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SYMIAVPDMLSSAAGDLASIGSSINASTRAAAAATTRLLPAAADEVSAHIAALFSGHGEGYQAIARQMAA FHDQFTLALTSSAGAYASAEATNVEQQVLGLINAPTQALLGRPLIGNGADGTAANPNGGAGGLLYGNGGN GFSQTTAGLTGGTGGSAGLIGNGGNGGAGGAGANGGAGGNGGWLYGSGGNGGAGGAGPAGAIGAPGVAGG AGGAGGTAGLFGNGGAGGAGGAGGAGGRGGDGGSAGWLSGNGGDAGTGGGGGNAGNGGNGGSAGWLSGNG GTGGGGGTAGAGGQGGNGNSGIDPGNGGQGADTGNAGNGGHGGSAAKLFGDGGAGGAGGMGSTGGTGGGG GFGGGTGGNGGNGHAGGAGGSGGTAGLLGSGGSGGTGGDGGNGGLGAGSGAKGNGGNGGDGGKGGDAQLI GNGGNGGNGGKGGTGLMPGINGTGGAGGSRGQISGNPGTPGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1068c | PE_PGRS20 | - | 100% (463) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1067c | PE_PGRS19 | e-167 | 60.04% (528) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv1396c | PE_PGRS25 | e-148 | 56.40% (516) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1097c | PE_PGRS20 | 0.0 | 69.57% (539) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 6e-91 | 50.52% (382) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 7e-14 | 42.39% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 6e-47 | 38.59% (355) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_0572 | - | 1e-145 | 55.29% (501) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 1e-21 | 42.94% (170) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-80 | 43.55% (434) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 8e-46 | 43.31% (284) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4399 | - | 1e-135 | 52.85% (492) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-90 | 42.89% (485) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0572|M.marinum_M --------------------------------------------------
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0572|M.marinum_M --------------------------------------------------
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0572|M.marinum_M --------------------------------------------------
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0572|M.marinum_M --------------------------------------------------
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 -----------------------------------------MNIVLGVSM
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0572|M.marinum_M --------------------------------------------------
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 APSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILG-T
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
Rv1068c|M.tuberculosis_H37Rv ------------------------------------MS-YMIAVPDMLSS
Mb1097c|M.bovis_AF2122/97 ------------------------------------MS-YMIAVPDMLSS
MMAR_0572|M.marinum_M ------------------------------------MS-FVVVVPEMLSM
MUL_4399|M.ulcerans_Agy99 ------------------------------------MS-YLLVAPELLTS
MLBr_01183|M.leprae_Br4923 ------------------------------------MPLFLNAEPQALTA
MAB_4284c|M.abscessus_ATCC_199 ---MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPV
MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
Rv1068c|M.tuberculosis_H37Rv AAGDLASIGSSINASTRAAAAATTRLLPAAADEVSAHIAALFSGHGEGYQ
Mb1097c|M.bovis_AF2122/97 AAGDLASIGSSINASTRAAAAATTRLLPAAADEVSAHIAALFSGHGEGYQ
MMAR_0572|M.marinum_M AATDLASVGSAVSAANTAAAAPTTSVLAAAGDEVSAAVAALFSDHAHNYQ
MUL_4399|M.ulcerans_Agy99 AATDLEGIASALSTANLAAAVPTTGMLAAGADEVSAAVASLFAGYGQAYQ
MLBr_01183|M.leprae_Br4923 AANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQ
MAB_4284c|M.abscessus_ATCC_199 VAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSP
MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYG
. .
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
Rv1068c|M.tuberculosis_H37Rv AIARQMAAFHDQFTLALTSSAGAYASAEATN------------------V
Mb1097c|M.bovis_AF2122/97 AIARQMAAFHDQFTLALTSSAGAYASAEATN------------------V
MMAR_0572|M.marinum_M ALGRQAAAFHDQFVAALSAGGGGYGAAETAN------------------V
MUL_4399|M.ulcerans_Agy99 SISLQANAFQAQFIQAINGAGGAYVAAEAASTSPLQA------------F
MLBr_01183|M.leprae_Br4923 AHASQGATNHQDLIQSLLTSSSAYAGTETAN-------------------
MAB_4284c|M.abscessus_ATCC_199 RDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQF
MAV_4827|M.avium_104 DAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVA
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu NGYRTTDNNALDGGHGG---------------------------------
Rv1068c|M.tuberculosis_H37Rv EQQVLGLINAPTQALLGRPLIGNGADGTAANPNGGAG-------------
Mb1097c|M.bovis_AF2122/97 EQQVLGLINAPTQALWGRPLIGNGADGTAANPNGGAG-------------
MMAR_0572|M.marinum_M QQSLLNLINGPTQALLGRPLIGNGADGTAPGQAGGAG-------------
MUL_4399|M.ulcerans_Agy99 EDTVLGVINAPTQTLLGRPLIGDGAAGTVANPNGGAG-------------
MLBr_01183|M.leprae_Br4923 HDSL----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVR-------------
MAV_4827|M.avium_104 EEPETALARGAALAAANAPLFASSTAALAYAQDPGTG-------------
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu ------------------------------------------NGGNVGFF
Rv1068c|M.tuberculosis_H37Rv ---------------------------------------GLLYGNGGNGF
Mb1097c|M.bovis_AF2122/97 ---------------------------------------GLLYGNGGNGF
MMAR_0572|M.marinum_M ---------------------------------------GLLYGNGGNGA
MUL_4399|M.ulcerans_Agy99 ---------------------------------------GFLYGNGGNGF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------DSNIINADHGSN
MAV_4827|M.avium_104 ----------------------------------------AVDQYSLPDY
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu SLFNLGG--------------------AGGWGGSGVDG------------
Rv1068c|M.tuberculosis_H37Rv SQTTAGLTGGTGG-------------SAGLIGNGGNGGAGGAGAN-----
Mb1097c|M.bovis_AF2122/97 SQTTAGLTGGTGG-------------SAGLIGNGGNGGAGGAGAN-----
MMAR_0572|M.marinum_M PGANPGVAGGAGG-------------AAGLIGNGGAGGSGGAGAAASGSG
MUL_4399|M.ulcerans_Agy99 SQTTAGVAGGAGG-------------AAGLIGNGGMGGAGGAGAA-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGVDQSQTRVGGDYTN-----------VSGHGSADIDKSVTVVDDHSQRN
MAV_4827|M.avium_104 LYVPVDPEPGDDE------------LAYSAVGEEDAESPTVVIEKLFLPE
Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu ---------VDVVGGNP---------------------------------
Rv1068c|M.tuberculosis_H37Rv -------GGAGGNGGWLYGSGGNGGAGGAG-----------------PAG
Mb1097c|M.bovis_AF2122/97 -------GGAGGNGGWLYGSGGNGGAGGAG-----------------PAG
MMAR_0572|M.marinum_M DGGDGGAGGAGGSGGWLYGTGGAGGSGGAG-----------------GVS
MUL_4399|M.ulcerans_Agy99 -------GGAGGTGGWWFGNGGVGGAGGAG-----------------TAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TTNINDSFNTDRSTNIGSGNTTNTEIGSHN--------------------
MAV_4827|M.avium_104 DSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTG--------TVA
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu ---------DGGTPG------------------------------AHGES
Rv1068c|M.tuberculosis_H37Rv --AIGAPGVAGGAGGAGGTAGLFGN-------------------GGAGGA
Mb1097c|M.bovis_AF2122/97 --AIGAPGVAGGAGGAGGSAGLFGN-------------------GGAGGA
MMAR_0572|M.marinum_M GMNPGNHGGLGGNGGAGGAAGIVGE-------------------GGAGGA
MUL_4399|M.ulcerans_Agy99 --AVGFNGVSGGAGGAGGAAGWWGA-------------------GGAGGQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 QANIGTSTSAGGSAAVGGNAGLAGN------------------AGLAGNA
MAV_4827|M.avium_104 LQPTPNQHLIVPTEQAPAPPPVQAS-------------------APQPKI
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu HTPGVYTDRQ----------------------------------------
Rv1068c|M.tuberculosis_H37Rv G-------------------------------------------------
Mb1097c|M.bovis_AF2122/97 GGAGGQGGAGIGGADGTKGGDAGAGGAGGAGGWIHGHGGVGGDGGTGGQG
MMAR_0572|M.marinum_M GGMGG---------------------------------------------
MUL_4399|M.ulcerans_Agy99 GGTGGMAG------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAG----------------------------------------
MAV_4827|M.avium_104 SVPEPVAAPKPLSP------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu ---------------GEDGEDGTGTGIGGRGGNGG---------------
Rv1068c|M.tuberculosis_H37Rv ---------------GAGGAGGRGGDGGSAGWLSG---------------
Mb1097c|M.bovis_AF2122/97 GDGVQGEPGDTGAAGGAGGAGGRGGDGGSAGWLSG---------------
MMAR_0572|M.marinum_M -------SGFTSAVTTAGGNGGNGGTGGGGGLLAG---------------
MUL_4399|M.ulcerans_Agy99 -----GYDNVNGVFGITAGNGGDGGAGGRGGWLFG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------NAGLAGNAGLAGNAGLAGNAGLAGN---------------
MAV_4827|M.avium_104 ----------PVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVP
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGS------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGS------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGG------------------------------------
TH_3810|M.thermoresistible__bu -SSSGTHPMAEDG-------------------------------------
Rv1068c|M.tuberculosis_H37Rv --NGGDAGTGGGGG------------------------------------
Mb1097c|M.bovis_AF2122/97 --NGGDAGTGGGGGNAGAGGEGGIFGGNGGNGGTGGTAGGGGNGGRGAAL
MMAR_0572|M.marinum_M --NAGAGGAGGDGG------------------------------------
MUL_4399|M.ulcerans_Agy99 --DAGAGGQGGLGG------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAG------------------------------------
MAV_4827|M.avium_104 VPVPVRIPVPDPVS------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 FGHGGNAGHGGAGGNGAAGGNGADTQLGISGKGGTGGGGGGAGAGGTGGD
MMAR_0572|M.marinum_M --------------------------------------------------
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 GGLLYGNGGAGGNGGNGGAAGKGGIGAPGLSTAQGGDGGNGGSGGNAGNG
MMAR_0572|M.marinum_M --------------------------------------------------
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 GNGGRGSVLFGHGGNAGHGGAGGNGAVSGNGGSSITAVGGKGGTGGGGGG
MMAR_0572|M.marinum_M --------------------------------------------------
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 GAGGTGGDAGLLYGNGGAGGTGGSGGAGARGGDGGAGSGTAQGGDGGAGG
MMAR_0572|M.marinum_M --------------------------------------------------
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGTGGTGGTGGTGGTG---GTGGTGGTGGTGGKGGTGGTGGA
Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGTGGTGGTGGTGGTG---GTGGTGGTGGTGGKGGTGGTGGD
MSMEG_0868|M.smegmatis_MC2_155 ----TFVNAGANGNGGAGGAGGVSE--GEGGTGGHGGDGGRGGDGALGGN
TH_3810|M.thermoresistible__bu -----------EHVKALDGRPGLD-----GGNGSHGGNGGHGGRGGFLGI
Rv1068c|M.tuberculosis_H37Rv ---NAGNGGNGGSAGWLSGNGGTG---GGGGTAGAGGQGGNGNSGIDPGN
Mb1097c|M.bovis_AF2122/97 VGGNAGNGGNGGSAGWLSGNGGTG---GGGGTAGAGGQGGNGNSGIDPGN
MMAR_0572|M.marinum_M -----------GPVGDLGGNGGIG---GDGGAAGLFGNGGAGGAGGGGGA
