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M. tuberculosis H37Rv Rv1973 (-)

annotation: POSSIBLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN
coordinates: 2217164 - 2217646
length: 160

VSWSRVIAYGLLPGLALALTCGAGLLKWQDGAVRDAAVARAESVRAATDGTTALLSYRPDTVQHDLESAR
SRLTGTFLDAYTQLTHDVVIPGAQQKQISAVATVAAAASVSTSADRAVVLLFVNQTITVGKDAPTTAASS
VRVTLDNINGRWLISQFEPI
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1973--100% (160)POSSIBLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN
M. tuberculosis H37RvRv1362c-9e-2750.00% (128) hypothetical protein Rv1362c
M. tuberculosis H37RvRv3492c-1e-1225.32% (154) Mce associated protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1397c-3e-2649.22% (128) hypothetical protein Mb1397c
M. gilvum PYR-GCKMflv_2108-7e-5160.36% (169) hypothetical protein Mflv_2108
M. leprae Br4923MLBr_02598-3e-0725.95% (131) putative secreted protein
M. abscessus ATCC 19977MAB_4146c-5e-1022.60% (146) MCE-family protein
M. marinum MMMAR_2889-7e-5870.25% (158) Mce associated membrane protein
M. avium 104MAV_1970-1e-5060.00% (160) hypothetical protein MAV_1970
M. smegmatis MC2 155MSMEG_0353-3e-4557.69% (156) hypothetical protein MSMEG_0353
M. thermoresistible (build 8)TH_4601-5e-4958.49% (159) PUTATIVE putative hypothetical protein Mflv_2108
M. ulcerans Agy99MUL_2863-9e-5971.52% (158) Mce associated membrane protein
M. vanbaalenii PYR-1Mvan_4597-4e-4858.08% (167) hypothetical protein Mvan_4597

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2889|M.marinum_M               -----------------------------------------MTAVGPPGA
MUL_2863|M.ulcerans_Agy99           -----------------------------------------MTAVSRPGA
Rv1973|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_2108|M.gilvum_PYR-GCK          MTDDVKG---------DEANKSVDDKNDENK----VEAAPEAEAVESTEA
Mvan_4597|M.vanbaalenii_PYR-1       MSNEKTGTADITEDTTAAADEPATDTEQPAKGTDDAESAADKTGAEETDT
MAV_1970|M.avium_104                ---------------MSRLTWPKRSKSAPEDVALDANEVTEVSTTEAPGT
TH_4601|M.thermoresistible__bu      -----------------------------------VTATTGIEGSETTGP
MSMEG_0353|M.smegmatis_MC2_155      -----------------------------------------MLAAQEVSE
Mb1397c|M.bovis_AF2122/97           ------------------MTDDVRDVNTETTDATEVAEIDSAAGEAGDSA
MAB_4146c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02598|M.leprae_Br4923          -----------------------------------------MAAAEGGGS
                                                                                      

MMAR_2889|M.marinum_M               GECGDTDTAANGEPPAVVR---------------------------RRLR
MUL_2863|M.ulcerans_Agy99           GECGDTDTAGSGEPPAVVR---------------------------RRLR
Rv1973|M.tuberculosis_H37Rv         ------------------------------------------------MS
Mflv_2108|M.gilvum_PYR-GCK          VES-TEAVEPTGTDPEAT-----DADVTAAA-------------PTRRVE
Mvan_4597|M.vanbaalenii_PYR-1       VDEDAEVTEDADEDAEVTEDDDEDAEVTEDAGEDAEATDDAAVTPKRDGK
MAV_1970|M.avium_104                DEAETETDTAADSTGDTTDETSAEPTEGTVGEDEP--------AAEWRVD
TH_4601|M.thermoresistible__bu      AEADT---VAGDTSGRS---------------------------------
MSMEG_0353|M.smegmatis_MC2_155      PEAAQPQSDSGPR------------------------------------R
Mb1397c|M.bovis_AF2122/97           TEAFDTDSATESTAQKGQR---------------------------HRDL
MAB_4146c|M.abscessus_ATCC_199      ------------------------------------------------MR
MLBr_02598|M.leprae_Br4923          WRN-------------------------------------------RRAG
                                                                                      

MMAR_2889|M.marinum_M               WWPAIGYGLLPALALLLAGGTG-------FAKWQDCAVRDAAQAR-----
MUL_2863|M.ulcerans_Agy99           WWPVIAYGLLPALALLLAGGTG-------FAKWQDCAVRDAAQAR-----
Rv1973|M.tuberculosis_H37Rv         WSRVIAYGLLPGLALALTCGAG-------LLKWQDGAVRDAAVAR-----
Mflv_2108|M.gilvum_PYR-GCK          WSRVVAFLVLPALALVLAAGAG-------YLKWLDDSYRDGSMSVDGNGR
Mvan_4597|M.vanbaalenii_PYR-1       WARLTAFVLLPALALVLALGAG-------YLKWQDTTFRSGAIEASPSGR
MAV_1970|M.avium_104                WSRVVAFGVLPAIALLLAAAAG-------FFKWQDNSVRNTDIAR-----
TH_4601|M.thermoresistible__bu      WLRIVTHAVLPALIVVSALGAG-------YLKWMDGTADAVDRAR-----
MSMEG_0353|M.smegmatis_MC2_155      SVRVLAYVVIPLLIVGLAACAG-------YLQWRSSSMRAAQAAN-----
Mb1397c|M.bovis_AF2122/97           WRMQVTLKPVPVILILLMLISGGATGWLYLEQYRPDQQTDSGAAR-----
MAB_4146c|M.abscessus_ATCC_199      WLARIFVAVTVLVVVGLSAAAG-------GMYWHRVDTVASRAAG-----
MLBr_02598|M.leprae_Br4923          QRTAIAVVVAAVLFVGSAAFAG-------AAVQPYLADRATVAVK-----
                                                : :     :*                            

