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M. tuberculosis H37Rv Rv1803c (PE_PGRS32)

annotation: PE-PGRS FAMILY PROTEIN
coordinates: 2044923 - 2046842
length: 639

WTSQMIVAPAFVDAAAKDLATIGSAISRANAEALVPITALLPAGADDVSAAIAALFATHGQAYQELSAHA
VAFHEQFVQLMSAGAAQYASAEAANSSPLQIVGQTALDAINSPVQTLTGRPLIGNGANGVAGTGQNGGDG
GWLYGNGGNGGSGGTGQNGGNGGSAGLWGSGGNGGQGGAGANGAAGQPGKAGGSGGNGGAGGWIYGHGGH
GGAGGNGGNATAPGGASAGFDGGAGGNGGSGGRGGLLFGNGGNGSVGGMGGQGTNDTAGDSAGSGGLGGN
GGNGAQGGWLIGNGGQGGDSGAGGGTDSTQTGVMNGASGGSAGIAGNGGDAGLVGNGGAGGNGGNGAAGS
ALGTTIFGGSGGVGGSGGDGGNGGWLFGSGASGGNGGQGGDAGTNGFAGFGGSAGGGGWVGAVNFGPISV
QGFGLFGHGGDGGNGGDVGAGSLSIQFGASGGDGGQGGVLYGNGGNGGNAGSGGGTGFEGSAGQGGAAIL
IGNGGAGGNGATGGTGVGNIIQEAGGDGSDGGAGGSGGLLFGSGGAGGIGGAGGVGGSGNDGGNGGDGGQ
GGASGLGIGNGGPGGSGGTGGAGGTGGSAGTGGAGGDGGNAALLIGTGGDGGDGVPPAPGGQGGKGGLIG
LPGQNGQP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1803cPE_PGRS32-100% (639)PE-PGRS FAMILY PROTEIN
M. tuberculosis H37RvRv1768PE_PGRS31e-16850.66% (683) PE-PGRS family protein
M. tuberculosis H37RvRv1091PE_PGRS22e-16747.12% (798) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1831cPE_PGRS32b0.0100.00% (540) hypothetical protein Mb1831c
M. gilvum PYR-GCKMflv_5091-1e-11746.65% (553) triple helix repeat-containing collagen
M. leprae Br4923MLBr_01183-3e-0932.97% (91) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-3e-4834.10% (478) hypothetical protein MAB_4284c
M. marinum MMMAR_3008-0.075.91% (635) PE-PGRS family protein
M. avium 104MAV_4827-7e-2041.40% (157) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-5e-9536.60% (746) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-8e-4137.58% (322) PUTATIVE -
M. ulcerans Agy99MUL_2250-0.075.75% (635) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-11846.08% (549) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Rv1803c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb1831c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_3008|M.marinum_M               --------------------------------------------------
MUL_2250|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb1831c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_3008|M.marinum_M               --------------------------------------------------
MUL_2250|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        --------------------------------------MWTSQMIVAPAF
Mb1831c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_3008|M.marinum_M               --------------------------------------MSILQVTVVPAV
MUL_2250|M.ulcerans_Agy99           --------------------------------------MSILQVTVVPAV
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        ------------------------------------------VDAAAKDL
Mb1831c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_3008|M.marinum_M               ------------------------------------------VEMAANDL
MUL_2250|M.ulcerans_Agy99           ------------------------------------------VEMAANDL
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------VEAASYVADP--
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        AT---------------------------------------IGSAISRAN
Mb1831c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_3008|M.marinum_M               AT---------------------------------------IGSTISQAN
MUL_2250|M.ulcerans_Agy99           AT---------------------------------------IGSTISQAN
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------EAALANAGLS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------------------------------------MNIVLGVS
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        AEALVPITALLP-----------AGADDVSAAIAALFATHGQAY------
Mb1831c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_3008|M.marinum_M               AAALAPITGLLP-----------AGTDEVSAGIAALFEAHGNAY------
MUL_2250|M.ulcerans_Agy99           AAALAPITGLLP-----------AGTDEVSAGIAALFEAHGNAY------
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AVSAAQVGAVMPVVAESVASNYGYQSQWVNTGN-PIHDLSGNLQNYYAAQ
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        ----QELSAHAVAFHEQFVQLMSAGAAQYASAEAANSSPLQIVGQTALDA
Mb1831c|M.bovis_AF2122/97           ---------------------------------------MQIVGQTALDA
MMAR_3008|M.marinum_M               ----QTLGAQTLALHEQFVKLMSGGAAQYAAAEAANASPLQTVEQAVLDL
MUL_2250|M.ulcerans_Agy99           ----QTLGAQTLALHEQFVKLMSGGAAQYAAAEAANASPLQTVEQAVLDL
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        INSPVQTLTGRPLIGN---GANGVAGTGQNGGDGG---------------
Mb1831c|M.bovis_AF2122/97           INSPVQTLTGRPLIGN---GANGVAGTGQNGGDGG---------------
MMAR_3008|M.marinum_M               INSPAVALTGRPLIGN---GADGAAGTGENGGDGG---------------
MUL_2250|M.ulcerans_Agy99           INSPAVALTGRPLIGN---GADGAAGTGENGGDGG---------------
Mflv_5091|M.gilvum_PYR-GCK          VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1       VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155      GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu      --------------------------VDGDGGSGG---------------
MAB_4284c|M.abscessus_ATCC_199      RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP--------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGS---------------
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        -------------------------------------------------W
Mb1831c|M.bovis_AF2122/97           -------------------------------------------------W
MMAR_3008|M.marinum_M               -------------------------------------------------W
MUL_2250|M.ulcerans_Agy99           -------------------------------------------------W
Mflv_5091|M.gilvum_PYR-GCK          VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1       VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155      VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------------------I
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        LYGN-------------GGNGGSGGTGQ--------------NGGNGGSA
Mb1831c|M.bovis_AF2122/97           LYGN-------------GGNGGSGGTGQ--------------NGGNGGSA
MMAR_3008|M.marinum_M               LIGN-------------GGNGGSGGVGQ--------------NGGSGGSA
MUL_2250|M.ulcerans_Agy99           LIGN-------------GGNGGSGGVGQ--------------NGGSGGSA
Mflv_5091|M.gilvum_PYR-GCK          AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1       AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155      AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu      ------------------RTGLFSKLSR---------------GGDGGDG
MAB_4284c|M.abscessus_ATCC_199      ASGQ-------------GSTAVNGDVRD-----------SNIINADHGSN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------IPDVYKQQIR------------------AESYG
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        GLWGSGGNGGQG-----------------GAGANGAAGQPGKAGGSGGN-
Mb1831c|M.bovis_AF2122/97           GLWGSGGNGGQG-----------------GAGANGAAGQPGKAGGSGGN-
MMAR_3008|M.marinum_M               GLWGRGGNGGLG-----------------GTGADGASGQAGSAGGAGGN-
MUL_2250|M.ulcerans_Agy99           GLWGRGGNGGLG-----------------GTGADGASGQAGSAGGAGGN-
Mflv_5091|M.gilvum_PYR-GCK          GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1       QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155      TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu      ---GLGGNGGHG-------------------GGTGIISLLSLAG------
MAB_4284c|M.abscessus_ATCC_199      VGVDQSQTRVGG-----------DYTNVSGHGSADIDKSVTVVDDHSQR-
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                DAAGQLSAMVAG-----------------LEKLESLPGGLLLVGSG----
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        -------------------------GGAGG--------------------
Mb1831c|M.bovis_AF2122/97           -------------------------GGAGG--------------------
MMAR_3008|M.marinum_M               -------------------------GGAGG--------------------
MUL_2250|M.ulcerans_Agy99           -------------------------GGAGG--------------------
Mflv_5091|M.gilvum_PYR-GCK          -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1       -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155      SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------NTTNINDS----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        --WIYGHGGHGGAGGNGGNATAPGG----------------ASAGFDGGA
Mb1831c|M.bovis_AF2122/97           --WIYGHGGHGGAGGNGGNATAPGG----------------ASAGFDGGA
MMAR_3008|M.marinum_M               --WIYGHGGDGGIGGAGGNATASGT----------------VPAGLDGGA
MUL_2250|M.ulcerans_Agy99           --WIYGHGGDGGIGGAGGNATASGS----------------VAAGLDGGA
Mflv_5091|M.gilvum_PYR-GCK          --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1       --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155      KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu      ---------NGGNGGNGYRTTDNNA--------------------LDGGH
MAB_4284c|M.abscessus_ATCC_199      --FNTDRSTNIGSGNTTNTEIGSHN---------------QANIGTSTSA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---VDVAPLKQVLQTTTFLDVSVAE------------------EPETALA
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        GGNGGSGGRGGLLF-----------------GNGGNGSV-----------
Mb1831c|M.bovis_AF2122/97           GGNGGSGGRGGLLF-----------------GNGGNGSV-----------
MMAR_3008|M.marinum_M               GGAGGSGGHAGLLF-----------------GNGGSGGL-----------
MUL_2250|M.ulcerans_Agy99           GGAGGSGGHAGLLF-----------------GNGGSGGL-----------
Mflv_5091|M.gilvum_PYR-GCK          GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1       GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155      GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu      GGNGGNVGFFSLFN------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGSAAVGGNAGLAG------------------NAGLAGN-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                RGAALAAANAPLFAS----------------STAALAYAQ----------
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        -----------GGMGGQGTNDTAG-DSAGSGGLGG---------------
Mb1831c|M.bovis_AF2122/97           -----------GGMGGQGTNDTAG-DSAGSGGLGG---------------
MMAR_3008|M.marinum_M               -----------GGVGGQATGATTSSDLGGVGGAGG---------------
MUL_2250|M.ulcerans_Agy99           -----------GGVGGQATGATTSSDLGGVGGAGG---------------
Mflv_5091|M.gilvum_PYR-GCK          -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155      AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu      -------------LGGAGGWGGSG--VDGVDVVGG---------------
MAB_4284c|M.abscessus_ATCC_199      -----------AGLAGNAGLAGNAGLAGNAGLAGN---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------DPGTGAVDQYSLPDYLYVPVDPEPGD--------------
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        --NGGNGAQGG--------WLIGNGGQGGDSGAGGGTDSTQTG--VMNGA
Mb1831c|M.bovis_AF2122/97           --NGGNGAQGG--------WLIGNGGQGGDSGAGGGTDSTQTG--VMNGA
MMAR_3008|M.marinum_M               --NGGSGAHGG--------WLIGNAGNGGDSGGGGGSDETQSG--VMNGA
MUL_2250|M.ulcerans_Agy99           --NGGSGAHGG--------WLIGNAGNGGDSGSGGGSDETQTG--VMNGA
Mflv_5091|M.gilvum_PYR-GCK          --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGT--GGTGG
Mvan_1264|M.vanbaalenii_PYR-1       --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGT--GGTGG
MSMEG_0868|M.smegmatis_MC2_155      TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGH--GGDGG
TH_3810|M.thermoresistible__bu      ---------------------NPDGGTPGAHGESHTPGVYTDR--QGEDG
MAB_4284c|M.abscessus_ATCC_199      ---AGLAGNAG---------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAG
MLBr_01183|M.leprae_Br4923          ------------------------------MPLFLNAEPQALT--AAANT
MAV_4827|M.avium_104                -DELAYSAVGEE-------DAESPTVVIEKLFLPEDSEPRRRPVLLVGSG
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        SGGSAGIAGNGGDAG-LVGNGGAGGNGGNGAAG--------SALG-TTIF
Mb1831c|M.bovis_AF2122/97           SGGSAGIAGNGGDAG-LVGNGGAGGNGGNGAAG--------SALG-TTIF
MMAR_3008|M.marinum_M               TGGSAGLAGGGGDAG-VIGNGGAGGSGGKGAAG--------STLGGASIF
MUL_2250|M.ulcerans_Agy99           TGGSAGLAGGGGDAG-VIGNGGAGGSGGKGAAG--------STLGGASIF
Mflv_5091|M.gilvum_PYR-GCK          KGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       KGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155      RGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGN
TH_3810|M.thermoresistible__bu      EDGTG---------------TGIGGRGGNGGSS-----------SGTHPM
MAB_4284c|M.abscessus_ATCC_199      LAGNAGLAGNAGLAG----NAGLAGNAGLAGNAG--------LAGNAGLA
MLBr_01183|M.leprae_Br4923          LEGLS--------------AATVASNAAAAQLT-----------TEIAPP
MAV_4827|M.avium_104                LAVVGISAVLALEIALAIGIRTTGTVALQPTPN-------QHLIVPTEQA
                                        .                  .  .                       

Rv1803c|M.tuberculosis_H37Rv        GGSG------------GVGGSGGDGG------NGGWLFGSGA--------
Mb1831c|M.bovis_AF2122/97           GGSG------------GVGGSGGDGG------NGGWLFGSGA--------
MMAR_3008|M.marinum_M               GGSG------------GNGGSAGDGG------AGGLVLGNGG--------
MUL_2250|M.ulcerans_Agy99           GGSG------------GNGGSAGDGG------AGGLVLGNGG--------
Mflv_5091|M.gilvum_PYR-GCK          GGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG--------
Mvan_1264|M.vanbaalenii_PYR-1       GGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG--------
MSMEG_0868|M.smegmatis_MC2_155      GGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATV
TH_3810|M.thermoresistible__bu      AEDG-------------EHVKALDGR-------PGLDGGNGS--------
MAB_4284c|M.abscessus_ATCC_199      GNAG-------------LAGNAGLAG-------NAAVAGNAA--------
MLBr_01183|M.leprae_Br4923          AADD-------------VSILLAH-----------FFSGHGR--------
MAV_4827|M.avium_104                PAPP------------PVQASAPQPK----ISVPEPVAAPKP--------
                                                                          .           

Rv1803c|M.tuberculosis_H37Rv        ---------SGGNGGQGGDAGTNGFAG-----------------------
Mb1831c|M.bovis_AF2122/97           ---------SGGNGGQGGDAGTNGFAG-----------------------
MMAR_3008|M.marinum_M               ---------AGGNGGQGGDAGANGFAG-----------------------
MUL_2250|M.ulcerans_Agy99           ---------AGGNGGQGGDAGANGFAG-----------------------
Mflv_5091|M.gilvum_PYR-GCK          ---------TGGTGGQGG-LGGGGGTG-----------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---------TGGTGGQGG-LGGVGGTG-----------------------
MSMEG_0868|M.smegmatis_MC2_155      IGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATD
TH_3810|M.thermoresistible__bu      ---------HGGNGGHGG---RGGFLG-----------------------
MAB_4284c|M.abscessus_ATCC_199      ---------VAGNAAVAGNAAVGGVLN----------------------T
MLBr_01183|M.leprae_Br4923          ---------QYQAHASQGATNHQDLIQ-----------------------
MAV_4827|M.avium_104                ------LSPPVAAPLPAAPPPAAPPLP-----------------------
                                                     .                                

Rv1803c|M.tuberculosis_H37Rv        -FGGSAGGGGWVGAVNFGPISVQG-------FGLFGHGGDG---GNGGDV
Mb1831c|M.bovis_AF2122/97           -FGGSAGGGGWVGAVNFGPISVQG-------FGLFGHGGDG---GNGGDV
MMAR_3008|M.marinum_M               -FGGLGGEGGWVGNITLGPIGVDG-------VGLIGHGGDG---GNAGDV
MUL_2250|M.ulcerans_Agy99           -FGGLGGEGGWVGNITLGPIGVDG-------VGLIGHGGDG---GNAGDV
Mflv_5091|M.gilvum_PYR-GCK          GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFG
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFG
MSMEG_0868|M.smegmatis_MC2_155      GHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNG
TH_3810|M.thermoresistible__bu      -IGGSGGWGGHGGNG--GDTDADG-----------GNGGDG---GNGGSA
MAB_4284c|M.abscessus_ATCC_199      GVSGAIGGSSHVGGAINESLGGSG------SVGGSTAVGGGAHTGVGGGV
MLBr_01183|M.leprae_Br4923          --SLLTSSSAYAGTETANHDSL----------------------------
MAV_4827|M.avium_104                EAPPIPAAPPVVPVPVVVPPVPVP-------VPVRIPVPDPVSPPQLLAP
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        GAGSLSIQFG------ASGGDGGQGG----VLYGNGGNGG----NAGSGG
Mb1831c|M.bovis_AF2122/97           GAGSLSIQFG------ASGGDGGQGG----VLYGNGGNGG----NAGSGG
MMAR_3008|M.marinum_M               GAGSLSVQFG------ETGGSGGQGG----LLYGNGGNGG----NAGSGG
MUL_2250|M.ulcerans_Agy99           GAGSLSVQFG------ETGGSGGQGG----LLYGNGGNGG----NAGSGG
Mflv_5091|M.gilvum_PYR-GCK          GSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAG
Mvan_1264|M.vanbaalenii_PYR-1       GVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAG
MSMEG_0868|M.smegmatis_MC2_155      GDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGS
TH_3810|M.thermoresistible__bu      GRG-------------GTGGLRGVFG-------INGGNGR-----AGLGG
MAB_4284c|M.abscessus_ATCC_199      STGVGVGSHVGGGISESLGGSGSVGG-----STAVGGGAH-----TGVGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PRLSVPQPVQPPVRVPQPPSPPQVGG-------TVPQSPPQHQTPPGEGT
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        GTGFEGSAGQ-GGAAILIGNGGAGGNG-------------ATGGTGVGNI
Mb1831c|M.bovis_AF2122/97           GTGFEGSAGQ-GGAAILIGNGGAGGNG-------------ATGGTGVGNI
MMAR_3008|M.marinum_M               TSGFEGVAGQ-GGAAMLIGNGGAGGNG-------------ATGGTGFGNV
MUL_2250|M.ulcerans_Agy99           TSGFEGVAGQ-GGAAMLIGNGGAGGNG-------------ATGGTGFGNV
Mflv_5091|M.gilvum_PYR-GCK          KAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGA
Mvan_1264|M.vanbaalenii_PYR-1       TAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGS
MSMEG_0868|M.smegmatis_MC2_155      TLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGD
TH_3810|M.thermoresistible__bu      RGXXX--XGGGVGAAVRSGNGVFSGGG-------------GTPSAGFGVP
MAB_4284c|M.abscessus_ATCC_199      GVSTGVGVGSHVGGGISESLGGSGSVG-------------GSTAVGGGAH
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PPKPDGPGNYGGGHVPTPGAGGSGGSG-----------GGHVPTPGAGGS
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        IQEAGGDGSDGGAGG-----------------SGGLLFGSGGAGGIGGAG
Mb1831c|M.bovis_AF2122/97           IQEAGGDGSDGGAGG-----------------SGGLLFGSGGAGGIGGAG
MMAR_3008|M.marinum_M               LQESGGAGSDGGIGG-----------------SGGLLFGNGGAGGNAGDG
MUL_2250|M.ulcerans_Agy99           LQESGGAGSDGGIGG-----------------SGGLLFGNGGAGGNAGDG
Mflv_5091|M.gilvum_PYR-GCK          TGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAG
Mvan_1264|M.vanbaalenii_PYR-1       AGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAG
MSMEG_0868|M.smegmatis_MC2_155      GGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADG
TH_3810|M.thermoresistible__bu      TTIQFPAG-------------------------------SCTSRAVSREG
MAB_4284c|M.abscessus_ATCC_199      TGVGGGVNTGVGVGS---------------HVGGGISESLGGSGSVGGST
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GGSGGGHVPTPGTGG-----------------------PGGTGGSGGGHV
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        GVGGSGNDGGNG----------GDGGQGGASGLGIGNGGPGGSGG-----
Mb1831c|M.bovis_AF2122/97           GVGGSGNDGGNG----------GDGGQGGASGLGIGNGGPGGSGG-----
MMAR_3008|M.marinum_M               GVGGTGFDGGDG----------GVGGQGGSSGLLFGNGGDGGDGG-----
MUL_2250|M.ulcerans_Agy99           GVGGTGFDGGDG----------GVGGQGGSSGLLFGNGGDGGDGG-----
Mflv_5091|M.gilvum_PYR-GCK          KAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-----
Mvan_1264|M.vanbaalenii_PYR-1       KAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-----
MSMEG_0868|M.smegmatis_MC2_155      WVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVW
TH_3810|M.thermoresistible__bu      IMPSSRAASARA--------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AVGGGAHTSAIN---------DALGGSGSVGGSTAVGGGAHTSAIN----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PTPGAGTPGGSG------------GGHLPFPGAGSTPGGSGGGHLP----
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        ------TGGAGGTGGSAGTGG--------------AGGDGGNAALLIGTG
Mb1831c|M.bovis_AF2122/97           ------TGGAGGTGGSAGTGG--------------AGGDGGNAALLIGTG
MMAR_3008|M.marinum_M               ------AGGAGGTGGSAGTGG--------------AGGNGGNAALLIGTG
MUL_2250|M.ulcerans_Agy99           ------AG---GTGGSAGTGG--------------AGGNGGNAALLIGTG
Mflv_5091|M.gilvum_PYR-GCK          ------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGA
Mvan_1264|M.vanbaalenii_PYR-1       ------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGA
MSMEG_0868|M.smegmatis_MC2_155      KSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------ESMNSSINASHSSSMN-------------ESFGSSMGSHGAAGT
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----TPGAGTPGGGLGGFGGG-------------HAPAPGGGLGGGGGH
                                                                                      

Rv1803c|M.tuberculosis_H37Rv        GDGGDGVPPAPGGQGGKGGLIGLPGQNGQP
Mb1831c|M.bovis_AF2122/97           GDGGDGVPPAPGGQGGKGGLIGLPGQNGQP
MMAR_3008|M.marinum_M               GNGGAGVPPASGGSGGRGGLIGSAGQNG--
MUL_2250|M.ulcerans_Agy99           GNGGAGVPPASGGSGGRGGLIGSAGQNG--
Mflv_5091|M.gilvum_PYR-GCK          G--GAGGSGGSGGSGGSGGSGGAAGDSDD-
Mvan_1264|M.vanbaalenii_PYR-1       G--GAGGSGGSGGSGGAGGSGGAAGDSD--
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGGNGGNGGADGTPGTAGTTGANNP-
TH_3810|M.thermoresistible__bu      -----GAACASSTSRSRRSFCCSRA-----
MAB_4284c|M.abscessus_ATCC_199      GFEAQGHAQGHASETAHTTLPGAEHH----
MLBr_01183|M.leprae_Br4923          ------------------------------
MAV_4827|M.avium_104                APAPGGGLGGFGGGHSGGGLGGLGGGHK--