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MSFVVVVPEMLSMAATDLASVGSAVSAANTAAAAPTTSVLAAAGDEVSAAVAALFSDHAHNYQALGRQAA AFHDQFVAALSAGGGGYGAAETANVQQSLLNLINGPTQALLGRPLIGNGADGTAPGQAGGAGGLLYGNGG NGAPGANPGVAGGAGGAAGLIGNGGAGGSGGAGAAASGSGDGGDGGAGGAGGSGGWLYGTGGAGGSGGAG GVSGMNPGNHGGLGGNGGAGGAAGIVGEGGAGGAGGMGGSGFTSAVTTAGGNGGNGGTGGGGGLLAGNAG AGGAGGDGGGPVGDLGGNGGIGGDGGAAGLFGNGGAGGAGGGGGAAPVSGAAAAGGAGGGGGAGGLLYGD GGLGGAGGAGGEALDGGVGGSGGAGGHGGGGGLLYGNGGSGGAGGKGGVAAGIFDRGGTGGTGGNGGVGG LLYGNGGRGGAGGDGANLAGGGNGGNGGDTRLIGNGGDGGHGGSGALVGGAGGSGGIGGRLFGQAGAAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0572 | - | - | 100% (489) | PE-PGRS family protein |
| M. marinum M | MMAR_1207 | - | e-161 | 58.41% (541) | PE-PGRS family protein |
| M. marinum M | MMAR_1208 | - | e-158 | 52.48% (625) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0545 | PE_PGRS6a | 1e-153 | 54.56% (592) | hypothetical protein Mb0545 |
| M. gilvum PYR-GCK | Mflv_5091 | - | 7e-90 | 44.53% (503) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1396c | PE_PGRS25 | 1e-154 | 54.51% (576) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-11 | 36.96% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 5e-47 | 35.62% (365) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 8e-26 | 44.51% (173) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-74 | 41.72% (429) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 8e-44 | 41.86% (301) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3292 | - | 1e-141 | 49.10% (613) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 3e-90 | 44.24% (486) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MMAR_0572|M.marinum_M --------------------------------------------------
Mb0545|M.bovis_AF2122/97 --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Rv1396c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MMAR_0572|M.marinum_M --------------------------------------------------
Mb0545|M.bovis_AF2122/97 --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Rv1396c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MMAR_0572|M.marinum_M -----------------------------------------MS-FVVVVP
Mb0545|M.bovis_AF2122/97 -----------------------------------------MS-NLLVTP
MUL_3292|M.ulcerans_Agy99 -----------------------------------------MS-YVIAAP
Rv1396c|M.tuberculosis_H37Rv -----------------------------------------MS-FLFAQP
MLBr_01183|M.leprae_Br4923 -----------------------------------------MPLFLNAEP
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104 -------------------------------------MNIVLGVSMAPSS
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MMAR_0572|M.marinum_M ----------------------------------------EMLSMAATDL
Mb0545|M.bovis_AF2122/97 ----------------------------------------ELVAAAAADL
MUL_3292|M.ulcerans_Agy99 ----------------------------------------EMLAGAATDL
Rv1396c|M.tuberculosis_H37Rv ----------------------------------------EMLGAAATDL
MLBr_01183|M.leprae_Br4923 ----------------------------------------QALTAAANTL
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------VEAASYVADPEAAL
MAV_4827|M.avium_104 -------------------------------------IQMVVLEGEYADG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MMAR_0572|M.marinum_M AS----------------------VGSAVS-----------AANTAAAAP
Mb0545|M.bovis_AF2122/97 AG----------------------IGSAIG-----------AANAAAGAP
MUL_3292|M.ulcerans_Agy99 AG----------------------IGAALQ-----------SANGAAAAP
Rv1396c|M.tuberculosis_H37Rv AS----------------------IGSAIS-----------TANAAAAAA
MLBr_01183|M.leprae_Br4923 EG----------------------LSAATV-----------ASNAAAAQL
MAB_4284c|M.abscessus_ATCC_199 ANAG----------------LSAVSAAQVG---------AVMPVVAESVA
MAV_4827|M.avium_104 AT---------------------VEEDAID-----------VTGADDAAT
TH_3810|M.thermoresistible__bu ----------VDGDGGSGGRTGLFSKLSRGGDGGDGGLGGNGGHGGGTGI
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDG--GNGGNGGLFGGNGGNGGNGL
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSG--GNGGNAGLFGGNGGNGGNGL
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAG--GNGGNAGLFG-NGGNGGVGW
MMAR_0572|M.marinum_M TTS-------VLAAAGDEVSAAVAALFS--DHAHNYQALGRQAAAFHDQF
Mb0545|M.bovis_AF2122/97 TMA-------LLAAGADEVSAAVAAVFS--SYAQQYQALSAAAAAFHDQF
MUL_3292|M.ulcerans_Agy99 ITG-------VLAAGADEISAAVAALFS--GHALDYQALSTQMAGFHQQF
Rv1396c|M.tuberculosis_H37Rv TTR-------VLAAGADEVSAAVAALFS--GHAQTYQALRTQAAAFHQQI
MLBr_01183|M.leprae_Br4923 TTE-------IAPPAADDVSILLAHFFS--GHGRQYQAHASQGATNHQDL
MAB_4284c|M.abscessus_ATCC_199 SNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFL
MAV_4827|M.avium_104 ASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRI
TH_3810|M.thermoresistible__bu IS-------------LLSLAGNGGNGGNGYR----TTDNNALDGGHGGNG
Mflv_5091|M.gilvum_PYR-GCK GGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGA
Mvan_1264|M.vanbaalenii_PYR-1 GSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGA
MSMEG_0868|M.smegmatis_MC2_155 AGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGG
MMAR_0572|M.marinum_M VA------------ALSAGGGGYGAAETAN------VQQSLLNLINGPTQ
Mb0545|M.bovis_AF2122/97 VR------------ALAAGAGAYAGAEAAN------VEQQLLNAINAPTL
MUL_3292|M.ulcerans_Agy99 VT------------ALNSAGASYAAAEAASANPLQAVEQQLLGVINAPTQ
Rv1396c|M.tuberculosis_H37Rv VQ------------TLTSTAGAYASAEAAN------VEQQLLGAINAPTM
MLBr_01183|M.leprae_Br4923 IQ------------SLLTSSSAYAGTETAN------HDSL----------
MAB_4284c|M.abscessus_ATCC_199 SHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTT
MAV_4827|M.avium_104 DNVMLVSAFLAAAALAQNVGGAMGYERTAVL--LVEPDTATLAVVETSDG
. .
TH_3810|M.thermoresistible__bu GNVG---------------FFSLFNLGGAGGWGGSG--------------
Mflv_5091|M.gilvum_PYR-GCK TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1 TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155 TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPN
MMAR_0572|M.marinum_M ALLGRPLIG-----------NGADGTA-PGQAGGAGG-------------
Mb0545|M.bovis_AF2122/97 ALLGRPLIG-----------NGADGAAGTGQAGGAGG-------------
MUL_3292|M.ulcerans_Agy99 ALLGRPLIG-----------DGTAGAP--GQNGGDGG-------------
Rv1396c|M.tuberculosis_H37Rv ALLGRPLIG-----------HGADGAPGTGQAGGAGG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIIN-------------
MAV_4827|M.avium_104 SIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGG-----------L
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155 VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
MMAR_0572|M.marinum_M LLYGNGGNGAPGANPGVAG-------GAGGAAGLIG--------------
Mb0545|M.bovis_AF2122/97 LLYGNGGNGGSGA-AGQAG-------GAGGAAGLIG--------------
MUL_3292|M.ulcerans_Agy99 LLWGNGGAGGVGTAAHPTG-------GSGGSAGLIG--------------
Rv1396c|M.tuberculosis_H37Rv ILYGNGGNGGSGA-TGQAG-------GAGGAAGLIG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --ADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKS--------------
MAV_4827|M.avium_104 LLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETALAR--------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG------TVGTAGATGGTG---------------TGANGG
Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG------AAGTAGATGGTG---------------VGGNGG
MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG
MMAR_0572|M.marinum_M ---------------------NGGAGGSG---------------------
Mb0545|M.bovis_AF2122/97 ---------------------HGGTGGVG---------------------
MUL_3292|M.ulcerans_Agy99 ---------------------TGGAGGAGY--------------------
Rv1396c|M.tuberculosis_H37Rv ---------------------HGGAGGLG---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------VTVVDDHSQRNTTNIN-------------------
MAV_4827|M.avium_104 ---------------------GAALAAAN---------------------
TH_3810|M.thermoresistible__bu -----------------------------------------VDGVDVVGG
Mflv_5091|M.gilvum_PYR-GCK AGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGG
Mvan_1264|M.vanbaalenii_PYR-1 AGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGG
MSMEG_0868|M.smegmatis_MC2_155 HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGE
MMAR_0572|M.marinum_M --------GAGAAA----------------SGSGDG----GDGGAGGAGG
Mb0545|M.bovis_AF2122/97 --------GTGAAG----------------GAGGTGGWLFGNGGAGGTGG
MUL_3292|M.ulcerans_Agy99 --------GPAAQT----------------GATGGSGGVGGTGGSGLDGP
Rv1396c|M.tuberculosis_H37Rv --------GTGASG----------------GAGGAGGWLWGNGGAGGNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----DSFNTDRSTN--------------IGSGNTTNTEIGSHNQANIGT
MAV_4827|M.avium_104 -------APLFASS----------------TAALAYAQDPGTGAVDQYSL
TH_3810|M.thermoresistible__bu N-------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1 Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG
MMAR_0572|M.marinum_M S-------------------------------------------------
Mb0545|M.bovis_AF2122/97 A-------------------------------------------------
MUL_3292|M.ulcerans_Agy99 D-------------------------------------------------
Rv1396c|M.tuberculosis_H37Rv VG------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 S-------------------------------------------------
MAV_4827|M.avium_104 P-------------------------------------------------
TH_3810|M.thermoresistible__bu -------PDGGTPGAHGESHTPGVYTD-----------------------
Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG
Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG
MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG
MMAR_0572|M.marinum_M -----GGWLYGTGGAGGSGGAGGVSGMN-----------------PGNHG
Mb0545|M.bovis_AF2122/97 -----VTGVSTTGGPGGHGGDAGLYGFGG----------------AGGAG
MUL_3292|M.ulcerans_Agy99 -----SGAAGGAGGSGGSGGAARLFGNGG----------------AGGSG
Rv1396c|M.tuberculosis_H37Rv ----VAGDPGGVGGAGGAGGAAGLWGSGG----------------SGGTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---TSAGGSAAVGGNAGLAGNAGLAGNAG----------------LAGNA
MAV_4827|M.avium_104 ----DYLYVPVDPEPGDDELAYSAVGEED----------------AESPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GKGGNGGNGGRGGLFG---------------KGGNAGNGAD---------
Mvan_1264|M.vanbaalenii_PYR-1 GKGGNGGNGGRGSLFG---------------RGGNAGNGGN---------
MSMEG_0868|M.smegmatis_MC2_155 AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN
MMAR_0572|M.marinum_M GLGGNGG-------------------------------------------
Mb0545|M.bovis_AF2122/97 GFGQSGA-------------------------------------------
MUL_3292|M.ulcerans_Agy99 GKGGNGGSAI-E--------------------------------------
Rv1396c|M.tuberculosis_H37Rv GQGGVGGGKSGD--------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAG-------------------------------------------
MAV_4827|M.avium_104 VVIEKLFLPEDS--------------------------------------
TH_3810|M.thermoresistible__bu ---------------RQGEDGEDGTGTGIGGRGGNGG-------------
Mflv_5091|M.gilvum_PYR-GCK -------------GGTGGAGGAGGTGG-TGGAGGTGG-------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------GGTGGNGGNGGTGG-TGGNGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155 GPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST
MMAR_0572|M.marinum_M ---------------AGGAAGIVGEG----GAGGAGG-------------
Mb0545|M.bovis_AF2122/97 ---------------AGGAGGAGGAGGWLYGDGGDGG-------------
MUL_3292|M.ulcerans_Agy99 -------------TGNDGAAGAGGHGGWLVGNGGIGG-------------
Rv1396c|M.tuberculosis_H37Rv -------------GGTGGIGGAGGGGGWLHGDGGAGG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------LAGNAGLAGNAGLAGNAGLAGN-------------
MAV_4827|M.avium_104 -------------EPRRRPVLLVGSGLAVVGISAVLALEIA---------
TH_3810|M.thermoresistible__bu ------------------------SSSGTHPMAEDGEHVKALDGRPGLDG
Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGIGGA------GSTGGTGGTGGTGGTGGTGGTG-GTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGIGGA------GSTGGTGGTGGTGGTGGTGGTG-GTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GQTDTGGNGGRGGD------GGTFVNAGANGNGGAGGAGGVSEGEGGTGG
MMAR_0572|M.marinum_M ----MGGSGFT---------SAVTTAGGNGGNGGTGGGGGLLAGNAGAGG
Mb0545|M.bovis_AF2122/97 ----AGGNGGN---------ESGTGVSGVGGVGGAGGAGGLLFGNGGDGG
MUL_3292|M.ulcerans_Agy99 ----DGGSGGVGGDAGAYGPPANGGAGGHGGMGGVGGDAGLLFGSGGAGG
Rv1396c|M.tuberculosis_H37Rv ----HGGQGGT-----------GVSSGGNGGAGGTGGDGRGLSGSGGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------AGLAGNAGLAGNAGLAGNAGLAGNAGLAGN
MAV_4827|M.avium_104 -------------------LAIGIRTTGTVALQPTPNQHLIVPTEQAPAP
TH_3810|M.thermoresistible__bu ------------------------GNGSHGGNGGHGGRG---------GF
Mflv_5091|M.gilvum_PYR-GCK TGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GT
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GT
MSMEG_0868|M.smegmatis_MC2_155 HGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGA
MMAR_0572|M.marinum_M AGGDGG----------GPVGDLG-GNGGIGGDGGAAG------------L
Mb0545|M.bovis_AF2122/97 VGGDGGD--------GSSTQDSG-GDGGAGGAGGAGGW-----------L
MUL_3292|M.ulcerans_Agy99 VGGNGA---------IGGTGVMS-GAGGAGGDGGNGGYA---------QL
Rv1396c|M.tuberculosis_H37Rv RGGQTGVGGKVGENNFGGAGGAG-GTGGLIGNGGAGGNG---------GQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAGNAGLAG--NAGLAGNAGLAGNAG---------L
MAV_4827|M.avium_104 PPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAPPPAAP-------PL
TH_3810|M.thermoresistible__bu LGIGGSGGWG----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG--
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG--
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEA
MMAR_0572|M.marinum_M FGNGGAGGAGGG---------GGAAPVSG---------------------
Mb0545|M.bovis_AF2122/97 LGNGGAGGAGGA---------ASIKVATGGLGGDGGDAGLFGFGGDGG--
MUL_3292|M.ulcerans_Agy99 IGDGGGGGAGGAGYSASGLPPAGIGAPGGAGGAGGSGGWLVGNGGAGG--
Rv1396c|M.tuberculosis_H37Rv GAISGAGGAGGNAWLIGDGGAGGNGGDIRGQGGGAGGAGGAGGQLIGN--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGGVLNTGVSGAIGGSSHVG-
MAV_4827|M.avium_104 PEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLS--
TH_3810|M.thermoresistible__bu -----------------GHGGNGGDTDADGGNG-----------------
Mflv_5091|M.gilvum_PYR-GCK ---------------TGGTGGQGG-LGGGGGTG-----------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------TGGTGGQGG-LGGVGGTG-----------------
MSMEG_0868|M.smegmatis_MC2_155 LIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQA
MMAR_0572|M.marinum_M -------------------------AAAAGGAG-----------------
Mb0545|M.bovis_AF2122/97 ----------------WGGRGVDARFGAAGGAA-----------------
MUL_3292|M.ulcerans_Agy99 ----------------IGGIGASGSFGAPSGQG-----------------
Rv1396c|M.tuberculosis_H37Rv ----------------GGTGGAGGTVTSPNGLG-----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------GAINESLGGSGSVG-----------------
MAV_4827|M.avium_104 -----------------VPQPVQPPVRVPQPPS-----------------
TH_3810|M.thermoresistible__bu ------GDGGNGGSAGRGGTGGLR--------------GVFGINGGNGRA
Mflv_5091|M.gilvum_PYR-GCK ------GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLG
Mvan_1264|M.vanbaalenii_PYR-1 ------GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLG
MSMEG_0868|M.smegmatis_MC2_155 SGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDG
MMAR_0572|M.marinum_M ------GGGGAGG--LLYGDGGLG--------------GAGGAGGEALDG
Mb0545|M.bovis_AF2122/97 ------GAGGAGG--WLYGDGGAG--------------GVGGVGGAVFS-
MUL_3292|M.ulcerans_Agy99 ------GNGGIGGAAGLFGQGGAG--------------GNGGQGGGDDFA
Rv1396c|M.tuberculosis_H37Rv ------GAGGAGGSAGLIGHGGTG--------------GAGG-HSAQGPD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------GSTAVGGGAHTGVGGGVSTG-----------VGVGSHVGGGISE
MAV_4827|M.avium_104 --PPQVGGTVPQSPPQHQTPPGEG-------------TPPKPDGPGNYGG
TH_3810|M.thermoresistible__bu GLGGRGXXXXGGGVGAAVRSGNG---------------------------
Mflv_5091|M.gilvum_PYR-GCK GLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----
Mvan_1264|M.vanbaalenii_PYR-1 GLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----
MSMEG_0868|M.smegmatis_MC2_155 GLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWV
MMAR_0572|M.marinum_M GVGGSGGAGGHGGGGGLLYGNGGSGGAGGKGG------------------
Mb0545|M.bovis_AF2122/97 LSSGDGGAGGAGGGGGWLFGNGGDGGAGGGGGGRFGSGS-----------
MUL_3292|M.ulcerans_Agy99 LSGGAGGAGGAGGHGGQLYGDGGGGGAGGMGGSVDIAESG----------
Rv1396c|M.tuberculosis_H37Rv GNGGIGGAGGAGGNGGQLYGTGGTGGTGGKGG------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVG-------------
MAV_4827|M.avium_104 GHVPTPGAGGSGGSGGGHVPTPGAGGSGGSGG------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGA
Mvan_1264|M.vanbaalenii_PYR-1 GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGA
MSMEG_0868|M.smegmatis_MC2_155 QSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGN
MMAR_0572|M.marinum_M ------------VAAGIFDRGGTG--------------------------
Mb0545|M.bovis_AF2122/97 GAGGDGAVGGAGGAGAWFGNGGAGGVGGGGGRG-----------------
MUL_3292|M.ulcerans_Agy99 VTGGRGGSGSVGGGAGLWGAGGQGGDGAQGGDG-----------------
