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M. tuberculosis H37Rv Rv0980c (PE_PGRS18)

annotation: PE-PGRS FAMILY PROTEIN
coordinates: 1095078 - 1096451
length: 457

SFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAHDEVSTAIAALFGSHGQHYQAISAQVAAY
QERFVLALSQASSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNG
GNGGSGAPGQAGGAGGAAGLIGNGGAGGAGGQGLPFEAGANGGAGGAGGWLFGNGGAGGVGGAGGAGTTF
GVAGGDGGTGGVGGHGGLIGVGGHGGDGGTGGTGGAVSLARAGTAGGAGGGPAGGIGGAGGVGGAGGAAG
AVTTITHASFNDPHGVAVNPGGNIYVTNQGSNTVSVIDPVTNTVTGSITDGNGPSGVAVSPVTGLVFVTN
FDSNTVSVIDPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSVIDPATNTVTGSPIPVGLDPTG
VAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0980cPE_PGRS18-100% (457)PE-PGRS FAMILY PROTEIN
M. tuberculosis H37RvRv0978cPE_PGRS17e-14171.04% (404) PE-PGRS family protein
M. tuberculosis H37RvRv2615cPE_PGRS45e-13166.08% (398) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1006cPE_PGRS180.099.56% (457) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-8e-4352.91% (172) triple helix repeat-containing collagen
M. leprae Br4923MLBr_01183-6e-1039.78% (93) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_0321c-3e-2641.06% (207) hypothetical protein MAB_0321c
M. marinum MMMAR_3758-4e-9357.80% (327) PE-PGRS family protein
M. avium 104MAV_4827-5e-2242.94% (163) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-7e-4136.90% (336) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_4332-6e-2534.15% (287) PUTATIVE -
M. ulcerans Agy99MUL_0572-5e-9148.91% (413) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-2e-4341.52% (289) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Rv0980c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb1006c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3758|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb1006c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3758|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb1006c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3758|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb1006c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3758|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        ------------------------------------MSFVNVAPQLVSTA
Mb1006c|M.bovis_AF2122/97           ------------------------------------MSFVNVAPQLVSTA
MLBr_01183|M.leprae_Br4923          -----------------------------------MPLFLNAEPQALTAA
MUL_0572|M.ulcerans_Agy99           ------------------------------------MSYVVAIPDMLASA
MMAR_3758|M.marinum_M               ------------------------------------MSYVLVTPEMVATA
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MAB_0321c|M.abscessus_ATCC_199      ------------------------------------------MANIISNG
TH_4332|M.thermoresistible__bu      ------------------------------------MPFITSGAAFVGGA
MAV_4827|M.avium_104                ----------------------------------------MNIVLGVSMA
                                                                                     .

Rv0980c|M.tuberculosis_H37Rv        AADAARIGSAINTAN-TAAAATTQVLAAAHDEVSTAIAALFGSHGQHYQA
Mb1006c|M.bovis_AF2122/97           AADAARIGSAINTAN-TAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQA
MLBr_01183|M.leprae_Br4923          ANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQA
MUL_0572|M.ulcerans_Agy99           AADVAGIGSSVGAANTAAVGATTGVMAAADDEVSVAIAALFSGHGQAYQA
MMAR_3758|M.marinum_M               AADAAAIGSTVSAANAAAAIPTTAIATAAADDVSAAIAALFNAHAEQYQA
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MAB_0321c|M.abscessus_ATCC_199      PDGDAGATGAQGSQGATGAAGAMANCN-WIDDDCATRGGTGGTGGNGGPG
TH_4332|M.thermoresistible__bu      AMLLAGPGGVSALEAAGSAPRTVEYEYSLVACDSTLPLMCEAGDSVGGLG
MAV_4827|M.avium_104                PSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTRE
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        ISAQVAAYQERFVLALSQASSTYAVAEAASATPLQN----VLDAINAPVQ
Mb1006c|M.bovis_AF2122/97           ISAQVAAYQERFVLALSQASSTYAVAEAASATPLQN----VLDAINAPVQ
MLBr_01183|M.leprae_Br4923          HASQGATNHQDLIQSLLTSSSAYAGTETANHDSL----------------
MUL_0572|M.ulcerans_Agy99           ISAQAAAFHDQFLRALTGAGGAYAAAEAANASPLQAAEQEVLAVINAPTN
MMAR_3758|M.marinum_M               LSVRVAELHESFTRALTAGSTAYATAEAANAGPLQP----LLDLINAPTQ
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
MAB_0321c|M.abscessus_ATCC_199      GAGGPGGHGGVIDFEVETFMDGVTLQAKGGRG------------------
TH_4332|M.thermoresistible__bu      GASHDRSAFSASALGMASFGPDWNPGGAFLGLIGPG---------GLLIG
MAV_4827|M.avium_104                GAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALA
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        SLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNG---------------
Mb1006c|M.bovis_AF2122/97           SLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNG---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           ALLGRPLIGNGTDGLAGTGAAGGAGGLLWGNGGNG---------------
MMAR_3758|M.marinum_M               ALLARPLIGDGSNGAPGTGQAGGNGGLLIGNGGAG---------------
Mflv_5091|M.gilvum_PYR-GCK          VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1       VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155      GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      DGLNGTDAYIDENGVFHEATRGGNGGLLWGNGGKG---------------
MAV_4827|M.avium_104                QNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP---------------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        -GSGAPGQAGGAGGAAG---LIGNGGAG----------------------
Mb1006c|M.bovis_AF2122/97           -GSGAPGQAGGAGGAAG---LIGNGGAG----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           -GSGAAGQAGGAGGAAG---LIGTGGAGGMGGA-----GGGAGGMGGSGG
MMAR_3758|M.marinum_M               -GSGAPGQRGGAGGAGGL--LLGNGGAGGAGGVGALGQASGTGGNGGAGG
Mflv_5091|M.gilvum_PYR-GCK          VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1       VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155      VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      -GNGLDAGLYTVPDPDN---------------------------------
MAV_4827|M.avium_104                DVYKQQIRAESYGDAAG---------------------------------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        ------GAGGQGLPFEAGANGGAGGAGG-------------WLFGNGGAG
Mb1006c|M.bovis_AF2122/97           ------GAGGQGLPFEAGANGGAGGAGG-------------WLFGNGGAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           WLLGNGGAGGAGGVGCAGVSGGVGGTGGNA-----------MLFGNGGAG
MMAR_3758|M.marinum_M               LLFGKGGAGGAGGVGGLGQAGGTGGNGGAGG----------LLFGNGGAG
Mflv_5091|M.gilvum_PYR-GCK          AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1       AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155      AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
MAB_0321c|M.abscessus_ATCC_199      -----------------------------------------GNGGHGGAG
TH_4332|M.thermoresistible__bu      -------PGSTIQMYFEASDGADGGRGG-------------FLFGNGGDG
MAV_4827|M.avium_104                ----------QLSAMVAGLEKLESLPGG------------LLLVGSGVDV
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        GVGG-AGGAGTT------------------------------FGVAGGDG
Mb1006c|M.bovis_AF2122/97           GVGG-AGGAGTT------------------------------FGVAGGDG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           GMGG-AGADGAVGAAGTAGTSTSAGGVGGAGWDATAAGVLAATGGDGGDS
MMAR_3758|M.marinum_M               GVGG-AGGVGGVDSAGGTGGTGGTGGANG-LFGAAGSGGSGGAGGDGAPG
Mflv_5091|M.gilvum_PYR-GCK          GVGG-VGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ
Mvan_1264|M.vanbaalenii_PYR-1       QAGG-IGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ
MSMEG_0868|M.smegmatis_MC2_155      TGTG-IGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEI
MAB_0321c|M.abscessus_ATCC_199      GTGG-TGGK-----------------------------------------
TH_4332|M.thermoresistible__bu      GNGGNVGGKNGADP-----------------------------VTATVAA
MAV_4827|M.avium_104                APLKQVLQTTTFLD-----------------------------VSVAEEP
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        GTGGVGGHGGLIGVGGHG--------------------------------
Mb1006c|M.bovis_AF2122/97           GTGGVGGHGGLIGVGGHG--------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           GGGGAGGNGGAGGAGGHGSALFGADGANGNGGAGGAGGNPGAPGNGGTGG
MMAR_3758|M.marinum_M               DTAGAGGTGGTGSAGGAGGTG-GAGGANQFFGHAGDGGHGGTGGTGGTGG
Mflv_5091|M.gilvum_PYR-GCK          --GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG----------
Mvan_1264|M.vanbaalenii_PYR-1       --GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG----------
MSMEG_0868|M.smegmatis_MC2_155      YSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGT
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      DKSVAGGNGGNGGRGGLLFG------------------------------
MAV_4827|M.avium_104                ETALARGAALAAANAPLFASSTAALAYAQD--------------------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb1006c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           VGPDAATSGGMGGTGGDPGAVGGRGNS--------------GAAGGAGAV
MMAR_3758|M.marinum_M               AGGSGVGSGLAGGAGGDGGAGGAAGRG--------------GAAGAGGPL
Mflv_5091|M.gilvum_PYR-GCK          ---LQGGKGGDGGAGGKGGDADSMGS------------------AGATGG
Mvan_1264|M.vanbaalenii_PYR-1       ---LQGGQGGDGGTGGTGGDATSMGE------------------AGATGG
MSMEG_0868|M.smegmatis_MC2_155      AKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGA
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        -----------------------------------GDGGT----------
Mb1006c|M.bovis_AF2122/97           -----------------------------------GDGGT----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           AGASGAAGTIIAGNGGNGGAGGAGYAADGPAGPAIGNGGD----------
MMAR_3758|M.marinum_M               VTPGHAGNTGTG-----------------------GTGGT----------
Mflv_5091|M.gilvum_PYR-GCK          KGGNGGNGGRGGLFG---------------KGGNAGNGAD----------
Mvan_1264|M.vanbaalenii_PYR-1       KGGNGGNGGRGSLFG---------------RGGNAGNGGN----------
MSMEG_0868|M.smegmatis_MC2_155      VGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNG
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        ------------GGTGGAVSLARAGTAGGAGG------------------
Mb1006c|M.bovis_AF2122/97           ------------GGTGGAVSLARAGTAGGAGG------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           ------------GGHGGAGGFYGNGGAGGAGGN-----------------
MMAR_3758|M.marinum_M               ------------GGTGGNGDLHTNGGNGGTGGSGGA--------------
Mflv_5091|M.gilvum_PYR-GCK          ------------GGTGGAGGAGGTGG-TGGAGGTGG--------------
Mvan_1264|M.vanbaalenii_PYR-1       ------------GGTGGNGGNGGTGG-TGGNGGTGG--------------
MSMEG_0868|M.smegmatis_MC2_155      PAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTG
MAB_0321c|M.abscessus_ATCC_199      ------------GGDGDDCEFGRTGGNGGTGGR-----------------
TH_4332|M.thermoresistible__bu      -----------LGGNGGNGGWSTTSYLDARGGN-----------------
MAV_4827|M.avium_104                ------------PGTGAVDQYSLPDYLYVPVDPEPG--------------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        ----------GPAGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNP
Mb1006c|M.bovis_AF2122/97           ----------GPAGGIGGTGGVGGAGGAAGAVTTITHASFNDPHGVAVNP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           ---------SAPGGGTGGNGGTGGDSGAMGSSGGRGGDGGVGTNGGAGGG
MMAR_3758|M.marinum_M               -------GIAGVGGGNGGTGGDGGKGGTGANGAPLGASGGTGGDGGKGGG
Mflv_5091|M.gilvum_PYR-GCK          ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
Mvan_1264|M.vanbaalenii_PYR-1       ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
MSMEG_0868|M.smegmatis_MC2_155      QTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGR
MAB_0321c|M.abscessus_ATCC_199      -------------GGDGNFAGTGGNGGAILVKCQHDLSLGTHPMDVSAGT
TH_4332|M.thermoresistible__bu      -------------GGNGGLGGVLRPGGLLSLLLPSGAASEPGGLFTGGNG
MAV_4827|M.avium_104                ---------DDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVG
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        GGNIYVTNQGSN------TVSVIDPVTNTVTG--------------SITD
