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M. tuberculosis H37Rv Rv1359 (-)

annotation: PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
coordinates: 1530173 - 1530925
length: 250

MFMALRAPMLERMNGLHTDDAPVNWLERRGGRLTSRRRVTLLHAGVEHPMRLWGVQSEAITAAMVLSRKV
SAIIAGHCGVRLVDQGVGDGFVAAFAHASDAVACALELHQAPLSPIVLRIGIHTGEAQLVDERIYAGATM
NLAAELRDLAHGGQTVMSGATEDAVLGRLPMRAWLIGLRPMEGSPEGHNFPQSQRIAQLCHPNLRNTFPP
LRMRIADASGIPYVGRILVNVQVVPHWEGGCAAAGMVLAG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1359--100% (250)PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
M. tuberculosis H37RvRv0386-3e-4652.48% (202) LuxR/UHPA family transcriptional regulator
M. tuberculosis H37RvRv2488c-2e-4348.13% (214) LuxR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1394-1e-14399.60% (250) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_2091-2e-0728.06% (139) putative adenylate/guanylate cyclase
M. leprae Br4923MLBr_01753-6e-2743.26% (178) putative transcriptional regulator
M. abscessus ATCC 19977-----
M. marinum MMMAR_0123-4e-4349.00% (200) LuxR family transcriptional regulator
M. avium 104MAV_5228-3e-0737.35% (83) hydrolase, alpha/beta hydrolase fold family protein
M. smegmatis MC2 155MSMEG_0545-2e-1737.72% (167) transcriptional regulator, LuxR family protein
M. thermoresistible (build 8)TH_1244-6e-0930.94% (139) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_2743-2e-1333.71% (175) LuxR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_5928-7e-4553.11% (177) regulatory protein, LuxR

CLUSTAL 2.0.9 multiple sequence alignment


Rv1359|M.tuberculosis_H37Rv         MFMALRAPMLERMNGLHTDDAPVNWLERRGG------RLTSRRRVTLLHA
Mb1394|M.bovis_AF2122/97            MFMALRAPMLERMNGLHTDDAPVNWLERRGG------RLTSRRRVTLLHA
MMAR_0123|M.marinum_M               ----MLASMSEIDP--RAEAPLVDWSDVDMG------ELLPTGTVTLLLA
Mvan_5928|M.vanbaalenii_PYR-1       -----------------------------MS------ELVPTGTVTLLLA
MLBr_01753|M.leprae_Br4923          --MYSLGEMQKPVP--VGADYLASCLVARLRSTDVPTDLHRGCTVTLFLG
MSMEG_0545|M.smegmatis_MC2_155      --------MT---------------------------EKLSTGTKTLLMA
MUL_2743|M.ulcerans_Agy99           --------------------------------------------MTFLFT
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------VAARPLPLAVAAAPGSPI
MAV_5228|M.avium_104                ------------------------------------------------MP
                                                                                      

Rv1359|M.tuberculosis_H37Rv         GVEHPMRLWGVQSEAITAAMV-LSRKVSAIIAGHCGVRLVDQGVGDGFVA
Mb1394|M.bovis_AF2122/97            GVEHPMRLWGVQSEAITAAMV-LSRKVSAIIAGHCGVRLVDQGVGDGFVA
MMAR_0123|M.marinum_M               DVEGSTRLWQNQPEPMTAAVAHLDSVLATTVATHHGVRPVEQGEGDSFVV
Mvan_5928|M.vanbaalenii_PYR-1       DVQGSTQLWETQPETMTAAVAQLDRTLTDLVSDHDGVRPVEQGEGDSFVV
MLBr_01753|M.leprae_Br4923          DVEGLAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLA
MSMEG_0545|M.smegmatis_MC2_155      RVDRAEELWQTELDQTIAAIPWLRASMAHLIALNDGT--LQRDASDSFVA
MUL_2743|M.ulcerans_Agy99           DVEGSTRLWESDPDRMRAALAAHDAVLTRTIQTHRGWLFKHTG--DGVCA
Mflv_2091|M.gilvum_PYR-GCK          ------------MLILVCVLAVLAAGLGIALAVQTRRLTSARQEAEELRH
TH_1244|M.thermoresistible__bu      PRRVGQDGAVTQIAIVVVALAGLALAEAVALAVLWGRLRRERRAADELRR
MAV_5228|M.avium_104                GFSGTPRTRYASCGDTDIAYQVLGDGPIDLVLLPGPSIPIDSVDAEPSMY
                                                      .           :                   

