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MTAPIKTRVLVIDDEPQILRALRINLSVRGYEVRTAASGAEALHSAADHRPDVIVLDLGLPDMSGIEVLH GLRGWLSAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAARRAAVPETDQPVIETTSFT VDLAAKKVIKNGAEVHLTPTEWGMLEMLVRNRGKLVGREELLREVWGPAYATETHYLRVYLAQLRRKLED DPSHPVHLLTEAGMGYRFEA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5396 | - | - | 100% (230) | KDP operon transcriptional regulatory protein KdpE |
| M. smegmatis MC2 155 | MSMEG_5488 | - | 7e-42 | 39.29% (224) | DNA-binding response regulator |
| M. smegmatis MC2 155 | MSMEG_1874 | mtrA | 2e-41 | 37.78% (225) | DNA-binding response regulator MtrA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1055c | kdpE | 1e-107 | 85.78% (225) | transcriptional regulatory protein KdpE |
| M. gilvum PYR-GCK | Mflv_4712 | - | 1e-41 | 37.78% (225) | two component transcriptional regulator |
| M. tuberculosis H37Rv | Rv1027c | kdpE | 1e-107 | 85.78% (225) | transcriptional regulatory protein KdpE |
| M. leprae Br4923 | MLBr_00773 | mtrA | 1e-41 | 37.33% (225) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_3250c | - | 4e-97 | 76.68% (223) | transcriptional regulatory protein KdpE |
| M. marinum M | MMAR_0635 | kdpE | 1e-109 | 87.05% (224) | transcriptional regulatory protein KdpE |
| M. avium 104 | MAV_1169 | - | 1e-109 | 86.67% (225) | KDP operon transcriptional regulatory protein KdpE |
| M. thermoresistible (build 8) | TH_4129 | - | 4e-42 | 37.78% (225) | PUTATIVE DNA-binding response regulator MtrA |
| M. ulcerans Agy99 | MUL_2582 | mtrA | 4e-41 | 36.89% (225) | two component sensory transduction transcriptional |
| M. vanbaalenii PYR-1 | Mvan_4763 | - | 1e-113 | 89.38% (226) | two component transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1055c|M.bovis_AF2122/97 -----------MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALR
Rv1027c|M.tuberculosis_H37Rv -----------MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALR
MAV_1169|M.avium_104 -----------MTRVLVIDDEPQILRALRINLSVRGYEVVTASTGAGALR
MSMEG_5396|M.smegmatis_MC2_155 ------MTAPIKTRVLVIDDEPQILRALRINLSVRGYEVRTAASGAEALH
Mvan_4763|M.vanbaalenii_PYR-1 ------MTS-VKTRVLVIDDEPQILRALRINLSVRGYEVHTAASGAEALR
MMAR_0635|M.marinum_M -----------MTRVLVIDDEPQILRALRINFSVRGYDVVTAATGAAALR
MAB_3250c|M.abscessus_ATCC_199 -----------MTRVLVVDDEPQILRAMRINLSARGYEVVTASSGAGALR
MLBr_00773|M.leprae_Br4923 -------MDIMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALT
MUL_2582|M.ulcerans_Agy99 -------MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALT
Mflv_4712|M.gilvum_PYR-GCK -------MDSMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVIGDGTQALT
TH_4129|M.thermoresistible__bu LSRFGDNMDTMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVIGDGSQALT
:**:**:..: . : * : .*::. . . *: **
Mb1055c|M.bovis_AF2122/97 AAAEHPPDVVILDLGLPDMSGIDVLGGLRGWLTAPVIVLSARTDSSDKVQ
Rv1027c|M.tuberculosis_H37Rv AAAEHPPDVVILDLGLPDMSGIDVLGGLRGWLTAPVIVLSARTDSSDKVQ
MAV_1169|M.avium_104 AAAEHKPDVVILDLGLPDISGIDVLAGLRGWLTAPVIVLSARTDSSDKVE
MSMEG_5396|M.smegmatis_MC2_155 SAADHRPDVIVLDLGLPDMSGIEVLHGLRGWLSAPVIVLSARTDSSDKVE
Mvan_4763|M.vanbaalenii_PYR-1 MAADHKPDVVVLDLGLPDMTGIEVLAGLRGWLSAPVIVLSARSDSADKVE
MMAR_0635|M.marinum_M AAAEQRPDVVILDLGLPDMSGIEVLAGLRGWFSAPVIVLSARSDSSDKVQ