MUL_4399|M.ulcerans_Agy99 -------DGNYAGQGSYGGVGGAG---GAGGAAGMFGSGGSGGAGGEGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGN
MAV_4827|M.avium_104 -------PPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQ
Mflv_5091|M.gilvum_PYR-GCK GGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGGAG------
Mvan_1264|M.vanbaalenii_PYR-1 GGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGGAG------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNN
TH_3810|M.thermoresistible__bu GGSG-------GWGGHGGNGGD-----------TDADGGNGGDG------
Rv1068c|M.tuberculosis_H37Rv GGQG----ADTGNAGNGGHGGSAA-----KLFGDGGAGGAGGMG------
Mb1097c|M.bovis_AF2122/97 GGQG----ADTGNAGNGGHGGSAA-----KLFGDGGAGGAGGMG------
MMAR_0572|M.marinum_M APVS----GAAAAGGAGGGGGAGG-----LLYGDGGLGGAGGAGG-----
MUL_4399|M.ulcerans_Agy99 FGDGNA--GGSGSGGHGGNGGNGG-----WLYGDAGAGGQGGNA------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGLAG----NAGLAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGG-----
MAV_4827|M.avium_104 TPPGEG--TPPKPDGPGNYGGGHVP--------TPGAGGSGGSGG-----
Mflv_5091|M.gilvum_PYR-GCK -----DGTGGTGGTGG----TGGQGGQGGQGG-----------------T
Mvan_1264|M.vanbaalenii_PYR-1 -----DGLGGTGGTGG----TGGFGGQGGQGG-----------------T
MSMEG_0868|M.smegmatis_MC2_155 GTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTAT
TH_3810|M.thermoresistible__bu ---------GNGGSAG---------------------------------R
Rv1068c|M.tuberculosis_H37Rv ------STGGTGGGGGFGGGTGGNGGNGHAGG-----------------A
Mb1097c|M.bovis_AF2122/97 ------STGGTGGGGGFGGGTGGNGGNGHAGG-----------------A
MMAR_0572|M.marinum_M -EALDGGVGGSGGAGGHGGGGGLLYGNGGSGG-----------------A
MUL_4399|M.ulcerans_Agy99 ----------APGAYSDNLGTFQSSYTSGNGG-----------------A
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----VLNTGVSGAIGGSSHVGGAINESLGGSG----------------SV
MAV_4827|M.avium_104 ------GHVPTPGAGGSGGSGGGHVPTPGTGG-----------------P
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGG-LGGGGGTG-----------------------GQGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGG-LGGVGGTG-----------------------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGG
TH_3810|M.thermoresistible__bu GGTGGLRGVFGINGGNG------------------------RAGLGGRGX
Rv1068c|M.tuberculosis_H37Rv GGSGGTAG-LLGSGGSG-----------------------GTGGDGGNGG
Mb1097c|M.bovis_AF2122/97 GGSGGTAG-LLGSGG--------------------------TGGDGGNGG
MMAR_0572|M.marinum_M GGKGGVAAGIFDRGGTG-----------------------GTGGNGGVGG
MUL_4399|M.ulcerans_Agy99 GGNGGVAG-MIGTGGAG-----------------------GAGGAGGVNA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSTAVGGGAHTGVGGG------------------------VSTGVGVGS
MAV_4827|M.avium_104 GGTGGSGGGHVPTPGAG-----------------------TPGGSGGGHL
Mflv_5091|M.gilvum_PYR-GCK QGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGSGGTGGQGG
Mvan_1264|M.vanbaalenii_PYR-1 QGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGVGGTGGQGG
MSMEG_0868|M.smegmatis_MC2_155 HGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTAN
TH_3810|M.thermoresistible__bu XXXGGGVGAAVRSG---------------NGVFSGGGGTPSAGFGVPTTI
Rv1068c|M.tuberculosis_H37Rv LGAGSGAKGNGGN-------GGDGGKGGDA-QLIGNGGNGGNGGKGGTGL
Mb1097c|M.bovis_AF2122/97 LGAGSGAKGNGGN-------GGDGGKGGDA-QLIGNGGNGGNGGKGGTGL
MMAR_0572|M.marinum_M LLYGNGGRGGAGGDGANLAGGGNGGNGGDT-RLIGNGGDGGHGGSG----