MMAR_2889|M.marinum_M               ----AESVQAATAGTIALLSYRPDTVRSDLDAARAKLTGAFLSDYTSLTR
MUL_2863|M.ulcerans_Agy99           ----AESVQAATAGTIALLSYRPDTVRSDLEAARAKLTGAFLSDYTSLTR
Rv1973|M.tuberculosis_H37Rv         ----AESVRAATDGTTALLSYRPDTVQHDLESARSRLTGTFLDAYTQLTH
Mflv_2108|M.gilvum_PYR-GCK          PSLAETSVQAARDSTIALLSYAPDTVEQQLGAARELLTGEFRDSYTSLTN
Mvan_4597|M.vanbaalenii_PYR-1       LSLAEKTVQIARDSTIALLSYKPDTVEQQLGAARDLLTGEFRDSYTSLTN
MAV_1970|M.avium_104                ----IESVQTAKDSTIAMLSYKPDTVEQQLRSARDLLTGEFRDSYTSLIT
TH_4601|M.thermoresistible__bu      ----VESVQAATDITIAMLSYQPDTVEEDLGAARDRMTGEFRDSYTSLTN
MSMEG_0353|M.smegmatis_MC2_155      ----VSAVPAATDSTIKMLSYKPDTVQKDLELAAEGLTGPFRDDYNSLIH
Mb1397c|M.bovis_AF2122/97           -----AAGAAASDGTIALLSYSPDTLDQDFATARSHLAGDFLSYYDQFTQ
MAB_4146c|M.abscessus_ATCC_199      ----ETLIKQAGKQIGSIFGYDYQTVERSLDEQYAGLTPEYRREFEDKAN
MLBr_02598|M.leprae_Br4923          ----LEVARTAANAITVLWTYTPENMDTLADRAATYVSGDFGAQYRKFVD
                                              *      :  *  :.:          ::  :   : .   

MMAR_2889|M.marinum_M               DVVIPGAKQKDISAVATVPAAASVSATGEHAIVLLFVNQTIIV-SQDA-P
MUL_2863|M.ulcerans_Agy99           DVVIPGAKQKDISAVATVPAAASVSATGEHAIVLLFVNQTIIV-SQDP-P
Rv1973|M.tuberculosis_H37Rv         DVVIPGAQQKQISAVATVAAAASVSTSADRAVVLLFVNQTITV-GKDA-P
Mflv_2108|M.gilvum_PYR-GCK          DVVIPGAKEKQIAAIATVPAAASVSVTADEAVVLLFVNQTVTV-GPDA-P
Mvan_4597|M.vanbaalenii_PYR-1       DVVIPGAKEKQISAVASVPAAASVSATPTEAVVLLFVNQTVSV-GADV-P
MAV_1970|M.avium_104                DVVIPGAKQQQISAEASIPAAASVSADPREAVVLVFVNQTTII-GKSA-P
TH_4601|M.thermoresistible__bu      DVVIPGAREKRISTVATVPAAASVQASTDHAVVVVFVNQATTV-GDDV-P
MSMEG_0353|M.smegmatis_MC2_155      DVVIPGAQEKQISAVATVPAAAVVSATGNRAVVMVFVNQTTIV-GADP-P
Mb1397c|M.bovis_AF2122/97           QIVAPAAKQKSLKTTAKVVRAAVSELHPDSAVVLVFVDQSTTS-KDSPNP
MAB_4146c|M.abscessus_ATCC_199      REIIPQAKQRKIVSQTSIVGTGIIAAHRDSAQVVVYMNRTITD-QSRT-P
MLBr_02598|M.leprae_Br4923          AIVGP-NKQAKITNSTEVTGVAVESLDASNAIAIVYTNTTSTSPLTKNIP
                                      : *  ::  :   : :  ..        * .::: : :         *

MMAR_2889|M.marinum_M               TSTASSVRVTLDKVDGRWLISRFDPV---------
MUL_2863|M.ulcerans_Agy99           TSTASSVRVTLDKVDGRWLISRFDPV---------
Rv1973|M.tuberculosis_H37Rv         TTAASSVRVTLDNINGRWLISQFEPI---------
Mflv_2108|M.gilvum_PYR-GCK          TDTASSVRVTLEKDGDRWLISKFDPV---------
Mvan_4597|M.vanbaalenii_PYR-1       TDTASSVRVTLEKVGDRWLISKFDPV---------
MAV_1970|M.avium_104                TDTASTVRVTLNKAGDRWLISKFEPV---------
TH_4601|M.thermoresistible__bu      TDTASTVRVTLEKVDDQWLMSGFEPI---------
MSMEG_0353|M.smegmatis_MC2_155      TSTASTVRVTMDKVGERWLVSDFTPI---------
Mb1397c|M.bovis_AF2122/97           SMAASSVMVTLAKVDGNWLITKFTPV---------
MAB_4146c|M.abscessus_ATCC_199      VYDSSSIQVDYTRAGDKWLISYITPL---------
MLBr_02598|M.leprae_Br4923          ALKYLSYRLFMKRSAVRWLVTRMTTITSLDLTPQL
                                         :  :   .   .**:: : .: