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TSVLIVEDEESLADPLAFLLRKEGFETTVVTDGPSALAEFERAGADIVLLDLMLPGMSGTDVCKQLRSRS SVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGADADDLGVADGVLEAGPVRMDV ERHVVSVNGAPITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIESDPA NPVHLVTVRGLGYKLEG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0082 | - | - | 100% (228) | two component transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4712 | - | 5e-56 | 49.55% (224) | two component transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0893 | - | 4e-47 | 44.05% (227) | two component transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0501 | regX3 | 1e-117 | 93.86% (228) | two component sensory transduction protein RegX3 |
| M. tuberculosis H37Rv | Rv0491 | regX3 | 1e-117 | 93.86% (228) | two component sensory transduction protein RegX3 |
| M. leprae Br4923 | MLBr_02439 | - | 7e-99 | 91.41% (198) | putative two-component system response regulator |
| M. abscessus ATCC 19977 | MAB_4047c | - | 1e-116 | 91.23% (228) | sensory transduction protein RegX3 |
| M. marinum M | MMAR_0816 | regX3 | 1e-117 | 93.86% (228) | two-component sensory transduction protein RegX3 |
| M. avium 104 | MAV_4660 | - | 1e-116 | 93.42% (228) | DNA-binding response regulator |
| M. smegmatis MC2 155 | MSMEG_0937 | regX3 | 1e-118 | 95.56% (225) | DNA-binding response regulator RegX3 |
| M. thermoresistible (build 8) | TH_4312 | - | 1e-115 | 90.35% (228) | PUTATIVE two component transcriptional regulator, winged helix |
| M. ulcerans Agy99 | MUL_4560 | regX3 | 1e-117 | 93.86% (228) | two component sensory transduction protein RegX3 |
| M. vanbaalenii PYR-1 | Mvan_0831 | - | 1e-121 | 96.05% (228) | two component transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0082|M.gilvum_PYR-GCK MTSVLIVEDEESLADPLAFLLRKEGFETTVVTDGPSALAEFERAGADIVL
Mvan_0831|M.vanbaalenii_PYR-1 MTSVLIVEDEESLADPLAFLLRKEGFEATVVADGPSALAEFERAGADIVL
MMAR_0816|M.marinum_M MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRSGADIVL
MUL_4560|M.ulcerans_Agy99 MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRSGADIVL
MLBr_02439|M.leprae_Br4923 -----------------------------MVTDGPAALAEFDRSGADIVL
Mb0501|M.bovis_AF2122/97 MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVL
Rv0491|M.tuberculosis_H37Rv MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVL
MAV_4660|M.avium_104 MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGSAALAEFDRAGADIVL
MSMEG_0937|M.smegmatis_MC2_155 ---MLIVEDEESLADPLAFLLRKEGFEATVVGDGPSALAEFERSGADIVL
MAB_4047c|M.abscessus_ATCC_199 MTSVLIVEDEDSLADPLAFLLRKEGFEATIVNDGPSALAEFERAGADIVL
TH_4312|M.thermoresistible__bu MTSVLIVEDEESLADPLAFLLRKEGFETTIVTDGPSALAEFERSGADIIL
:* **.:*****:*:****:*
Mflv_0082|M.gilvum_PYR-GCK LDLMLPGMSGTDVCKQLRSRSSVPVIMVTARDSEIDKVVGLELGADDYVT
Mvan_0831|M.vanbaalenii_PYR-1 LDLMLPGMSGTDVCKQLRSRSSVPVIMVTARDSEIDKVVGLELGADDYVT
MMAR_0816|M.marinum_M LDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVT
MUL_4560|M.ulcerans_Agy99 LDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVT
MLBr_02439|M.leprae_Br4923 LDLMLPGMSGTDVYKQLRVRSSVPVIMVTARDSEIDKVVGLELGADDYVT
Mb0501|M.bovis_AF2122/97 LDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVT
Rv0491|M.tuberculosis_H37Rv LDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVT
MAV_4660|M.avium_104 LDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVT
MSMEG_0937|M.smegmatis_MC2_155 LDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVT
MAB_4047c|M.abscessus_ATCC_199 LDLMLPGMSGTDVCKQLRAKSSVPVIMVTARDSEIDKVVGLELGADDYVT
TH_4312|M.thermoresistible__bu LDLMLPGMSGTDVCRRLRAKSKVPVIMVTARDSEIDKVVGLELGADDYVT
************* ::** :*.****************************
Mflv_0082|M.gilvum_PYR-GCK KPYSARELIARIRAVLRRGADADDLGVADGVLEAGPVRMDVERHVVSVNG
Mvan_0831|M.vanbaalenii_PYR-1 KPYSARELIARIRAVLRRGSDADDAGIGDGVLEAGPVRMDVERHVVSVNG
MMAR_0816|M.marinum_M KPYSARELIARIRAVLRRGGD-DDSEVSDGVLESGPVRMDVERHVVSVNG
MUL_4560|M.ulcerans_Agy99 KPYSARELIARIRAVLRRGGD-DDSEVSDGVLESGPVRMDVERHVVSVNG
MLBr_02439|M.leprae_Br4923 KPYSARELIARIRAVLRRGGD-DDSEISDGVLESGPLRMDVERHVVSVNG
Mb0501|M.bovis_AF2122/97 KPYSARELIARIRAVLRRGGD-DDSEMSDGVLESGPVRMDVERHVVSVNG
Rv0491|M.tuberculosis_H37Rv KPYSARELIARIRAVLRRGGD-DDSEMSDGVLESGPVRMDVERHVVSVNG
MAV_4660|M.avium_104 KPYSARELIARIRAVLRRGGD-DDSEISDGVLESGPVRMDVERHVVSVNG
MSMEG_0937|M.smegmatis_MC2_155 KPYSARELIARIRAVLRRGADNDDAGADDGVLEAGPVRMDVERHVVSVNG
MAB_4047c|M.abscessus_ATCC_199 KPYSARELIARIRAVLRRGSDSEETASGDGVLEAGPVRMDVDRHTVSVNG
TH_4312|M.thermoresistible__bu KPYSARELIARIRAVLRRGSDLDGADVDDSVLEAGPVRMDVDRHVVTVRG
*******************.* : *.***:**:****:**.*:*.*
Mflv_0082|M.gilvum_PYR-GCK APITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
Mvan_0831|M.vanbaalenii_PYR-1 QSITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
MMAR_0816|M.marinum_M DAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
MUL_4560|M.ulcerans_Agy99 DAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
MLBr_02439|M.leprae_Br4923 YAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGVDYVGDTKTLDVHVK
Mb0501|M.bovis_AF2122/97 DTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
Rv0491|M.tuberculosis_H37Rv DTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
MAV_4660|M.avium_104 DTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
MSMEG_0937|M.smegmatis_MC2_155 EPITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
MAB_4047c|M.abscessus_ATCC_199 EAITLPLKEFDLLEYLIRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
TH_4312|M.thermoresistible__bu EPITLPLKEFELLEYLLRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
.********:*****:******************.**************
Mflv_0082|M.gilvum_PYR-GCK RLRSKIESDPANPVHLVTVRGLGYKLEG
Mvan_0831|M.vanbaalenii_PYR-1 RLRSKIEADPANPVHLVTVRGLGYKLEG
MMAR_0816|M.marinum_M RLRSKIEADPANPVHLVTVRGLGYKLEG
MUL_4560|M.ulcerans_Agy99 RLRSKIEADPANPVHLVTVRGLGYKLEG
MLBr_02439|M.leprae_Br4923 RLRSKIEADPANPVHLVTVRGLGYKLES
Mb0501|M.bovis_AF2122/97 RLRSKIEADPANPVHLVTVRGLGYKLEG
Rv0491|M.tuberculosis_H37Rv RLRSKIEADPANPVHLVTVRGLGYKLEG
MAV_4660|M.avium_104 RLRSKIEADPANPVHLVTVRGLGYKLEG
MSMEG_0937|M.smegmatis_MC2_155 RLRSKIEEDPANPVHLVTVRGLGYKLEG
MAB_4047c|M.abscessus_ATCC_199 RLRSKIEADPANPVHLVTVRGLGYKLEG
TH_4312|M.thermoresistible__bu RLRSKIEEDPANPVHLVTVRGLGYKLEG
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