MUL_4399|M.ulcerans_Agy99 FDSGGGG-GGGGN-------GGNGGAGGASGALIEAGGVGGSGGGGGAGV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HVGGGISESLGGSG------SVGGSTAVGGGAHTGVGGGVSTGVGVGSHV
MAV_4827|M.avium_104 PFPGAGSTPGGSGGGHLPTPGAGTPGGGLGGFGGGHAPAPGGGLGGGGGH
Mflv_5091|M.gilvum_PYR-GCK LGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGA
Mvan_1264|M.vanbaalenii_PYR-1 QGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGA
MSMEG_0868|M.smegmatis_MC2_155 AANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTA
TH_3810|M.thermoresistible__bu QFPAGSCTSRAVSREG------------------------IMPSSRAASA
Rv1068c|M.tuberculosis_H37Rv MPGINGTGGAGGSRGQISGNPGTPGQ------------------------
Mb1097c|M.bovis_AF2122/97 MPGINGTGGAGGSRGQISGNPGTPGQ------------------------
MMAR_0572|M.marinum_M -ALVGGAGGSGGIGGRLFGQAGAAG-------------------------
MUL_4399|M.ulcerans_Agy99 VGPPAGNPGNDGLDG-VTGASGLLFGG-----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGGISESLGGSGSVGGSTAVGGGAHTGVGGGVNTGVGVGSHVGGGISESL
MAV_4827|M.avium_104 APAPGGGLGGFGGGHSGGGLGGLGGGHK----------------------
Mflv_5091|M.gilvum_PYR-GCK SGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAA
Mvan_1264|M.vanbaalenii_PYR-1 SGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAGSAGSAGVA
MSMEG_0868|M.smegmatis_MC2_155 TAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGAT
TH_3810|M.thermoresistible__bu RAG---------------------------AACASSTSRSRRSFCCSRA-
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0572|M.marinum_M --------------------------------------------------
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGSTAVGGGAHTSAINDALGGSGSVGGSTAVGGGAHTSAINESM
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGA
Mvan_1264|M.vanbaalenii_PYR-1 GSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGA
MSMEG_0868|M.smegmatis_MC2_155 GGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGP
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0572|M.marinum_M --------------------------------------------------
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPG
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TG--------AAGEDGDAGSGGSG-INGGAGGAGG-----------AGGE
Mvan_1264|M.vanbaalenii_PYR-1 TG--------AAGDAGDPGSEAVD-INGGAGGAGG-----------AGGE
MSMEG_0868|M.smegmatis_MC2_155 VGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGE
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0572|M.marinum_M --------------------------------------------------
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AEHH----------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGG
Mvan_1264|M.vanbaalenii_PYR-1 GGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGG
MSMEG_0868|M.smegmatis_MC2_155 HNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0572|M.marinum_M --------------------------------------------------
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK SGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 SGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 NGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu -------------------
Rv1068c|M.tuberculosis_H37Rv -------------------
Mb1097c|M.bovis_AF2122/97 -------------------
MMAR_0572|M.marinum_M -------------------
MUL_4399|M.ulcerans_Agy99 -------------------
MLBr_01183|M.leprae_Br4923 -------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------
MAV_4827|M.avium_104 -------------------