Mb1006c|M.bovis_AF2122/97           GGNIYVTNQGSN------TVSVIDPVTNTVTG--------------SITD
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           GGNATSYGTANA------TGGAGGDGGTGSTGNGGSG-GDGGNGGTGHGG
MMAR_3758|M.marinum_M               GGNATDGGHGGNG----GTGGTAGDGGNGQSGDLN------ANGGGGGRG
Mflv_5091|M.gilvum_PYR-GCK          GGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      GGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNG
MAB_0321c|M.abscessus_ATCC_199      GGNGGIGGGGGGG---------GSVGANGATTG-----------------
TH_4332|M.thermoresistible__bu      GNGGLAIANHWVG----ITDGVPGPDDDAVSSSAYG--------------
MAV_4827|M.avium_104                SGLAVVGISAVLALEIALAIGIRTTGTVALQPTPN---------------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        GNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPNTNTVTGSIP---------
Mb1006c|M.bovis_AF2122/97           GNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPNTNTVTGSIP---------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           GGGPGGTAINYGAGDAFGGAAGKGGTGVVGGNGGSGGAAYN---------
MMAR_3758|M.marinum_M               GTGGAGGIGGTTTGGGDAGAGGGGGAGGTGGSGGEGGAGGF---------
Mflv_5091|M.gilvum_PYR-GCK          GAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------
Mvan_1264|M.vanbaalenii_PYR-1       GAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---------
MSMEG_0868|M.smegmatis_MC2_155      GAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVI
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        ------VGTG---AYGVAVNPGGNIYVTN------------------QFS
Mb1006c|M.bovis_AF2122/97           ------VGTG---AYGVAVNPGGNIYVTN------------------QFS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           ------YGTGNATGAGGSSGSGGAASVPN------------------SAS
MMAR_3758|M.marinum_M               ------GGDGGAGGTGGKAGAGGDGGNAT------------------DGG
Mflv_5091|M.gilvum_PYR-GCK          --------TGGTGGQGG-LGGGGGTG-----------------------G
Mvan_1264|M.vanbaalenii_PYR-1       --------TGGTGGQGG-LGGVGGTG-----------------------G
MSMEG_0868|M.smegmatis_MC2_155      GSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDG
MAB_0321c|M.abscessus_ATCC_199      -------------------------------------------------V
TH_4332|M.thermoresistible__bu      -------------------------------------------------G
MAV_4827|M.avium_104                -------------------------------------------------Q
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        NTVSVIDPAT--NTVTGSPIPVG--------LDPTGVAVNPVTGVVYVTN
Mb1006c|M.bovis_AF2122/97           NTVSVIDPAT--NTVTGSPIPVG--------LDPTGVAVNPVTGVVYVTN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           TATATSGSGG--AGGDGTDGGNG--------GSGGFAFTFGTGNIIAGVG
MMAR_3758|M.marinum_M               NAGAGGDGGTGGAGGTGGGIVTG--------INGGAGGAGGDGGDSGNGG
Mflv_5091|M.gilvum_PYR-GCK          QGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
MSMEG_0868|M.smegmatis_MC2_155      HGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGG
MAB_0321c|M.abscessus_ATCC_199      FSSSSDCSGPGPQPNPGSPGDPG---------------------------
TH_4332|M.thermoresistible__bu      HGGHGAGPGSGGNGGSAVANSLG-------NAIAGNGGDAGRFVLIGPGG
MAV_4827|M.avium_104                HLIVPTEQAPAPPPVQASAPQPK-------ISVPEPVAAPKPLSPPVAAP
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        SLDDTVSVITGEPARSVCSAAI----------------------------
Mb1006c|M.bovis_AF2122/97           SLDDTVSVITGEPARSVCSAAI----------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           GGGGTGSTGVGGIGGSGGGADINNGAFTVVPQGGAGGHG-----GDGAT-
MMAR_3758|M.marinum_M               NATGGGNGGNGGTAGTGGAGGLGGGGFRVGHGGGGGNGG-----NGGVGG
Mflv_5091|M.gilvum_PYR-GCK          SGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGK
Mvan_1264|M.vanbaalenii_PYR-1       VGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGT
MSMEG_0868|M.smegmatis_MC2_155      DGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGST
MAB_0321c|M.abscessus_ATCC_199      -TSVAVSGAQGNPGQAQFLIVP----------------------------
TH_4332|M.thermoresistible__bu      NGGNGGTGLXXXPRPRRRRNHRRTRRRPNGRRPRPPPGR-----------