MAB_3250c|M.abscessus_ATCC_199 AAAETQPEVVILDLGLPDMDGTEVLAGLRGWTDVPVIVLSARTDSADKVE
MLBr_00773|M.leprae_Br4923 AVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVL
MUL_2582|M.ulcerans_Agy99 AVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVL
Mflv_4712|M.gilvum_PYR-GCK AVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVL
TH_4129|M.thermoresistible__bu AVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKSDTVDVVL
. : *::::*** **.: * :* **. .*:::*:*::*: * *
Mb1055c|M.bovis_AF2122/97 ALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAAELEQPVIETDSFTVDL
Rv1027c|M.tuberculosis_H37Rv ALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAAELEQPVIETDSFTVDL
MAV_1169|M.avium_104 ALDAGADDYVTKPFGMDEFLARLRAAVRRNTAASEMEQPVVETESFTVDL
MSMEG_5396|M.smegmatis_MC2_155 ALDAGADDYVTKPFGMDEFLARLRAAARR-AAVPETDQPVIETTSFTVDL
Mvan_4763|M.vanbaalenii_PYR-1 ALDAGADDYVTKPFGMDEFLARLRAAVRRGATAAETDEPVIETSSFTVDL
MMAR_0635|M.marinum_M ALDAGADDYVTKPFGMDELLARLRAAVRRAATATDTDQPVIETSSFTVDL
MAB_3250c|M.abscessus_ATCC_199 ALDAGADDYVTKPFGMDEFLARLRAAVRR--GTPDSAEPVVHTETFDVDL
MLBr_00773|M.leprae_Br4923 GLESGADDYIMKPFKPKELVARVRARLRR---NDDEPAEMLSIADVDIDV
MUL_2582|M.ulcerans_Agy99 GLESGADDYIMKPFKPKELVARVRARLRR---NDDEPAEMLSIADVDIDV
Mflv_4712|M.gilvum_PYR-GCK GLESGADDYVMKPFKPKELVARVRARLRR---NEDEPAEMLSIADVDIDV
TH_4129|M.thermoresistible__bu GLESGADDYVVKPFKPKELVARVRARLRR---NEDEPAEMLSIGDIDIDV
.*::*****: *** .*::**:** ** : :: . :*:
Mb1055c|M.bovis_AF2122/97 AGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWGPAYATE
Rv1027c|M.tuberculosis_H37Rv AGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWGPAYATE
MAV_1169|M.avium_104 AAKKVTKNGSEVHLTPTEWGMLEVLVRNRGKLVGREELLKEVWGPAYATE
MSMEG_5396|M.smegmatis_MC2_155 AAKKVIKNGAEVHLTPTEWGMLEMLVRNRGKLVGREELLREVWGPAYATE
Mvan_4763|M.vanbaalenii_PYR-1 AAKKVTKGGVEVHLTPTEWGMLEMLVRHRGKLVGREELLKEVWGPAYAKE
MMAR_0635|M.marinum_M ATKKVIKNGSEVHLTPTEWGMLEMLVRNRGKLVGREELLKEVWGPAYAKE
MAB_3250c|M.abscessus_ATCC_199 SSHKVIRDGREVHLTPTEWSMLAVLVRNRGKLVGQKELLHEVWGPAYSSE
MLBr_00773|M.leprae_Br4923 PAHKVTRNGEHISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPAD
MUL_2582|M.ulcerans_Agy99 PAHKATRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPAD
Mflv_4712|M.gilvum_PYR-GCK PAHKVTRQGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPAD
TH_4129|M.thermoresistible__bu PAHKVTRNGEQIQLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPAD
. :*. : * .: *** *:.:* *.*: ::. : **.:*** :. :
Mb1055c|M.bovis_AF2122/97 THYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA-
Rv1027c|M.tuberculosis_H37Rv THYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA-
MAV_1169|M.avium_104 THYLRVYLAQLRRKLENDPSHPKHLLTESGMGYRFEA-
MSMEG_5396|M.smegmatis_MC2_155 THYLRVYLAQLRRKLEDDPSHPVHLLTEAGMGYRFEA-
Mvan_4763|M.vanbaalenii_PYR-1 THYLRVYLAQLRRKLEDDPSHPVHLLTEAGMGYRFQQ-
MMAR_0635|M.marinum_M THYLRVYLAQLRRKLEDDPAHPRHLLTEAGMGYRFDG-
MAB_3250c|M.abscessus_ATCC_199 THYLRVYLAQLRRKLEIDPAHPKHLLTEAGMGYRFQE-
MLBr_00773|M.leprae_Br4923 TRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
MUL_2582|M.ulcerans_Agy99 TRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Mflv_4712|M.gilvum_PYR-GCK TRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP
TH_4129|M.thermoresistible__bu TRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP
*: :.*:: :** *:* ** :* :** *:**: