For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSYLVVVPELVAAAATDLANIGSSISAANAAAAAPTTALVAAGGDEVSAAIAALFGAHARAYQALSAQAA MFHEQFVRALAAGGNSYAVAEAATAQSVQQDLLNLINAPTQALLGRPLIGNGANGLPGTGQNGGDGGILY GNGGNGGSGGVNQAGGNGGNAGLWGNGGSGGAGGNATTAGRNGFNGGAGGSGGLLWGNGGAGGAGGNGGP APLVGGVGTTGGAGGNGGGAGLFYGFGGAGGNGGMGGVAPSTGPSMGILPAGGVGGPGGSGGASALAFGS GGVGGAGGLGGPTDGTVQGVGGFGGQGGNGGQSGLLFGNAGAGGAGAAGGAGTGDTESFGGHGGAGGDGG AVGLIGNGGAGGTGSPGAVVGGNGGVGGLGGAGSPGGLLYGTGGAGGNGGPGGDGGTGATVGFAGSGGFG GAGGIAQLFGTGGMGGSGGGIGAGTTTVVPPDVAPVGGTGGNGGRAGLLLGVGGMGGNGGATSVGGTLYA AGGNGGDGGLVWGNGGTGGSGGAGGAGSVGNGGAGGNAALLFGNGGAGGAGGAGGIGAGGAGGFGAVLFG NGGAGGSGAPGGIGAGGNGGNALLVGNGGNGGAGTGGAAGGAGGSGGLLFGQNGMPGP
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv1768 | PE_PGRS31 | - | 100% (618) | PE-PGRS FAMILY PROTEIN |
M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | e-176 | 52.51% (697) | PE-PGRS family protein |
M. tuberculosis H37Rv | Rv1803c | PE_PGRS32 | e-166 | 52.56% (664) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1797 | PE_PGRS31 | 0.0 | 98.88% (624) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-111 | 42.86% (658) | triple helix repeat-containing collagen |
M. leprae Br4923 | MLBr_01183 | - | 1e-11 | 34.38% (96) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 1e-46 | 34.24% (476) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_2645 | - | 0.0 | 73.72% (624) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 2e-24 | 41.29% (201) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 8e-95 | 40.59% (611) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_4332 | - | 3e-41 | 37.70% (382) | PUTATIVE - |
M. ulcerans Agy99 | MUL_0212 | - | 1e-163 | 52.56% (664) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-108 | 41.45% (690) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Rv1768|M.tuberculosis_H37Rv -------------------------------------------------- Mb1797|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2645|M.marinum_M -------------------------------------------------- MUL_0212|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv1768|M.tuberculosis_H37Rv -------------------------------------------------- Mb1797|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2645|M.marinum_M -------------------------------------------------- MUL_0212|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv1768|M.tuberculosis_H37Rv -------------------------------------------------- Mb1797|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2645|M.marinum_M -------------------------------------------------- MUL_0212|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv1768|M.tuberculosis_H37Rv -------------------------------------------------- Mb1797|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2645|M.marinum_M -------------------------------------------------- MUL_0212|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv1768|M.tuberculosis_H37Rv -------------------------------------------------- Mb1797|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2645|M.marinum_M -------------------------------------------------- MUL_0212|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv1768|M.tuberculosis_H37Rv ---------MSYLVVVPELVAAAATDLANIG------------------- Mb1797|M.bovis_AF2122/97 ---------MSYLVVVPELVAAAATDLANIG------------------- MMAR_2645|M.marinum_M ---------MSYLIAAPEMVAAAATDLASVG------------------- MUL_0212|M.ulcerans_Agy99 ---------MSFVNVTPEAVAAAASDLTGIG------------------- MLBr_01183|M.leprae_Br4923 --------MPLFLNAEPQALTAAANTLEGLS------------------- Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG TH_4332|M.thermoresistible__bu ---------MPFITSGAAFVGGAAMLLAGPG------------------- MAB_4284c|M.abscessus_ATCC_199 ------MSIIDFILNLFRDPVEAASYVADPEAALAN-------------- MAV_4827|M.avium_104 -------MNIVLGVSMAPSSIQMVVLEGEYADG----------------- . Rv1768|M.tuberculosis_H37Rv -----------------------SSISAANAAAAAPTTALVAAGGDEVSA Mb1797|M.bovis_AF2122/97 -----------------------SSISAANAAAAAPTTALVAAGGDEVSA MMAR_2645|M.marinum_M -----------------------SSISAANAAAAAPTMSVLAAGADEVSA MUL_0212|M.ulcerans_Agy99 -----------------------SVLGEANAVAARATTTVLAAGGDEVSA MLBr_01183|M.leprae_Br4923 -----------------------AATVASNAAAAQLTTEIAPPAADDVSI Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG TH_4332|M.thermoresistible__bu ------------------------GVSALEAAGSAPR-TVEYEYSLVACD MAB_4284c|M.abscessus_ATCC_199 -----------------------AGLSAVSAAQVGAVMPVVAESVASNYG MAV_4827|M.avium_104 -----------------------ATVEEDAIDVTGADDAATASAPDRVIS Rv1768|M.tuberculosis_H37Rv AIAALFGAHARAYQALSAQAAMFHEQFVRALAAGG--------------- Mb1797|M.bovis_AF2122/97 AIAALFGAHARAYQALSAQAAMFHEQFVRALAAGG--------------- MMAR_2645|M.marinum_M VVAALFDAHAQAYQSLSAQAALFHEQFVQALNAGA--------------- MUL_0212|M.ulcerans_Agy99 AIAALFSFHGQSYQTLGAQAEAFHAQFAQLMANGA--------------- MLBr_01183|M.leprae_Br4923 LLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSS--------------- Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT TH_4332|M.thermoresistible__bu STLPLMCEAGDSVGGLGGASHDRSAFSASALGMAS--------------- MAB_4284c|M.abscessus_ATCC_199 YQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSP--------------- MAV_4827|M.avium_104 AILGTREGAADAGLQLSSIGVTWTDQLEAAALRDA--------------- . Rv1768|M.tuberculosis_H37Rv -NSYAVAEAATAQSVQQDLLNLINAPTQALLGRP---------------- Mb1797|M.bovis_AF2122/97 -NSYAVAEAATAQSVQQDLLNLINAPTQALLGRP---------------- MMAR_2645|M.marinum_M -GSYALAEAASVS-PLQDALNLINAPTQALFGRP---------------- MUL_0212|M.ulcerans_Agy99 -GTYASAEAANAA-PFQGLLGAVNAPVQTLTGRP---------------- MLBr_01183|M.leprae_Br4923 -SAYAGTETANHDSL----------------------------------- Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------ Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------ MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH TH_4332|M.thermoresistible__bu FGPDWNPGGAFLGLIGPGGLLIGDGLNGTDAYID---------------- MAB_4284c|M.abscessus_ATCC_199 -SLLSPRDNDFLSHNDTDFASHNPIASGNQVMSP---------------- MAV_4827|M.avium_104 -LAARRIDNVMLVSAFLAAAALAQNVGGAMGYER---------------- Rv1768|M.tuberculosis_H37Rv -LIGNGANGLPGTGQNGGDGGILYGNG-----GNGGSGGVNQAGGNGGNA Mb1797|M.bovis_AF2122/97 -LIGNGANGLPGTGQNGGDGGILYGNG-----GNGGSGGVNQAGGNGGNA MMAR_2645|M.marinum_M -LIGNGADGAPGTGQSGGNGGFLYGNG-----GNGGSGANNQGGGNGGSA MUL_0212|M.ulcerans_Agy99 -LIGNGANGAPGTGANGGAGGWLIGNG-----GAGGSGAPGLNGGAGGAA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS TH_4332|M.thermoresistible__bu ------ENGVFHEATRGGNGGLLWGNG--------------GKGGNGLDA MAB_4284c|M.abscessus_ATCC_199 --SGNVDSFNRGPLLDLSFGDLQFGNR----DTTAIGDGAVAVGGSNSGP MAV_4827|M.avium_104 ------TAVLLVEPDTATLAVVETSDG-------SIPDVYKQQIRAESYG Rv1768|M.tuberculosis_H37Rv GLWGNGGSGGAG-------------------GNATTAGRNGFNGGAGGSG Mb1797|M.bovis_AF2122/97 GLWGNGGSGGAG-------------------GNATTAGRNGFNGGAGGSG MMAR_2645|M.marinum_M GLWGNGGAGGAG-------------------GDSTVAGVNGFNGGAGGSG MUL_0212|M.ulcerans_Agy99 GLIGTGGAGGAG-------------------GSSSTV--NGGLGGTGGAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY TH_4332|M.thermoresistible__bu GLYTVPDPDNPG--------------------STIQMYFEASDGADGGRG MAB_4284c|M.abscessus_ATCC_199 IASGQGSTAVNG-------------------DVRDSNIINADHGSNVGVD