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MLQRIARLAIAAPRRIIGFAVFVFIAAAVFGVPVADSLSPGGFQDPRSESARAIEVLTDKFGQSGQKMLI VVTAAAGADSPPAREVGTDIVEVLRRSPLVYNVTSPWTVPPTAAADLLSTDGKSGLIVVNVKGGENDAQN HAQTLSDEVAHDRDGVTVRAGGSAMEYAQINRQNKDDLLVMELIAIPLSFLVLIWVFGGLLAAGLPMAQA VLAVVGSMAVLRLVTFATEVSTFALNLSTALGLALAIDYTLLIVSRYRDELAEGSDRDEALIRTMALRGA RCCFRRSPWRCRCRRLRCSRCTF
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv1145 | mmpL13a | - | 100% (303) | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13A |
M. tuberculosis H37Rv | Rv0206c | mmpL3 | 1e-25 | 27.47% (273) | transmembrane transport protein MmpL3 |
M. tuberculosis H37Rv | Rv0202c | mmpL11 | 1e-15 | 25.74% (272) | transmembrane transport protein MmpL11 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1177 | mmpL13 | 1e-151 | 97.89% (284) | transmembrane transport protein MmpL13 |
M. gilvum PYR-GCK | Mflv_2131 | - | 4e-95 | 62.32% (284) | MMPL domain-containing protein |
M. leprae Br4923 | MLBr_02620 | - | 1e-24 | 26.33% (281) | hypothetical protein MLBr_02620 |
M. abscessus ATCC 19977 | MAB_1287 | - | 5e-82 | 54.23% (284) | MmpL family membrane protein |
M. marinum M | MMAR_4305 | mmpL13 | 1e-120 | 77.70% (287) | transmembrane transport protein MmpL13 |
M. avium 104 | MAV_1287 | - | 1e-123 | 78.87% (284) | mmpL protein |
M. smegmatis MC2 155 | MSMEG_5178 | - | 1e-92 | 61.32% (287) | integral membrane protein |
M. thermoresistible (build 8) | TH_1538 | - | 1e-85 | 57.04% (284) | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13B |
M. ulcerans Agy99 | MUL_0989 | mmpL13 | 1e-119 | 77.35% (287) | transmembrane transport protein MmpL13 |
M. vanbaalenii PYR-1 | Mvan_4573 | - | 3e-96 | 62.37% (287) | MMPL domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Rv1145|M.tuberculosis_H37Rv -MLQRIARLAIAAPRRIIGFAVFVFIAAAVFGVPVADSLSPGGFQDPRSE Mb1177|M.bovis_AF2122/97 -MLQRIARLAIAAPRRIIGFAVFVFIAAAVFGVPVADSLSPGGFQDPRSE MAV_1287|M.avium_104 -MLQKIARVAIAAPRRIIALGVLVFLAAAVFGIPVAKSLSPGGFQDPDSE MMAR_4305|M.marinum_M -MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSPGGFQDPNAE MUL_0989|M.ulcerans_Agy99 -MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSRGGFQDPNAE Mflv_2131|M.gilvum_PYR-GCK -MLHRIARLAIAAPRRVLMAALLVAIACGVFGIPVVTHLSAGGFQDPTSE Mvan_4573|M.vanbaalenii_PYR-1 -MLHRIALLAIAAPRRVLVVALLIMVGCGIFGAPVAKHLSAGGFQDPTSE MSMEG_5178|M.smegmatis_MC2_155 -MLQRIATTAIAAPRRILVVAALVMIAAGIFGIPVANKLSAGGFQDPTAE TH_1538|M.thermoresistible__bu -MLETLARRIVAAPRRVLALVVLVIVGAAMFGLPVAGSLSAGGFRDPHSE MAB_1287|M.abscessus_ATCC_1997 MMLERLARSVIAAPRLVLGMALLIAIAAALFGVPVTKHLAAGGQQDPNSE MLBr_02620|M.leprae_Br4923 -MFAWWGRTVYRYRFIVIGITVALCLCGGVFGLSLGKHVTQSGFYDDSSQ *: . :: : : .:** .: :: .