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M. ulcerans Agy99 MUL_4399 (-)

annotation: PE-PGRS family protein
coordinates: 4880207 - 4881649
length: 480

SYLLVAPELLTSAATDLEGIASALSTANLAAAVPTTGMLAAGADEVSAAVASLFAGYGQAYQSISLQANA
FQAQFIQAINGAGGAYVAAEAASTSPLQAFEDTVLGVINAPTQTLLGRPLIGDGAAGTVANPNGGAGGFL
YGNGGNGFSQTTAGVAGGAGGAAGLIGNGGMGGAGGAGAAGGAGGTGGWWFGNGGVGGAGGAGTAGAVGF
NGVSGGAGGAGGAAGWWGAGGAGGQGGTGGMAGGYDNVNGVFGITAGNGGDGGAGGRGGWLFGDAGAGGQ
GGLGGDGNYAGQGSYGGVGGAGGAGGAAGMFGSGGSGGAGGEGGAFGDGNAGGSGSGGHGGNGGNGGWLY
GDAGAGGQGGNAAPGAYSDNLGTFQSSYTSGNGGAGGNGGVAGMIGTGGAGGAGGAGGVNAFDSGGGGGG
GGNGGNGGAGGASGALIEAGGVGGSGGGGGAGVVGPPAGNPGNDGLDGVTGASGLLFGG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4399--100% (480)PE-PGRS family protein
M. ulcerans Agy99MUL_4400-e-15154.79% (511) PE-PGRS family protein
M. ulcerans Agy99MUL_3507-e-13749.91% (575) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1116PE_PGRS211e-14953.89% (553) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-8242.26% (478) triple helix repeat-containing collagen
M. tuberculosis H37RvRv1087PE_PGRS211e-14952.95% (559) PE-PGRS family protein
M. leprae Br4923MLBr_01183-5e-1135.42% (96) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-1e-4136.59% (369) hypothetical protein MAB_4284c
M. marinum MMMAR_5321-0.086.05% (516) PE-PGRS family protein
M. avium 104MAV_4827-6e-2142.26% (168) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-9e-7344.13% (392) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-7e-3636.75% (283) PUTATIVE -
M. vanbaalenii PYR-1Mvan_1264-2e-8142.50% (480) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5321|M.marinum_M               --------------------------------------------------
Mb1116|M.bovis_AF2122/97            --------------------------------------------------
Rv1087|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5321|M.marinum_M               --------------------------------------------------
Mb1116|M.bovis_AF2122/97            --------------------------------------------------
Rv1087|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5321|M.marinum_M               --------------------------------------------------
Mb1116|M.bovis_AF2122/97            --------------------------------------------------
Rv1087|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5321|M.marinum_M               --------------------------------------------------
Mb1116|M.bovis_AF2122/97            --------------------------------------------------
Rv1087|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_4399|M.ulcerans_Agy99           ------------------------------------MSYLLVAPELLTSA
MMAR_5321|M.marinum_M               ------------------------------------MSYLLVTPELLTSA
Mb1116|M.bovis_AF2122/97            ------------------------------------MSFVVVAPEVLAAA
Rv1087|M.tuberculosis_H37Rv         ------------------------------------MSFVVVAPEVLAAA
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104                ------------------------------------------MNIVLGVS
                                                                                      

MUL_4399|M.ulcerans_Agy99           ATDLEGIASALSTANLAAAVPTTGMLAAGADEVSAAVASLFAGYGQAYQS
MMAR_5321|M.marinum_M               ATDLEGIASALSTANLAAAVPTTGVLAAGADEVSAAVASLFAGYGQAYQS
Mb1116|M.bovis_AF2122/97            ASDLAGIGSTLAQANAAALAPTTAVLAAGADEVSAAIASLFGAHGQAYQA
Rv1087|M.tuberculosis_H37Rv         ASDLAGIGSTLAQANAAALAPTTAVLAAGADEVSAAIASLFGAHGQAYQA
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu      ------------------------------------------------VD
MLBr_01183|M.leprae_Br4923          -------MPLFLNAEPQALTAAANTLEG---LSAATVASNAAAAQLTTEI
MAB_4284c|M.abscessus_ATCC_199      VEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVN
MAV_4827|M.avium_104                MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
                                                                                      