MAV_4827|M.avium_104 DAAGQLSAMVAG-----------------------LEKLESLPGGLLLVG Rv1768|M.tuberculosis_H37Rv -------------------------------------------------- Mb1797|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2645|M.marinum_M -------------------------------------------------- MUL_0212|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG----------- Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG----------- MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv1768|M.tuberculosis_H37Rv -GLLWGNGGAGGAGGNGGPAPLVGG------------------VGTTGGA Mb1797|M.bovis_AF2122/97 -GLLWGNGGAGGAGGHGGPAPLVGG------------------VGTTGGA MMAR_2645|M.marinum_M -GLLWGNGGAGGAGGNGGGAPLAGF------------------VGTSGGN MUL_0212|M.ulcerans_Agy99 -GWLLGNGGAGGAGG-ASAIPLGPD------------------LIGKGGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV TH_4332|M.thermoresistible__bu -GFLFGNGGDGGNGGNVGGK--------------------------NGAD MAB_4284c|M.abscessus_ATCC_199 -QSQTRVGGDYTNVSGHGSADIDKS------------------VTVVDDH MAV_4827|M.avium_104 SGVDVAPLKQVLQTTTFLDVSVAEE-------------------PETALA Rv1768|M.tuberculosis_H37Rv GGNGG--GAGLFYG---------------FGGAGGNGG------------ Mb1797|M.bovis_AF2122/97 GGNGG--GAGLFYG---------------FGGAGGNGG------------ MMAR_2645|M.marinum_M GGNGG--GAGLLYG---------------YGGAGGAGG------------ MUL_0212|M.ulcerans_Agy99 GGPGGLFGAGGLGG---------------AGGFGGSGGG----------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD----------- Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN----------- MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP TH_4332|M.thermoresistible__bu PVTATVAADKSVAG-----------------GNGGNGGR----------- MAB_4284c|M.abscessus_ATCC_199 SQRNTTNINDSFNT--------------DRSTNIGSGNT----------- MAV_4827|M.avium_104 RGAALAAANAPLFAS-----------STAALAYAQDPGTG---------- Rv1768|M.tuberculosis_H37Rv ----------------MGGVAPSTGPSMGILPAGG--------------- Mb1797|M.bovis_AF2122/97 ----------------MGGVAPSTGPSMGILPAGG--------------- MMAR_2645|M.marinum_M ----------------TGGVAPPTGVGQTILSAGG--------------- MUL_0212|M.ulcerans_Agy99 ----------------AGGQGGAGGLLSGLVGAGGG-------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG--------------- Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG--------------- MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ TH_4332|M.thermoresistible__bu -----------------------GGLLFGLGGNGG--------------- MAB_4284c|M.abscessus_ATCC_199 ---------------TNTEIGSHNQANIGTSTSAGG-------------- MAV_4827|M.avium_104 ---------------AVDQYSLPDYLYVPVDPEPGD-------------- Rv1768|M.tuberculosis_H37Rv --VGGPGGSGG--ASALAFGSGGVGGAGGLGG-----PTDGTVQGVGGF- Mb1797|M.bovis_AF2122/97 --VGGPGGSGG--ASALAFGSGGVGGAGGLGG-----PTDGTVQGVGGF- MMAR_2645|M.marinum_M --VGGTGGAGG--GGAALIGFGGAGGTGGTGG-----LSDTTTETIGGY- MUL_0212|M.ulcerans_Agy99 --HGGTGGYGGGAGGAGATGGGNTGGIGGDGGSAGMLFSNSGAGGAGGAS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG TH_4332|M.thermoresistible__bu --NGGWSTTSYLDARGGNGGNGGLGGVLRPGGLLSLLLPSGAASEPGGLF MAB_4284c|M.abscessus_ATCC_199 --SAAVGGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG MAV_4827|M.avium_104 -DELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSGLAVVGIS Rv1768|M.tuberculosis_H37Rv ----GGQGGNGGQSGLLFGNAGAGGAGAAGGAGTGDTESFGGHGGAGGDG Mb1797|M.bovis_AF2122/97 ----GGQGGNGGQSGLLFGNAGAGGAGAAGGAGTGDTESFGGHGGAGGDG MMAR_2645|M.marinum_M ----GGMGGLGGQSGVLFGTPGAGGAGGAGGAGVGTFASPGGHGGSGGDA MUL_0212|M.ulcerans_Agy99 ELADGGAGGAGGNGGWLLSNGGVGGAGGAGADAVGPPFGIPAGSGSGGGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGT Mvan_1264|M.vanbaalenii_PYR-1 --GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGT MSMEG_0868|M.smegmatis_MC2_155 --GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGN TH_4332|M.thermoresistible__bu ------TGGNGGNGGLAIANHWVGITDGVPGPD----------------- MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNA MAV_4827|M.avium_104 -------AVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAPAPPPVQ Rv1768|M.tuberculosis_H37Rv GAVG----------LIGNGG------AGGTGSPGAVVGGNGG-------- Mb1797|M.bovis_AF2122/97 GAVG----------LIGNGGGGGNGGAGGTGSPGAVVGGNGG-------- MMAR_2645|M.marinum_M GAIG----------LFGNGAAGGDGGIGGDGASGGNDGGNGG-------- MUL_0212|M.ulcerans_Agy99 GGAGGV--------FFGNGG------AGGAGGTGGDGGGTGG-------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG-------- Mvan_1264|M.vanbaalenii_PYR-1 GGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG-------- MSMEG_0868|M.smegmatis_MC2_155 GGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATV TH_4332|M.thermoresistible__bu ----------------------------DDAVSSSAYGGHGG-------- MAB_4284c|M.abscessus_ATCC_199 GLAG-------------NAGLAGNAGLAGNAGLAGNAGLAGN-------- MAV_4827|M.avium_104 ASAPQP--------KISVPEPVAAPKPLSPPVAAPLPAAPPP-------- Rv1768|M.tuberculosis_H37Rv ---------VGGLGGAGSPGGLLYGTG----------------------- Mb1797|M.bovis_AF2122/97 ---------VGGLGGAGSPGGLLYGTG----------------------- MMAR_2645|M.marinum_M ---------VGGLGGVGGPGGWIFGTG----------------------- MUL_0212|M.ulcerans_Agy99 ---------AGGAAGNG----VLIGNG----------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ---------TGGTGGQGG-LGGGGGTG----------------------- Mvan_1264|M.vanbaalenii_PYR-1 ---------TGGTGGQGG-LGGVGGTG----------------------- MSMEG_0868|M.smegmatis_MC2_155 IGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATD TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------AGLAGNAAVAGNAAVAG----------------------- MAV_4827|M.avium_104 ---------AAPPLPEAPPIPAAPPVVP---------------------- Rv1768|M.tuberculosis_H37Rv ---GAGGNGGPGGDGGTG-ATVGFA-------GSGGFGGAGGIAQLFGTG Mb1797|M.bovis_AF2122/97 ---GAGGNGGPGGDGGTG-ATVGFA-------GSGGFGGAGGIAQLFGTG MMAR_2645|M.marinum_M ---GAGGNGGLGGSGGTGVVTNGFA-------GSGGFGGAGGDAQFLGFG MUL_0212|M.ulcerans_Agy99 ---GNGGIGGAAGLWGTG-GTGGSG-------GSGGTGATGGFSGLLASG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFG Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFG MSMEG_0868|M.smegmatis_MC2_155 GHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNG TH_4332|M.thermoresistible__bu ----HGAGPGSGGNGGSAVANSLGN-------AIAGNGGDAGRFVLIGPG MAB_4284c|M.abscessus_ATCC_199 -NAAVAGNAAVGGVLNTGVSGAIGGS---SHVGGAINESLGGSGSVGGST MAV_4827|M.avium_104 -VPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPP Rv1768|M.tuberculosis_H37Rv GMGGSGGGIGAGTTTVVPPDVAPVGG-----TGGNGGRAGLLLGVGGMGG Mb1797|M.bovis_AF2122/97 GMGGSGGGIGAGTTTVVPPDVAPVGG-----TGGNGGRAGLLLGVGGMGG MMAR_2645|M.marinum_M GTGGSGGGIGAGETAAVPLTTQPVGG-----TGGNGGRAGLFFGVGGTGG MUL_0212|M.ulcerans_Agy99 DGGAGGAGGAGGAGGLLDGLVGAGGG-----DGGAGGNAGTLFGSGGVGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAG Mvan_1264|M.vanbaalenii_PYR-1 GVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAG MSMEG_0868|M.smegmatis_MC2_155 GDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGS TH_4332|M.thermoresistible__bu GNGGNGGTGLXXX--------------------------------PRPRR MAB_4284c|M.abscessus_ATCC_199 AVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHT MAV_4827|M.avium_104 SPPQVGGTVPQSPPQHQTPPGEGTPP----KPDGPGNYGGGHVPTPGAGG Rv1768|M.tuberculosis_H37Rv NGGATSVGGTLYAAGGNGGDGGLVWGN------------------GGTGG Mb1797|M.bovis_AF2122/97 NGGATSVGGTLYAAGGNGGDGGLVWGN------------------GGTGG MMAR_2645|M.marinum_M NGGATSTNGALYATGGNGGDGGLIFGN------------------GGTGG MUL_0212|M.ulcerans_Agy99 DGGSGHGNG---GDGGGGGNAGLLFSD------------------AGGGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK KAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGA Mvan_1264|M.vanbaalenii_PYR-1 TAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGS MSMEG_0868|M.smegmatis_MC2_155 TLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGD TH_4332|M.thermoresistible__bu RRNHRRTRRRPNGRRPRPPPGR---------------------------- MAB_4284c|M.abscessus_ATCC_199 GVGGGVSTGVGVGSHVGGGISESLGGS------------------GSVGG MAV_4827|M.avium_104 SGGSGGGHVPTPGAGGSGGSG--------------------------GGH Rv1768|M.tuberculosis_H37Rv SGGAGGAGSVGNGG------------------AGGNAALLFGNGGAGGAG Mb1797|M.bovis_AF2122/97 SGGAGGAGSVGNGG------------------AGGNAALLFGNGGAGGAG MMAR_2645|M.marinum_M NGGAGGGTSVGAGG------------------QGGAASAFFGNGGAGGDG MUL_0212|M.ulcerans_Agy99 FGGFGLAGGGGTGG------------------SGGDAG-WLGSGGAGGAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK TGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAG Mvan_1264|M.vanbaalenii_PYR-1 AGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAG MSMEG_0868|M.smegmatis_MC2_155 GGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADG TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 STAVGGGAHTGVGG---------------GVNTGVGVGSHVGGGISESLG MAV_4827|M.avium_104 VPTPGTGGPGGTGG------------------SGGGHVPTPGAGTPGGSG Rv1768|M.tuberculosis_H37Rv GA---GGIGAGG--------------AGGFGAVLFGNGGAGGSG------ Mb1797|M.bovis_AF2122/97 GA---GGIGAGG--------------AGGFGAVLFGNGGAGGSG------ MMAR_2645|M.marinum_M GA---GGQGAGG--------------AGGSGALFFGNGGAGGNG------ MUL_0212|M.ulcerans_Agy99 GISVNGDAGAGG--------------AGGTSGQLLGDGGAGGAGG----- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK KAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG----- Mvan_1264|M.vanbaalenii_PYR-1 KAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG----- MSMEG_0868|M.smegmatis_MC2_155 WVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVW TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GSGSVGGSTAVG-------------GGAHTSAINDALGGSGSVGG----- MAV_4827|M.avium_104 GGHLPFPGAGST--------------PGGSGGGHLPTPGAGTPGG----- Rv1768|M.tuberculosis_H37Rv -----------APGGIG-AGGNGGN--------ALLVGNGGNGGAGTGGA Mb1797|M.bovis_AF2122/97 -----------APGGIG-AGGNGGN--------ALLVGNGGNGGAGTGGA MMAR_2645|M.marinum_M -----------APGGTG-VGGTGGS--------AVLIGNGGDGGDGTGGA MUL_0212|M.ulcerans_Agy99 -------EAELAAGGAGGSGGVGGD--------AVLIGAGGNGGNGGPGT MLBr_01183|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGA Mvan_1264|M.vanbaalenii_PYR-1 ------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGA MSMEG_0868|M.smegmatis_MC2_155 KSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGS TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGA MAV_4827|M.avium_104 --------------GLGGFGGGHAP----------APGGGLGGGGGHAPA Rv1768|M.tuberculosis_H37Rv AG-GAGGSG--GLLFGQNGMPGP------ Mb1797|M.bovis_AF2122/97 AG-GAGGSG--GLLFGQNGMPGP------ MMAR_2645|M.marinum_M AG-GAGGSG--GFIFGQNGSNGLP----- MUL_0212|M.ulcerans_Agy99 AK-GDPGSGGAGGLLGVDGLNGLS----- MLBr_01183|M.leprae_Br4923 ----------------------------- Mflv_5091|M.gilvum_PYR-GCK G--GAGGSGGSGGSGGSGGSGGAAGDSDD Mvan_1264|M.vanbaalenii_PYR-1 G--GAGGSGGSGGSGGAGGSGGAAGDSD- MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGGNGGADGTPGTAGTTGANNP TH_4332|M.thermoresistible__bu ----------------------------- MAB_4284c|M.abscessus_ATCC_199 AGTGFEAQGHAQGHASETAHTTLPGAEHH MAV_4827|M.avium_104 PGGGLGGFGGGHSGGGLGGLGGGHK----