* * :: Rv1145|M.tuberculosis_H37Rv SARAIEVLTDKFGQSGQKMLIVVTAA---AGADSPPAREVGTDIVEVLRR Mb1177|M.bovis_AF2122/97 SARAIEVLTDKFGQSGQKMLIVVTAA---AGADSPPAREVGTDIVEVLRR MAV_1287|M.avium_104 SARAIGVLTDKFGQSGQQMLILVTAP---GGSNSDPARRVGTELVEQLQR MMAR_4305|M.marinum_M SARAIKVLADKFGQSGQQMLILVTAP---GGVGTERARAVGTDIVAELNH MUL_0989|M.ulcerans_Agy99 SARAIKVLADKFGQSGQQMLILVTAP---GGVGTERARAVGTDIVAELNH Mflv_2131|M.gilvum_PYR-GCK SARATQMLVDTFGQGDMELILAVTSD---DGAQSPAARDVGVELVERLSD Mvan_4573|M.vanbaalenii_PYR-1 SARATQLLVDKFDQGDMELLISITDDNSADGANSPAARAVGTDLADRLAA MSMEG_5178|M.smegmatis_MC2_155 SARATQLLADKFHRGDMQLVIAVTAEAPGGRADGGRAREVGTEIVSELKA TH_1538|M.thermoresistible__bu SAQASALLAERFDQTDMQLLVTVSSS---AGVYGEAARRVGTEIVAALEA MAB_1287|M.abscessus_ATCC_1997 SAYVTKALRDKFDISDQSLVFMLTSE---QGVKSPQMRAVAADLERQLKD MLBr_02620|M.leprae_Br4923 SVKASILGDQVYGRDRSGHIVAIFHAPDGKTVNDPAWAKKITDELNQFQR *. . : : :. : .: : Rv1145|M.tuberculosis_H37Rv --SPLVYNVTSPWTVP---PTAAADLLSTDGKSGLIVVNVKGGENDAQNH Mb1177|M.bovis_AF2122/97 --SPLVYNVTSPWTVP---PTAAADLLSTDGKSGLIVVNVKGGENDAQNH MAV_1287|M.avium_104 --SPLVYNVSSPWTAP---PQASADLVSRDGKSGLIVVNLKGGENFVQNN MMAR_4305|M.marinum_M --SPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQKN MUL_0989|M.ulcerans_Agy99 --SPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQKN Mflv_2131|M.gilvum_PYR-GCK --SPHVAAITSAWTSP---PSAAPALISEDGRTGLIVAGITGGESGAQKL Mvan_4573|M.vanbaalenii_PYR-1 --SPHVGAVTSAWTAP---PSAAPALVSEDGRTGLIIAGITGGESEAQKH MSMEG_5178|M.smegmatis_MC2_155 --SPYVTEVTSAWTAP---PSAAAALVSKDARTGLIVAGLNGGENGAQQH TH_1538|M.thermoresistible__bu --SPQVAGVQSPWTVP---PGAGDRLVSEDATAGLIVAPIRGNETESSDI MAB_1287|M.abscessus_ATCC_1997 --SGVVINLTSAWTAP---PQVAEELLGADGKAGLIVAGLTGGENDAQKH MLBr_02620|M.leprae_Br4923 NNSNKVTGWAGYLRASDTTNTVVQGMATPDKKYTFVSIPLKGDDDDTILN * * . . : * :: : *.: Rv1145|M.tuberculosis_H37Rv AQTLSDEVAHDRDGVTVRAGGSAMEYAQINRQNKDDLLVMELIAIPLSFL Mb1177|M.bovis_AF2122/97 AQTLSDEVAHDRDGVTVRAGGSAMEYAQINRQNKDDLLVMELIAIPLSFL MAV_1287|M.avium_104 AQTLADQFVHDRDGVTVRAGGAAMQYAQINTQNQADLLVMEMIALPLSFL MMAR_4305|M.marinum_M AQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLSFL MUL_0989|M.ulcerans_Agy99 AQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLSFL Mflv_2131|M.gilvum_PYR-GCK AKALTDELVYDRDGVTVRAGGAAMTYVQINTQTEKDLLLMESIAIPLSFV Mvan_4573|M.vanbaalenii_PYR-1 AKTLTDELVRDRDGVTVRAGGVAMTYVQINTQSEKDLLMMESIAIPLSFV MSMEG_5178|M.smegmatis_MC2_155 AKELTDQFVRDHDGVRVRAGGEAMIYVQINGQSEKDLLMMESIAIPLSFV TH_1538|M.thermoresistible__bu ARQLAAAVGSDRDRVNVRAGGPALVNAQIDTQTEHDLLVMEAIAIPLSFV MAB_1287|M.abscessus_ATCC_1997 AAKLIKSLAVDRDGVAVKAGGVATLYNQIVTQSEKDLLVMESIAIPISFV MLBr_02620|M.leprae_Br4923 NYKAIAPDLQKLDGGTVQLAGLDPIANALTSTIATDQRRMEVLALPLVAV . * *: .