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VSFVNVTPEAVAAAASDLTGIGSVLGEANAVAARATTTVLAAGGDEVSAAIAALFSFHGQSYQTLGAQAE AFHAQFAQLMANGAGTYASAEAANAAPFQGLLGAVNAPVQTLTGRPLIGNGANGAPGTGANGGAGGWLIG NGGAGGSGAPGLNGGAGGAAGLIGTGGAGGAGGSSSTVNGGLGGTGGAGGWLLGNGGAGGAGGASAIPLG PDLIGKGGAGGPGGLFGAGGLGGAGGFGGSGGGAGGQGGAGGLLSGLVGAGGGHGGTGGYGGGAGGAGAT GGGNTGGIGGDGGSAGMLFSNSGAGGAGGASELADGGAGGAGGNGGWLLSNGGVGGAGGAGADAVGPPFG IPAGSGSGGGAGGAGGVFFGNGGAGGAGGTGGDGGGTGGAGGAAGNGVLIGNGGNGGIGGAAGLWGTGGT GGSGGSGGTGATGGFSGLLASGDGGAGGAGGAGGAGGLLDGLVGAGGGDGGAGGNAGTLFGSGGVGGDGG SGHGNGGDGGGGGNAGLLFSDAGGGGFGGFGLAGGGGTGGSGGDAGWLGSGGAGGAGGISVNGDAGAGGA GGTSGQLLGDGGAGGAGGEAELAAGGAGGSGGVGGDAVLIGAGGNGGNGGPGTAKGDPGSGGAGGLLGVD GLNGLS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0212 | - | - | 100% (636) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_3062 | - | 0.0 | 51.54% (780) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_4280 | - | 0.0 | 51.31% (764) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0767 | PE_PGRS9 | 0.0 | 52.02% (817) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-121 | 44.02% (686) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0746 | PE_PGRS9 | 0.0 | 51.26% (796) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-12 | 35.87% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 3e-46 | 33.60% (491) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4398 | - | 0.0 | 69.55% (762) | PE-PGRS family protein, PE_PGRS9_3 |
| M. avium 104 | MAV_4827 | - | 7e-25 | 42.50% (200) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 6e-93 | 40.03% (662) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-42 | 41.20% (301) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-118 | 44.21% (665) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4398|M.marinum_M --------------------------------------------------
Mb0767|M.bovis_AF2122/97 --------------------------------------------------
Rv0746|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4398|M.marinum_M --------------------------------------------------
Mb0767|M.bovis_AF2122/97 --------------------------------------------------
Rv0746|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4398|M.marinum_M --------------------------------------------------
Mb0767|M.bovis_AF2122/97 --------------------------------------------------
Rv0746|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4398|M.marinum_M --------------------------------------------------
Mb0767|M.bovis_AF2122/97 --------------------------------------------------
Rv0746|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 ------------------------------------MSFVNVTPEAVAAA
MMAR_4398|M.marinum_M ------------------------------------MSFVNVTPEAVAAA
Mb0767|M.bovis_AF2122/97 ------------------------------------MSFVLAMPEVLGSA
Rv0746|M.tuberculosis_H37Rv ------------------------------------MSFVLAMPEVLGSA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS
MUL_0212|M.ulcerans_Agy99 ASDLTGIGSVLGEANAVAARATTTVLAAGGDEVSAAIAALFSFHGQSYQT
MMAR_4398|M.marinum_M ASDLTGIGSVLGEANAVAARATTTVLAAGGDEVSAAIAALFSFHGQSYQT
Mb0767|M.bovis_AF2122/97 ATDLAALGSVLGAADAAAAATTTGIVAAVQDEVSAAIAALFSAHGRAYQV
Rv0746|M.tuberculosis_H37Rv ATDLAALGSVLGAADAAAAATTTGIVAAAQDEVSAAIAALFSAHGRAYQV
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MLBr_01183|M.leprae_Br4923 -------MPLFLNAEPQALTAAANTLEG---LSAATVASNAAAAQLTTEI
MAB_4284c|M.abscessus_ATCC_199 VEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVN
MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
MUL_0212|M.ulcerans_Agy99 LGAQAEAFHAQFAQLMANGAGTYASAEAANAAPFQG--------LLGAVN
MMAR_4398|M.marinum_M LGAQAEAFHAQFAQLMANGAGTYASAEAANAAPFQG--------LLGAVN
Mb0767|M.bovis_AF2122/97 ASAQAAAVHAQFVEALSAGAGAYASAEAAGAAVLANPAQSVQQDLLAAVN
Rv0746|M.tuberculosis_H37Rv ASAQAAAVHAQFVEALSAGAGAYASAEAAGAAVLANPAQSVQQDLLAAVN
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MLBr_01183|M.leprae_Br4923 APPAADDVSILLAHFFSGHGRQYQAHASQG--------------ATNHQD
MAB_4284c|M.abscessus_ATCC_199 TGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHN
MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
MUL_0212|M.ulcerans_Agy99 APVQTLTGRPLIGNGANGAPGTGANGGAGGWLIGNGGAGGSGAP--GLNG
MMAR_4398|M.marinum_M APVQTLTGRPLIGNGANGAPGTGANGGAGGWLIGNGGAGGSGAP--GLNG
Mb0767|M.bovis_AF2122/97 AQSVALTGRPLIGNGANGAPGTGANGAPGGWLLGNGGAGGSAAAGSGLPG
Rv0746|M.tuberculosis_H37Rv AQSVALTGRPLIGNGANGAPGTGANGAPGGWLLGNGGAGGSAAAGSGLPG
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAG--AAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAG--AAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAG--NGGDGGNGGFGYVLIAGPN
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAG--NGGNGG-------------
MLBr_01183|M.leprae_Br4923 LIQSLLTS---------------SSAYAG---------------------
MAB_4284c|M.abscessus_ATCC_199 PIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIG--------
MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP-------------
MUL_0212|M.ulcerans_Agy99 GAGGAAGLIGTGGAGGAGGSSSTVNGGLGGTGGAGG-------------W
MMAR_4398|M.marinum_M GAGGAAGLIGTGGAGGAGGSSSTVNGGVGGTGGAGG-------------W
Mb0767|M.bovis_AF2122/97 GAGGAAGLFGTGGAGGAGGSSTVGDGGAGGAGGSGG-------------W
Rv0746|M.tuberculosis_H37Rv GAGGAAGLFGTGGAGGAGGSSTVGDGEAGGAGGSGG-------------W
Mflv_5091|M.gilvum_PYR-GCK -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155 VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu --NGYRTTDNNALDGGHGG-------------------------------
MLBr_01183|M.leprae_Br4923 --------TETANHDSL---------------------------------
MAB_4284c|M.abscessus_ATCC_199 --DGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIIN--------------
MAV_4827|M.avium_104 --DVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPG--------------
MUL_0212|M.ulcerans_Agy99 LLGNGGAGGAGGASAIPLGPDLIGKGGAG-----------------GPGG
MMAR_4398|M.marinum_M LLGNGGAGGAGGASAIPLGPDLIGKGGAGG--------------AGGSGG
Mb0767|M.bovis_AF2122/97 LLGTGGVGGVGG-----LGAGAGGAGGVG-----------------GAGG
Rv0746|M.tuberculosis_H37Rv LLGTGGVGGVGG-----LGAGAGGAGGVG-----------------GAGG
Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG------TVGTAGATGGTG---------------TGANGG
Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG------AAGTAGATGGTG---------------VGGNGG
MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG
TH_3810|M.thermoresistible__bu --------------------------------------------NGGNVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------ADHGSNVGVDQ------------SQTRVGGD
MAV_4827|M.avium_104 ------------------------------------------------GL
