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MTRVLVIDDEPQILRALRINFSVRGYDVVTAATGAAALRAAAEQRPDVVILDLGLPDMSGIEVLAGLRGW FSAPVIVLSARSDSSDKVQALDAGADDYVTKPFGMDELLARLRAAVRRAATATDTDQPVIETSSFTVDLA TKKVIKNGSEVHLTPTEWGMLEMLVRNRGKLVGREELLKEVWGPAYAKETHYLRVYLAQLRRKLEDDPAH PRHLLTEAGMGYRFDG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0635 | kdpE | - | 100% (226) | transcriptional regulatory protein KdpE |
| M. marinum M | MMAR_0816 | regX3 | 1e-42 | 39.65% (227) | two-component sensory transduction protein RegX3 |
| M. marinum M | MMAR_4633 | prrA | 9e-42 | 39.82% (221) | two-component response transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1055c | kdpE | 1e-108 | 85.33% (225) | transcriptional regulatory protein KdpE |
| M. gilvum PYR-GCK | Mflv_0082 | - | 1e-43 | 40.35% (228) | two component transcriptional regulator |
| M. tuberculosis H37Rv | Rv1027c | kdpE | 1e-108 | 85.33% (225) | transcriptional regulatory protein KdpE |
| M. leprae Br4923 | MLBr_00773 | mtrA | 4e-42 | 38.57% (223) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_3250c | - | 1e-98 | 78.12% (224) | transcriptional regulatory protein KdpE |
| M. avium 104 | MAV_1169 | - | 1e-111 | 86.22% (225) | KDP operon transcriptional regulatory protein KdpE |
| M. smegmatis MC2 155 | MSMEG_5396 | - | 1e-109 | 87.05% (224) | KDP operon transcriptional regulatory protein KdpE |
| M. thermoresistible (build 8) | TH_4129 | - | 6e-44 | 39.91% (223) | PUTATIVE DNA-binding response regulator MtrA |
| M. ulcerans Agy99 | MUL_4560 | regX3 | 7e-43 | 39.65% (227) | two component sensory transduction protein RegX3 |
| M. vanbaalenii PYR-1 | Mvan_4763 | - | 1e-110 | 88.34% (223) | two component transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1055c|M.bovis_AF2122/97 -----------MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALR
Rv1027c|M.tuberculosis_H37Rv -----------MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALR
MAV_1169|M.avium_104 -----------MTRVLVIDDEPQILRALRINLSVRGYEVVTASTGAGALR
MSMEG_5396|M.smegmatis_MC2_155 ------MTAPIKTRVLVIDDEPQILRALRINLSVRGYEVRTAASGAEALH
Mvan_4763|M.vanbaalenii_PYR-1 ------MTS-VKTRVLVIDDEPQILRALRINLSVRGYEVHTAASGAEALR
MMAR_0635|M.marinum_M -----------MTRVLVIDDEPQILRALRINFSVRGYDVVTAATGAAALR
MAB_3250c|M.abscessus_ATCC_199 -----------MTRVLVVDDEPQILRAMRINLSARGYEVVTASSGAGALR
Mflv_0082|M.gilvum_PYR-GCK ----------MTS-VLIVEDEESLADPLAFLLRKEGFETTVVTDGPSALA
MUL_4560|M.ulcerans_Agy99 ----------MTS-VLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALA
MLBr_00773|M.leprae_Br4923 -------MDIMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALT
TH_4129|M.thermoresistible__bu LSRFGDNMDTMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVIGDGSQALT
:*:::*: .: : : : .*::. . *. **
Mb1055c|M.bovis_AF2122/97 AAAEHPPDVVILDLGLPDMSGIDVLGGLRGWLTAPVIVLSARTDSSDKVQ
Rv1027c|M.tuberculosis_H37Rv AAAEHPPDVVILDLGLPDMSGIDVLGGLRGWLTAPVIVLSARTDSSDKVQ
MAV_1169|M.avium_104 AAAEHKPDVVILDLGLPDISGIDVLAGLRGWLTAPVIVLSARTDSSDKVE
MSMEG_5396|M.smegmatis_MC2_155 SAADHRPDVIVLDLGLPDMSGIEVLHGLRGWLSAPVIVLSARTDSSDKVE
Mvan_4763|M.vanbaalenii_PYR-1 MAADHKPDVVVLDLGLPDMTGIEVLAGLRGWLSAPVIVLSARSDSADKVE
MMAR_0635|M.marinum_M AAAEQRPDVVILDLGLPDMSGIEVLAGLRGWFSAPVIVLSARSDSSDKVQ
MAB_3250c|M.abscessus_ATCC_199 AAAETQPEVVILDLGLPDMDGTEVLAGLRGWTDVPVIVLSARTDSADKVE
Mflv_0082|M.gilvum_PYR-GCK EFERAGADIVLLDLMLPGMSGTDVCKQLRSRSSVPVIMVTARDSEIDKVV
MUL_4560|M.ulcerans_Agy99 EFDRSGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVV
MLBr_00773|M.leprae_Br4923 AVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVL
TH_4129|M.thermoresistible__bu AVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKSDTVDVVL
.::::*** **.: * :* **. .*:::::*: . * *
Mb1055c|M.bovis_AF2122/97 ALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAAEL--EQPVIETDSFTV
Rv1027c|M.tuberculosis_H37Rv ALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAAEL--EQPVIETDSFTV
MAV_1169|M.avium_104 ALDAGADDYVTKPFGMDEFLARLRAAVRRNTAASEM--EQPVVETESFTV
MSMEG_5396|M.smegmatis_MC2_155 ALDAGADDYVTKPFGMDEFLARLRAAARR-AAVPET--DQPVIETTSFTV
Mvan_4763|M.vanbaalenii_PYR-1 ALDAGADDYVTKPFGMDEFLARLRAAVRRGATAAET--DEPVIETSSFTV
MMAR_0635|M.marinum_M ALDAGADDYVTKPFGMDELLARLRAAVRRAATATDT--DQPVIETSSFTV
MAB_3250c|M.abscessus_ATCC_199 ALDAGADDYVTKPFGMDEFLARLRAAVRR--GTPDS--AEPVVHTETFDV
Mflv_0082|M.gilvum_PYR-GCK GLELGADDYVTKPYSARELIARIRAVLRRGADADDLGVADGVLEAGPVRM
MUL_4560|M.ulcerans_Agy99 GLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSEVSDGVLESGPVRM
MLBr_00773|M.leprae_Br4923 GLESGADDYIMKPFKPKELVARVRARLRRNDD-----EPAEMLSIADVDI
TH_4129|M.thermoresistible__bu GLESGADDYVVKPFKPKELVARVRARLRRNED-----EPAEMLSIGDIDI
.*: *****: **: *::**:** ** :: . :
Mb1055c|M.bovis_AF2122/97 DLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWGPAYA
Rv1027c|M.tuberculosis_H37Rv DLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWGPAYA
MAV_1169|M.avium_104 DLAAKKVTKNGSEVHLTPTEWGMLEVLVRNRGKLVGREELLKEVWGPAYA
MSMEG_5396|M.smegmatis_MC2_155 DLAAKKVIKNGAEVHLTPTEWGMLEMLVRNRGKLVGREELLREVWGPAYA
Mvan_4763|M.vanbaalenii_PYR-1 DLAAKKVTKGGVEVHLTPTEWGMLEMLVRHRGKLVGREELLKEVWGPAYA
MMAR_0635|M.marinum_M DLATKKVIKNGSEVHLTPTEWGMLEMLVRNRGKLVGREELLKEVWGPAYA
MAB_3250c|M.abscessus_ATCC_199 DLSSHKVIRDGREVHLTPTEWSMLAVLVRNRGKLVGQKELLHEVWGPAYS
Mflv_0082|M.gilvum_PYR-GCK DVERHVVSVNGAPITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYV
MUL_4560|M.ulcerans_Agy99 DVERHVVSVNGDAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYV
MLBr_00773|M.leprae_Br4923 DVPAHKVTRNGEHISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHP
TH_4129|M.thermoresistible__bu DVPAHKVTRNGEQIQLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHP
*: : * .* : *. *:.:* * *: ::. : *: .*** :
Mb1055c|M.bovis_AF2122/97 TETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA-
Rv1027c|M.tuberculosis_H37Rv TETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA-
MAV_1169|M.avium_104 TETHYLRVYLAQLRRKLENDPSHPKHLLTESGMGYRFEA-
MSMEG_5396|M.smegmatis_MC2_155 TETHYLRVYLAQLRRKLEDDPSHPVHLLTEAGMGYRFEA-
Mvan_4763|M.vanbaalenii_PYR-1 KETHYLRVYLAQLRRKLEDDPSHPVHLLTEAGMGYRFQQ-
MMAR_0635|M.marinum_M KETHYLRVYLAQLRRKLEDDPAHPRHLLTEAGMGYRFDG-
MAB_3250c|M.abscessus_ATCC_199 SETHYLRVYLAQLRRKLEIDPAHPKHLLTEAGMGYRFQE-
Mflv_0082|M.gilvum_PYR-GCK GDTKTLDVHVKRLRSKIESDPANPVHLVTVRGLGYKLEG-
MUL_4560|M.ulcerans_Agy99 GDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG-
MLBr_00773|M.leprae_Br4923 ADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
TH_4129|M.thermoresistible__bu ADTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP
:*: : *:: :** *:* ** :* ::* *:**: