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TRVLVIDDEPQILRALRINLSVRGYEVVTASTGAGALRAAAEHKPDVVILDLGLPDISGIDVLAGLRGWL TAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRNTAASEMEQPVVETESFTVDLAA KKVTKNGSEVHLTPTEWGMLEVLVRNRGKLVGREELLKEVWGPAYATETHYLRVYLAQLRRKLENDPSHP KHLLTESGMGYRFEA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1169 | - | - | 100% (226) | KDP operon transcriptional regulatory protein KdpE |
| M. avium 104 | MAV_4209 | - | 8e-43 | 39.37% (221) | DNA-binding response regulator MtrA |
| M. avium 104 | MAV_4660 | - | 2e-42 | 39.82% (226) | DNA-binding response regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1055c | kdpE | 1e-117 | 91.15% (226) | transcriptional regulatory protein KdpE |
| M. gilvum PYR-GCK | Mflv_4712 | - | 4e-43 | 39.37% (221) | two component transcriptional regulator |
| M. tuberculosis H37Rv | Rv1027c | kdpE | 1e-117 | 91.15% (226) | transcriptional regulatory protein KdpE |
| M. leprae Br4923 | MLBr_00773 | mtrA | 9e-43 | 38.91% (221) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_3250c | - | 1e-101 | 80.89% (225) | transcriptional regulatory protein KdpE |
| M. marinum M | MMAR_0635 | kdpE | 1e-110 | 86.22% (225) | transcriptional regulatory protein KdpE |
| M. smegmatis MC2 155 | MSMEG_5396 | - | 1e-109 | 86.67% (225) | KDP operon transcriptional regulatory protein KdpE |
| M. thermoresistible (build 8) | TH_4129 | - | 8e-44 | 39.37% (221) | PUTATIVE DNA-binding response regulator MtrA |
| M. ulcerans Agy99 | MUL_4560 | regX3 | 3e-42 | 39.82% (226) | two component sensory transduction protein RegX3 |
| M. vanbaalenii PYR-1 | Mvan_4763 | - | 1e-109 | 86.16% (224) | two component transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1055c|M.bovis_AF2122/97 -----------MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALR
Rv1027c|M.tuberculosis_H37Rv -----------MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALR
MAV_1169|M.avium_104 -----------MTRVLVIDDEPQILRALRINLSVRGYEVVTASTGAGALR
MSMEG_5396|M.smegmatis_MC2_155 ------MTAPIKTRVLVIDDEPQILRALRINLSVRGYEVRTAASGAEALH
Mvan_4763|M.vanbaalenii_PYR-1 ------MTS-VKTRVLVIDDEPQILRALRINLSVRGYEVHTAASGAEALR
MMAR_0635|M.marinum_M -----------MTRVLVIDDEPQILRALRINFSVRGYDVVTAATGAAALR
MAB_3250c|M.abscessus_ATCC_199 -----------MTRVLVVDDEPQILRAMRINLSARGYEVVTASSGAGALR
Mflv_4712|M.gilvum_PYR-GCK -------MDSMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVIGDGTQALT
MLBr_00773|M.leprae_Br4923 -------MDIMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALT
TH_4129|M.thermoresistible__bu LSRFGDNMDTMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVIGDGSQALT
MUL_4560|M.ulcerans_Agy99 ----------MTS-VLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALA
:*:::*: .: : : : .*::. . *. **
Mb1055c|M.bovis_AF2122/97 AAAEHPPDVVILDLGLPDMSGIDVLGGLRGWLTAPVIVLSARTDSSDKVQ
Rv1027c|M.tuberculosis_H37Rv AAAEHPPDVVILDLGLPDMSGIDVLGGLRGWLTAPVIVLSARTDSSDKVQ
MAV_1169|M.avium_104 AAAEHKPDVVILDLGLPDISGIDVLAGLRGWLTAPVIVLSARTDSSDKVE
MSMEG_5396|M.smegmatis_MC2_155 SAADHRPDVIVLDLGLPDMSGIEVLHGLRGWLSAPVIVLSARTDSSDKVE
Mvan_4763|M.vanbaalenii_PYR-1 MAADHKPDVVVLDLGLPDMTGIEVLAGLRGWLSAPVIVLSARSDSADKVE
MMAR_0635|M.marinum_M AAAEQRPDVVILDLGLPDMSGIEVLAGLRGWFSAPVIVLSARSDSSDKVQ