MUL_0212|M.ulcerans_Agy99 LFGAGGLGGAGGFG----------------------GSGGGAGGQGGAGG
MMAR_4398|M.marinum_M LFGAGGLGGAGGFG----------------------GSAGGAGGQGGAGG
Mb0767|M.bovis_AF2122/97 LLGAGGHGGAGGLG----------------------AVTGGVGGAGGAGG
Rv0746|M.tuberculosis_H37Rv LLGAGGHGGAGGLG----------------------AVTGGVGGTGGAGG
Mflv_5091|M.gilvum_PYR-GCK AGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGG
Mvan_1264|M.vanbaalenii_PYR-1 AGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGG
MSMEG_0868|M.smegmatis_MC2_155 HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGE
TH_3810|M.thermoresistible__bu FFSLFNLGG--------------------AGGWGGSGVDG----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 YTNVSGHGSADIDK----------------------SVTVVDDHSQRNTT
MAV_4827|M.avium_104 LLVGSGVDVAPLKQ----------------------VLQTTTFLDVSVAE
MUL_0212|M.ulcerans_Agy99 LLSGLVGAGGGHGGTGGYG----GGAGGAG--------------------
MMAR_4398|M.marinum_M LLSGLVGAGGGHGGTGGYG----GGAGGAGGNAGLLAGTGGSGGTGGYGG
Mb0767|M.bovis_AF2122/97 LLAGLLAGPGGAGGTGGRGFLNDGGVGGAGGNAG----------------
Rv0746|M.tuberculosis_H37Rv LLAGLLAGPGGAGGTGGRGFLNNGGVGGAGGNAG----------------
Mflv_5091|M.gilvum_PYR-GCK Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1 Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPT-------
TH_3810|M.thermoresistible__bu -----------VDVVGGNP-------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NINDSFNTDRSTNIGSGNTTNTEIGSHNQAN-------------------
MAV_4827|M.avium_104 EPETALARGAALAAANAPLFASSTAALAYAQ-------------------
MUL_0212|M.ulcerans_Agy99 ----------------------ATGGGNTGGIGGDGGSAGMLFS------
MMAR_4398|M.marinum_M GAGGAGGNAGLLFGNGGAGGAGATGGGNTGGIGGDGGNAGMLFS------
Mb0767|M.bovis_AF2122/97 ----------LLFGAGGTGGSGGAGLGGDGGAGGAGGNAGVLFG------
Rv0746|M.tuberculosis_H37Rv ----------LLFGAGGTGGSGGAGLGGDGGAGGAGGNTGVLFG------
Mflv_5091|M.gilvum_PYR-GCK ---------------------LQGGKGGDGGAGGKGGDADSMGS------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------LQGGQGGDGGTGGTGGDATSMGE------
MSMEG_0868|M.smegmatis_MC2_155 ----------TGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVA
TH_3810|M.thermoresistible__bu ----------------------------DGGTPG----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------IGTSTSAGGSAAVGGNAGLAGN------
MAV_4827|M.avium_104 -------------------------DPGTGAVDQYSLPDYLYVP------
MUL_0212|M.ulcerans_Agy99 ---------------NSGAGGAGGASELADGGAG----------------
MMAR_4398|M.marinum_M ---------------NGGAGGAGGASELADGGAG----------------
Mb0767|M.bovis_AF2122/97 ---------------NAGSGGTGGFGD-TDGGAG----------------
Rv0746|M.tuberculosis_H37Rv ---------------NAGSGGTGGFGD-TDGGAG----------------
Mflv_5091|M.gilvum_PYR-GCK ------------AGATGGKGGNGGNGGRGGLFG---------------KG
Mvan_1264|M.vanbaalenii_PYR-1 ------------AGATGGKGGNGGNGGRGSLFG---------------RG
MSMEG_0868|M.smegmatis_MC2_155 TGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQG
TH_3810|M.thermoresistible__bu --------------AHGESHTPGVYTDRQ---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------AGLAGNAGLAGNAGLAGN----------------
MAV_4827|M.avium_104 ------------------VDPEPGDDELAYSAVG----------------
MUL_0212|M.ulcerans_Agy99 -------------------------------GAGGNGGWLLSNGGVGGAG
MMAR_4398|M.marinum_M -------------------------------GAGGNGGWLLSNGGVGGAG
