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DRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTSMRVALDRGEFF LVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTD PQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAID DFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAA RLRAFGCKAAQGWHFAKALPVDFFRE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1357c | - | - | 100% (307) | hypothetical protein Rv1357c |
| M. tuberculosis H37Rv | Rv1354c | - | 7e-34 | 32.81% (253) | hypothetical protein Rv1354c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1392c | - | 1e-177 | 100.00% (307) | hypothetical protein Mb1392c |
| M. gilvum PYR-GCK | Mflv_2073 | - | 2e-37 | 36.47% (266) | diguanylate cyclase/phosphodiesterase |
| M. leprae Br4923 | MLBr_01752 | - | 1e-106 | 73.95% (261) | hypothetical protein MLBr_01752 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_1410 | - | 2e-36 | 38.21% (280) | cyclic diguanylate phosphodiesterase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2196 | - | 1e-34 | 33.33% (258) | sensory box/response regulator |
| M. thermoresistible (build 8) | TH_0811 | - | 3e-32 | 32.28% (254) | sensory box/response regulator |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4640 | - | 1e-39 | 38.55% (262) | diguanylate cyclase/phosphodiesterase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK MHGGAVSNGRIRPLAGPWLWIPIGLTVALAVLLAVDDSRGLGVRT----V
Mvan_4640|M.vanbaalenii_PYR-1 -----MSGGRPR-LLGSCIAVPVGLTVALAVVLAVGGD-GAWVPV----L
MAV_1410|M.avium_104 MKRWAVNPWRRSGVPARVGWLLAGGYGTAALLVLLSSVRGWRGPYGTRPV
MSMEG_2196|M.smegmatis_MC2_155 -------------------------------------------------M
TH_0811|M.thermoresistible__bu -------------------------------------------------V
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK DNAITLTLSSYATLCAWLAARDARGRARKSWTLMAGALGAYALGDLTWLV
Mvan_4640|M.vanbaalenii_PYR-1 DDVIIVALSSCATVCAVLAAKSAEGRQRRAWATMAAAMGAWAVADLIWLV
MAV_1410|M.avium_104 DDLVMFVCLAVAAMCAARAARAASGRRRYGWLALTTALLGWAVGEVIWAV
MSMEG_2196|M.smegmatis_MC2_155 SESLDVLVTSVATQLMAVEAATSVSVSQQVLAELVS--------------
TH_0811|M.thermoresistible__bu STELDLLVTGVATKLMAADAATARDVSRRVLADLVR--------------
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK RES--AMHTQPFPSPADFFYLVFTILAVLSVLTMARYGAGSTRHSKLRVA
Mvan_4640|M.vanbaalenii_PYR-1 CEY--VLRVEPFPSPADFFYLAFSVLVVPAVLGMAQFDAWSRRQATLRIA
MAV_1410|M.avium_104 YDVRPEFEHAAHPAAAEMVLLLFPVGAMTSLVLLSQLS----RHSPRRLL
MSMEG_2196|M.smegmatis_MC2_155 ------------FFDVDVSFLRHNDHRAHATRLVAEWPPRPVDAATDPIA
TH_0811|M.thermoresistible__bu ------------AFELDFSFLRHNDHEIRASKLIAEWPVRENVPDPDPIG
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK LDGVTIALSAPLLAWIVALKDVYADNLGNPASLVIATAYPVLDIVALGVT
Mvan_4640|M.vanbaalenii_PYR-1 LDGVTVALCSFLLAWIFALDRVYEAYRDDKLALGLAFFYPVADMVILAVA
MAV_1410|M.avium_104 LDGLIVATSLFVISWVFVVEAQLREHTGTQVATLAEVFN---DIVLMTTA
MSMEG_2196|M.smegmatis_MC2_155 VVHFADADPVFAMAEHLKEPAVFRP-------------------------
TH_0811|M.thermoresistible__bu VVHFEGADPVFALAEHAKEIHIFRP-------------------------
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK VSVLVRADVRYRTVLTLVVAAFALTTIGDVGFAHAVVNGTYTTGSWLDVV
Mvan_4640|M.vanbaalenii_PYR-1 VAVLARVDAAHRAVPALLVFGFAVMTLTDSAFAYGVAVDSYRTGSFIDLG
MAV_1410|M.avium_104 ILTLSRARPGDRPSRSLLACGIATISVTDIAMVFYTGIGSYHTDDIGDLA
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------EPLYDDYQRTIE
TH_0811|M.thermoresistible__bu --------------------------------------EPATDEFQRLIE
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK WAAGLVCFAAAGQLARSATMPRRRALTVPPNVSVWLPYVPFMIAGTVGP-
Mvan_4640|M.vanbaalenii_PYR-1 WAVALVAICAAAQLSRENPQFRMPIVLVPSNTALWAPYVPLLLAGTIGP-
MAV_1410|M.avium_104 RVAGVGTLALAGLASVYEQPAPGSPDEIEFRTRLWLPYLPLILAAAVGWG
MSMEG_2196|M.smegmatis_MC2_155 AGRHIPATSMACVPLLSGDVTTGVLGFVKFGDREWLP-------------
TH_0811|M.thermoresistible__bu ESSGVPASTVAAVPLVSGEITTGVLGFVKYGDRQWHP-------------
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK ---LVVMSGVERFIVPFITAAVCLRQAVAAWENRYLLSLAAERALRDPLT
Mvan_4640|M.vanbaalenii_PYR-1 ---PLVMSGLEQLVVPVIVVAVCLRQVVAAWENRQLLRAAAEQALRDPLT
MAV_1410|M.avium_104 HAAGKAIHEPMLAALGILVAAVLARQFVVLVDNQNLLSEVAREAFRDNLT
MSMEG_2196|M.smegmatis_MC2_155 -----------AELNALKAIASLFAQVQARIEAEERLRYLADH---DHLT
TH_0811|M.thermoresistible__bu -----------DELNALKAIASLFAQVQARVEAEERLRYLAEH---DDLT
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK GLANRSLFQDRLAHALMLRERDNRSVAVISLDLDDFKLVNDSLGHPVADS
Mvan_4640|M.vanbaalenii_PYR-1 ELANQRLFYDRLAHALTLSSREGHSVAVVSLDLDDFKLVNDSVGHPEADS
MAV_1410|M.avium_104 GLANRALFVHRLEQAVARRHPDGTPIAVLCLDLDNFKAVNDALGHPAGDE
MSMEG_2196|M.smegmatis_MC2_155 GLYNRRALMAHLEARLAPGQPG--PVAVMFFDLDRLKAINDYLGHTAGDA
TH_0811|M.thermoresistible__bu GLHNRRALLAHLDARLAAGQPG--PVSALYFDLDRLKAVNDYLGHTVGDW
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK LLVSAGRRIIGCVRTGDTVARVGGDEFALLLEG--DASSPDLIAQRVADA
Mvan_4640|M.vanbaalenii_PYR-1 LLVRVGQRIADCVRAGDTVARIQGDEFALLLEG--EHDDSKLIAERVVDA
MAV_1410|M.avium_104 LLVRVAERLTAALGDSGTIARLGGDEFAAVIEA--SVDESQAAAHRILEA
MSMEG_2196|M.smegmatis_MC2_155 FISILAQRLQRGDDAPKLIARLGGDEFVVVPDDPMSLDEATALAYRLQSV
TH_0811|M.thermoresistible__bu FIRVLAERLREGAGPDDLIARLGGDEFVVVPSGPVDADAALELANRLRSR
Rv1357c|M.tuberculosis_H37Rv -------------------------------MDRCCQRATAFACALR---
Mb1392c|M.bovis_AF2122/97 -------------------------------MDRCCQRATAFACALR---
MLBr_01752|M.leprae_Br4923 -----------------------------------MPIEGAMRSSSL---
Mflv_2073|M.gilvum_PYR-GCK FAEPFIVDGHQILMHPSIGVAVTPPDEAEVSAQTLITRADMAMYTAK---
Mvan_4640|M.vanbaalenii_PYR-1 FDEPFVLHGEHILLRPSVGVAAASPGEAEVAPETMVMRAETAMNVAK---
MAV_1410|M.avium_104 FTGAILIDGIPITVRPSIG-FTVCTGASTCTVDQLLRHADLAMYAAKREG
MSMEG_2196|M.smegmatis_MC2_155 LRERVTVDGEMLTRTVSIGIAQGIPGKD--STSDVLNRADHAVLTAK---
TH_0811|M.thermoresistible__bu LQQQVCVDGEMLTRTASIGVAQGTPGRD--TTSDLLRRADQAVLTAK---
Rv1357c|M.tuberculosis_H37Rv -------------------------PTKLIDYEEMFRGAMQARAMVANPD
Mb1392c|M.bovis_AF2122/97 -------------------------PTKLIDYEEMFRGAMQARAMVANPD
MLBr_01752|M.leprae_Br4923 -------------------------PDGCSDRSADSRGSGEVKDRSSG-W
Mflv_2073|M.gilvum_PYR-GCK -------------------------KSRSSRVYTFDADMTLPGPDADSMT
Mvan_4640|M.vanbaalenii_PYR-1 -------------------------RSRSSRVHVFDATLESAAPDVVAPE
MAV_1410|M.avium_104 GQCIRSFMPDLPLPYAFPPPPGSAAPTAVAAVAAGGNGAAPASPPQVATA