Rv1396c|M.tuberculosis_H37Rv ------------DGFGVFGKGGAG--------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -GGISESLGGSGSVGGSTAVGGGAHTGVGGGVN-----------------
MAV_4827|M.avium_104 ---------GHVPTPGTGGPGGTGGSGGGHVPTP----------------
TH_3810|M.thermoresistible__bu --------------------------------------------VFSGGG
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANG
Mvan_1264|M.vanbaalenii_PYR-1 SGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANG
MSMEG_0868|M.smegmatis_MC2_155 TATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNG
MMAR_0572|M.marinum_M -----------GTGGNGGVG----------------------GLLYGNGG
Mb0545|M.bovis_AF2122/97 ---TTAIGGDGGAGGAGGAG----------------------GWLYGDGG
MUL_3292|M.ulcerans_Agy99 ---GAGVDTTTGAGGDGGAGAG----------------GGTSGFLYGNGG
Rv1396c|M.tuberculosis_H37Rv -----------GTGGRGGAAG-----------------------LIGDAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --TGVGVGSHVGGGISESLGGS--------------------GSVGGSTA
MAV_4827|M.avium_104 -----------GAGTPGGSGGG--------------------HLPFPGAG
TH_3810|M.thermoresistible__bu GTPSAGFGVPTTIQFPAGS-------------------------------
Mflv_5091|M.gilvum_PYR-GCK SQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 SQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155 GKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNG
MMAR_0572|M.marinum_M RGGAGGDG-----ANLAG-------------------------GGNGGNG
Mb0545|M.bovis_AF2122/97 AGGAGGGGGRGGTGNDGGD------------------------GGDGGRG
MUL_3292|M.ulcerans_Agy99 AGGAGGHGGGG--PGMGGD------------------------GGDGGDG
Rv1396c|M.tuberculosis_H37Rv TGGTGGKGGTAGEDGTGGN------------------------GGTGGNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGAHTSAINDALGGSGS-----------------------VGGSTAVG
MAV_4827|M.avium_104 STPGGSGGGHLPTPGAGTP-----------------------GGGLGGFG
TH_3810|M.thermoresistible__bu -----------CTSRAVSREGIMPSSRAASAR--------AGAACASSTS
Mflv_5091|M.gilvum_PYR-GCK G-----------AGGEGGEGGDGGKGGAGAE---------GGAGGGGGAG
Mvan_1264|M.vanbaalenii_PYR-1 G-----------AGGEGGEGGAGGAGGDGSE---------GGAGGSGGAG
MSMEG_0868|M.smegmatis_MC2_155 GNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGG-NGAGGAGGNGGTG
MMAR_0572|M.marinum_M G-----------DTRLIGNGGDGGHGGSG--------ALVGGAGGSGGIG
Mb0545|M.bovis_AF2122/97 G-----------DAQLLGNGGDGGAGGAGGPAGFGASPGAGAAGGGGGAG
MUL_3292|M.ulcerans_Agy99 G-----------RAQLIGTGGNGGAGGTAAP------GGTDGTAGAAGKG
Rv1396c|M.tuberculosis_H37Rv G-----------AAVLIGNGGGGGAGGNGGAGNDGT-PGNGGGGGVGGTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GG---------AHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTG
MAV_4827|M.avium_104 G-----------GHAPAPGGGLGGGGGHAPAP--------GGGLGGFGGG
TH_3810|M.thermoresistible__bu RSRRSFCCSRA-------------------------
Mflv_5091|M.gilvum_PYR-GCK GSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
MMAR_0572|M.marinum_M GRLFGQAGAAG-------------------------
Mb0545|M.bovis_AF2122/97 GSLFGSPGTTGPHG----------------------
MUL_3292|M.ulcerans_Agy99 GVLFGTDGATG-------------------------
Rv1396c|M.tuberculosis_H37Rv GTLFGQPGQPGPPGQPGPA-----------------
MLBr_01183|M.leprae_Br4923 ------------------------------------
MAB_4284c|M.abscessus_ATCC_199 FEAQGHAQGHASETAHTTLPGAEHH-----------
MAV_4827|M.avium_104 HSGGGLGGLGGGHK----------------------