Mb0767|M.bovis_AF2122/97 -------------------------------GAGGDAGWLGS-GGVGGAG
Rv0746|M.tuberculosis_H37Rv -------------------------------GAGGDAGWLGS-GGVGGAG
Mflv_5091|M.gilvum_PYR-GCK GNAGNGAD----------------------GGTGGAGGAGGTGG-TGGAG
Mvan_1264|M.vanbaalenii_PYR-1 GNAGNGGN----------------------GGTGGNGGNGGTGG-TGGNG
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRG
TH_3810|M.thermoresistible__bu ----------------------------------GEDGEDGTGTGIGGRG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------AGLAGNAGLAGNAGLAGNAG
MAV_4827|M.avium_104 ----------------------------------EEDAESPTVVIEKLFL
MUL_0212|M.ulcerans_Agy99 GAGADAV--------GPPFGIPAGSGSGGGAG-----GAGGVFFGNGGAG
MMAR_4398|M.marinum_M GAGADAV--------GPPFGIPAGSGGNGGAG-----GAGGVFFGNGGAG
Mb0767|M.bovis_AF2122/97 GFG------------------ETGDGGVGGAG-----GKAGLLIGNGGAG
Rv0746|M.tuberculosis_H37Rv GFG------------------ETGDGGVGGAG-----GKAGLLIGNGGAG
Mflv_5091|M.gilvum_PYR-GCK GTGG-----------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GTGG-----------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAG
TH_3810|M.thermoresistible__bu GNGG----------------SSSGTHPMAEDG--------EHVKALDGRP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGN-----------------AGLAGNAGLAGNAGLAGNAGLAGNAGLAG
MAV_4827|M.avium_104 PEDS-----------------EPRRRPVLLVGSGLAVVGISAVLALEIAL
MUL_0212|M.ulcerans_Agy99 GAGGTGGDGGGTGGAGGAAGNGVLIGNGGNGGIG----------------
MMAR_4398|M.marinum_M GAGGTGGDGGGIGGAGGAAGNGVLIGNGGNGGIGGIGLTPGADGIGGTSG
Mb0767|M.bovis_AF2122/97 GAG-------------------VLIGNGGNAGIGGTGPTAGDTGAGGISG
Rv0746|M.tuberculosis_H37Rv GAGGQGAVTGGTGGAG---GDGVLIGNGGNAGIGGTGPTAGDTGAGGISG
Mflv_5091|M.gilvum_PYR-GCK GTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GTG-GTGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNG
TH_3810|M.thermoresistible__bu GLD---GGNGSHGGNGGHGGRGGFLGIGGSG-------GWGGHGGNGGD-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NAG--LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG
MAV_4827|M.avium_104 AIGIRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAA
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4398|M.marinum_M LVLGLDGFNAPASTSPLHTLQQQALNAINAPVEAATGRPLIGNGTPGAAG
Mb0767|M.bovis_AF2122/97 LLLGADGFNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGTPGAVG
Rv0746|M.tuberculosis_H37Rv LLLGADGFNTPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGTPGAVG
Mflv_5091|M.gilvum_PYR-GCK ---------GTGGTGGTGGAG-----------DGTGGTGGTGG----TGG
Mvan_1264|M.vanbaalenii_PYR-1 ---------GTGGTGGTGGAG-----------DGLGGTGGTGG----TGG
MSMEG_0868|M.smegmatis_MC2_155 GTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGH
TH_3810|M.thermoresistible__bu ----------TDADGGNGGDG---------------GNGGSAG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------NAAVAGNAAVAG----------NAAVAGNAAVGG----VLN
MAV_4827|M.avium_104 PKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVP
MUL_0212|M.ulcerans_Agy99 --------------------------------GAAGLWGTGGTGGSGGSG
MMAR_4398|M.marinum_M SGADGTAGGWLLGDGGAGGSSTAGSGLDGGTGGAAGLWGTGGTGGAGGSG
Mb0767|M.bovis_AF2122/97 SGATGAPGGWLLGDGGAGGSGAAGSGAPGGAGGAAGLWGTGGAG------
Rv0746|M.tuberculosis_H37Rv SGATGAPGGWLLGDGGAGGSGAAGSGAPGGAGGAAGLWGTGGAGGAGGSS
Mflv_5091|M.gilvum_PYR-GCK QGGQGGQGG-----------------TGGTGGQGG-LGGGGGTG------
Mvan_1264|M.vanbaalenii_PYR-1 FGGQGGQGG-----------------TGGTGGQGG-LGGVGGTG------
MSMEG_0868|M.smegmatis_MC2_155 RGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIV
TH_3810|M.thermoresistible__bu --------------------------RGGTGGLRGVFGINGGNG------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TGVSGAIGG----------------SSHVGGAINESLGGSGSVG------
MAV_4827|M.avium_104 VRIPVPDP-----------------VSPPQLLAPPRLSVPQPVQP-----
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4398|M.marinum_M GTDSISGIAGGDGGAGGAGGWLSGTGGAGGSGGAGGDGGVLGSGDGGAGG
Mb0767|M.bovis_AF2122/97 ----------------GAGGWLLGDGGAGGIGG-----------------
Rv0746|M.tuberculosis_H37Rv AG------GGGAGGAGGAGGWLLGDGGAGGIGG-----------------
Mflv_5091|M.gilvum_PYR-GCK -----------------GQGGTGGTGGQGGTGG-----------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------GTGGTGGTGGQGGTGG-----------------
MSMEG_0868|M.smegmatis_MC2_155 AYNVVQANPQASGTATDGHGGSGINGGHGGNGG-----------------
TH_3810|M.thermoresistible__bu ------------------RAGLGGRGXXXXGGG-----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------GSTAVGGGAHTGVGG-----------------
MAV_4827|M.avium_104 ------------------PVRVPQPPSPPQVGG-----------------
MUL_0212|M.ulcerans_Agy99 -----------------GTGATG--------GFSGLLASG-DGGAG----
MMAR_4398|M.marinum_M AGGSGGAGGLLGAGGTGGTGAIG--------GFSGLLASG-DGGAG----
Mb0767|M.bovis_AF2122/97 -----------ASTVLGGTGGGG--------GVGGLWGAGGAGGAGGTGL
Rv0746|M.tuberculosis_H37Rv -----------ASTVLGGTGGGG--------GVGGLWGAGGAGGAGGTGL
Mflv_5091|M.gilvum_PYR-GCK ---------------TGGTGGTG--------GTGGAGGDGGLGGLGGFGG
Mvan_1264|M.vanbaalenii_PYR-1 ---------------TGGTGGTG--------GTGGAGGDGGLGGLGGFGG
MSMEG_0868|M.smegmatis_MC2_155 ---------------QGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGG
TH_3810|M.thermoresistible__bu ---------------VGAAVRSG---------------NGVFSGGGGTPS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------GVSTGVG---------VGSHVGGGISESLGGSGS
MAV_4827|M.avium_104 -----------------TVPQSP-------------PQHQTPPGEGTPPK
MUL_0212|M.ulcerans_Agy99 -----GAGGAGGAGGLLDGLVGAGGGDGGAG-------------------
MMAR_4398|M.marinum_M -----GAGGAGGAGGLLGGLVGAGGGDGGAGGTGGFHGDAVTGTAGAGGT
Mb0767|M.bovis_AF2122/97 VGGDGGAGGAGGTGGLLAGLIGAGGGHGGTGG---------LNTNGDGGV
Rv0746|M.tuberculosis_H37Rv VGGDGGAGGAGGTGGLLAGLIGAGGGHGGTGG---------LSTNGDGGV
Mflv_5091|M.gilvum_PYR-GCK SGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGK
Mvan_1264|M.vanbaalenii_PYR-1 VGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGT
MSMEG_0868|M.smegmatis_MC2_155 DGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGST
TH_3810|M.thermoresistible__bu AGFGVPTTIQFPAGSCTSRAVSREG------------------------I
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGSTAVGGGAHTGVGGGVSTGVGVGSHVGGG-----------ISESLGG
MAV_4827|M.avium_104 PDGPGNYGGGHVPTPGAGGSGGSGGGHVPTPG--------------AGGS
MUL_0212|M.ulcerans_Agy99 ---------------------------------------------GNAGT
MMAR_4398|M.marinum_M GGAGGDAGLLGGPGGAGGTGGTGGPNIDAGGVLGAPGNSGAGGAGGNAGT
Mb0767|M.bovis_AF2122/97 GGAGGNAGMLAGPGGAGGAGGDGE----------NLDTGGDGGAGGSAGL
Rv0746|M.tuberculosis_H37Rv GGAGGNAGMLAGPGGAGGAGGDGE----------NLDTGGDGGAGGSAGL
Mflv_5091|M.gilvum_PYR-GCK AGATGAAGASGGKGAQGATGAQGATG-----------------AQGATG-