MAB_3250c|M.abscessus_ATCC_199 AAAETQPEVVILDLGLPDMDGTEVLAGLRGWTDVPVIVLSARTDSADKVE
Mflv_4712|M.gilvum_PYR-GCK AVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVL
MLBr_00773|M.leprae_Br4923 AVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVL
TH_4129|M.thermoresistible__bu AVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKSDTVDVVL
MUL_4560|M.ulcerans_Agy99 EFDRSGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVV
.::::*** **.: * :* **. .*:::::*: . * *
Mb1055c|M.bovis_AF2122/97 ALDAGADDYVTKPFGMDEFLARLRAAVRRN-TAAAELEQPVIETDSFTVD
Rv1027c|M.tuberculosis_H37Rv ALDAGADDYVTKPFGMDEFLARLRAAVRRN-TAAAELEQPVIETDSFTVD
MAV_1169|M.avium_104 ALDAGADDYVTKPFGMDEFLARLRAAVRRN-TAASEMEQPVVETESFTVD
MSMEG_5396|M.smegmatis_MC2_155 ALDAGADDYVTKPFGMDEFLARLRAAARR--AAVPETDQPVIETTSFTVD
Mvan_4763|M.vanbaalenii_PYR-1 ALDAGADDYVTKPFGMDEFLARLRAAVRRG-ATAAETDEPVIETSSFTVD
MMAR_0635|M.marinum_M ALDAGADDYVTKPFGMDELLARLRAAVRRA-ATATDTDQPVIETSSFTVD
MAB_3250c|M.abscessus_ATCC_199 ALDAGADDYVTKPFGMDEFLARLRAAVRR---GTPDSAEPVVHTETFDVD
Mflv_4712|M.gilvum_PYR-GCK GLESGADDYVMKPFKPKELVARVRARLRRNEDEPAEM----LSIADVDID
MLBr_00773|M.leprae_Br4923 GLESGADDYIMKPFKPKELVARVRARLRRNDDEPAEM----LSIADVDID
TH_4129|M.thermoresistible__bu GLESGADDYVVKPFKPKELVARVRARLRRNEDEPAEM----LSIGDIDID
MUL_4560|M.ulcerans_Agy99 GLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEVSDGVLESGPVRMD
.*: *****: **: *::**:** ** .: : . :*
Mb1055c|M.bovis_AF2122/97 LAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWGPAYAT
Rv1027c|M.tuberculosis_H37Rv LAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWGPAYAT
MAV_1169|M.avium_104 LAAKKVTKNGSEVHLTPTEWGMLEVLVRNRGKLVGREELLKEVWGPAYAT
MSMEG_5396|M.smegmatis_MC2_155 LAAKKVIKNGAEVHLTPTEWGMLEMLVRNRGKLVGREELLREVWGPAYAT
Mvan_4763|M.vanbaalenii_PYR-1 LAAKKVTKGGVEVHLTPTEWGMLEMLVRHRGKLVGREELLKEVWGPAYAK
MMAR_0635|M.marinum_M LATKKVIKNGSEVHLTPTEWGMLEMLVRNRGKLVGREELLKEVWGPAYAK
MAB_3250c|M.abscessus_ATCC_199 LSSHKVIRDGREVHLTPTEWSMLAVLVRNRGKLVGQKELLHEVWGPAYSS
Mflv_4712|M.gilvum_PYR-GCK VPAHKVTRQGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPA
MLBr_00773|M.leprae_Br4923 VPAHKVTRNGEHISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPA
TH_4129|M.thermoresistible__bu VPAHKVTRNGEQIQLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPA
MUL_4560|M.ulcerans_Agy99 VERHVVSVNGDAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVG
: : * * : *. *:.:* * *: ::. : *: .*** :
Mb1055c|M.bovis_AF2122/97 ETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA-
Rv1027c|M.tuberculosis_H37Rv ETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA-
MAV_1169|M.avium_104 ETHYLRVYLAQLRRKLENDPSHPKHLLTESGMGYRFEA-
MSMEG_5396|M.smegmatis_MC2_155 ETHYLRVYLAQLRRKLEDDPSHPVHLLTEAGMGYRFEA-
Mvan_4763|M.vanbaalenii_PYR-1 ETHYLRVYLAQLRRKLEDDPSHPVHLLTEAGMGYRFQQ-
MMAR_0635|M.marinum_M ETHYLRVYLAQLRRKLEDDPAHPRHLLTEAGMGYRFDG-
MAB_3250c|M.abscessus_ATCC_199 ETHYLRVYLAQLRRKLEIDPAHPKHLLTEAGMGYRFQE-
Mflv_4712|M.gilvum_PYR-GCK DTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP
MLBr_00773|M.leprae_Br4923 DTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
TH_4129|M.thermoresistible__bu DTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP
MUL_4560|M.ulcerans_Agy99 DTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG-
:*: : *:: :** *:* ** :* ::* *:**: