------------AADAGLQLSSIGVTWTDQLEAAAL
Rv1067c|M.tuberculosis_H37Rv AEATN------VEQQVLG-LINAPTQALLG--------RPLIGNGADGTA
Mb1096c|M.bovis_AF2122/97 AEATN------VEQQVLG-LINAPTQALWG--------RPLIGNGADGTA
MMAR_5321|M.marinum_M AEAASTSPLQAFEDTVLG-VINAPTQTLLG--------RPLIGDGAAGTA
MUL_4367|M.ulcerans_Agy99 AEALNMWPLQELEQQALG-VVNAPSMALFG--------RPSIGNGVDGVA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 PRDNDFLSHNDTDFASHNPIASGNQVMSPS------------GNVDSFNR
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 RDALAARRIDNVMLVSAFLAAAALAQNVGG----------AMGYERTAVL
Rv1067c|M.tuberculosis_H37Rv AN-PNGGAGGLLYGNGGNGFSQTTAGLTGGTGGSAG--LIG-NGGNGGAG
Mb1096c|M.bovis_AF2122/97 AN-PNGGAGGLLYGNGGNGFSQTTAGLTGGTGGSAG--LIG-NGGNGGAG
MMAR_5321|M.marinum_M AN-PNGGAGGFLYGNGGNGFSQTTAGVAGGSGGAAG--LIG-NGGMGGAG
MUL_4367|M.ulcerans_Agy99 GTGQAGGAGGILWGNGGNG-GLGAAGANGGAGGSAG--LIG-TGGVGGAG
Mflv_5091|M.gilvum_PYR-GCK QN------GGILFGNGGSGWNSDVVGMDGGNGGNGG--LFGGNGGNGGNG
Mvan_1264|M.vanbaalenii_PYR-1 QN------GGILFGNGGSGWNSEIAGVSGGNGGNAG--LFGGNGGNGGNG
MSMEG_0868|M.smegmatis_MC2_155 DN-PNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAG--LFG-NGGNGGVG
TH_3810|M.thermoresistible__bu -----------VDGDGGSG---------GRTGLFSK--LSR--GGDGGDG
MAB_4284c|M.abscessus_ATCC_199 GPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPI--ASG-QGSTAVNG
MLBr_01183|M.leprae_Br4923 --------MPLFLNAEPQALTAAANTLEGLSAATVA--SNA--AAAQLTT
MAV_4827|M.avium_104 LVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLE
. ..
Rv1067c|M.tuberculosis_H37Rv GAGAN------GGAGGNGG--WLYGSGGNGGAGGAG--------------
Mb1096c|M.bovis_AF2122/97 GAGAN------GGAGGNGG--WLYGSGGNGGAGGAG--------------
MMAR_5321|M.marinum_M GAGAA------GGAGGTGG--WWFGNGGVGGAGGAG--------------
MUL_4367|M.ulcerans_Agy99 GVGAAGMTGGSGGAGGGGG--WLWGAGGSGGAAGAGGSGGSGGWLWGNAG
Mflv_5091|M.gilvum_PYR-GCK LGGGN------GGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG-----
Mvan_1264|M.vanbaalenii_PYR-1 LGSGD------GGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG-----
MSMEG_0868|M.smegmatis_MC2_155 WAGLD------GGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGG---
TH_3810|M.thermoresistible__bu GLGGN------GGHGGGTGIISLLSLAGNGGNGGNG--------------
MAB_4284c|M.abscessus_ATCC_199 DVRDSNIIN--ADHGSNVGVDQSQTRVGGDYTNVSG--------------
MLBr_01183|M.leprae_Br4923 EIAPP------AADDVSILLAHFFSGHGRQYQAHAS--------------
MAV_4827|M.avium_104 SLPGG-----LLLVGSGVDVAPLKQVLQTTTFLDVS--------------
. .
Rv1067c|M.tuberculosis_H37Rv ------------------------------PAGAIGAPGVAGGAGGAGG-
Mb1096c|M.bovis_AF2122/97 ------------------------------PAGAIGAPGVAGGAGGAGG-
MMAR_5321|M.marinum_M ------------------------------TAGAVGFNGVSGGAGGAGG-
MUL_4367|M.ulcerans_Agy99 QTAGAGVGGAGGAGGAGDAGDQGVSGVAPGEAGAVGFAGGAGGAGGAGGN
Mflv_5091|M.gilvum_PYR-GCK ---------------------------APGVAGATGATGVTSGVVGGNGE
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------APGVAGATGATGVTSNVTGGNGA
MSMEG_0868|M.smegmatis_MC2_155 ---------------------------TGGTGGTGGGTGGTGGIGGTGGG
TH_3810|M.thermoresistible__bu -------------------------------YRTTDNNALDGGHGGNGG-
MAB_4284c|M.abscessus_ATCC_199 ----------------------------HGSADIDKSVTVVDDHSQRNTT
MLBr_01183|M.leprae_Br4923 -------------------------------QGATNHQDLIQSLLTSSS-
MAV_4827|M.avium_104 -------------------------------VAEEPETALARGAALAAAN
.
Rv1067c|M.tuberculosis_H37Rv ------TAGLFGNGGVGGVGGDGGQ------------------GGNGAGA
Mb1096c|M.bovis_AF2122/97 ------TAGLFGNGGVGGVGGDGGQ------------------GGNGAGA
MMAR_5321|M.marinum_M ------AAGWWGAGGAGGQGGTGGM------------------AGGYDNV
MUL_4367|M.ulcerans_Agy99 GVGGG-VNGAGGAGGAGGVGGGGGAGASGVGAGVAGGDGGTGGAGGAAGV
Mflv_5091|M.gilvum_PYR-GCK DAVGYGATGAAGAAGAAGAAGAAG----------------AVGSAGAAGE
Mvan_1264|M.vanbaalenii_PYR-1 DAVGYGATGAAGAAGAAGAAGKAG----------------AVGSAGTAGS
MSMEG_0868|M.smegmatis_MC2_155 LFGLLGHSGSTGAAGAAGNGGDGGNG--GFGYVLIAGPNVTVGSETRGGT
TH_3810|M.thermoresistible__bu ------NVGFFSLFNLGGAGGWGGS--------------------GVDGV
MAB_4284c|M.abscessus_ATCC_199 NINDSFNTDRSTNIGSGNTTNTEIG------------------SHNQANI
MLBr_01183|M.leprae_Br4923 -----------AYAGTETANHDSL--------------------------
MAV_4827|M.avium_104 APLFASSTAALAYAQDPGTGAVDQYS---------------LPDYLYVPV
Rv1067c|M.tuberculosis_H37Rv G-ASGTK-----------GGDAGAGGAGGAG------------------G
Mb1096c|M.bovis_AF2122/97 G-ASGTK-----------GGDAGAGGAGGAG------------------G
MMAR_5321|M.marinum_M NSVYGTT-----------AGNGGDGGAGGRG------------------G
MUL_4367|M.ulcerans_Agy99 GGAAGTGGTGGAAGVAGTGGDGGDGGAGGAGSDASLAG---------QAG
Mflv_5091|M.gilvum_PYR-GCK AGETGTWG--------NAGLPGKAGDAGGAG----------------AVG
Mvan_1264|M.vanbaalenii_PYR-1 AGAPGVWG--------NAGLPGAAGAAGGAG----------------AIG
MSMEG_0868|M.smegmatis_MC2_155 GGAGGTGGQ------STAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIG
TH_3810|M.thermoresistible__bu DVVGGNP----------------DGG------------------------
MAB_4284c|M.abscessus_ATCC_199 GTSTSAGG--------SAAVGGNAGLAGNAG-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 DPEPGD--------------------------------------------
Rv1067c|M.tuberculosis_H37Rv WIHGHG------GAGGDGGAGGAG-----------------GQASPGAPG
Mb1096c|M.bovis_AF2122/97 WIHGHG------GAGGDGGAGGAG-----------------GQASPGAPG
MMAR_5321|M.marinum_M WLFGDA------GAGGQGGLGGDG-----------------NYAGQGSYG
MUL_4367|M.ulcerans_Agy99 FAGGSG------GAGGVGGSAGAG-----------------GVNGSGGDG
Mflv_5091|M.gilvum_PYR-GCK AAGAAG------TVGTAGATGGTG---------------TGANGGAGGVG
Mvan_1264|M.vanbaalenii_PYR-1 TAGVAG------AAGTAGATGGTG---------------VGGNGGAGQAG
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHSTGT
TH_3810|M.thermoresistible__bu ------------TPGAHGESHTPG-----------------VYTDRQGED
MAB_4284c|M.abscessus_ATCC_199 LAGNAG------LAGNAGLAGNAG-----------------LAGNAGLAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------DELAYSAVGEED-----------------AESPTVVIE
Rv1067c|M.tuberculosis_H37Rv PPSQPGGAG-----------------GAGGAGGRGGDGGSAG--------
Mb1096c|M.bovis_AF2122/97 PPSQPGGAG-----------------GAGGAGGRGGDGGSAG--------
MMAR_5321|M.marinum_M GVGGAGGAG-----------------GAAGMFGSGGSGGAGG--------
MUL_4367|M.ulcerans_Agy99 GAGAAGGAGGASA----------TVAGSGGVGGDGGAGGAAGGGVGAASL
Mflv_5091|M.gilvum_PYR-GCK GVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ----
Mvan_1264|M.vanbaalenii_PYR-1 GIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ----
MSMEG_0868|M.smegmatis_MC2_155 GIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIYS--
TH_3810|M.thermoresistible__bu GEDGTG----------------------TGIGGRGGNGGSSS--------
MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAG---------------LAGNAGLAGNAGLAGNAG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 KLFLPEDSE----------------PRRRPVLLVGSGLAVVG--------
Rv1067c|M.tuberculosis_H37Rv --WLSGNG-GDAGN------------------GGGGGTAGGA-------G
Mb1096c|M.bovis_AF2122/97 --WLSGNG-GDAGN------------------GGGGGTAGGA-------G
MMAR_5321|M.marinum_M --EGGAFGDGNAGG------------------SGSGGHGGNG-------G
MUL_4367|M.ulcerans_Agy99 GGDGGHAGAGGAGGEGLSGGFNTGAAGGIGGAGGAGGTGGDS-------G
Mflv_5091|M.gilvum_PYR-GCK GTAGGTGGVGGIGGAG--------------STGAVGGVGGKG----IQGG
Mvan_1264|M.vanbaalenii_PYR-1 GTEGGTGGVGGVGGVG--------------ATGGAGGVGGKG----IQGG
MSMEG_0868|M.smegmatis_MC2_155 GADGEATGISAGGDGG--------------SATGADSLGGRGGTSWVQAG
TH_3810|M.thermoresistible__bu ----GTHPMAEDGE-------------------HVKALDGRP--------
MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAG-----------------LAGNAGLAGNAG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --ISAVLALEIALAIG-------------IRTTGTVALQPTPN-------
Rv1067c|M.tuberculosis_H37Rv NG---------------GQFGGDGGTGGTGGT------------------
Mb1096c|M.bovis_AF2122/97 NG---------------GQFGGDGGTGGTGGT------------------
MMAR_5321|M.marinum_M NG---------------GWLYGDAGAGGQGGN------------------
MUL_4367|M.ulcerans_Agy99 GV---------------GGVNGDGGAGGGGGRGGDGGSSTST--------
Mflv_5091|M.gilvum_PYR-GCK QG-------------LQGGKGGDGGAGGKGGDADSMGS------------
Mvan_1264|M.vanbaalenii_PYR-1 QG-------------LQGGQGGDGGTGGTGGDATSMGE------------
MSMEG_0868|M.smegmatis_MC2_155 YGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAI
TH_3810|M.thermoresistible__bu --------------------GLDGGNGSHGGN------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------LAGNAGLAGNAGLAG----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------QHLIVPTEQAPAPPP--------------------
Rv1067c|M.tuberculosis_H37Rv -------AGAGGNGG-RGAVLFG----------------------HGGNA
Mb1096c|M.bovis_AF2122/97 -------AGAGGNGG-RGAVLFG----------------------HGGNA
MMAR_5321|M.marinum_M -------AAPGAYSDNLGTIQYGN---------------------TSGNG
MUL_4367|M.ulcerans_Agy99 ----SGVGGAGGAGGNGGNAGFGVSAG-----------------GTGGSA
Mflv_5091|M.gilvum_PYR-GCK ------AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNG
Mvan_1264|M.vanbaalenii_PYR-1 ------AGATGGKGGNGGNGGRGSLFG---------------RGGNAGNG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNG
TH_3810|M.thermoresistible__bu ----------------------------------------------GGHG
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------NAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------------------------------------VQASA
Rv1067c|M.tuberculosis_H37Rv GH-------------------------GGAGG-------NGAAAGAGG--
Mb1096c|M.bovis_AF2122/97 GH-------------------------GGAGG-------NGAAAGAGG--
MMAR_5321|M.marinum_M GA-------------------------GGNGG-------VAGMIGTGG--
MUL_4367|M.ulcerans_Agy99 GD-------------------------GGAGGGAGGVDGVGGASGNGG--
Mflv_5091|M.gilvum_PYR-GCK AD----------------------GGTGGAGGAGGTGG-TGGAGGTGG--
Mvan_1264|M.vanbaalenii_PYR-1 GN----------------------GGTGGNGGNGGTGG-TGGNGGTGG--
MSMEG_0868|M.smegmatis_MC2_155 GNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGA
TH_3810|M.thermoresistible__bu GR--------------------------------------GGFLGIGG--
MAB_4284c|M.abscessus_ATCC_199 GN--------------------------------------AGLAGNAG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PQ--------------------------------------PKISVPEP--
Rv1067c|M.tuberculosis_H37Rv ---------------EHVVATAGKGGTGG--VGGDGGGGGAGGGGGL---
Mb1096c|M.bovis_AF2122/97 ---------------EHVMATAGKGGTGG--VGGDGGGG-AGGGGGL---
MMAR_5321|M.marinum_M ---------------AGGAGGAGGVNVYD--SGGGGGGGGTGGNGGW---
MUL_4367|M.ulcerans_Agy99 ---------------AAGAGGAGGSGIGAGIDGGAGGAGGTGGAAGFPGG
Mflv_5091|M.gilvum_PYR-GCK ---------------TGGTGGIGGAGSTGG-TGGTGGTGGTGGTGGTG--
Mvan_1264|M.vanbaalenii_PYR-1 ---------------TGGTGGIGGAGSTGG-TGGTGGTGGTGGTGGTG--
MSMEG_0868|M.smegmatis_MC2_155 SVWKANGQHSTGQTDTGGNGGRGGDGGTFV-NAGANGNGGAGGAGGVSE-
TH_3810|M.thermoresistible__bu -------------------------------SGGWGGHGGNGGDTDAD--
MAB_4284c|M.abscessus_ATCC_199 ---------------LAGNAGLAGNAAVAG-NAAVAGNAAVAGNAAVG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------VAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIP--
Rv1067c|M.tuberculosis_H37Rv -----LYGNGGAGG------AGNSGGD----GGTGLNAALGGNGGGGGVG
Mb1096c|M.bovis_AF2122/97 -----LYGNGGAGGNGGAGGAGNSGGD----GGTGLNAALGGNGGGGGVG
MMAR_5321|M.marinum_M -----LYGNAGSGGQGGAGGDGSFLWD----SPPNTNVYIGDAGGAGGVG
MUL_4367|M.ulcerans_Agy99 GGTTGAWGTGGAGGAGGAGGAGDHGGVGVNPGDSGTAGWAGGAGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK ----GTGGTGGTGGTGGKGGTGGTGGAG---GTG----GDGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGGTGGKGGTGGTGGDG---GTG----GTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 ----GEGGTGGHGGDGGRGGDGALGGNG---GTGGVGLGNGGKGGNGGNG
TH_3810|M.thermoresistible__bu ----------------------------------------GGNGGDGGNG
MAB_4284c|M.abscessus_ATCC_199 ----GVLNTGVSGAIGGSSHVGGAIN-----------ESLGGSGSVGGST
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------AAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQ
Rv1067c|M.tuberculosis_H37Rv GN------------AGAGGTGG---------SAGWLSGNGGAGGSGG---
Mb1096c|M.bovis_AF2122/97 GN------------AGAGGTGG---------SAGWLSGNGGAGGSGG---
MMAR_5321|M.marinum_M GHGGSAGLIGSGGAGGAGGVGG---------TGGYPAGNGGAGGDGGRAG
MUL_4367|M.ulcerans_Agy99 GSAAFNGVNGAGGAGGNGGAGGGGGAGASGIGAGVAGGDGGTGGTGGAAG
Mflv_5091|M.gilvum_PYR-GCK GTG---------GTGGTGGTGGAG------------DGTGGTGGTGG---
Mvan_1264|M.vanbaalenii_PYR-1 GTG---------GTGGTGGTGGAG------------DGLGGTGGTGG---
MSMEG_0868|M.smegmatis_MC2_155 GNGGTYVDPSHTGAGGNGGNGGAGRIRVNN-GTATGTATGGNGGNGGNGD
TH_3810|M.thermoresistible__bu GS------------AGRGGTGG---------------LRGVFGINGG---
MAB_4284c|M.abscessus_ATCC_199 AVG----------GGAHTGVGG-----------GVSTGVGVGSHVGGG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PVQPPVRVPQPPSPPQVGGTVPQS-----------PPQHQTPPGEGTP--
Rv1067c|M.tuberculosis_H37Rv ------------------SAGAGGAGGKGG------------------DT
Mb1096c|M.bovis_AF2122/97 ------------------SAGAGGAGGKGG------------------DT
MMAR_5321|M.marinum_M L--------------LFGSAGVGGQGGDGG------------------GN