Rv1359|M.tuberculosis_H37Rv         AFAHASDAVACALELHQAPLSPIVLRIGIHTG--EAQLVDER---IYAGA
Mb1394|M.bovis_AF2122/97            AFAHASDAVACALELHQAPLSPIVLRIGIHTG--EAQLVDER---IYAGA
MMAR_0123|M.marinum_M               AFASAREAIACALDLQRSPLGPIRLRIGVHTG--DIQLRDPNDPTNYIGP
Mvan_5928|M.vanbaalenii_PYR-1       AFTRASDAVACALALQRAPLAPIRLRIGVHTG--EVRLRDEG---NYVGP
MLBr_01753|M.leprae_Br4923          TFARASDATACALDLQLAPIVPVRFRIALHTG--EVQISNDD--VNNVVF
MSMEG_0545|M.smegmatis_MC2_155      AFDRASDAVMCALDLQLAPLEPFALCIGVHAV--EHTDSADS--------
MUL_2743|M.ulcerans_Agy99           AFASPRSAVDAAVDAQRALELPVRMGLATGEA--EPHDADYFG------A
Mflv_2091|M.gilvum_PYR-GCK          RLDTRQLLVSGGTKAVKTVWQTANILRKDGFG--AAVRSSIEELADWAEV
TH_1244|M.thermoresistible__bu      RLDTRTTLMAGGREAVRTVWQTANILRTDGLG--AAARSSIEDLADWAEV
MAV_5228|M.avium_104                RFHRRLAAFARVIRLDQRGIGLSSRVPSVDVIGPEFWARDVVSVMDAVGC
                                     :                                                

Rv1359|M.tuberculosis_H37Rv         TMNLAAELRDLAHGGQTVMSGATEDAVLGRLPMRAWLIGLRPMEGSPEGH
Mb1394|M.bovis_AF2122/97            TMNLAAELRDLAHGGQTVMSGATEDAVLGRLPMRAWLIGLRPMEGSPERH
MMAR_0123|M.marinum_M               TINRTARIRELAHGGQTVISGATQLLVVDQLPDGAWLADL----GLHPLR
Mvan_5928|M.vanbaalenii_PYR-1       TINRTARLRELAHGGQTVLSGTTSDLVADLLPDGGWLSDL----GTHRLR
MLBr_01753|M.leprae_Br4923          MMVQAAGLLDLACGGQTVLSSITGDLVVDGLPADTWLVDL----GSHLLR
MSMEG_0545|M.smegmatis_MC2_155      --DGAARLRDIARGGQTLISAAAAALVSARMPAHAALTPL---------R
MUL_2743|M.ulcerans_Agy99           VLNRAARVMATGHGGQILLTDSTANLISG-----VDLLDLG----SRRLR
Mflv_2091|M.gilvum_PYR-GCK          ERPDLARLSLNGRLTIMFSDIEESTALNERIGDRAFVRLIG---------
TH_1244|M.thermoresistible__bu      ERPDLARLAANGKVVILFSDIEGSTALNNRIGDRAWVRLID---------
MAV_5228|M.avium_104                ERATVVAPSFTSMTGLVLAADYPDRVSSLVIINGAARTVYAPDYPMGARI
                                         .     .     .                                

Rv1359|M.tuberculosis_H37Rv         NFPQSQRIAQLCHPNLRNTFPPLRMRIADASG------IPYVG-------
Mb1394|M.bovis_AF2122/97            NFPQSQRIAQLCHPNLRNTFPPLRMRIADASG------IPYVG-------
MMAR_0123|M.marinum_M               DLPRPERVMQLCHSGLQNDFPPLRTTKSIAVHRMPARLTRFVGRIAQMAD
Mvan_5928|M.vanbaalenii_PYR-1       DLPRPERVVQLCHADLSNEFPPLRAREEIGVQRLPAQLTSFVGRVDDMAQ
MLBr_01753|M.leprae_Br4923          DLARPVRVMQLCHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKE
MSMEG_0545|M.smegmatis_MC2_155      DRVRHEPVYQLNHPGLR---------------------------------
MUL_2743|M.ulcerans_Agy99           DLPAPVRVFQVRAPGLRTDFPALRAPDTSPGN-LRPALTSFVARAAEIGQ
Mflv_2091|M.gilvum_PYR-GCK          RHDKSVRKFVDKHEGHVVKSQGDG--------------------------
TH_1244|M.thermoresistible__bu      RHSRLVRRFVKKHDGYVIKSQGDG--------------------------
MAV_5228|M.avium_104                ETLDPYTTVAVDPDAVDQGFDMLG--------------------------
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               VRSLLADNRLVTLTGAGGAGKTRLAVEIAASAVDEFGDGLWYVDLAPVSH
Mvan_5928|M.vanbaalenii_PYR-1       VRGLMDANRLVTLTGAGGVGKTRLATQVAVAVVEGYPGGVWYVDLAPITD
MLBr_01753|M.leprae_Br4923          LQELLTEKRLLTLVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTD
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           VQTALQVHRLVTLTGVGGVGKTRLALEVATRVADEFPDGVWLFELAAVSD
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                --------------------------------------------------
                                                                                      