* : * ** :*:*: : Rv1145|M.tuberculosis_H37Rv VLIWVFGGLLAAGLPMAQAVLAVVGSMAVLRLVTFATEVSTFALNLSTAL Mb1177|M.bovis_AF2122/97 VLIWVFGGLLAAGLPMAQAVLAVVGSMAVLRLVTFATEVSTFALNLSTAL MAV_1287|M.avium_104 VLIWVFGGLLAAALPMALGALAVVGSMSVLRLITFTTEVSIFALNLSTAL MMAR_4305|M.marinum_M VLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLSTAL MUL_0989|M.ulcerans_Agy99 VLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLSTAL Mflv_2131|M.gilvum_PYR-GCK VLVWVFGGLLAAALPLAVGVFAILGSMAVLRGFTLVTDVSIFALNLSIAM Mvan_4573|M.vanbaalenii_PYR-1 VLVWVFGGLLAAALPLAVGAFAILGSMAVLRAVTLVTDVSIFALNLSIAM MSMEG_5178|M.smegmatis_MC2_155 VLVWVFGGLLAAALPLAVGGFAILGSLAVLRLFTMVTDVSIFALNLTVAM TH_1538|M.thermoresistible__bu VLVWVFGGLLAAALPLAVGVLAIVGSMAVLRTFTMFTEVSVFALNLSIAM MAB_1287|M.abscessus_ATCC_1997 VLVWIFGGLYAALLPLVVGVFSIVGAMSILRGLTYVTDVSVFALNLAVAM MLBr_02620|M.leprae_Br4923 VLFLVFGGVIAACLPVMVGGLSIAGALGILRFIALFGPVHFFAQPVVSLI **. :***: ** **: . ::: *::.:** .: * ** : : Rv1145|M.tuberculosis_H37Rv GLALAIDYTLLIVSRYRDELAEGSDRDEALIRTMALRG------------ Mb1177|M.bovis_AF2122/97 GLALAIDYTLLIVSRYRDELAEGSDRDEALIRTMATSGRTVLFSAVTVAL MAV_1287|M.avium_104 GLALAIDYTLLIVSRYRDELAEGHDRDQALIRTMATSGRTVLFSAVTVAL MMAR_4305|M.marinum_M GLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTVAL MUL_0989|M.ulcerans_Agy99 GLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTVAL Mflv_2131|M.gilvum_PYR-GCK GLALAIDYTLLIISRYRDELADGHDRDTALLRTMTTAGRTVVFSATTVAL Mvan_4573|M.vanbaalenii_PYR-1 GLALAIDYTLLIISRYRDELAEGHDRDSALVRTMMTAGRTVLFSALTVAL MSMEG_5178|M.smegmatis_MC2_155 GLALAIDYTLLIISRFRDELAEGADRETALVRTMMTAGRTVLFSAMTVAL TH_1538|M.thermoresistible__bu GLALAIDYTLLLLNRYRDELAEGCSREQAVIRTMTSAGRTVIFSAVIVAT MAB_1287|M.abscessus_ATCC_1997 GLALAIDYSLLIISRYREEVNAGKPRDEALVLTMTTAGRTVLFSALTVAL MLBr_02620|M.leprae_Br4923 GLGIAVDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIAA **.:*:** *:::.*:*:*: * : *: *: * Rv1145|M.tuberculosis_H37Rv ---------------------ARCCFRRSP-------------------- Mb1177|M.bovis_AF2122/97 SMSATALFPMYFLKSFAYAGVATVAFVATASIVITPAAIVLLGPRLDALD MAV_1287|M.avium_104 SMSATVAFPMYFLKSFAYAGVATVAFVATASIVITPAAIVLLGDRLDALD MMAR_4305|M.marinum_M SMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDALN MUL_0989|M.ulcerans_Agy99 SMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDALN Mflv_2131|M.gilvum_PYR-GCK SMVAMVLFPMYFLKSFAYAGIAVVSFAALAAIVVTPAAIALAGDRLDALD Mvan_4573|M.vanbaalenii_PYR-1 SMVAMVLFPMYFLKSFAYAGIAVVGFAAVAAIVVAPAAIVLAGARLDSMD MSMEG_5178|M.smegmatis_MC2_155 SMVAMVLFPMYFLKSFAYAGIAVVALAATAAIVLTPAAIVLLGDRLDAYD TH_1538|M.thermoresistible__bu SMVPLALFPMYFLRSFAYAGVGVVAFALCAALVITPAAITVLGARLDSWD MAB_1287|M.abscessus_ATCC_1997 ALVALILFPMYFLKSFGYAGVAVVFVGAIAALVIVPAVVTLLGDRIDALD MLBr_02620|M.leprae_Br4923 SGASLLLLPQGFVKSLTYALIAAVTLAALLSITLLPACLAILAKHVDALG . . Rv1145|M.tuberculosis_H37Rv WRCRCRRLR----------------------------------CSRCTF- Mb1177|M.bovis_AF2122/97 VRRLVRRLLGRP-----------------DPVHKPVKQLFWYRSSKFVMR MAV_1287|M.avium_104 VRRLLRRALRRA-----------------QPVRKPVEQLFWYRSSKFVMR MMAR_4305|M.marinum_M VRRLARRMLGRP-----------------EPQHKPVDQLFWYRSTKFVMR MUL_0989|M.ulcerans_Agy99 VRRLARRMLGRP-----------------KPQHKPVDQLFWYRSTKFVMR Mflv_2131|M.gilvum_PYR-GCK VRRLVRRILGRP-----------------DPVAKPVEQNFWYRSTTFVMR Mvan_4573|M.vanbaalenii_PYR-1 VRRLVRRVLGRP-----------------EPVAKPVEQMFWYRSTKFVMR MSMEG_5178|M.smegmatis_MC2_155 VRRFFRRVFGRP-----------------EPEPKPVEQGFWYRTAKAAMR TH_1538|M.thermoresistible__bu IRRLIRRLMRRTP-------------AAAEPAPRAVCGSKWYRWAKAVMR MAB_1287|M.abscessus_ATCC_1997 VRRLIRRVLGRP-----------------EPVAKDVTQSFWYRTTKRVMA MLBr_02620|M.leprae_Br4923 VRTLFRVPLLRNWRMSHACLNWLADRLQKTKTREEVEAGFWGKLVNFVMK * * .: Rv1145|M.tuberculosis_H37Rv -------------------------------------------------- Mb1177|M.bovis_AF2122/97 RWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDF MAV_1287|M.avium_104 RWAPVGLIVVGLLLLLGLPFFSVKWGFPDDRVLPRSASAHQVGDRLRSGF MMAR_4305|M.marinum_M RALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRTNF MUL_0989|M.ulcerans_Agy99 RALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRTNF Mflv_2131|M.gilvum_PYR-GCK RSIPIGGVVVVLLVLLGAPFLGATWGFPDDRVLPETASARQIGDELRQDF Mvan_4573|M.vanbaalenii_PYR-1 RSIPIGVVVVTLLLLLGAPFLGANWGFPDDRVLPQSASARQVGDELRTDF MSMEG_5178|M.smegmatis_MC2_155 RAVPIGVGIIALLVLLGVPFTGIKWGFPDDRVLPQSASARQIGDEMRTNF TH_1538|M.thermoresistible__bu HWLVAGLAVTVVLLLLGAPFLGVRWGFPDERVLPRSASAHQVGHELRTNF MAB_1287|M.abscessus_ATCC_1997 RAVPIAIIIVSALVVLGLPFLDGKFGFPDDRVLPASASAHQVGNEMRRNF MLBr_02620|M.leprae_Br4923 RPLVFAIPIVIGMILLVIPLGNLSFGGMSEKYLPPNNAVRQSQEHFDQLF Rv1145|M.tuberculosis_H37Rv -------------------------------------------------- Mb1177|M.bovis_AF2122/97 GHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGS MAV_1287|M.avium_104 AHDSATSVPVVIPDAAGLSPADLDDYAAALSRVPDVSAVSAPGGTFTGGT MMAR_4305|M.marinum_M AHDLAMAVPVVVPDVRGLVPADLDGYAADLSRVPDVASVTAPSGTFVNGS MUL_0989|M.ulcerans_Agy99 AHDLAMAVPVVVPDVHGLVPADLDGYAADLSRVPDVASVTAPSGTFVNGS Mflv_2131|M.gilvum_PYR-GCK AVDSSTNVVVVLPDADGISREDFDAYAIALSGVADVSSVSAPSGTFIGGA Mvan_4573|M.vanbaalenii_PYR-1 AVDSSANVVVVLPDAEGLGPDALDGYAAELSRVQDVSSVSAPGGTFVDGA MSMEG_5178|M.smegmatis_MC2_155 AVDSATSVTVVLPDATTVAPAEIDRYAARLSQVADVSSVSAPGGTDVQGR TH_1538|M.thermoresistible__bu ATDSASDVTVVLPDAPGLTADELAGYAARLSEVTDVAWVSAPAGTFVRGR MAB_1287|M.abscessus_ATCC_1997 NNNSSTNLSVIAEGVGSVPPREIDEYAADLSNIEDVKEVAAPTGAFIRGM MLBr_02620|M.leprae_Br4923 PGYRTNPLTLVIQTSN-HQPVTDQEIADIRSKAMAISGFIEPDNNYVNMW Rv1145|M.tuberculosis_H37Rv -------------------------------------------------- Mb1177|M.bovis_AF2122/97 WVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVV MAV_1287|M.avium_104 RVGPPAGATGLGDGSAFLTVSSTAPLFSTANDVQLKRLHEVPGPAGRSVE MMAR_4305|M.marinum_M RVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRTVE MUL_0989|M.ulcerans_Agy99 RVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRTVE Mflv_2131|M.gilvum_PYR-GCK RAGPPSAATGSADGSAFLTIGSRAPLFTDASEVQLDRLHAIAPPGDRQVL Mvan_4573|M.vanbaalenii_PYR-1 KAGPPSAATGIAEGSAFLTIGSTAPLFTDASETQLDRLHDVAPPEGRDVL MSMEG_5178|M.smegmatis_MC2_155 HVGPPSAATGIGDGSAFLTVGSDAPLFSDASEAQLDALHAVAAH--AEVQ TH_1538|M.thermoresistible__bu SVGPPSAPTGIADGSAFVTVGSVAPLFSDDSLEQLNDIRAVPAPGGTAVQ MAB_1287|M.abscessus_ATCC_1997 KVGPSASATGIKNDTALFTVQTAAKPYTEAAERQLDAIHALPGPADVLVR MLBr_02620|M.leprae_Br4923 QERTVAPGASKDPSVRVLQNG---LINPNDASKKINELRSITPPKGLTVS Rv1145|M.tuberculosis_H37Rv -------------------------------------------------- Mb1177|M.bovis_AF2122/97 MAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKALVC MAV_1287|M.avium_104 MGGVAQVNRDSVDAVTDRLPLVLGLMAAITFVLLFLLTGSVLLPAKALAC MMAR_4305|M.marinum_M MAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKALIC MUL_0989|M.ulcerans_Agy99 MAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKALIC Mflv_2131|M.gilvum_PYR-GCK LTGLAQINRDSADAITSRLPLVLAVIAAITFVLLFVLTGSVVLPLKALVL Mvan_4573|M.vanbaalenii_PYR-1 LTGLAQINRDSADAITSRLPTVLAVIAAITFVLLFLLTGSVVLPLKALVL MSMEG_5178|M.smegmatis_MC2_155 FTGVAQVNRDSSQAITSRLPLVLGIIAGITFVLLFLLTGSVVLPLKALVL TH_1538|M.thermoresistible__bu LTGTAQINHDIVVAVTSRLTVVLTVIALTTLVWLFLLTGSIVLPIKALVL MAB_1287|M.abscessus_ATCC_1997 IGGGAQLDRDAVDGIVHKLPLVLAIIAVVTFVLLFLLTGSVVLPIKALVL MLBr_02620|M.leprae_Br4923 VGGTPALEQDSIHSLVAQAPLMVIMLITTTMLLMFLAFGSFVLPIKAAVM Rv1145|M.tuberculosis_H37Rv -------------------------------------------------- Mb1177|M.bovis_AF2122/97 NVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMD MAV_1287|M.avium_104 NFLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGLSMD MMAR_4305|M.marinum_M NVLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGLSMD MUL_0989|M.ulcerans_Agy99 NVLSLTAAFGALVWIFQDGHLGALGTIPSGTLVANMPVLLFCIAFGLSMD Mflv_2131|M.gilvum_PYR-GCK NVLSLTAAFGALVWIFQEGHLGALGTTPTGTLVATMPVLLFCIAFGLSMD Mvan_4573|M.vanbaalenii_PYR-1 NVLSLTAAFGALVWIFQDGHLGALGTTPTGTLVANMPVLLFCIAFGLSMD MSMEG_5178|M.smegmatis_MC2_155 NVLSLSAAFGALVWIFQDGHLGALGTTPTGTLVANLPVLLFCIAFGLSMD TH_1538|M.thermoresistible__bu NALSLTAAFGALVWIFQDGHLGALGTTPSGTMAVTMPALLLCVAFGISMD MAB_1287|M.abscessus_ATCC_1997 NVLSLTATFGALIWIFQEGHLGGFGTEVTGTIVATMPMLLFCIAFGLSMD MLBr_02620|M.leprae_Br4923 SALTLGSTMGILTWIFVDGHLSKWLNFTPTPLMVVIIALVVAVGYGLATD Rv1145|M.tuberculosis_H37Rv -------------------------------------------------- Mb1177|M.bovis_AF2122/97 YEVFLVSRIREYWLESGAAR------PARRSVAEVHAANDESVALGVART MAV_1287|M.avium_104 