MUL_4399|M.ulcerans_Agy99           ISLQANAFQAQFIQAINGAGGAYVAAEAASTSPLQAFEDTVLGVINAPTQ
MMAR_5321|M.marinum_M               ISLQANAFQAQFIQAINGAGGAYAAAEAASTSPLQAFEDTVLGVINAPTQ
Mb1116|M.bovis_AF2122/97            VSAQMSAFHAQFMQALTGAGGAYAAAEAVNVSAAQSVEQDLLAAINARFE
Rv1087|M.tuberculosis_H37Rv         VSAQMSAFHAQFMQALTGAGGAYAAAEAVNVSAAQSVEQDLLAAINARFE
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu      GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MLBr_01183|M.leprae_Br4923          APPAADDVSILLAHFFSGHGRQYQAHAS--------------QGATNHQD
MAB_4284c|M.abscessus_ATCC_199      TGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHN
MAV_4827|M.avium_104                REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
                                                                                      

MUL_4399|M.ulcerans_Agy99           TLLGRPLIGDGAAGTVANPNGGAGGFLYGNGGNGF---------------
MMAR_5321|M.marinum_M               TLLGRPLIGDGAAGTAANPNGGAGGFLYGNGGNGF---------------
Mb1116|M.bovis_AF2122/97            RIFGRPLIGDGANGGPGQ-DGGPGGLLYGNGGNGG---------------
Rv1087|M.tuberculosis_H37Rv         RIFGRPLIGDGANGGPGQ-DGGPGGLLYGNGGNGG---------------
Mflv_5091|M.gilvum_PYR-GCK          VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1       VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155      GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu      IIS--------------------LLSLAGNGGNGG---------------
MLBr_01183|M.leprae_Br4923          LIQS---------------------LLTSSSAYAG---------------
MAB_4284c|M.abscessus_ATCC_199      PIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGN---------------
MAV_4827|M.avium_104                LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGS---------------
                                                                     .                

MUL_4399|M.ulcerans_Agy99           -SQTTAGVAGGAGGAAG---------------------------------
MMAR_5321|M.marinum_M               -SQTTAGVAGGSGGAAG---------------------------------
Mb1116|M.bovis_AF2122/97            -TSTTVGMAGGNGGAAG---------------------------------
Rv1087|M.tuberculosis_H37Rv         -TSTTVGMAGGNGGAAG---------------------------------
Mflv_5091|M.gilvum_PYR-GCK          VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1       VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155      VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu      NGYRTTDNNALDGGHGG---------------------------------
MLBr_01183|M.leprae_Br4923          --TETANHDSL---------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --RDTTAIGDGAVAVGG---------------------------------
MAV_4827|M.avium_104                --IPDVYKQQIRAESYG---------------------------------
                                                                                      

MUL_4399|M.ulcerans_Agy99           ------------------------------------------LIGNGGMG
MMAR_5321|M.marinum_M               ------------------------------------------LIGNGGMG
Mb1116|M.bovis_AF2122/97            ------------------------------------------LIGNGGFG
Rv1087|M.tuberculosis_H37Rv         ------------------------------------------LIGNGGFG
Mflv_5091|M.gilvum_PYR-GCK          AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1       AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155      AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu      ------------------------------------------NGGNVGFF
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------------------------------SNSGP
MAV_4827|M.avium_104                --------------------------------------------DAAGQL
                                                                                      

MUL_4399|M.ulcerans_Agy99           GAGGAGAAGGAG----------------GTGGWWFGNGGVGGAGGAGTA-
MMAR_5321|M.marinum_M               GAGGAGAAGGAG----------------GTGGWWFGNGGVGGAGGAGTA-
Mb1116|M.bovis_AF2122/97            GGGGPGAAGGNG----------------GAGGWLFGNGGAGGAGGLGVAP
Rv1087|M.tuberculosis_H37Rv         GGGGPGAAGGNG----------------GAGGWLFGNGGAGGAGGLGVAP
Mflv_5091|M.gilvum_PYR-GCK          GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1       QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155      TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu      SLFNLGG--------------------AGGWGGSGVDG------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      IASGQGSTAVNG----------------DVRDSNIINADHGSNVGVDQSQ
MAV_4827|M.avium_104                SAMVAGLEKLES-----------------LPGGLLLVGSGVDVAPLKQVL
                                                                                      

MUL_4399|M.ulcerans_Agy99           ----------GAVGFNGVSGGAGGAGGAAG--------------------
MMAR_5321|M.marinum_M               ----------GAVGFNGVSGGAGGAGGAAG--------------------
Mb1116|M.bovis_AF2122/97            ----------GVPGGAGGAGGAGGVGGPAG--------------------
Rv1087|M.tuberculosis_H37Rv         ----------GVPGGAGGAGGAGGVGGPAG--------------------
Mflv_5091|M.gilvum_PYR-GCK          -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1       -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155      SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu      ---------VDVVGGNP---------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      TRVGGDYTNVSGHGSADIDKSVTVVDDHSQ--------------------
MAV_4827|M.avium_104                QTTTFLDVSVAEEPETALARGAALAAANAP--------------------
                                                                                      

MUL_4399|M.ulcerans_Agy99           ------WWGAGGAGGQG-----------------------------GTG-
MMAR_5321|M.marinum_M               ------WWGAGGAGGQG-----------------------------GTG-
Mb1116|M.bovis_AF2122/97            ------LWGHGGAGGAG-----------------------------GAGV
Rv1087|M.tuberculosis_H37Rv         ------LWGHGGAGGAG-----------------------------GAGV
Mflv_5091|M.gilvum_PYR-GCK          --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1       --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155      KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu      ---------DGGTPG------------------------------AHGES
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------RNTTNINDSFN----------------------------TDRST
MAV_4827|M.avium_104                -----LFASSTAALAYAQ----------------------------DPGT
                                                                                      

MUL_4399|M.ulcerans_Agy99           GMAGGYDNVNGVFGI-----------------------------------
MMAR_5321|M.marinum_M               GMAGGYDNVNSVYGT-----------------------------------
Mb1116|M.bovis_AF2122/97            AGAGGFEGTIGAGGAG----------------------------------
Rv1087|M.tuberculosis_H37Rv         AGAGGFEGTIGAGGAG----------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1       GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155      GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu      HTPGVYTDRQ----------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      NIGSGNTTNTEIGSHN----------------------------------
MAV_4827|M.avium_104                GAVDQYSLPDYLYVP-----------------------------------
                                                                                      

MUL_4399|M.ulcerans_Agy99           -------------TAGNGGDGGAGGRGGWLFGDAG---------------
MMAR_5321|M.marinum_M               -------------TAGNGGDGGAGGRGGWLFGDAG---------------
Mb1116|M.bovis_AF2122/97            ------------GVGGAGGVGGAGGAGGWLYGDAG---------------
Rv1087|M.tuberculosis_H37Rv         ------------GVGGAGGVGGAGGAGGWLYGDAG---------------
Mflv_5091|M.gilvum_PYR-GCK          -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155      AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu      ---------------GEDGEDGTGTGIGGRGGNGG---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------QANIGTSTSAGGSAAVGGNAG---------------
MAV_4827|M.avium_104                ----------------VDPEPGDDELAYSAVGEED---------------
                                                                                      

MUL_4399|M.ulcerans_Agy99           --AGGQGGLGGDG------NYAGQGSYGGVGGAG---GAGGAAGMFGSGG
MMAR_5321|M.marinum_M               --AGGQGGLGGDG------NYAGQGSYGGVGGAG---GAGGAAGMFGSGG
Mb1116|M.bovis_AF2122/97            --AGGDGGVGGAGGTGGLGNRGGAGGAGGAGGVG---GAGGAAGLWGGGG
Rv1087|M.tuberculosis_H37Rv         --AGGDGGVGGAGGTGGLGNRGGAGGAGGAGGVG---GAGGAAGLWGGGG
Mflv_5091|M.gilvum_PYR-GCK          --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155      TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE--GEGGTGGHGGDGG
TH_3810|M.thermoresistible__bu      -SSSGTHPMAEDG--------EHVKALDGRPGLD-----GGNGSHGGNGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG
MAV_4827|M.avium_104                ----AESPTVVIEKLFLPEDSEPRRRPVLLVGSG-----LAVVGISAVLA
                                                                                      

MUL_4399|M.ulcerans_Agy99           SGGAGGEGG----------------AFGDGNAGGSGSGGHGGNGGNGG--
MMAR_5321|M.marinum_M               SGGAGGEGG----------------AFGDGNAGGSGSGGHGGNGGNGG--
Mb1116|M.bovis_AF2122/97            AGGVGGTGGGAGLGAQSVTFSSSLSGLSGGDGGAGGAGGAGGAGGTGG--
Rv1087|M.tuberculosis_H37Rv         AGGVGGTGGGAGLGAQSVTFSSSLSGLSGGDGGAGGAGGAGGAGGTGG--
Mflv_5091|M.gilvum_PYR-GCK          KGGTGGTGG--------------AGGTG----GDGGTGGTGGTGGTG---
Mvan_1264|M.vanbaalenii_PYR-1       KGGTGGTGG--------------DGGTG----GTGGTGGTGGTGGTG---
MSMEG_0868|M.smegmatis_MC2_155      RGGDGALGG--------------NGGTGGVGLGNGGKGGNGGNGGNGGTY
TH_3810|M.thermoresistible__bu      HGGRGGFLG--------------IGGSG-------GWGGHGGNGGD----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      LAGNAGLAG------------------------NAGLAGNAGLAGNAG--
MAV_4827|M.avium_104                LEIALAIG--------------------------IRTTGTVALQPTPN--
                                                                                      

MUL_4399|M.ulcerans_Agy99           ---WLYGDAGAGGQGGNA------------APGAYSDNLG----TFQSSY
MMAR_5321|M.marinum_M               ---WLYGDAGAGGQGGNA------------APGAYSDNLG----TIQYGN
Mb1116|M.bovis_AF2122/97            ---WLYGGGGAAGSGGDG------------GTGGQGGAGG----AGVFSL
Rv1087|M.tuberculosis_H37Rv         ---WLYGGGGAAGSGGDG------------GTGGQGGAGG----AGVFSL
Mflv_5091|M.gilvum_PYR-GCK          ------GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGG
Mvan_1264|M.vanbaalenii_PYR-1       ------GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGFGG
MSMEG_0868|M.smegmatis_MC2_155      VDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGG
TH_3810|M.thermoresistible__bu      -------TDADGGNGGDG---------------GNGGSAG----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----LAGNAGLAGN--AG-------------LAGNAGLAG-------NAG
MAV_4827|M.avium_104                -------QHLIVPTEQAP------------APPPVQASAP----------
                                                                                      

MUL_4399|M.ulcerans_Agy99           TSGNGG-----------------AGGNGGVAGMIGTGGAG----------
MMAR_5321|M.marinum_M               TSGNGG-----------------AGGNGGVAGMIGTGGAG----------
Mb1116|M.bovis_AF2122/97            FGSGGG-----------------PGGNGGVGGVGGVGGAGGRAGLF----
Rv1087|M.tuberculosis_H37Rv         FGSGGG-----------------PGGNGGVGGVGGVGGAGGRAGLF----
Mflv_5091|M.gilvum_PYR-GCK          QGGQGG-----------------TGGTGGQGG-LGGGGGTG---------
Mvan_1264|M.vanbaalenii_PYR-1       QGGQGG-----------------TGGTGGQGG-LGGVGGTG---------
MSMEG_0868|M.smegmatis_MC2_155      KGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYN
TH_3810|M.thermoresistible__bu      -----------------------RGGTGGLRGVFGINGGNG---------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      LAGNAG-----------------LAGNAGLAGNAGLAGNAG---------
MAV_4827|M.avium_104                ------------------------QPKISVPEPVAAPKPLS---------
                                                                                      

MUL_4399|M.ulcerans_Agy99           --------------GAGGAGGVN--AFDSGGGGGGG--------------
MMAR_5321|M.marinum_M               --------------GAGGAGGVN--VYDSGGGGGGGGTGGNGGWLYGNAG
Mb1116|M.bovis_AF2122/97            --------------GVGGLGGAGGDAGDSGEGGFGGP--GLAGGLFGNPG
Rv1087|M.tuberculosis_H37Rv         --------------GVGGLGGAGGDAGDSGEGGFGGP--GLAGGLFGNPG
Mflv_5091|M.gilvum_PYR-GCK          --------------GQGGTGGTGGQGGTGGTGGTGGTG--------GTGG
Mvan_1264|M.vanbaalenii_PYR-1       --------------GTGGTGGTGGQGGTGGTGGTGGTG--------GTGG
MSMEG_0868|M.smegmatis_MC2_155      VVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGG
TH_3810|M.thermoresistible__bu      ---------------RAGLGGRGXXXXGGGVGAAVRSG------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------LAGNAAVAGNAAVAGNAAVAGNAAVG--------GVLN
MAV_4827|M.avium_104                ----------------PPVAAPLPAAPPPAAPPLPEAP----------PI
                                                                                      

MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5321|M.marinum_M               SGGQGGAGGDGSFLWDS-------PPNTNVYIGDAGGAGGVGGHGGSAGL
Mb1116|M.bovis_AF2122/97            NGGVGGIGGDAAAGGAG------GAGGNGGWLFGNGGAGGSGGDGGAAGR
Rv1087|M.tuberculosis_H37Rv         NGGVGGIGGDAAAGGAGGAGGNGGAGGNGGWLFGNGGAGGSGGDGGAAGR
Mflv_5091|M.gilvum_PYR-GCK          AGGDGGLGGLGGFGGSG----------------GTGGQGGLGGPGGSTGG
Mvan_1264|M.vanbaalenii_PYR-1       AGGDGGLGGLGGFGGVG----------------GTGGQGGQGGPGGSTGG
MSMEG_0868|M.smegmatis_MC2_155      NGGDGIDGGLGGNGGDG----------------VVNTTANAANPGSATGT
TH_3810|M.thermoresistible__bu      ---NGVFSGGGGTPSAG----------------FGVPTTIQFPAGSCTSR
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      TGVSGAIGGSSHVGGAIN-----------------ESLGGSGSVGGSTAV
MAV_4827|M.avium_104                PAAPPVVPVPVVVPPVP---------------VPVPVRIPVPDPVSPPQL
                                                                                      

MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5321|M.marinum_M               IGSGGAGGAGGVGGTGGYPAGNGGAGGDGGRAGLLFGSAGVGGQGGDGG-
Mb1116|M.bovis_AF2122/97            GGAGNLGSAGGINAPAGNPGSGSVGIGGAGGAGGTAGLFGDGGAGGAG--
Rv1087|M.tuberculosis_H37Rv         GGAGNLGSAGGINAPAGNPGSGSVGIGGAGGAGGTAGLFGDGGAGGAGGA
Mflv_5091|M.gilvum_PYR-GCK          AGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGAT
Mvan_1264|M.vanbaalenii_PYR-1       AGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGAT
MSMEG_0868|M.smegmatis_MC2_155      ATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASN
TH_3810|M.thermoresistible__bu      AVSREG------------------------IMPSSRAASARAG-------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGV
MAV_4827|M.avium_104                LAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTPPKP
                                                                                      

MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5321|M.marinum_M               GNYIAFTSNGNPNYNDGDAAGSGGAGGNGGAAGLFGAGAAGGAGGAGGLS
Mb1116|M.bovis_AF2122/97            -AAGGFGGISAATPSAGSEGAMGGAGGVGGNARLLGTGGAGGVGGGGGAG
Rv1087|M.tuberculosis_H37Rv         GAAGGFGGISAATPSAGSEGAMGGAGGVGGNARLLGTGGAGGVGGGGGAG
Mflv_5091|M.gilvum_PYR-GCK          GAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG------
Mvan_1264|M.vanbaalenii_PYR-1       GAQGATG------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG------
MSMEG_0868|M.smegmatis_MC2_155      GGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIA
TH_3810|M.thermoresistible__bu      --------------------AACASSTSRSRRSFCCSRA-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGG-----
MAV_4827|M.avium_104                DGPGNYG--------GGHVPTPGAGGSGGSGGGHVPTPGAGGSGG-----
                                                                                      

MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5321|M.marinum_M               GYRSAGNGGAGGAGGAGGVLGGDGGAGGDGGAAGNGVNDPVTGAVEGDGG
Mb1116|M.bovis_AF2122/97            GDGGRGGVATPGGQGGDAGDGGAGGAGGNGGGGASGAGGWLLG-TGGAGG
Rv1087|M.tuberculosis_H37Rv         GDGGRGGVATPGGQGGDAGDGGAGGAGGNGGG-ASGAGGWLLG-TGGAGG
Mflv_5091|M.gilvum_PYR-GCK          -----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------
Mvan_1264|M.vanbaalenii_PYR-1       -----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------
MSMEG_0868|M.smegmatis_MC2_155      AIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -VNTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTSAINDALGGSGS
MAV_4827|M.avium_104                ----SGGGHVPTPGTGGPGGTGGSGGGHVPTPGAGTPGGSGGGHLPFPGA
                                                                                      

MUL_4399|M.ulcerans_Agy99           --------------------------------------------GNGGNG
MMAR_5321|M.marinum_M               IGGNGGTGGAALGWFGNGGAGGDGGAGGA-------SQEFGDSGGNGGNG
Mb1116|M.bovis_AF2122/97            AGGNGGNGGKAGFSPGPTNFGLNGAGGG---------------GGVGGNG
Rv1087|M.tuberculosis_H37Rv         AGGNGGNGGKAGFSPGPTNFGLNGAGGG---------------GGVGGNG
Mflv_5091|M.gilvum_PYR-GCK          AAGEDGDAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKG
Mvan_1264|M.vanbaalenii_PYR-1       AAGDAGDPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155      VAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VGGSTAVGGGAHTSAINESMNSSIN-------------------------
MAV_4827|M.avium_104                GSTPGGSGGGHLPTPGAGTPGGGLGGFG----------------------
                                                                                      

MUL_4399|M.ulcerans_Agy99           GAG----------------------GASGALIEAGGVGGSGGGG---GAG
MMAR_5321|M.marinum_M               GAG----------------------GASGALIGAGGVGGSGGGG---GAG
Mb1116|M.bovis_AF2122/97            ATGPWLFGDGGAGGGGGAGGIGGDGGPTPGSTGAGAAGGHGGDAQLIGNG
Rv1087|M.tuberculosis_H37Rv         ATGPWLFGDG---------------GPTPGSTGAGAAGGHGGDAQLIGNG
Mflv_5091|M.gilvum_PYR-GCK          GAGAE----------------------GGAGGGGGAGGSGAGGAG--GAG
Mvan_1264|M.vanbaalenii_PYR-1       GDGSE----------------------GGAGGSGGAGGSGTGGAG--GAG
MSMEG_0868|M.smegmatis_MC2_155      GDGSEPGPGGN--------------GAGGAGGNGGTGGTTAGGSGNGGNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------ASHSSSMNESFGSSMGSHGAAGTG
MAV_4827|M.avium_104                ---------------------------GGHAPAPGGGLGGGGGHAPAPGG
                                                                                      

MUL_4399|M.ulcerans_Agy99           VVGPPAGNPGNDGLDGVTGASGLLFGG-----
MMAR_5321|M.marinum_M               VVGPPAGNPGNDGLDGVTGASGLLFGG-----
Mb1116|M.bovis_AF2122/97            GHGGAGGTGVPNGSGGAGGLSGLLFGEPGANG
Rv1087|M.tuberculosis_H37Rv         GHGGAGGTGVPNGSGGAGGLSGLLFGEPGANG
Mflv_5091|M.gilvum_PYR-GCK          GSGGSGGSGGSGGSGGAAGDSDD---------
Mvan_1264|M.vanbaalenii_PYR-1       GSGGSGGSGGAGGSGGAAGDSD----------
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGGADGTPGTAGTTGANNP---------
TH_3810|M.thermoresistible__bu      --------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------
MAB_4284c|M.abscessus_ATCC_199      FEAQGHAQGHASETAHTTLPGAEHH-------
MAV_4827|M.avium_104                GLGGFGGGHSGGGLGGLGGGHK----------