Rv1359|M.tuberculosis_H37Rv         ---------------------------------RILVNVQVVPHWEGGCA
Mb1394|M.bovis_AF2122/97            ---------------------------------RILVNVQVVPHWEGGCA
MMAR_0123|M.marinum_M               AEAVPVTVARALGLSDQPGRSTVDALARFIGEHQVLVVLDNCEHLLDATA
Mvan_5928|M.vanbaalenii_PYR-1       PALVAITVARALGLPDQPGRSTVDTIVRFIADRRMLVVLDNCEHLLDACA
MLBr_01753|M.leprae_Br4923          HDIFPITVL--------------DNLRRCIGDRRMLMVLDNCEYLLDVCA
MSMEG_0545|M.smegmatis_MC2_155      ------------------------------------TEADEVPHLPYGRV
MUL_2743|M.ulcerans_Agy99           PAAVPDAVAAVLGITQQAGKTVTQSVATALERRVRLLVFDNCEHVRDAAA
Mflv_2091|M.gilvum_PYR-GCK          ----------------------------------FMVAFAKPEQAVRCGL
TH_1244|M.thermoresistible__bu      ----------------------------------FMVAFARPEQAVRCSV
MAV_5228|M.avium_104                ----------------------------------LIAPSVAGDAAFRSWW
                                                                                      

Rv1359|M.tuberculosis_H37Rv         AAGMVLAG------------------------------------------
Mb1394|M.bovis_AF2122/97            AAGMVLAG------------------------------------------
MMAR_0123|M.marinum_M               ALLLELTGRCPAVRLLATSREPLGVPGEVTFLVP----SLSVT-EATELF
Mvan_5928|M.vanbaalenii_PYR-1       TLIDALLGACPALAMLATSREPIAVAGEQTWRVP----PLALDDDAIELF
MLBr_01753|M.leprae_Br4923          NVMTTLLGACPSLTILATSREPIGVAGEVIWRVS----MLSPADEAVELF
MSMEG_0545|M.smegmatis_MC2_155      VR------------------------------------------------
MUL_2743|M.ulcerans_Agy99           DLIEAILAGSTTVRILATSRERLEVPDEQLWSVPSLDVGGGVVSAAGTLF
Mflv_2091|M.gilvum_PYR-GCK          DIQHSLARRPNDIRVRMGVHTGKSVL------------------RGDDVF
TH_1244|M.thermoresistible__bu      ELQRALRKRPDRIRVRIGIHLGRSVR------------------RGDDLF
MAV_5228|M.avium_104                DAAGNRAASPSMARAMILSIRHADVRDRLARITTP----TLILHRTDCVF
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               TDRARRVRPDFAVTDDNTTAVT-EICNRLDCMPLAIELAAARVRALSIDE
Mvan_5928|M.vanbaalenii_PYR-1       TDRARRARPDFIISADDAAAVS-EICHRLDGMPLAIELAAARVRALSLTE
MLBr_01753|M.leprae_Br4923          TERAALVQPGFSVTDGNRQIVT-EICQRLDGMPLAIELAAARIRTLSLTE
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           VERAQSVAPGFAPTDAQDAAAIGEICRRLDGIPLAIELAASRMASMTPIE
Mflv_2091|M.gilvum_PYR-GCK          GRNVAMAARVAAAADGGEILVSSAVHRALA------DCEDLAFD------
TH_1244|M.thermoresistible__bu      GRNVALAARVAGAAEGGEVLVSQAVRDALN------SAGDAGSDEVAGFD
MAV_5228|M.avium_104                TS--VDHGRYLAEHIAGSRFVSLPGEDTLYWVGDTGPMLDEIEEFITGVR
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               IRTGLHDRFRLLTGGARTVVRRQQTLRASVDWSHALLTEPERVLFRRIAV
Mvan_5928|M.vanbaalenii_PYR-1       IVDGLHDRFRLLTGGSRTAVRRQQTLRASVDWSHGLLTDPERVLFRRLAV
MLBr_01753|M.leprae_Br4923          IADGLDDRFRLLTGGARTAVRRQQTLRASMDWSYALLTESERALFRRLSA
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           VRDRLDHRFRLLVGSRR-GLGRHQTLRHAVAWSYDHLSDAEKVLLERCSV
Mflv_2091|M.gilvum_PYR-GCK          --EQRDVELKGFSGSHTLYPVRSASASR----------------------
TH_1244|M.thermoresistible__bu      VDDGREVSLKGFPGRHRLFAVRGQAGFRPRPRPE----------------
MAV_5228|M.avium_104                GGSEAERLLTTIVFTDIVGSTERAAALGDYRWRDLLDNHDRIVRHELQRF
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               FLGGFDLDAAQAVA-GDSQVQRYQVVDELALLVDKSLVIAESGGGPTRYR
Mvan_5928|M.vanbaalenii_PYR-1       FAGGFDLDGAQAIT-VDGEVHRYEVVDLLTLLVDKSLLIAENTAGRTRYR
MLBr_01753|M.leprae_Br4923          ISGTFDLKVAYAVG-HDDLEEPDQVFDRLTMLIDKSLVIVEGRQGGSRYR
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           FAGGFDLQSACAVAGSADTHDDYEVLDLLDALVGKSLLIVDRLSGRSRFS
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                GGREVNTAGDGFVATFSSPSAAISCADALVDAVAALGIEVRVGIHAGEVE
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               LLETVRQYAQEKLAESGEVEAVRSRHVTYYKSVAKLLDAPTGTDHER-RL
Mvan_5928|M.vanbaalenii_PYR-1       LLETVRQYAQEKLGESGEADTLRARHRDHYTARAAELDAPSVAGHER-RL
MLBr_01753|M.leprae_Br4923          LLETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDIDHEQ-LV
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           MLETIREFAEEQLVTRGQALAARTAHARHFAQRLPDVAAVWDSPRQPEAY
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                VRGARKDDIAGMAVHIGARVAALAGPGEVLVSSTLRDIVTGSRHRFGDRG
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               AQAEDELDNLRSAFGWSLETRDFDSALELATSLHPVWMTRGQGREGLAWL
Mvan_5928|M.vanbaalenii_PYR-1       NQTDIEMDNLRAAFAWSRENANTDHSLLLASSLHPLWRARGRLQEGQAWF
MLBr_01753|M.leprae_Br4923          EQVETELDNLRSAFAWSRETGDIAGALQLASSLQPIWFGRGHMYEGLAWF
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           TWLTAELANLRLAFRWTADNNDLDDAASIATWVGFLGFLVNRFEP-----
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                ETALKGVPGQWRLYRLLREHAAAER-------------------------
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               EAGLGNEAGLGNEAGLGNEDVQVSPSTLARALADKVTLLAWTGSMAG---
Mvan_5928|M.vanbaalenii_PYR-1       DAALT-----DYEARPG----EADPAVYARALADRAFMDGHVGITDR---
MLBr_01753|M.leprae_Br4923          DSIFE---------HKNIEHLVAPKEVLARAVANKVMLHAILASSPPDGS
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                --------------------------------------------------
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               --FDDAERALTIARELADPALLIRALVARGVITAYDADVARPYFDEAAQL
Mvan_5928|M.vanbaalenii_PYR-1       --LDQAQKALAMARDIDDPALLVRALTACGGLAAYNADVARPLLAEAVDL
MLBr_01753|M.leprae_Br4923          DLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVARPYFAEAVEL
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           ----LTWVEEAIERAVDHPKLAFLHVLASQCYTTGRVQEAIRYADEAARL
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                --------------------------------------------------
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               ARELGDSWRLSQILSLQTRAAMAAG-DPIALEAAGEEGLRIAEAIGDRTT
Mvan_5928|M.vanbaalenii_PYR-1       ARSMGDKWMLAETLAWQAYAALMGGGDPVAARTAGEEARELADEMGDGFV
MLBr_01753|M.leprae_Br4923          ARTQGDKWTLSQIRLWGVVGFCVSG-DPVALRAAAEAADDLAQEIGDRFV
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           LAT--DRYEVPFGIEGWPSGACTSSGHPEQSVELCRTQLALGHDTHTLTL
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                --------------------------------------------------
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               SRECRGALGWVRAWRGDPIGALHQLGEAIAEASAAHDLLLLMISQVVQGF
Mvan_5928|M.vanbaalenii_PYR-1       SRICGWLLGIAHHFQGDLDAALALADGVVSESDVAHDTLNGCCGELVLAH
MLBr_01753|M.leprae_Br4923          SLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQTR
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           G-----CLVLALTIKGQCDEAEQLADALIESAEATRNPAALCYALLAYGF
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                --------------------------------------------------
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               TYAYVGDADGACACADAVFTSSAELVGANEGLGYATAAIACQAAGDATAA
Mvan_5928|M.vanbaalenii_PYR-1       SLAQRGDTDAARAAAQVSLNVAVEVSPVHAGLAHAALAVANLAAGDVTAA
MLBr_01753|M.leprae_Br4923          ALVHR-DVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAA
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           TFRDTNPASALAAMRRGLRIAQDTGNRNSE--------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                --------------------------------------------------
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               WKAYQKARELVGMDPQMAGVFPFGALAPLVS--GDLSAARRWADDVVSTS
Mvan_5928|M.vanbaalenii_PYR-1       EAASDSATRSFGPS-EVAGIQDPNVAAQIACTRGDLDTARSLVDGAVSIT
MLBr_01753|M.leprae_Br4923          VEASEACRPHLGADHGLVAIH-LELMAAVALARGDVIVARRLADNSVSAT
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                --------------------------------------------------
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               YGCYLSVALTARARVALAQGELGQADRDSHAALSCSAANGTTLGVADTLE
Mvan_5928|M.vanbaalenii_PYR-1       RGVHRASALTTRARIAIAQGDPEQAERNAHDALSLAAGVGARLEVPDTLE
MLBr_01753|M.leprae_Br4923          TGWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQASLGISDSME
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           -----THLAAVLCRVEAKYGDPLSALDHFTLAIHNHHEAGNTTLISTPLA
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                --------------------------------------------------
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               CLAELAATEGDRREAARLLASAEAIRHRTGEVRLKILDAHCEVVLAELRN
Mvan_5928|M.vanbaalenii_PYR-1       CLARVVGDGGSHHEAARLCGAAEAIRGRTGAVRFRIYDADHETTVTTLRD
MLBr_01753|M.leprae_Br4923          LLAELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLRG
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           VLAAFFDRLGRYEAAATIAGFAFHPITEASFP-------ELRTTISHLRD
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                --------------------------------------------------
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               ELGEQDFAAVWGQGAVISTDEVISYVRRGRGTRRRPSSGWGSLTPTEHDV
Mvan_5928|M.vanbaalenii_PYR-1       ALGDKAFEAAWTEGSATSITEAIAYAQRGRGERKRPSSGWASLTPTELDV
MLBr_01753|M.leprae_Br4923          AMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNV
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           ALGDHAYESFSQSGAAMTTAAMATYAYHQIDHARTEFQAR----------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                --------------------------------------------------
                                                                                      

Rv1359|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1394|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0123|M.marinum_M               VRLVQEGLSNKDIAARMFISPRTVQTHLTHVYTKLGLTSRIQLVHEVARH
Mvan_5928|M.vanbaalenii_PYR-1       VGLVSEGLSNKDIAARLFVSPRTVQTHLTHVYTKLCLASRVQLAQEAARH
MLBr_01753|M.leprae_Br4923          IRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARH
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
MAV_5228|M.avium_104                --------------------------------------------------
                                                                                      

Rv1359|M.tuberculosis_H37Rv         -
Mb1394|M.bovis_AF2122/97            -
MMAR_0123|M.marinum_M               A
Mvan_5928|M.vanbaalenii_PYR-1       T
MLBr_01753|M.leprae_Br4923          N
MSMEG_0545|M.smegmatis_MC2_155      -
MUL_2743|M.ulcerans_Agy99           -
Mflv_2091|M.gilvum_PYR-GCK          -
TH_1244|M.thermoresistible__bu      -
MAV_5228|M.avium_104                -