Mvan_1264|M.vanbaalenii_PYR-1 AGVTGASGASGGKGAQGATGAQGATG-----------------AQGATG-
MSMEG_0868|M.smegmatis_MC2_155 LGGNATGTATAGKGGEASNGGVAGNGG-----------NALVMAAGTTGV
TH_3810|M.thermoresistible__bu MPSSRAASARAG--------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SGSVGGSTAVGGGAHTGVGGGVN--------------------TGVGVGS
MAV_4827|M.avium_104 GGSGGGHVPTPG--------------------------------------
MUL_0212|M.ulcerans_Agy99 LFGSGGVGGDGGSGHGNGGDGGGGG-----------NAGLLFSDAGGGGF
MMAR_4398|M.marinum_M LFGSGGVGGDGGSGHGNGGDGGGGG-----------NAGLLFSDAGGGGF
Mb0767|M.bovis_AF2122/97 LFGSGGAGGAGGFGF-LGGDGGAGG-----------NAGLLLSSGGAGGF
Rv0746|M.tuberculosis_H37Rv LFGSGGAGGAGGFGF-LGGDGGAGG-----------NAGLLLSSGGAGGF
Mflv_5091|M.gilvum_PYR-GCK ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-N
Mvan_1264|M.vanbaalenii_PYR-1 ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-N
MSMEG_0868|M.smegmatis_MC2_155 ATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGN
TH_3810|M.thermoresistible__bu AACASSTSRSRRSFCCSRA-------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HVGGGISESLGGSGSVGGSTAVGGG---------------AHTSAINDAL
MAV_4827|M.avium_104 TGGPGGTGGSGGGHVPTPGAGTPGG-----------SGGGHLPFPGAGST
MUL_0212|M.ulcerans_Agy99 GGFGLAGGGGTGGSGGDAGWLGSGGAGGAGGISVNGDAGAGGAGGTSGQL
MMAR_4398|M.marinum_M GGFGLAGGGGTGGSGGDAGWLGSGGAGGAGGISVNGDAGAGGAGGTSGQL
Mb0767|M.bovis_AF2122/97 GGFGTAGG--VGGAGGNAGWLGFGGAGGIGGIGGNANGGAGGNGGTGGQL
Rv0746|M.tuberculosis_H37Rv GGFGTAGG--VGGAGGNAGWLGFGGAG-----------------------
Mflv_5091|M.gilvum_PYR-GCK GANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGA
Mvan_1264|M.vanbaalenii_PYR-1 GANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGA
MSMEG_0868|M.smegmatis_MC2_155 GGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGD
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGSTAVGGGAHTSAIN----------------------------
MAV_4827|M.avium_104 PGGSGGGHLPTPGAGTPGGGLG----------------------------
MUL_0212|M.ulcerans_Agy99 LGDGGAGGAGGEAELAAGGAGGSGGVGGDAVLIGAGGNGGNGGPGTAK--
MMAR_4398|M.marinum_M LGDGGAGGAGGEAELAAGGAGGSGGVGGDAVLIGAGGNGGNGGPGTAK--
Mb0767|M.bovis_AF2122/97 WGSGGAGGEG-GAALSVGDTGGAGGVGGSAGLIGTGGNGGNGGTGANA--
Rv0746|M.tuberculosis_H37Rv ------------------------GVGGSAGLIGTGGNGGNGGTGANA--
Mflv_5091|M.gilvum_PYR-GCK GGAGG-----------AGGEGGEGGDGGKGGAGAEGGAGGGGGAGGSGAG
Mvan_1264|M.vanbaalenii_PYR-1 GGAGG-----------AGGEGGEGGAGGAGGDGSEGGAGGSGGAGGSGTG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------ESMNSSINASHSSSMNESFGSSMGSHGAAGTG--
MAV_4827|M.avium_104 ------------------------GFGGGHAPAPGGGLGGGGGHAPAP--
MUL_0212|M.ulcerans_Agy99 ------------GDPGSGGAGG-LLGVDGLNGLS-----
MMAR_4398|M.marinum_M ------------GDPGSGGAGG-PLGVDGLNGLS-----
Mb0767|M.bovis_AF2122/97 ------------GSPGTGGAGGLLLGQNGLNGLP-----
Rv0746|M.tuberculosis_H37Rv ------------GSPGTGGAGGLLLGQNGLNGLP-----
Mflv_5091|M.gilvum_PYR-GCK GAG-------GAGGSGGSGGSGGSGGSGGAAGDSDD---
Mvan_1264|M.vanbaalenii_PYR-1 GAG-------GAGGSGGSGGSGGAGGSGGAAGDSD----
MSMEG_0868|M.smegmatis_MC2_155 GTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ---------------------------------------
MLBr_01183|M.leprae_Br4923 ---------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------FEAQGHAQGHASETAHTTLPGAEHH---
MAV_4827|M.avium_104 -----------GGGLGGFGGGHSGGGLGGLGGGHK----