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MSYLIAAPEMVAAAATDLASVGSSISAANAAAAAPTMSVLAAGADEVSAVVAALFDAHAQAYQSLSAQAA LFHEQFVQALNAGAGSYALAEAASVSPLQDALNLINAPTQALFGRPLIGNGADGAPGTGQSGGNGGFLYG NGGNGGSGANNQGGGNGGSAGLWGNGGAGGAGGDSTVAGVNGFNGGAGGSGGLLWGNGGAGGAGGNGGGA PLAGFVGTSGGNGGNGGGAGLLYGYGGAGGAGGTGGVAPPTGVGQTILSAGGVGGTGGAGGGGAALIGFG GAGGTGGTGGLSDTTTETIGGYGGMGGLGGQSGVLFGTPGAGGAGGAGGAGVGTFASPGGHGGSGGDAGA IGLFGNGAAGGDGGIGGDGASGGNDGGNGGVGGLGGVGGPGGWIFGTGGAGGNGGLGGSGGTGVVTNGFA GSGGFGGAGGDAQFLGFGGTGGSGGGIGAGETAAVPLTTQPVGGTGGNGGRAGLFFGVGGTGGNGGATST NGALYATGGNGGDGGLIFGNGGTGGNGGAGGGTSVGAGGQGGAASAFFGNGGAGGDGGAGGQGAGGAGGS GALFFGNGGAGGNGAPGGTGVGGTGGSAVLIGNGGDGGDGTGGAAGGAGGSGGFIFGQNGSNGLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2645 | - | - | 100% (625) | PE-PGRS family protein |
| M. marinum M | MMAR_5044 | - | e-176 | 54.74% (665) | PE-PGRS family protein |
| M. marinum M | MMAR_1208 | - | e-171 | 49.05% (736) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1797 | PE_PGRS31 | 0.0 | 74.04% (624) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-113 | 46.88% (576) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1768 | PE_PGRS31 | 0.0 | 73.72% (624) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 4e-11 | 34.78% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 9e-44 | 33.88% (428) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 4e-23 | 41.67% (204) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 4e-94 | 40.97% (637) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-39 | 35.62% (320) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1339 | - | 1e-164 | 50.30% (674) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-110 | 45.86% (580) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1797|M.bovis_AF2122/97 --------------------------------------------------
Rv1768|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2645|M.marinum_M --------------------------------------------------
MUL_1339|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1797|M.bovis_AF2122/97 --------------------------------------------------
Rv1768|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2645|M.marinum_M --------------------------------------------------
MUL_1339|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1797|M.bovis_AF2122/97 ------------------------------------------MSYLVVVP
Rv1768|M.tuberculosis_H37Rv ------------------------------------------MSYLVVVP
MMAR_2645|M.marinum_M ------------------------------------------MSYLIAAP
MUL_1339|M.ulcerans_Agy99 ------------------------------------------MSYVIAAP
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1797|M.bovis_AF2122/97 ----------------------------------------ELVAAAATDL
Rv1768|M.tuberculosis_H37Rv ----------------------------------------ELVAAAATDL
MMAR_2645|M.marinum_M ----------------------------------------EMVAAAATDL
MUL_1339|M.ulcerans_Agy99 ----------------------------------------EEFASAARNL
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------VEAASYVADPEAAL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1797|M.bovis_AF2122/97 AN----------------------IGSSIS-----------AANAAAAAP
Rv1768|M.tuberculosis_H37Rv AN----------------------IGSSIS-----------AANAAAAAP
MMAR_2645|M.marinum_M AS----------------------VGSSIS-----------AANAAAAAP
MUL_1339|M.ulcerans_Agy99 AN----------------------IGVTIN-----------AANANAILA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AN----------------------AGLSAVS----------AAQVGAVMP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS
Mb1797|M.bovis_AF2122/97 TT-------ALVAAGGDEVSAAIAALFGAHARAYQALSAQAAMFHEQFVR
Rv1768|M.tuberculosis_H37Rv TT-------ALVAAGGDEVSAAIAALFGAHARAYQALSAQAAMFHEQFVR
MMAR_2645|M.marinum_M TM-------SVLAAGADEVSAVVAALFDAHAQAYQSLSAQAALFHEQFVQ
MUL_1339|M.ulcerans_Agy99 TT-------EVIQPGADAVSAAITALINSHGLGYQSISQQTTAFHDRFVQ
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
Mb1797|M.bovis_AF2122/97 ALAAGGNSYAVAEAATAQSVQQDLLNLINAPTQALLG-RPLIGNGANGLP
Rv1768|M.tuberculosis_H37Rv ALAAGGNSYAVAEAATAQSVQQDLLNLINAPTQALLG-RPLIGNGANGLP
MMAR_2645|M.marinum_M ALNAGAGSYALAEAASVS-PLQDALNLINAPTQALFG-RPLIGNGADGAP
MUL_1339|M.ulcerans_Agy99 TVNAAAASYTTTDLTAAS-LLKSMPTAVNAPAQALFG-RPLIGNGSNGTP
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 PRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
Mb1797|M.bovis_AF2122/97 GTGQNGGDGGILYGNGGNGGSGGVNQAGGNGGNAG--------------L
Rv1768|M.tuberculosis_H37Rv GTGQNGGDGGILYGNGGNGGSGGVNQAGGNGGNAG--------------L
MMAR_2645|M.marinum_M GTGQSGGNGGFLYGNGGNGGSGANNQGGGNGGSAG--------------L
MUL_1339|M.ulcerans_Agy99 GTGAPGGDGGILFGSGGAGGSGAGGQDGGAGGRAG--------------L
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTG--------------L
MAB_4284c|M.abscessus_ATCC_199 FGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNG---------DVRDSN
MLBr_01183|M.leprae_Br4923 ---------MPLFLN-----AEPQALTAAANTLEG---------------
MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGS-----------IPDV
.
Mb1797|M.bovis_AF2122/97 WGNGGSGGAGGNATTAG--------------------RNGFNGGAGGSG-
Rv1768|M.tuberculosis_H37Rv WGNGGSGGAGGNATTAG--------------------RNGFNGGAGGSG-
MMAR_2645|M.marinum_M WGNGGAGGAGGDSTVAG--------------------VNGFNGGAGGSG-
MUL_1339|M.ulcerans_Agy99 FGNGGAGGAGGTGQTQGGAGGAGGLFFGNGGAGGPGGSGGLNGGAGGAGG
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG-----------------NAGLPGKAGDAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG-----------------NAGLPGAAGAAGGAG-
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQS---------------TAAGPGKGGGGGGGGG
TH_3810|M.thermoresistible__bu FSKLSRGGDGGDGGLGG--------------------NGGHGGGTGIIS-
MAB_4284c|M.abscessus_ATCC_199 IINADHGSNVGVDQSQTRVG----------------GDYTNVSGHGSADI
MLBr_01183|M.leprae_Br4923 LSAATVASNAAAAQLTT---------------------EIAPPAADDVS-
MAV_4827|M.avium_104 YKQQIRAESYGDAAGQLS-----------------AMVAGLEKLESLPGG
. . . .
Mb1797|M.bovis_AF2122/97 --GLLWGNG---------GAGGAGGH--------GGPAPLVG-------G
Rv1768|M.tuberculosis_H37Rv --GLLWGNG---------GAGGAGGN--------GGPAPLVG-------G
MMAR_2645|M.marinum_M --GLLWGNG---------GAGGAGGN--------GGGAPLAG-------F
MUL_1339|M.ulcerans_Agy99 VGGLLFGAG---------GAGGAGGSGTSGIGGLGGDGGSAG-------A
Mflv_5091|M.gilvum_PYR-GCK ---AVGAAG-------AAGTVGTAGATGGTGTGANGGAGGVG-----GVG
Mvan_1264|M.vanbaalenii_PYR-1 ---AIGTAG-------VAGAAGTAGATGGTGVGGNGGAGQAG-----GIG
MSMEG_0868|M.smegmatis_MC2_155 GAILIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTG
TH_3810|M.thermoresistible__bu ---LLSLAG----------NGGNGGN--------GYRTTDNN-------A
MAB_4284c|M.abscessus_ATCC_199 DKSVTVVDD---------HSQRNTTNINDSFNTDRSTNIGSG-------N
MLBr_01183|M.leprae_Br4923 ---ILLAHF----------FSGHGRQ--------YQAHASQG--------
MAV_4827|M.avium_104 --LLLVGSG---------VDVAPLKQVLQTTTFLDVSVAEEP-------E
Mb1797|M.bovis_AF2122/97 VGTTGGAGGNGGGAGLFYGFGGAGGNG-------------------GMGG
Rv1768|M.tuberculosis_H37Rv VGTTGGAGGNGGGAGLFYGFGGAGGNG-------------------GMGG
MMAR_2645|M.marinum_M VGTSGGNGGNGGGAGLLYGYGGAGGAG-------------------GTGG
MUL_1339|M.ulcerans_Agy99 LSISAGGAGGNGGTGLS-GFGGAGGAGG-----------NAGLYGHGGGG
Mflv_5091|M.gilvum_PYR-GCK GTGAAGAAGGAGGLGETGTTGGAGGVG--------------------GQG
Mvan_1264|M.vanbaalenii_PYR-1 GTGAAGAAGQAGTAGETGVTGGVGGIG--------------------GQG
MSMEG_0868|M.smegmatis_MC2_155 STAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDG
TH_3810|M.thermoresistible__bu LDGGHGGNGGNVGFFSLFNLGGAGGWG--------------------GSG
MAB_4284c|M.abscessus_ATCC_199 TTNTEIGSHNQANIGTSTSAGGSAAVG-------------------GNAG
MLBr_01183|M.leprae_Br4923 --ATNHQDLIQSLLTSSSAYAGTETAN--------------------HDS
MAV_4827|M.avium_104 TALARGAALAAANAPLFASSTAALAYAQ-----------------DPGTG
. .
Mb1797|M.bovis_AF2122/97 VAPSTGPSMGILPAGG----------VGGPGG-------SGGAS------
Rv1768|M.tuberculosis_H37Rv VAPSTGPSMGILPAGG----------VGGPGG-------SGGAS------
MMAR_2645|M.marinum_M VAPPTGVGQTILSAGG----------VGGTGG-------AGGGG------
MUL_1339|M.ulcerans_Agy99 GAGGTGTGMGVDNDG-----------IGGAGG-------AGGAG------
Mflv_5091|M.gilvum_PYR-GCK TAGGTGGVGGIGGAG----------STGAVGG-------VGGKG----IQ
Mvan_1264|M.vanbaalenii_PYR-1 TEGGTGGVGGVGGVG----------ATGGAGG-------VGGKG----IQ
MSMEG_0868|M.smegmatis_MC2_155 IDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQ
TH_3810|M.thermoresistible__bu VDG-----------------------VDVVGG------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGN----------AGLAGN-------AGLAG------
MLBr_01183|M.leprae_Br4923 L-------------------------------------------------
MAV_4827|M.avium_104 AVDQYSLPDYLYVPVD-----------PEPGD------------------
Mb1797|M.bovis_AF2122/97 ----------------ALAFGSGGVGGAGGLGG-----------------
Rv1768|M.tuberculosis_H37Rv ----------------ALAFGSGGVGGAGGLGG-----------------
MMAR_2645|M.marinum_M ----------------AALIGFGGAGGTGGTGG-----------------
MUL_1339|M.ulcerans_Agy99 ----------------GWLIGTGGTGGTGGFGD-----------------
Mflv_5091|M.gilvum_PYR-GCK GGQG-------------LQGGKGGDGGAGGKGGDADSMGS----------
Mvan_1264|M.vanbaalenii_PYR-1 GGQG-------------LQGGQGGDGGTGGTGGDATSMGE----------
MSMEG_0868|M.smegmatis_MC2_155 AGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNT
TH_3810|M.thermoresistible__bu ----------------------NPDGGTPGAHG-----------------
MAB_4284c|M.abscessus_ATCC_199 ------------------NAGLAGNAGLAGNAG-----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------DELAYSAVGEEDAESPTVVIEKLFLP-------
Mb1797|M.bovis_AF2122/97 ---------PTDGTVQGVGGFGGQ---------------------GGNGG
Rv1768|M.tuberculosis_H37Rv ---------PTDGTVQGVGGFGGQ---------------------GGNGG
MMAR_2645|M.marinum_M ---------LSDTTTETIGGYGGM---------------------GGLGG
MUL_1339|M.ulcerans_Agy99 ---------GPLGGQGGDGGNAGL---------------------FGVGG
Mflv_5091|M.gilvum_PYR-GCK --------AGATGGKGGNGGNGGRGGLFG---------------KGGNAG
Mvan_1264|M.vanbaalenii_PYR-1 --------AGATGGKGGNGGNGGRGSLFG---------------RGGNAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGG
TH_3810|M.thermoresistible__bu -------------ESHTPGVYTDR---------------------QGEDG
MAB_4284c|M.abscessus_ATCC_199 --------LAGNAGLAGNAGLAGN---------------------AGLAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------EDSEPRRRPVLLVGSG--------------------LAVVG
Mb1797|M.bovis_AF2122/97 QSGL---------------------LFGNAGAGGAGAAGG--AGTGDTES
Rv1768|M.tuberculosis_H37Rv QSGL---------------------LFGNAGAGGAGAAGG--AGTGDTES
MMAR_2645|M.marinum_M QSGV---------------------LFGTPGAGGAGGAGG--AGVGTFAS
MUL_1339|M.ulcerans_Agy99 DGGLG-----------------GTGFFGAGGAGGAAGNAGLISGTGDVGG
Mflv_5091|M.gilvum_PYR-GCK NGAD----------------------GGTGGAGGAGGTGG-TGGAGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 NGGN----------------------GGTGGNGGNGGTGG-TGGNGGTGG
MSMEG_0868|M.smegmatis_MC2_155 NGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGA
TH_3810|M.thermoresistible__bu EDGTG---------------------TGIGGRGGNGGSSS----------
MAB_4284c|M.abscessus_ATCC_199 NAGLAG-------------------NAGLAGNAGLAGNAGLAGNAGLAGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ISAVLA--------------------LEIALAIGIRTTGTVALQPTPNQH
Mb1797|M.bovis_AF2122/97 FG--------------------GHGGAGGDGGAVGLIGNGGGGGNGGAG-
Rv1768|M.tuberculosis_H37Rv FG--------------------GHGGAGGDGGAVGLIGNGG------AG-
MMAR_2645|M.marinum_M PG--------------------GHGGSGGDAGAIGLFGNGAAGGDGGIG-
MUL_1339|M.ulcerans_Agy99 QGGV---------------GGFGEGGAGGDGGGAGLIGNGG---------
Mflv_5091|M.gilvum_PYR-GCK -----------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-
Mvan_1264|M.vanbaalenii_PYR-1 -----------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-
MSMEG_0868|M.smegmatis_MC2_155 GASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE
TH_3810|M.thermoresistible__bu ----------------------GTHPMAEDGEHVKAL-------------
MAB_4284c|M.abscessus_ATCC_199 AG---------------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAAVA-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LIVP------------------TEQAPAPPPVQASAPQPKISVPEPVAAP
Mb1797|M.bovis_AF2122/97 GTGSPGAV--VGGNGGVGGLGGAGSPG------GLLYGTGGAGGNG----
Rv1768|M.tuberculosis_H37Rv GTGSPGAV--VGGNGGVGGLGGAGSPG------GLLYGTGGAGGNG----
MMAR_2645|M.marinum_M GDGASGGN--DGGNGGVGGLGGVGGPG------GWIFGTGGAGGNG----
MUL_1339|M.ulcerans_Agy99 -SGGTGGN--AVGNSGVGGHGGAGGRG------GRLYGNGGVGGNGGF--
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG----
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG----
MSMEG_0868|M.smegmatis_MC2_155 GEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYV
TH_3810|M.thermoresistible__bu -DGRPGLD---GGNGSHGGNGGHGGRG----------GFLGIGGSG----
MAB_4284c|M.abscessus_ATCC_199 GNAAVAGNAAVAGNAAVGGVLNTGVSG-------AIGGSSHVGGAIN---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 KPLSPPVAAPLPAAPPPAAPPLPEAPP--------IPAAPPVVPVPVVVP
Mb1797|M.bovis_AF2122/97 --------GPGGDGGTG------------ATVGFAGSGG----FGGAGGI
Rv1768|M.tuberculosis_H37Rv --------GPGGDGGTG------------ATVGFAGSGG----FGGAGGI
MMAR_2645|M.marinum_M --------GLGGSGGTGV-----------VTNGFAGSGG----FGGAGGD
MUL_1339|M.ulcerans_Agy99 -SGPITAGGAGGTGGTG------------GSAGLPGDGG----AGGAGGA
Mflv_5091|M.gilvum_PYR-GCK -----GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQ
Mvan_1264|M.vanbaalenii_PYR-1 -----GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQ
MSMEG_0868|M.smegmatis_MC2_155 DPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGK
TH_3810|M.thermoresistible__bu --------GWGGHGGNG--------------GDTDADGG----NGGDGGN
MAB_4284c|M.abscessus_ATCC_199 -------ESLGGSGSVG--------------GSTAVGGG--AHTGVGGGV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PVPVPVPVRIPVPDPVS-------------PPQLLAPPRLSVPQPVQPPV
Mb1797|M.bovis_AF2122/97 AQLFG-----------------TGGMGGSGGGIGAGTTTV----------
Rv1768|M.tuberculosis_H37Rv AQLFG-----------------TGGMGGSGGGIGAGTTTV----------
MMAR_2645|M.marinum_M AQFLG-----------------FGGTGGSGGGIGAGETAA----------
MUL_1339|M.ulcerans_Agy99 SGFAGGG---------------TGGIGGTGG-LPFGAAGD----------
Mflv_5091|M.gilvum_PYR-GCK GGQGG-----------------TGGTGGQGG-LGGGGGTG----------
Mvan_1264|M.vanbaalenii_PYR-1 GGQGG-----------------TGGTGGQGG-LGGVGGTG----------
MSMEG_0868|M.smegmatis_MC2_155 GGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNV
TH_3810|M.thermoresistible__bu GGSAG-----------------RGGTGGLRGVFGINGGNG----------
MAB_4284c|M.abscessus_ATCC_199 STGVGVG---------------SHVGGGISESLGGSGSVG----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 RVPQPPS---------------PPQVGGTVPQSPPQHQTP----------
Mb1797|M.bovis_AF2122/97 -------------VPPDVAPVGGTGGNGGRAG----------LLLGVGGM
Rv1768|M.tuberculosis_H37Rv -------------VPPDVAPVGGTGGNGGRAG----------LLLGVGGM
MMAR_2645|M.marinum_M -------------VPLTTQPVGGTGGNGGRAG----------LFFGVGGT
MUL_1339|M.ulcerans_Agy99 -------------GGNGGFGAGGRGGSGGAGGD--------AWLFGSGGS
Mflv_5091|M.gilvum_PYR-GCK -------------GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGA
Mvan_1264|M.vanbaalenii_PYR-1 -------------GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGA
MSMEG_0868|M.smegmatis_MC2_155 VQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGN
TH_3810|M.thermoresistible__bu -----------------------RAGLGGRGX--------------XXXG
MAB_4284c|M.abscessus_ATCC_199 --------------GSTAVGGGAHTGVGGGVSTG----------VGVGSH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------PGEGTPPKPDGPGNYGG-------------GHVPT
Mb1797|M.bovis_AF2122/97 GGNGGATSVG-----------GTLYAAGGNGGDG----------------
Rv1768|M.tuberculosis_H37Rv GGNGGATSVG-----------GTLYAAGGNGGDG----------------
MMAR_2645|M.marinum_M GGNGGATSTN-----------GALYATGGNGGDG----------------
MUL_1339|M.ulcerans_Agy99 GGSGGAGAINDGGSGGAVGNGGRLFGDAGAGGSGGAGGTSFLDTVIVSSN
Mflv_5091|M.gilvum_PYR-GCK GGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG----QAGTAGK
Mvan_1264|M.vanbaalenii_PYR-1 GGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG----QAGVAGK
MSMEG_0868|M.smegmatis_MC2_155 GGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGG--KATGTASQ
TH_3810|M.thermoresistible__bu GGVGAAVRSGN----------GVFSGGGGTPSAG----------------
MAB_4284c|M.abscessus_ATCC_199 VGGGISESLGG---------SGSVGGSTAVGGGAHTGVGG----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PGAGGSGGSG-----------GGHVPTPGAGGSG----------------
Mb1797|M.bovis_AF2122/97 GLVWG-----------NGGTG---GSGGAGGAGSVG------------NG
Rv1768|M.tuberculosis_H37Rv GLVWG-----------NGGTG---GSGGAGGAGSVG------------NG
MMAR_2645|M.marinum_M GLIFG-----------NGGTG---GNGGAGGGTSVG------------AG
MUL_1339|M.ulcerans_Agy99 GGAAG-----------NGGSAGLVGNGGAGGAGGQGGLIVSADDNNGGAG
Mflv_5091|M.gilvum_PYR-GCK GGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQ
Mvan_1264|M.vanbaalenii_PYR-1 GGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQ
MSMEG_0868|M.smegmatis_MC2_155 GGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAA
TH_3810|M.thermoresistible__bu ----------------FGVPTTIQFPAGSCTSRAVS--------------
MAB_4284c|M.abscessus_ATCC_199 GVNTG---------VGVGSHVGGGISESLGGSGSVGG-----------ST
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------GSGGGHVPTPGTGGPGGTG--------------
Mb1797|M.bovis_AF2122/97 GAGGNAALLFGNGGAGGAGGAGG-IGAGG---------------------
Rv1768|M.tuberculosis_H37Rv GAGGNAALLFGNGGAGGAGGAGG-IGAGG---------------------
MMAR_2645|M.marinum_M GQGGAASAFFGNGGAGGDGGAGG-QGAGG---------------------
MUL_1339|M.ulcerans_Agy99 GDGGGAGLLLGAGGAGGQGGLGGNTVDGG---------------------
Mflv_5091|M.gilvum_PYR-GCK GATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGT
Mvan_1264|M.vanbaalenii_PYR-1 GATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGT
MSMEG_0868|M.smegmatis_MC2_155 GTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGH
TH_3810|M.thermoresistible__bu -REGIMPSSRAASARAGAACASSTSRSRR---------------------
MAB_4284c|M.abscessus_ATCC_199 AVGGGAHTSAINDALGGSGSVGGSTAVGG---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GSGGGHVPTPGAGTPGGSGGGHLPFPGAG---------------------
Mb1797|M.bovis_AF2122/97 ----AGGFG-------------AVLFG-----------------------
Rv1768|M.tuberculosis_H37Rv ----AGGFG-------------AVLFG-----------------------
MMAR_2645|M.marinum_M ----AGGSG-------------ALFFG-----------------------
MUL_1339|M.ulcerans_Agy99 ----NGGNGGN-----------AALIG-----------------------
Mflv_5091|M.gilvum_PYR-GCK NGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-
Mvan_1264|M.vanbaalenii_PYR-1 NGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-
MSMEG_0868|M.smegmatis_MC2_155 GGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1797|M.bovis_AF2122/97 -NGGAGGSGA------------PGGIG---AGGNGGNALL--------VG
Rv1768|M.tuberculosis_H37Rv -NGGAGGSGA------------PGGIG---AGGNGGNALL--------VG
MMAR_2645|M.marinum_M -NGGAGGNGA------------PGGTG---VGGTGGSAVL--------IG
MUL_1339|M.ulcerans_Agy99 -DGGSGGAGG------------DGGSGDAGDGGAGGDARL--------VG
Mflv_5091|M.gilvum_PYR-GCK INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE--------GG
Mvan_1264|M.vanbaalenii_PYR-1 INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE--------GG
MSMEG_0868|M.smegmatis_MC2_155 ASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGG
TH_3810|M.thermoresistible__bu ---SFCCSRA----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --GAHTSAIN--------------ESMNSSINASHSSSMN----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --STPGGSGG-------------GHLPTPGAGTPGGGLGGFG------GG
Mb1797|M.bovis_AF2122/97 NGGNGGAG---TGGAA----GGAGGSGG--LLFGQNGMPGP---
Rv1768|M.tuberculosis_H37Rv NGGNGGAG---TGGAA----GGAGGSGG--LLFGQNGMPGP---
MMAR_2645|M.marinum_M NGGDGGDG---TGGAA----GGAGGSGG--FIFGQNGSNGLP--
MUL_1339|M.ulcerans_Agy99 SGGNGGNGGFSATPAA----GGTGDAGG--AVFGSDGVAGLP--
Mflv_5091|M.gilvum_PYR-GCK AGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 AGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 AGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu --------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH---
MLBr_01183|M.leprae_Br4923 --------------------------------------------
MAV_4827|M.avium_104 HAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-