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LIGNGGAGGSGAPGAIGGAGGPAGLIGVGGAGGAGGDSAVAGVIGGAGGAGGAALLFGAGGAGGAGGSGG SGAAGGAGGAGGAGGLFASGGSGGFGGFASTGTGGAGGTGGAGGLFASGGVGGTGGGAGSGGTGGVGGTG GAGGLFASGGAGGAGGSGGTGGAGGTGGAGGLFGAGGAGGLGGQGNHTGGHGGAGGSAGLLALGDGGAGG AGGAATTGTGGAGGAGGKAGLLFGSGGAGGSGGAAGTFGDTGNSGGAGGAGGKAGLLFGSGGAGGSGGAG GFANGSTGGAGGAGGGAGLIGNGGNGGSGGTSVATGGAGNGGAGGAGGGAGLIGNGGNGGSGGMGDAPGG TGVGGIGGLLLGLDGANAPASTNPLHTAQQQALAAVNAPIQAVTGRPLIGNGANGAPGSGAPGGHGGWLF GGGGTGGSGVSGGAGGDGGAGGILFGAGGAGGAGGAVTGTGATGGSGGAGGGALLFGAGGAGGAGGSSGI GGFAAGGAGGPGGAGGLFNGGGAGGAGGSGVSGGAGGEGGAGGAGGLFAGGGAGGAGGSGNNVGGAGGAG GVGGLFGAGGAGGSGGGGSVAGDSGAGGNAGLLAPGLAGGAGGGGGQGFDTGGAGGPGGDAGLLVGSGGV GGAGGFGLTTGGPGAAGGDAGLLFGSGGAGGAGGSGRTDLGGAGGAGGKAGLIGNGGNGGAGGAGGNGGG DGGPGGAAFGLGNGGNGGNGGTGTSAGSPGAGGAGGSLIGAEGLPGLLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0833 | PE_PGRS13 | - | 100% (749) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1759c | wag22 | 0.0 | 60.40% (803) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv0278c | PE_PGRS3 | 0.0 | 60.41% (778) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0856 | PE_PGRS13 | 0.0 | 95.62% (777) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-161 | 48.05% (768) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01556 | infB | 4e-09 | 41.30% (92) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 4e-52 | 35.50% (476) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4399 | - | 0.0 | 58.85% (814) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 3e-26 | 46.06% (165) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-125 | 38.01% (976) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 3e-40 | 40.06% (312) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3062 | - | 0.0 | 56.87% (786) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-160 | 47.31% (782) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0833|M.tuberculosis_H37Rv --------------------------------------------------
Mb0856|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M --------------------------------------------------
MUL_3062|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Rv0833|M.tuberculosis_H37Rv --------------------------------------------------
Mb0856|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M -------------MSYVIAVPDLVAGAASELAGVGSTLSTATTAAAAQTT
MUL_3062|M.ulcerans_Agy99 -------------MAFVLAVPDMVAEAAADLAGVGSVIDAANTAAAGSTT
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 -------------MAGKARVHELAKELGVTSKEVLARLNEQG--------
Rv0833|M.tuberculosis_H37Rv --------------------------------------------------
Mb0856|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M G-------------------------------------VLAAAGDEVSAA
MUL_3062|M.ulcerans_Agy99 G-------------------------------------IVAAAEDEVSAA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Rv0833|M.tuberculosis_H37Rv -----------------------------------------MIGNGGAGG
Mb0856|M.bovis_AF2122/97 -----------------------------------------MIGNGGAGG
MMAR_4399|M.marinum_M IAAVFSAHG-------------QSYQTLSAQAETFHAQFVQALSAGASAY
MUL_3062|M.ulcerans_Agy99 IAALFSGHG-------------QAYQQISTRVAEFHAQFERVFAAGVQAY
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------MSIIDFILNL
MAV_4827|M.avium_104 ---------------------------------------MNIVLGVSMAP
MLBr_01556|M.leprae_Br4923 -------------------------------------EFVKSASSTVEAP
Rv0833|M.tuberculosis_H37Rv SG---------------------APGAIGG--------------------
Mb0856|M.bovis_AF2122/97 SG---------------------APGAIGG--------------------
MMAR_4399|M.marinum_M TQ---------------------AEAASAS----------PLAGLLAAIN
MUL_3062|M.ulcerans_Agy99 SG---------------------AEAANASFL------QDPLQTALNATN
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 FR---------------------DPVEAAS--------------------
MAV_4827|M.avium_104 SS------------------------------------------------
MLBr_01556|M.leprae_Br4923 VAR--------------------RLRESFG--------------------
Rv0833|M.tuberculosis_H37Rv ------------AGGPAGLIG-----VGGAGGAG------GDSAVAGVIG
Mb0856|M.bovis_AF2122/97 ------------AGGPAGLIG-----VGGAGGAG------GDSAVAGVIG
MMAR_4399|M.marinum_M APVQSLTGRPLIGNGANGTPG-----TGADGAPGGWLLGDGGAGGSGAPG
MUL_3062|M.ulcerans_Agy99 KPVQDLTGRPLVGNGANGVPG-----TGANGAAGGWLLGNGGAGGSGAAG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 -----YVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVN
MAV_4827|M.avium_104 ------IQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILG
MLBr_01556|M.leprae_Br4923 -------GIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGA
Rv0833|M.tuberculosis_H37Rv GAGGAGGAAL---LFGAGGAGGAGGSG--GSGAAGG--AGGAGGAGG-LF
Mb0856|M.bovis_AF2122/97 GAGGAGGAAL---LFGAGGAGGAGGSG--GSGAAGG--AGGAGGAGG-LF
MMAR_4399|M.marinum_M LNGGAGGAAG---LLGSGGAGGAGGSS---TSTNGG--AGGAGGAGGWLS
MUL_3062|M.ulcerans_Agy99 QAGGDGGAAG---LIGAGGAGGAGGNSPLRNTANGG--NGGTGGAGGLLF
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGG---
MAB_4284c|M.abscessus_ATCC_199 TGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDN----DFLSHNDTDF
MAV_4827|M.avium_104 TREGAADAGLQLSSIGVTWTDQLEAAALRDALAARR--IDNVMLVSAFLA
MLBr_01556|M.leprae_Br4923 TTAAPVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQ
Rv0833|M.tuberculosis_H37Rv ASGGSGGFGGFASTGTGGAGGTGGAGGLFASGGVGGTGG----------G
Mb0856|M.bovis_AF2122/97 ASGGSGGFGGFASTGTGGAGGTGGAGGLFASGGVGGTGG----------G
MMAR_4399|M.marinum_M GNAGVGGAGGASTVANGGAGGAGGAGGLLGGGGLGGAGG----------A
MUL_3062|M.ulcerans_Agy99 GPGGVGGAGGASFLT-GGTGGDGGAGGLFGAGGLGGVGG----------S
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAG-AAGAAGAAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAG-AAGAAGKAG--------------
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAG-AAGNGGDGGNGGFGYVLIAGPNV
TH_3810|M.thermoresistible__bu ------GTGIISLLSLAGNGGNGGNGYRTTDN------------------
MAB_4284c|M.abscessus_ATCC_199 ASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGN-----------
MAV_4827|M.avium_104 AAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP----------
MLBr_01556|M.leprae_Br4923 GTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSS---------AQ
.
Rv0833|M.tuberculosis_H37Rv AGSG-GTGGVGGTGGAGG-LFA--SGGAGGAGGSGGTGGAGGTGGAGG--
Mb0856|M.bovis_AF2122/97 AGSG-GTGGVGGTGGAGG-LFA--SGGAGGAGGSGGTGGAGGTGGAGG--
MMAR_4399|M.marinum_M STSATASGGAGGQGGAAG-LLSGFVGADGGHGGAGGHGAAGGDGGAGGDG
MUL_3062|M.ulcerans_Agy99 GN----VGGNGGAGGAGG-LLAGLVGAGGGDGGSGGLGAAGGDGGNGGRA
Mflv_5091|M.gilvum_PYR-GCK AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG-----
Mvan_1264|M.vanbaalenii_PYR-1 AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG-----
MSMEG_0868|M.smegmatis_MC2_155 TVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDG
TH_3810|M.thermoresistible__bu ---NALDGGHGGNGGNVGFFSLFNLGGAGGWGGSG---------------
MAB_4284c|M.abscessus_ATCC_199 RDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSN---
MAV_4827|M.avium_104 -DVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLK
MLBr_01556|M.leprae_Br4923 SVARPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPG
. * .
Rv0833|M.tuberculosis_H37Rv --LFGAGGAGGLGGQGNHTGGHGGAGGSAGLLALGDGGAGGAGGAATTG-
Mb0856|M.bovis_AF2122/97 --LFGAGGAGGLGGQGNHTGGHGGAGGSAGLLALGDGGAGGAGGAATTG-
MMAR_4399|M.marinum_M GPLAGAGGSGGTGGSGNAGGGAGGAGGNAGLL-FGDGGVGGTGGTSGQG-
MUL_3062|M.ulcerans_Agy99 GLFGGAGGAGGMGATGGHSGGDGGAGGDAGLL-FGTGGAGGAGGHAFDG-
Mflv_5091|M.gilvum_PYR-GCK --AAGTVGTAGATG-GTGTGANGGAGGVG-----GVGGTGAAGAAGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 --VAGAAGTAGATG-GTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGT
MSMEG_0868|M.smegmatis_MC2_155 HAIGGNGGNGGNGS-TTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG
TH_3810|M.thermoresistible__bu ------------------VDGVDVVGGNP------DGGTPGAHGESHTP-
MAB_4284c|M.abscessus_ATCC_199 --VGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFN
MAV_4827|M.avium_104 QVLQTTTFLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQDPG-
MLBr_01556|M.leprae_Br4923 APVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRG-
.
Rv0833|M.tuberculosis_H37Rv ------TGGAGGAG-------------------GKAGLLFGSGGAGGSGG
Mb0856|M.bovis_AF2122/97 ------TGGAGGAG-------------------GKAGLLFGSGGAGGSGG
MMAR_4399|M.marinum_M ------VGGIGGDG-------------------GSAGLLFSNGGAGGAGG
MUL_3062|M.ulcerans_Agy99 ------DGGAGGAG-------------------GNAGLMFSSGGSGGVGG
Mflv_5091|M.gilvum_PYR-GCK LGETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGG
Mvan_1264|M.vanbaalenii_PYR-1 AGETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGG
MSMEG_0868|M.smegmatis_MC2_155 HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGE
TH_3810|M.thermoresistible__bu ------------------------------------GVYTDRQGEDGEDG
MAB_4284c|M.abscessus_ATCC_199 ------TDRSTNIG--------------------SGNTTNTEIGSHNQAN
MAV_4827|M.avium_104 ------TGAVDQYS-------------------LPDYLYVPVDPEPGDDE
MLBr_01556|M.leprae_Br4923 -------GAAGAFG-------------------RPGGAPRRGRKSKRQKR
Rv0833|M.tuberculosis_H37Rv AAGTFGDTGNSGGAGGAGGKAGLLFGSGGAGG----SGGAGG--------
Mb0856|M.bovis_AF2122/97 AAGTFGDTGNSGGAGGAGGKAGLLFGSGGAGG----SGGAGG--------
MMAR_4399|M.marinum_M AGTAL--ISGNGGAGGNGGNGGWLFSNGGVGG----AGGAGAP-----AM
MUL_3062|M.ulcerans_Agy99 AG------SIDGGAGGAGGDAGWLGG-GGAGG----AGGFGT--------
Mflv_5091|M.gilvum_PYR-GCK AG----------STGAVGG-------VGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1 VG----------ATGGAGG-------VGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG
TH_3810|M.thermoresistible__bu TG-----------TG-----------------------------------
MAB_4284c|M.abscessus_ATCC_199 IG----------TSTSAGG-------------------------------
MAV_4827|M.avium_104 LAYS----------------------------------------------
MLBr_01556|M.leprae_Br4923 QEYDSMQAPVVGGVRLPHGNGETIRLARGASLS-----------------
Rv0833|M.tuberculosis_H37Rv ---FANGSTGGAGGAGGGAG-LIGNGGN-----------GGSGGTSVATG
Mb0856|M.bovis_AF2122/97 ---FANGSTGGAGGAGGGAG-LIGNGGN-----------GGSGGTSVATG
MMAR_4399|M.marinum_M PSLGISAGSGGVGGAGGTGGLLLGNGGA-----------GGAGGTSGNGG
MUL_3062|M.ulcerans_Agy99 ----ISD--GGAGGRGGGGGQLLGNGGA-----------GGAGGQGGNDG
Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG
Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG
MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----SAAVGGNAGLAGNAG------------------------LAGNAG
MAV_4827|M.avium_104 ----AVGEEDAESPTVVIEKLFLPEDSE-----------------PRRRP
MLBr_01556|M.leprae_Br4923 ---DFAEKIDANPAALVQALFNLGEMVT--------------ATQSVGDE
Rv0833|M.tuberculosis_H37Rv GAGNGGAGGAGGGAGLIG---------------NGGNGGSGGM-------
Mb0856|M.bovis_AF2122/97 GAGNGGAGGAGGGAGLIG---------------NGGNGGSGGM-------
MMAR_4399|M.marinum_M GTG--GAGGAAGSGVLIG---------------NGGNGGIGGA-------
MUL_3062|M.ulcerans_Agy99 GAG--GLG---GNGVLIG---------------NGGNGGVGGV-------
Mflv_5091|M.gilvum_PYR-GCK GKG--GNGGNGGRGGLFG---------------KGGNAGNGAD-------
Mvan_1264|M.vanbaalenii_PYR-1 GKG--GNGGNGGRGSLFG---------------RGGNAGNGGN-------
MSMEG_0868|M.smegmatis_MC2_155 AVG--GNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYD
TH_3810|M.thermoresistible__bu ---------------------------------IGGRGGNGGS-------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGNAG---------------LAGNAGLAGN-------
MAV_4827|M.avium_104 VLLVGSGLAVVGISAVLA---------------LEIALAIGIR-------
MLBr_01556|M.leprae_Br4923 TLELLGSEMNYNVQVVSP---------------EDEDRELLEP-------
Rv0833|M.tuberculosis_H37Rv ---------------GDAPGGTGVGGIGGLLLGLDGANA-----------
Mb0856|M.bovis_AF2122/97 ---------------GDAPGGTGVGGIGGLLLGLDGANA-----------
MMAR_4399|M.marinum_M ---------------GPTPGGNGIGGTSGLLLGLDGFNA-----------
MUL_3062|M.ulcerans_Agy99 ---------------GETPGGDGGGGISGLLLGADGFNA-----------
Mflv_5091|M.gilvum_PYR-GCK ---------------GGTGGAGGAGGTGG-TGGAGGTGG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------GGTGGNGGNGGTGG-TGGNGGTGG-----------
MSMEG_0868|M.smegmatis_MC2_155 PNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQH
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------AGLAGNAGLAGNAGLAGNAGLAGNAG---------
MAV_4827|M.avium_104 -----------------TTGTVALQPTPNQHLIVPTEQA-----------
MLBr_01556|M.leprae_Br4923 ----------FDLTYGEDQGDEDELQVRPPVVTVMGHVDHG---------
Rv0833|M.tuberculosis_H37Rv ------PASTNPLHTAQQQALAAVNAPIQAVTGRPLIGNGANGAPGSGAP
Mb0856|M.bovis_AF2122/97 ------PASTNPLHTAQQQALAAVNAPIQAVTGRPLIGNGANGAPGSGAP
MMAR_4399|M.marinum_M ------PTSTSPIHTLQQQALNAINAPIQAATGRPLIGNGTPGDAGSGTD
MUL_3062|M.ulcerans_Agy99 ------PAGSSPVHALQQQALAAINAPVQELTGRPLIGNGLPGSAGSGAA
Mflv_5091|M.gilvum_PYR-GCK ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 STGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGD
TH_3810|M.thermoresistible__bu ------SSGTHPMAEDG--------EHVKALDGRPGLDGGNGSHGGNGGH
MAB_4284c|M.abscessus_ATCC_199 ------LAGNAGLAGNAGLAGNAGLAGNAGLAG----NAGLAGNAGLAGN
MAV_4827|M.avium_104 ------PAPPPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAPPPAAP
MLBr_01556|M.leprae_Br4923 -------KTRLLDTIRKANVREAEAGGITQHIGAYQVGVDLDGSERLITF
.