YEVFLLSRIREYWLASGAAR------PARPTPKRAHAANDESVALGVART MMAR_4305|M.marinum_M YEVFLVARIREYWLASGAAR------PATPSPAQAHAANDESVALGLART MUL_0989|M.ulcerans_Agy99 YEVFLVARIREYWLASGAAG------PATPSPAQAHAANDESVALGLART Mflv_2131|M.gilvum_PYR-GCK YEVFLVSRIREYWLETG--------------------ENGRSVALGLART Mvan_4573|M.vanbaalenii_PYR-1 YEVFLVSRIREYWLASGGAGADSSTAHQRSDDLAPHVRSDESVALGLART MSMEG_5178|M.smegmatis_MC2_155 YEVFLVSRIREFWLQSDQS----------------RAANEESVALGLAHT TH_1538|M.thermoresistible__bu YEVFLIARIREHWLASSRTA----------------AANDEAVALGVART MAB_1287|M.abscessus_ATCC_1997 YEVFLISRIREYWMASGRTR----------------ADNDEAVALGVART MLBr_02620|M.leprae_Br4923 YEVFLVSRMVEARAESMSTQ--------------------EAVRIGTAST Rv1145|M.tuberculosis_H37Rv -------------------------------------------------- Mb1177|M.bovis_AF2122/97 GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVP MAV_1287|M.avium_104 GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVFADATLVRMVVVP MMAR_4305|M.marinum_M GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVLVP MUL_0989|M.ulcerans_Agy99 GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAMAADATLVRMVLVP Mflv_2131|M.gilvum_PYR-GCK GRVVTAAALVMSISFAALIAAQVSFMRMFGGGLTLAVLVDATLVRMLLVP Mvan_4573|M.vanbaalenii_PYR-1 GRVVTAAALLMSISFAALIAAKVAFMRMFGVGLTLAILADATLVRMLLVP MSMEG_5178|M.smegmatis_MC2_155 GRVITAAALLMSISFAALIAAQVAFMRMFGLGLTLAVLVDATLVRMLLVP TH_1538|M.thermoresistible__bu ARVITAAALIMSISFAALIGAQVSFMRMIGLGLMVAVLVDATLVRLILVP MAB_1287|M.abscessus_ATCC_1997 GRVVTAAALIMAIAFAALMAAQVSFMRMFGTGLTIAILVDATIIRMLLVP MLBr_02620|M.leprae_Br4923 GRLITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP Rv1145|M.tuberculosis_H37Rv -------------------------------------------------- Mb1177|M.bovis_AF2122/97 AFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRSHAGG-----LGK MAV_1287|M.avium_104 AFMHVMGRWNWWAPKPLAWLHDRFGISEAADEEPRLRACPRTRRIRRIAR MMAR_4305|M.marinum_M AFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGDADAAATEA-------- MUL_0989|M.ulcerans_Agy99 AFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGGADAAATEA-------- Mflv_2131|M.gilvum_PYR-GCK AFMHLLGRWNWWAPPPLARLHARIGVSETVP------------------- Mvan_4573|M.vanbaalenii_PYR-1 AFMHVLGRWNWWAPKPLARLHERIGFSETLDDSSDSPP------------ MSMEG_5178|M.smegmatis_MC2_155 AFMRVMGRWNWWAPAPLARLHERIGFSESGLPPDPKP------------- TH_1538|M.thermoresistible__bu AFMHVMGRANWWAPAPLARWHDRFGIREAADAPDRPRSDPAPTPX----X MAB_1287|M.abscessus_ATCC_1997 SFMRLLGRFNWWAPKPLVTLHERIGFSD---------------------- MLBr_02620|M.leprae_Br4923 SVMKLLGDDCWWAPRWARLLQNRIGLGEIHLPDERRRPTVSGRPVRPPVT Rv1145|M.tuberculosis_H37Rv -------------------------------------------------- Mb1177|M.bovis_AF2122/97 IAGRSDGQTIPASLTRNG-------------------------------- MAV_1287|M.avium_104 RRGRRTGAQHRLTAVRPTARRVWRSDPILRLIRGGRCTQA---------- MMAR_4305|M.marinum_M -ADRRDRPTIPAALSGRG-------------------------------- MUL_0989|M.ulcerans_Agy99 -ADRRDRPTIPAALSGRG-------------------------------- Mflv_2131|M.gilvum_PYR-GCK -------QRV---------------------------------------- Mvan_4573|M.vanbaalenii_PYR-1 ----RSRQHVATGNEHG--------------------------------- MSMEG_5178|M.smegmatis_MC2_155 -------QPASVGMTQSG-------------------------------- TH_1538|M.thermoresistible__bu XDASVRKGPAPSSISRDPAVPAYVPDRPRTRSACRCSR------------ MAB_1287|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02620|M.leprae_Br4923 AASLAAPASRVPRGPTHPATLEPSQRARSGLASRPQIKRPQELPSGASTA Rv1145|M.tuberculosis_H37Rv -------------------------------------------------- Mb1177|M.bovis_AF2122/97 -------------------------------------------------- MAV_1287|M.avium_104 -------------------------------------------------- MMAR_4305|M.marinum_M -------------------------------------------------- MUL_0989|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4573|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5178|M.smegmatis_MC2_155 -------------------------------------------------- TH_1538|M.thermoresistible__bu -------------------------------------------------- MAB_1287|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02620|M.leprae_Br4923 RIQMRPSQSVEATTTRLSVPGNAPTTAAVSSSQGVQAVPLAATRHPLPTP Rv1145|M.tuberculosis_H37Rv -------------------------------------------------- Mb1177|M.bovis_AF2122/97 -------------------------------------------------- MAV_1287|M.avium_104 -------------------------------------------------- MMAR_4305|M.marinum_M -------------------------------------------------- MUL_0989|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4573|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5178|M.smegmatis_MC2_155 -------------------------------------------------- TH_1538|M.thermoresistible__bu -------------------------------------------------- MAB_1287|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02620|M.leprae_Br4923 SPASGQTRAMPVPANRSSDNASETAEPTTALPIMRPQDNDSEVATEKLNA Rv1145|M.tuberculosis_H37Rv ------------------------------ Mb1177|M.bovis_AF2122/97 ------------------------------ MAV_1287|M.avium_104 ------------------------------ MMAR_4305|M.marinum_M ------------------------------ MUL_0989|M.ulcerans_Agy99 ------------------------------ Mflv_2131|M.gilvum_PYR-GCK ------------------------------ Mvan_4573|M.vanbaalenii_PYR-1 ------------------------------ MSMEG_5178|M.smegmatis_MC2_155 ------------------------------ TH_1538|M.thermoresistible__bu ------------------------------ MAB_1287|M.abscessus_ATCC_1997 ------------------------------ MLBr_02620|M.leprae_Br4923 LGQGDNSRQHRRATGGGISAQDLLRREGRL