MSMEG_2196|M.smegmatis_MC2_155 -------------------------GSGGNRVAVFSDAMAMEIDFRNDIE
TH_0811|M.thermoresistible__bu -------------------------SAGGNQITVFTDDMSLEAEFRNDIE
Rv1357c|M.tuberculosis_H37Rv QWADSDRDQVN---------------------------------------
Mb1392c|M.bovis_AF2122/97 QWADSDRDQVN---------------------------------------
MLBr_01752|M.leprae_Br4923 FYGHHDREQRS---------------------------------------
Mflv_2073|M.gilvum_PYR-GCK ESPDRKPGAGA---------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 RGSPQNWPDGA---------------------------------------
MAV_1410|M.avium_104 ATSSPSPHDAARRPPRGIRAALGMLAIGVVAFSVSSVAHPDAGHGIFSAT
MSMEG_2196|M.smegmatis_MC2_155 LHLQS---------------------------------------------
TH_0811|M.thermoresistible__bu LHLQS---------------------------------------------
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 ALYSALNAVAAGLIALRACRIPADRWAWALIAAGMACSAVGDVVYAVWVP
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 DGRSPSVADPEYLAYYPFVYAGLLLLMRARLKRLPIAVQLDSVVCALTLA
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 AVAAALTAGPLHQAAVHAPKTVWVGLAYPWCDLMLLALAAGMLPILGWRN
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 EIRWALLVAGLVLFAVADGAYLFQTAAGSYRVGSLLDVCWPASSVLIAMA
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 SWAPPPATATQARRRFSPYVTPVASTIVALGVIVLAHHSRSAATLAALSL
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
Rv1357c|M.tuberculosis_H37Rv ---------------------------------TRHYLSTSMR-------
Mb1392c|M.bovis_AF2122/97 ---------------------------------TRHYLSTSMR-------
MLBr_01752|M.leprae_Br4923 ---------------------------------VHDGLLQVIP-------
Mflv_2073|M.gilvum_PYR-GCK ---------------------------------AKVQLLGELR-------
Mvan_4640|M.vanbaalenii_PYR-1 ---------------------------------AKVRLLGELR-------
MAV_1410|M.avium_104 VVGAGRFSLTFRDVSLLHSHDRHAMTDELTALPNRRQLVTALQGLPASAS
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 PGAGSMPSRANPRRALLLLSLSDFHEITESIGRQFGDELLCHIANRLAGS
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 VRRDDLLARVGDDQFAVLLADGANLTAASAQAGRLLEALSEPIALDPITV
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
Rv1357c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1392c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01752|M.leprae_Br4923 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 QVDGRIAIALCPDHCDHPRELLSRAETALAHAKSARSKIAVYDSAFEAHR
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
Rv1357c|M.tuberculosis_H37Rv ------------VALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLG
Mb1392c|M.bovis_AF2122/97 ------------VALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLG
MLBr_01752|M.leprae_Br4923 ------------AALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLG
Mflv_2073|M.gilvum_PYR-GCK ------------RAIDAAELEMVYQPKVALRTGRIIGVEALLRWPHPRLG
Mvan_4640|M.vanbaalenii_PYR-1 ------------RAIDNGEFHMVYQPIVDLRSGFIVGVEALLRWPHPRLG
MAV_1410|M.avium_104 DNDTNLIEELRTALFDTDELKLHYQPKIDGRDGSIHSVEAVLRWQHPTRG
MSMEG_2196|M.smegmatis_MC2_155 -------------VIEGGALVLHYLPEIDMRTGEVLAAEALVRWEHPTRG
TH_0811|M.thermoresistible__bu -------------VIQDEALLLHFLPEVDMRTGEILATEALVRWHHPTRG
:: : : : * : . ..**::** ** *
Rv1357c|M.tuberculosis_H37Rv TLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNV
Mb1392c|M.bovis_AF2122/97 TLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNV
MLBr_01752|M.leprae_Br4923 TLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNV
Mflv_2073|M.gilvum_PYR-GCK LLYPGAFMSLVRQHGLMRPVSDLVVDKVLDAATAWKAEGVRIP--VAVNL
Mvan_4640|M.vanbaalenii_PYR-1 MLSPDAFLPLVRQHGLMRPVTEVVLDNVLDDAARWMADGVPMP--VAVNL
MAV_1410|M.avium_104 TLLPEEFLPVAERAGLMRKISNRTLSMALQQVRSWREEGLRLT--VAVNL
MSMEG_2196|M.smegmatis_MC2_155 LLSPDSFIGVAESINLAGELGRWVLRTACAEFSRWRANGVGRNIVLRINV
TH_0811|M.thermoresistible__bu LLAPDTFIGVAESVNLAGELGRWVMRTACGEFAKWRAEGIGLDAVLRINV
* * *: .. .: : .: . * .. : :*:
Rv1357c|M.tuberculosis_H37Rv SASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQE
Mb1392c|M.bovis_AF2122/97 SASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQE
MLBr_01752|M.leprae_Br4923 SARNIRDPSFLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQE
Mflv_2073|M.gilvum_PYR-GCK FAPTLRDAQLPDRLLGALEKRGLTADMLTVEITEDLVVDDLGTVTDVLQQ
Mvan_4640|M.vanbaalenii_PYR-1 FAPFLRDAQLPSALCQALERRGLPTDLLTVEITEDLVLHDFDVVTGVLGQ
MAV_1410|M.avium_104 STTNLLDIELVGTVERLLANYDLPADALILEITESALVDSVR-SRNTVTA
MSMEG_2196|M.smegmatis_MC2_155 SPVQLVTDGFVESVAGIMKEFGLPRGSVCLEITESVVVQDIETTRTTLTG
TH_0811|M.thermoresistible__bu SPVQLVTDGFVASVADIIDEFGLDGSSVCLEITESVVVQDIKTTRITLEG
. : : : : . .* : :*::*. : :
Rv1357c|M.tuberculosis_H37Rv LSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLA
Mb1392c|M.bovis_AF2122/97 LSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLA
MLBr_01752|M.leprae_Br4923 LSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDIRGRLA
Mflv_2073|M.gilvum_PYR-GCK LRHCGIRVAIDDFGSGYSALSYLRDLPIDEIKLDRYFVAPVTEDPRA---
Mvan_4640|M.vanbaalenii_PYR-1 LREQGIRVAIDDFGSGFSALSYLRELRIDEIKLDRHFIATVASDPRA---
MAV_1410|M.avium_104 LQRLGIRISIDDYGTGWSSLARLQEVSVDELKLDRIFVARLAHDARS---
MSMEG_2196|M.smegmatis_MC2_155 LHNVGVQVAIDDFGTGYSVLSLLKSLPVDTLKIDRSFVAELGSNPGD---
TH_0811|M.thermoresistible__bu LNEVGVQVAIDDFGTGYSVLSHLKTLPVDTLKIDKGFVQDLGNSPGD---
* *: ::***:* *:* *: * : :* :*: *: : .
Rv1357c|M.tuberculosis_H37Rv NEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKAL
Mb1392c|M.bovis_AF2122/97 NEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKAL
MLBr_01752|M.leprae_Br4923 DEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKAL
Mflv_2073|M.gilvum_PYR-GCK -AAVVSAVIDLAHDLGIVVVAEGVEEPVTAHWLRGKQCDIAQGYYFGRPT
Mvan_4640|M.vanbaalenii_PYR-1 -AAVVRAVIDLTHDLGSVVVAEGVEEPATAAWLRDRGCDMAQGYYFGKPI
MAV_1410|M.avium_104 -VAIVRSTVALADNLGADLVAEGVENEDTLDALRRYGCNITQGFVHTPPL
MSMEG_2196|M.smegmatis_MC2_155 -LPIVRAVIALAGAFGLQLVAEGVETERAALTLLRHGCYRAQGFLLSKPI
TH_0811|M.thermoresistible__bu -LAIVRAIIALAEAFGLQLVAEGVETEAAALTLLRHGCHRAQGFLLSRPI
:. : : * :* : *: ** * * :**: .
Rv1357c|M.tuberculosis_H37Rv PVDFFRE-----------------
Mb1392c|M.bovis_AF2122/97 PVDFFRE-----------------
MLBr_01752|M.leprae_Br4923 PADFFTE-----------------
Mflv_2073|M.gilvum_PYR-GCK DRAHLPGLVEAAALPRLDVVAD--
Mvan_4640|M.vanbaalenii_PYR-1 EAADVPGLVRMAKDPA--------
MAV_1410|M.avium_104 PPDELRAWIASHAPDPSQSRG---
MSMEG_2196|M.smegmatis_MC2_155 LGSEMQTLLAKGRVPVHFSAAPRM
TH_0811|M.thermoresistible__bu PSNEMRELLARGRIPMRFSATP--
.