Rv0833|M.tuberculosis_H37Rv GGHGG--WLFGGGGTG----GSGVS--GGAGGDGGAGGI--------LFG
Mb0856|M.bovis_AF2122/97 GGHGG--WLFGGGGTG----GSGVS--GGAGGDGGAGGI--------LFG
MMAR_4399|M.marinum_M GTPGG--WLLGDGGAG----GSGGT--GLDGGDGGAAG---------LMG
MUL_3062|M.ulcerans_Agy99 GAPGG--WLLGDGGAG----GSAAATPGAAGGAGGAAG---------LVG
Mflv_5091|M.gilvum_PYR-GCK GGKGGTGGTGGAGGTG----GDGGT--GGTGGTGGTG---------GTGG
Mvan_1264|M.vanbaalenii_PYR-1 GGKGGTGGTGGDGGTG----GTGGT--GGTGGTGGTG---------GTGG
MSMEG_0868|M.smegmatis_MC2_155 GGRGGDGALGGNGGTGGVGLGNGGK--GGNGGNGGNGGTYVDPSHTGAGG
TH_3810|M.thermoresistible__bu GGRGG---FLGIGGSG---------------------------------G
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAG---NAAVAGNAAVAGNAAVAGN---------AA
MAV_4827|M.avium_104 PLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVS--------PPQ
MLBr_01556|M.leprae_Br4923 IDTPGHEAFTAMRARG--AKATDIAILVVAADDGVMPQT--------VEA
. .
Rv0833|M.tuberculosis_H37Rv AGGAGGAG-----GAVTGTGATGGSGGAGGG-ALLFGAGGAGGAGGSSGI
Mb0856|M.bovis_AF2122/97 AGGAGGAG-----GAVTGTGATGGSGGAGGG-ALLFGAGGAGGAGGSSGI
MMAR_4399|M.marinum_M TGGTGGAGGW--GGTDEITGGTGGAGGTGGGGGWLSGSGGIGGGGGAGGY
MUL_3062|M.ulcerans_Agy99 AGGAGGAG----ANTGISNPGFGGAGGAGG--------AGAGAGGGVG--
Mflv_5091|M.gilvum_PYR-GCK TGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG----
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG----
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALI
TH_3810|M.thermoresistible__bu WGGHGGNG-----------GDTDADGGNGG--------------------
MAB_4284c|M.abscessus_ATCC_199 VGGVLNTG---------VSGAIGGSSHVGG--AINESLGGSGSVGGSTAV
MAV_4827|M.avium_104 LLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTPPK
MLBr_01556|M.leprae_Br4923 INHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFID
. *
Rv0833|M.tuberculosis_H37Rv GG------FAAGGAGGPGGAGG-LFNGGGAG-------------------
Mb0856|M.bovis_AF2122/97 GG------FAAGGAGGPGGAGG-LFNGGGAG-------------------
MMAR_4399|M.marinum_M GGAIIPGNGGAGGSAGAGGAGG-LFGGGGTG-------------------
MUL_3062|M.ulcerans_Agy99 ---------------EAGGAGG-LLGAGGTG-------------------
Mflv_5091|M.gilvum_PYR-GCK -------------TGGTGGQGG-LGGGGGTG-------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------TGGTGGQGG-LGGVGGTG-------------------
MSMEG_0868|M.smegmatis_MC2_155 RATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASG
TH_3810|M.thermoresistible__bu ----------------DGGNGG----------------------------
MAB_4284c|M.abscessus_ATCC_199 GG------------GAHTGVGGGVSTGVGVG-------------------
MAV_4827|M.avium_104 PD-------------GPGNYGGGHVPTPGAG-------------------
MLBr_01556|M.leprae_Br4923 ISAKVGTNIEALLEAVLLTADAALDLRANSG-------------------
..
Rv0833|M.tuberculosis_H37Rv ----GAGGSG--------------VSGGAGGEGGAGGAGGLFAGG-----
Mb0856|M.bovis_AF2122/97 ----GAGGSG--------------VSGGAGGEGGAGGAGGLFAGGGIGGA
MMAR_4399|M.marinum_M ----GAGGTGGPAGLGVFVGVPTFGDGGGGGAGGAGGAGGLLSGLVG---
MUL_3062|M.ulcerans_Agy99 ----GGGGVA-----------PSLVDGGTGGAGGAGGAGGLFGGIFG---
Mflv_5091|M.gilvum_PYR-GCK ----GQGGTG--------------GTGGQGGTGGTGGTGGTG--------
Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTG--------------GTGGQGGTGGTGGTGGTG--------
MSMEG_0868|M.smegmatis_MC2_155 TATDGHGGSG--------------INGGHGGNGGQGTIEANGPSAVA---
TH_3810|M.thermoresistible__bu -------------------------SAGRGGTGGLRGVFGIN--------
MAB_4284c|M.abscessus_ATCC_199 ----SHVGGG--------------ISESLGGSGSVGGSTAVGGGAHT---
MAV_4827|M.avium_104 ----GSGGSG----------------GGHVPTPGAGGSGGSG--------
MLBr_01556|M.leprae_Br4923 -----MEAQG--------VAIEAHLDRGRGPVATVLVQRGTLRIGDS---
. .
Rv0833|M.tuberculosis_H37Rv -----------------------GAGGAGGSG----NNVGGAGGAGGVGG
Mb0856|M.bovis_AF2122/97 GGFGGFRGGEGGAGGAGGLFAGGGAGGAGGSG----NNVGGAGGAGGVGG
MMAR_4399|M.marinum_M --------------------AGGGDGGAGGQGGIGFGGSGGSGGGGGVGG
MUL_3062|M.ulcerans_Agy99 --------------------AGGGDGGAGGFT----GGIDGAGGVGGAGG
Mflv_5091|M.gilvum_PYR-GCK -----------------------GTGGAGGDGG--LGGLGGFGGSGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------GTGGAGGDGG--LGGLGGFGGVGGTGG
MSMEG_0868|M.smegmatis_MC2_155 --------------------SGIGAGGNGGDGI--DGGLGGNGGDGVVNT
TH_3810|M.thermoresistible__bu -------------------------GGNGRAG------LGGRGXXX----
MAB_4284c|M.abscessus_ATCC_199 -----------------------GVGGGVSTG----VGVGSHVGGGISES
MAV_4827|M.avium_104 -------------------------GGHVPTP-----GTGGPGGTGGSGG
MLBr_01556|M.leprae_Br4923 -----------------------VVAGDAYGRVRRMVDEHGVDIEAALPS
.* .
Rv0833|M.tuberculosis_H37Rv ----LFGAGGAGGSGGG----------GSVAGDSGAGGN--AGLLAPGLA
Mb0856|M.bovis_AF2122/97 ----LFGAGGAGGSGGG----------GSVAGDGGAGGN--AGLLAPGLA
MMAR_4399|M.marinum_M NAGLLGGPGGAGGSGGAAGPALFGIGVDGTAGVGGAGGN--AGLLFG--S
MUL_3062|M.ulcerans_Agy99 NTGLLGGPGGSGGSGGD-GIAKLGFNVDG--GAGGAGVN--GGFLFG--S
Mflv_5091|M.gilvum_PYR-GCK QGG-LGGPGGSTGGAGG----AGG--QAGTAGKGGLFG----GSGSAGKA
Mvan_1264|M.vanbaalenii_PYR-1 QGG-QGGPGGSTGGAGG----AGG--QAGVAGKGGLFG----GSGSAGTA
MSMEG_0868|M.smegmatis_MC2_155 TAN-AANPGSATGTATG----GDGGKATGTASQGGNGGPSWVQSGYGSTL
TH_3810|M.thermoresistible__bu -------XGGGVGAAVR---------------------------------
MAB_4284c|M.abscessus_ATCC_199 LGG-SGSVGGSTAVGGG---------------------------AHTGVG
MAV_4827|M.avium_104 GHVPTPGAGTPGGSGGG---------------------------------
MLBr_01556|M.leprae_Br4923 SPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRI
. .
Rv0833|M.tuberculosis_H37Rv GGAGGGGGQG-----FDTGGAGGPG--------GDAGLLVGSGGVGGAGG
Mb0856|M.bovis_AF2122/97 GGAGGGGGQG-----FDTGGAGGPG--------GDAGLLVGSGGVGGAGG
MMAR_4399|M.marinum_M GGAGGDGGFG-----PGAGGTGGRG--------GNAGLLFSSAGAGGFGG
MUL_3062|M.ulcerans_Agy99 GGTGGFGGVGGVGTSTGIGGAGGRG--------GNAGLLFSDAGVGGFGG
Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1 GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
TH_3810|M.thermoresistible__bu ---------------------SGNG-------------VFSGGGGTPSAG
MAB_4284c|M.abscessus_ATCC_199 GGVNTGVGVGSHVGGGISESLGGSG---------------SVGGSTAVGG
MAV_4827|M.avium_104 -----------------HLPFPGAG-----------------STPGGSGG
MLBr_01556|M.leprae_Br4923 SLEDLDSALKETSQLNLILKGDNAG--------TVEALEEALMGIQVDDE
*
Rv0833|M.tuberculosis_H37Rv FGLTTGGPGAAGGDAGL------LFGSGGAGGAGGSGRTDLGGAGGAGGK
Mb0856|M.bovis_AF2122/97 FGLTTGGPGAAGGDAGL------LFGSGGAGGAGGSGRTDLGGAGGAGGK
MMAR_4399|M.marinum_M YGTTGGGTGGAGGDAG-------WLGCGGAGGAGGITIGGTGGTGGAGGT
MUL_3062|M.ulcerans_Agy99 FG-------GTGGNAG-------WLGSGGSGGAGGGSNG-DGGAGGTGGS
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
TH_3810|M.thermoresistible__bu FGVPTTIQFPAG------------SCTSRAVSREGIMPSSRAASARAG--
MAB_4284c|M.abscessus_ATCC_199 GAHTSAINDALG-------------GSGSVGGSTAVGGGAHTSAINESMN
MAV_4827|M.avium_104 GHLPTPGAGTPG---------------GGLGGFGGGHAPAPGGGLGGGGG
MLBr_01556|M.leprae_Br4923 VALRVIDRGVGGITETN-----VNLASASDAIIIGFNVRAEGKATELASR
* . .
Rv0833|M.tuberculosis_H37Rv AG--LIGNGG---------NGGAGG-----AGGNGGGDGGPGG-------
Mb0856|M.bovis_AF2122/97 AG--LIGNGG---------NGGAGG-----AGG----AGGPGG-------
MMAR_4399|M.marinum_M GGQ-LLGAGG---------AGGAGGQTDPLG-GSTGGSGGVGG-------
MUL_3062|M.ulcerans_Agy99 GGQ-IVGDGG---------AGGAGGQGDLLAAGGSGGDGGQGG-------
Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SSINASHSSS----------------------------------------
MAV_4827|M.avium_104 HAP-----------------------------------------------
MLBr_01556|M.leprae_Br4923 EGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRSSKVG
Rv0833|M.tuberculosis_H37Rv ----AAFGLGNGGNGGNGGTGTS--------AGSPGAGGAGGSLIGAEGL
Mb0856|M.bovis_AF2122/97 ----AAFGLGNGGNGGNGGTGTS--------AGSPGAGGAGGSLIGAEGL
MMAR_4399|M.marinum_M ----NAVLIGTGGNGGNGGAGTA--------KGTPGTGGTGG-LIGVDGL
MUL_3062|M.ulcerans_Agy99 ----DAVLIGTGGNGGNGASGVL--------AGIGGDGGSRGLLLGEDGV
Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN
TH_3810|M.thermoresistible__bu ----AACASSTSRSRRSFCCSRA---------------------------
MAB_4284c|M.abscessus_ATCC_199 -----MNESFGSSMGSHGAAGTG--------FEAQGHAQGHASETAHTTL
MAV_4827|M.avium_104 --------APGGGLGGFGGGHSG--------GGLGGLGGGHK--------
MLBr_01556|M.leprae_Br4923 IIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGF
Rv0833|M.tuberculosis_H37Rv PGLLP-----------------------
Mb0856|M.bovis_AF2122/97 PGLLP-----------------------
MMAR_4399|M.marinum_M SGAS------------------------
MUL_3062|M.ulcerans_Agy99 NGEAAPPMTHIVLLGGDFPAAAS-----
Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD-
Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD--
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGGADGTPGTAGTTGANNP-
TH_3810|M.thermoresistible__bu ----------------------------
MAB_4284c|M.abscessus_ATCC_199 PGAEHH----------------------
MAV_4827|M.avium_104 ----------------------------
MLBr_01556|M.leprae_Br4923 ECGMTLGYSDIKEGDVIESYELVEKQRA