MAV_4827|M.avium_104                LPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSP
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb1006c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           ------DGGAGGAG-----GFTEIDSSASVIAATGGAGGDGGSGGTGRGG
MMAR_3758|M.marinum_M               TATAGGDAGSGGTGGVGGDGSVGGDASDAVAGGDGGTGGRGGSGGAGGIA
Mflv_5091|M.gilvum_PYR-GCK          AGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGAT
Mvan_1264|M.vanbaalenii_PYR-1       AGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSA
MSMEG_0868|M.smegmatis_MC2_155      LGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDG
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                PQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTP
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb1006c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           TGGGGTGGGGTGGGGGVG--INNGSGEAIGGAPGAGGTGAVGGDGGQGGA
MMAR_3758|M.marinum_M               TGGGSAGHGGVGGGGGNGGHGTDGTAGVAGHGGGAGGAGGDAGDGGKGGD
Mflv_5091|M.gilvum_PYR-GCK          GAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
Mvan_1264|M.vanbaalenii_PYR-1       GSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
MSMEG_0868|M.smegmatis_MC2_155      GAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGW
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                PKPDGPGNYGGGHVPTPGAGGSGGSGGGHVPTPGAGGSGGSGGGHVPTPG
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb1006c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           AYSYGTGDATG--------SAGAAGTAGTTGVGGTGGAGGAAYT------
MMAR_3758|M.marinum_M               ALDGGTAGAGG--------AGGKAGNGGGAGSGGKGTFDGGAGG------
Mflv_5091|M.gilvum_PYR-GCK          AGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG------
Mvan_1264|M.vanbaalenii_PYR-1       AGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG------
MSMEG_0868|M.smegmatis_MC2_155      VQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWK
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                TGGPGGTGGSG---------GGHVPTPGAGTPGGSGGGHLPFPG------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb1006c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           -----LNGASTATATGGIGGNGGDGGTANGSNGGNGGAGGYASTTGTGTA
MMAR_3758|M.marinum_M               -----AGGDGGKAGNGGAGGIDSNGQVADGGDGGDGGNGGDGGNGGDGSP
Mflv_5091|M.gilvum_PYR-GCK          -----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1       -----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG
MSMEG_0868|M.smegmatis_MC2_155      SGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSG
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                ---AGSTPGGSGGGHLPTPGAGTPGGGLGGFGGGHAPAPGGGLGGGGGHA
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb1006c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           SVGNGGRGGDGTATVATGGTGGVGGNAHAPAGSPVPGVGGKGGNPGPGGK
MMAR_3758|M.marinum_M               -VGAGGTGGIGTAGGAGGGGGAVSGRPGQNGSEGQPG-------------
Mflv_5091|M.gilvum_PYR-GCK          --GAGGSGGSGGSGGSGGSGGAAGDSDD----------------------
Mvan_1264|M.vanbaalenii_PYR-1       --GAGGSGGSGGSGGAGGSGGAAGDSD-----------------------
MSMEG_0868|M.smegmatis_MC2_155      NGGNGGNGGNGGADGTPGTAGTTGANNP----------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                PAPGGGLGGFGGGHSGGGLGGLGGGHK-----------------------
                                                                                      

Rv0980c|M.tuberculosis_H37Rv        -----------
Mb1006c|M.bovis_AF2122/97           -----------
MLBr_01183|M.leprae_Br4923          -----------
MUL_0572|M.ulcerans_Agy99           PGPNGADGIVV
MMAR_3758|M.marinum_M               -----------
Mflv_5091|M.gilvum_PYR-GCK          -----------
Mvan_1264|M.vanbaalenii_PYR-1       -----------
MSMEG_0868|M.smegmatis_MC2_155      -----------
MAB_0321c|M.abscessus_ATCC_199      -----------
TH_4332|M.thermoresistible__bu      -----------
MAV_4827|M.avium_104                -----------