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TLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGIDVLGGLRGWL TAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAAELEQPVIETDSFTVDLAG KKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWGPAYATETHYLRVYLAQLRRKLEDDPSHP KHLLTESGMGYRFEA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1027c | kdpE | - | 100% (226) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN KDPE |
| M. tuberculosis H37Rv | Rv0491 | regX3 | 2e-41 | 39.38% (226) | two component sensory transduction protein RegX3 |
| M. tuberculosis H37Rv | Rv0903c | prrA | 2e-40 | 39.09% (220) | two component response transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1055c | kdpE | 1e-127 | 100.00% (226) | transcriptional regulatory protein KdpE |
| M. gilvum PYR-GCK | Mflv_0082 | - | 3e-42 | 40.09% (227) | two component transcriptional regulator |
| M. leprae Br4923 | MLBr_02123 | - | 5e-41 | 40.00% (220) | two-component response regulator |
| M. abscessus ATCC 19977 | MAB_3250c | - | 1e-98 | 77.33% (225) | transcriptional regulatory protein KdpE |
| M. marinum M | MMAR_0635 | kdpE | 1e-108 | 85.33% (225) | transcriptional regulatory protein KdpE |
| M. avium 104 | MAV_1169 | - | 1e-117 | 91.15% (226) | KDP operon transcriptional regulatory protein KdpE |
| M. smegmatis MC2 155 | MSMEG_5396 | - | 1e-107 | 85.78% (225) | KDP operon transcriptional regulatory protein KdpE |
| M. thermoresistible (build 8) | TH_4312 | - | 1e-41 | 38.77% (227) | PUTATIVE two component transcriptional regulator, winged helix |
| M. ulcerans Agy99 | MUL_4560 | regX3 | 2e-41 | 39.38% (226) | two component sensory transduction protein RegX3 |
| M. vanbaalenii PYR-1 | Mvan_4763 | - | 1e-106 | 83.93% (224) | two component transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1027c|M.tuberculosis_H37Rv ------MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEH
Mb1055c|M.bovis_AF2122/97 ------MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEH
MAV_1169|M.avium_104 ------MTRVLVIDDEPQILRALRINLSVRGYEVVTASTGAGALRAAAEH
MSMEG_5396|M.smegmatis_MC2_155 -MTAPIKTRVLVIDDEPQILRALRINLSVRGYEVRTAASGAEALHSAADH
Mvan_4763|M.vanbaalenii_PYR-1 -MTS-VKTRVLVIDDEPQILRALRINLSVRGYEVHTAASGAEALRMAADH
MMAR_0635|M.marinum_M ------MTRVLVIDDEPQILRALRINFSVRGYDVVTAATGAAALRAAAEQ
MAB_3250c|M.abscessus_ATCC_199 ------MTRVLVVDDEPQILRAMRINLSARGYEVVTASSGAGALRAAAET
MLBr_02123|M.leprae_Br4923 MDTGVSSPRVLVVDDDSDVLASLERGLRLSGFEVSTAIDGAEALRNATET
Mflv_0082|M.gilvum_PYR-GCK ------MTSVLIVEDEESLADPLAFLLRKEGFETTVVTDGPSALAEFERA
MUL_4560|M.ulcerans_Agy99 ------MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRS
TH_4312|M.thermoresistible__bu ------MTSVLIVEDEESLADPLAFLLRKEGFETTIVTDGPSALAEFERS
. **:::*: .: .: : *::. . *. **
Rv1027c|M.tuberculosis_H37Rv PPDVVILDLGLPDMSGIDVLGGLRGWL-TAPVIVLSARTDSSDKVQALDA
Mb1055c|M.bovis_AF2122/97 PPDVVILDLGLPDMSGIDVLGGLRGWL-TAPVIVLSARTDSSDKVQALDA
MAV_1169|M.avium_104 KPDVVILDLGLPDISGIDVLAGLRGWL-TAPVIVLSARTDSSDKVEALDA
MSMEG_5396|M.smegmatis_MC2_155 RPDVIVLDLGLPDMSGIEVLHGLRGWL-SAPVIVLSARTDSSDKVEALDA
Mvan_4763|M.vanbaalenii_PYR-1 KPDVVVLDLGLPDMTGIEVLAGLRGWL-SAPVIVLSARSDSADKVEALDA
MMAR_0635|M.marinum_M RPDVVILDLGLPDMSGIEVLAGLRGWF-SAPVIVLSARSDSSDKVQALDA
MAB_3250c|M.abscessus_ATCC_199 QPEVVILDLGLPDMDGTEVLAGLRGWT-DVPVIVLSARTDSADKVEALDA
MLBr_02123|M.leprae_Br4923 RPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEA
Mflv_0082|M.gilvum_PYR-GCK GADIVLLDLMLPGMSGTDVCKQLRSRS-SVPVIMVTARDSEIDKVVGLEL
MUL_4560|M.ulcerans_Agy99 GADIVLLDLMLPGMSGTDVCKQLRARS-SVPVIMVTARDSEIDKVVGLEL
TH_4312|M.thermoresistible__bu GADIILLDLMLPGMSGTDVCRRLRAKS-KVPVIMVTARDSEIDKVVGLEL
.: ::**: :* : * .* **. .** :::** . *:* .*:
Rv1027c|M.tuberculosis_H37Rv GADDYVTKPFGMDEFLARLRAAVRRNTAAAELEQP--VIETDSFTVDLAG
Mb1055c|M.bovis_AF2122/97 GADDYVTKPFGMDEFLARLRAAVRRNTAAAELEQP--VIETDSFTVDLAG
MAV_1169|M.avium_104 GADDYVTKPFGMDEFLARLRAAVRRNTAASEMEQP--VVETESFTVDLAA
MSMEG_5396|M.smegmatis_MC2_155 GADDYVTKPFGMDEFLARLRAAARR-AAVPETDQP--VIETTSFTVDLAA
Mvan_4763|M.vanbaalenii_PYR-1 GADDYVTKPFGMDEFLARLRAAVRRGATAAETDEP--VIETSSFTVDLAA
MMAR_0635|M.marinum_M GADDYVTKPFGMDELLARLRAAVRRAATATDTDQP--VIETSSFTVDLAT
MAB_3250c|M.abscessus_ATCC_199 GADDYVTKPFGMDEFLARLRAAVRR--GTPDSAEP--VVHTETFDVDLSS
MLBr_02123|M.leprae_Br4923 GADDYLVKPFVLAELVARVKALLRRRGATATSSSE--TIAVGPLEVDIPG
Mflv_0082|M.gilvum_PYR-GCK GADDYVTKPYSARELIARIRAVLRRGADADDLGVADGVLEAGPVRMDVER
MUL_4560|M.ulcerans_Agy99 GADDYVTKPYSARELIARIRAVLRRGGD-DDSEVSDGVLESGPVRMDVER
TH_4312|M.thermoresistible__bu GADDYVTKPYSARELIARIRAVLRRGSDLDGADVDDSVLEAGPVRMDVDR
*****:.**: *::**::* ** .: .. :*:
Rv1027c|M.tuberculosis_H37Rv KKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWGPAYATETH
Mb1055c|M.bovis_AF2122/97 KKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWGPAYATETH
MAV_1169|M.avium_104 KKVTKNGSEVHLTPTEWGMLEVLVRNRGKLVGREELLKEVWGPAYATETH
MSMEG_5396|M.smegmatis_MC2_155 KKVIKNGAEVHLTPTEWGMLEMLVRNRGKLVGREELLREVWGPAYATETH
Mvan_4763|M.vanbaalenii_PYR-1 KKVTKGGVEVHLTPTEWGMLEMLVRHRGKLVGREELLKEVWGPAYAKETH
MMAR_0635|M.marinum_M KKVIKNGSEVHLTPTEWGMLEMLVRNRGKLVGREELLKEVWGPAYAKETH
MAB_3250c|M.abscessus_ATCC_199 HKVIRDGREVHLTPTEWSMLAVLVRNRGKLVGQKELLHEVWGPAYSSETH
MLBr_02123|M.leprae_Br4923 RRARVNGVDVDLTKREFDLLAVLAEHKTTVLSRAQLLELVWGYDFAADTN
Mflv_0082|M.gilvum_PYR-GCK HVVSVNGAPITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTK
MUL_4560|M.ulcerans_Agy99 HVVSVNGDAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTK
TH_4312|M.thermoresistible__bu HVVTVRGEPITLPLKEFELLEYLLRNSGRVLTRGQLIDRVWGADYVGDTK
: . * : *. *: :* * .: :: : :*: *** : :*:
Rv1027c|M.tuberculosis_H37Rv YLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA-
Mb1055c|M.bovis_AF2122/97 YLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA-
MAV_1169|M.avium_104 YLRVYLAQLRRKLENDPSHPKHLLTESGMGYRFEA-
MSMEG_5396|M.smegmatis_MC2_155 YLRVYLAQLRRKLEDDPSHPVHLLTEAGMGYRFEA-
Mvan_4763|M.vanbaalenii_PYR-1 YLRVYLAQLRRKLEDDPSHPVHLLTEAGMGYRFQQ-
MMAR_0635|M.marinum_M YLRVYLAQLRRKLEDDPAHPRHLLTEAGMGYRFDG-
MAB_3250c|M.abscessus_ATCC_199 YLRVYLAQLRRKLEIDPAHPKHLLTEAGMGYRFQE-
MLBr_02123|M.leprae_Br4923 VVDVFIGYLRRKLEAN-SGPRLLHTVRGVGFVLRMQ
Mflv_0082|M.gilvum_PYR-GCK TLDVHVKRLRSKIESDPANPVHLVTVRGLGYKLEG-
MUL_4560|M.ulcerans_Agy99 TLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG-
TH_4312|M.thermoresistible__bu TLDVHVKRLRSKIEEDPANPVHLVTVRGLGYKLEG-
: *.: ** *:* : : * * * *:*: :