MUL_4367|M.ulcerans_Agy99 TGGAAGTGGTGGAAGAAGSAGDGGAGGAGG------------------AG
Mflv_5091|M.gilvum_PYR-GCK ------------------TGGQGGQGGQGG-----------------TGG
Mvan_1264|M.vanbaalenii_PYR-1 ------------------TGGFGGQGGQGG-----------------TGG
MSMEG_0868|M.smegmatis_MC2_155 A-----------------DGHRGGKGGDGGEALIRATVIGSNASGTATGG
TH_3810|M.thermoresistible__bu -------------------NGRAGLGGRGX--------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------ISESLGGSGSVGG--------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------PKPDGPGNYGG--------------------
Rv1067c|M.tuberculosis_H37Rv PNG----LAINPGIGG----------------------NGGDTGNAGNGG
Mb1096c|M.bovis_AF2122/97 PNG----LAINPGIGG----------------------NGGDTGNAGNGG
MMAR_5321|M.marinum_M YIA----FTSNGNPNY----------------------NDGDAAGSGGAG
MUL_4367|M.ulcerans_Agy99 DDGSAGVVSGDPGTAG----------------------KAGGAGGAGGVG
Mflv_5091|M.gilvum_PYR-GCK TGGQGG-LGGGGGTG-----------------------GQGGTGGTGGQG
Mvan_1264|M.vanbaalenii_PYR-1 TGGQGG-LGGVGGTG-----------------------GTGGTGGTGGQG
MSMEG_0868|M.smegmatis_MC2_155 DGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHG
TH_3810|M.thermoresistible__bu ----------------------------------------------XXXG
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------STAVGGGAHTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------------------------------GHVPTPGAGG
Rv1067c|M.tuberculosis_H37Rv NGGSAARLFGGG--------GAGGAGGTGSTAGS----------------
Mb1096c|M.bovis_AF2122/97 NGGSAARLFGGG--------GAGGAGGTGSTAGS----------------
MMAR_5321|M.marinum_M GNGGAAGLFGAG--------AAGGAGGAGGLSGY----------------
MUL_4367|M.ulcerans_Agy99 GNGVAGGVNGSG--------GAGGAGGAGGTGGAGASGVPASVDGGDGGA
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTG--------GTGGAGGDGGLGGLG---------------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTG--------GTGGAGGDGGLGGLG---------------
MSMEG_0868|M.smegmatis_MC2_155 GNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLG---------------
TH_3810|M.thermoresistible__bu GGVGAAVRSGNG--------VFSGGGGTP---------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGVSTGVGVG--------SHVGGGISESLGGSG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 SGGSGGGHVPTP--------GAGGSGGSGGGHVP----------------
Rv1067c|M.tuberculosis_H37Rv -------------GGSGGTNPPTGLQAAGG-----------NGGSGHAGG
Mb1096c|M.bovis_AF2122/97 -------------GGSGGTNPPTGLQAAGG-----------NGGSGHAGG
MMAR_5321|M.marinum_M -------------RSAGNGGAGGAGGAGGV-----------LGGDGGAGG
MUL_4367|M.ulcerans_Agy99 GGAGGAAGTGGSGGSAGNTGAGGAGGAGGAGGSAASTGVNGDGGAGGAGG
Mflv_5091|M.gilvum_PYR-GCK -------------GFGGSGGTGGQGGLGGP-----------GGSTGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 -------------GFGGVGGTGGQGGQGGP-----------GGSTGGAGG
MSMEG_0868|M.smegmatis_MC2_155 -------------GNGGDGVVNTTANAANP-----------GSATGTATG
TH_3810|M.thermoresistible__bu --------------SAGFGVPTTIQFPAGS-------------CTSRAVS
MAB_4284c|M.abscessus_ATCC_199 -------------SVGGSTAVGGGAHTGVG------------GGVNTGVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------TPGTGGPGGTGGSGGG-----------HVPTPGAGT
Rv1067c|M.tuberculosis_H37Rv HGGNGG-GAGLLGGGGTGGNGGGGGQG-----GLGAAAGGVDGNGGNGGN
Mb1096c|M.bovis_AF2122/97 HGGNGG-GAGLLGGG-TGGNGGGGGQG-----GLGAAAGGVDGNGGNGGN
MMAR_5321|M.marinum_M DGGAAGNGVNDPVTGAVEGDGGIGGNG-----GTGGAALGWFGNGGAGGD
MUL_4367|M.ulcerans_Agy99 VGGLGGDSAATAGGGGAGGDGGKGGAGGAGVNGVGGGDGGKGGTGGAGGA
Mflv_5091|M.gilvum_PYR-GCK AGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQ
Mvan_1264|M.vanbaalenii_PYR-1 AGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQ
MSMEG_0868|M.smegmatis_MC2_155 GDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGV
TH_3810|M.thermoresistible__bu REG--------------------------------IMPSSRAASARAGAA
MAB_4284c|M.abscessus_ATCC_199 VGSHVGGGISESLGGSGSVGGSTAVGGG---AHTSAINDALGGSGSVGGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PGGSGGGHLPFPGAG-------------------STPGGSGGGHLPTPGA
Rv1067c|M.tuberculosis_H37Rv GGKG-----GDAQLVGD-GGNGGNGGKGGAG---LIAGLDG---------
Mb1096c|M.bovis_AF2122/97 GGKG-----GDAQLVGD-GGNGGNGGKGGAG---LIAGLDG---------
MMAR_5321|M.marinum_M GGAG-----GASQEFGDSGGNGGNGGAGGASG--ALIGAGG---------
MUL_4367|M.ulcerans_Agy99 GGAGSD---GIIPSNGGLGGNGGNGGNGGQAFGDGVGGAGG---------
Mflv_5091|M.gilvum_PYR-GCK GATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG---------
Mvan_1264|M.vanbaalenii_PYR-1 GATG------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG---------
MSMEG_0868|M.smegmatis_MC2_155 AGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIH
TH_3810|M.thermoresistible__bu CASS--------------TSRSRRSFCCSRA-------------------
MAB_4284c|M.abscessus_ATCC_199 TAVG--------GGAHTSAINESMNSSINASHSSSMNESFG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GTPG--------------GGLGGFGGGHAPAPGGGLGGGGG---------
Rv1067c|M.tuberculosis_H37Rv ---AGGAGG--TRGLIFGNAGTPGQ-------------------------
Mb1096c|M.bovis_AF2122/97 ---AGGAGG--TRGLIFGNAGTPGQ-------------------------
MMAR_5321|M.marinum_M ---VGGSGGGGGAGVVGPPAGNPGNDGLDGVTGASGLLFGG---------
MUL_4367|M.ulcerans_Agy99 ---IGGKGGNAAIGTIVINGGVGGAGGSGGLGGATEDGVGGVGCAGGAGG
Mflv_5091|M.gilvum_PYR-GCK --TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAG
Mvan_1264|M.vanbaalenii_PYR-1 --TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAG
MSMEG_0868|M.smegmatis_MC2_155 GAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----SSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----HAPAPGGGLGGFGGGHSGGGLGGLGGGHK-----------------
Rv1067c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1096c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5321|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 NGGRGDMLFTVGGSGGTGGDGGGGGSA--SGSGTGGSGGTGGVGGIGGDG
Mflv_5091|M.gilvum_PYR-GCK EDGDAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAG
Mvan_1264|M.vanbaalenii_PYR-1 DAGDPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDG
MSMEG_0868|M.smegmatis_MC2_155 NGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv1067c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1096c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5321|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 KLGGFGGDGGDGGDGGFGVIGGQGGGGGFGGLGGTG-AGGAPSDKGINGE
Mflv_5091|M.gilvum_PYR-GCK AE--------GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGA
Mvan_1264|M.vanbaalenii_PYR-1 SE--------GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGA
MSMEG_0868|M.smegmatis_MC2_155 SEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv1067c|M.tuberculosis_H37Rv ------
Mb1096c|M.bovis_AF2122/97 ------
MMAR_5321|M.marinum_M ------
MUL_4367|M.ulcerans_Agy99 PGNPG-
Mflv_5091|M.gilvum_PYR-GCK AGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 AGDSD-
MSMEG_0868|M.smegmatis_MC2_155 TGANNP
TH_3810|M.thermoresistible__bu ------
MAB_4284c|M.abscessus_ATCC_199 ------
MLBr_01183|M.leprae_Br4923 ------
MAV_4827|M.avium_104 ------