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TQTGSARFEGDSWDLASSVGLTATMVAAARAVAGRAPGALVNDQFAEPLVRAVGVDFFVRMASGELDPDE LAEDEANGLRRFADAMAIRTHYFDNFFLDATRAGIRQAVILASGLDSRAYRLRWPAGTIVFEVDQPQVID FKTTTLAGLGAAPTTDRRTVAVDLRDDWPTALQKAGFDNAQRTAWIAEGLLGYLSAEAQDRLLDQITAQS VPGSQFATEVLRDINRLNEEELRGRMRRLAERFRRHGLDLDMSGLVYFGDRTDARTYLADHGWRTASAST TDLLAEHGLPPIDGDDAPFGEVIYVSAELKQKHQDTR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0731c | - | - | 100% (318) | hypothetical protein Rv0731c |
| M. tuberculosis H37Rv | Rv0726c | - | e-106 | 60.88% (317) | hypothetical protein Rv0726c |
| M. tuberculosis H37Rv | Rv3399 | - | 6e-89 | 55.08% (305) | hypothetical protein Rv3399 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0752c | - | 0.0 | 100.00% (318) | hypothetical protein Mb0752c |
| M. gilvum PYR-GCK | Mflv_5023 | - | 8e-97 | 57.24% (304) | putative methyltransferase |
| M. leprae Br4923 | MLBr_02640 | - | 4e-58 | 43.41% (311) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3787 | - | 9e-81 | 52.44% (307) | hypothetical protein MAB_3787 |
| M. marinum M | MMAR_1069 | - | 1e-124 | 72.22% (306) | O-methyltransferase |
| M. avium 104 | MAV_4441 | - | 1e-108 | 64.05% (306) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_1482 | - | 1e-101 | 60.93% (302) | methyltransferase |
| M. thermoresistible (build 8) | TH_0301 | - | 7e-85 | 57.61% (276) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0818 | - | 1e-101 | 59.24% (314) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1346 | - | 3e-95 | 57.47% (308) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0731c|M.tuberculosis_H37Rv MTQTGSARFEGDSWDLASSVGLTATMVAAARAVAGRAP---GALVNDQFA
Mb0752c|M.bovis_AF2122/97 MTQTGSARFEGDSWDLASSVGLTATMVAAARAVAGRAP---GALVNDQFA
MMAR_1069|M.marinum_M ---MSSARFDGDTWDLASSVGLTATMVAAARAVAARDPEGAGAVATDRFA
MAV_4441|M.avium_104 MTST---RYEGDTWDLASSVGVTATMVAAARAMATRAD---NPLINDPFA
MUL_0818|M.ulcerans_Agy99 MTSTGSTRYDGDSWDLASSVGVTATMVAAARAMATRAE---NPLINDPYA
Mflv_5023|M.gilvum_PYR-GCK -----MPRTENDTWDLASSVGATATMVAAARAVATRAE---DPVIDDPYA
Mvan_1346|M.vanbaalenii_PYR-1 -----MARTDNDTWDLASSVGATATMVAAARAVATRAP---RPVIDDPFA
MSMEG_1482|M.smegmatis_MC2_155 -----MARTENDTWDLASSVGATATMVAAARALATNAD---EPAIDDPFA
TH_0301|M.thermoresistible__bu -----MX-------------GG-----------ASRDP---KELINDPFA
MAB_3787|M.abscessus_ATCC_1997 -----MARTDDDSWDLASSVGATATMVAAQRALASHVP---NPLINDPYA
MLBr_02640|M.leprae_Br4923 ------MRTHDDTWDIKTSVGTTAVMVAAARAAETDRP---DALIRDPYA
* * :*
Rv0731c|M.tuberculosis_H37Rv EPLVRAVGVDFFVRMASGELDPDELA------EDEANGLRRFADAMAIRT
Mb0752c|M.bovis_AF2122/97 EPLVRAVGVDFFVRMASGELDPDELA------EDEANGLRRFADAMAIRT
MMAR_1069|M.marinum_M EPLVRAVGVDFFTRMATGELDAAELD------EETAIGMRHFGAAMAIRT
MAV_4441|M.avium_104 EPLVKAVGVDLLSRLAGGELDPAELNDVHDGAAGSAGAMSRMADNMAVRT
MUL_0818|M.ulcerans_Agy99 EPLVRAVGVDLLTRLATGEFNVADLD---DDPQRPLGPIGDVADNMAVRT
Mflv_5023|M.gilvum_PYR-GCK EPLVRAVGIDFFAKLASGELTPEDLDVS---GDESPVGMSRFADGMAART
Mvan_1346|M.vanbaalenii_PYR-1 APLVQAVGVDFFTRLATGELTTEELDTN---DAESPVGMSRFADAMAART
MSMEG_1482|M.smegmatis_MC2_155 APLVRAVGVDFFTKLVDDNFDLTALDP------EAAEGLTRFANGMAART
TH_0301|M.thermoresistible__bu APLVRAVGIDFFTRIADGELTVADLDP------QSAPRVQANIDEVAVRT
MAB_3787|M.abscessus_ATCC_1997 EPLVRAVGIEYFTKLASGAFDPEQMAG----LVQLGITADGMANGMASRT
MLBr_02640|M.leprae_Br4923 KLLVTNTGAGALWEAMLDPSMVAKVEAID---AEAAAMVEHMRSYQAVRT
** .* : . . : * **
Rv0731c|M.tuberculosis_H37Rv HYFDNFFLDATRAG---IRQAVILASGLDSRAYRLRWPAGTIVFEVDQPQ
Mb0752c|M.bovis_AF2122/97 HYFDNFFLDATRAG---IRQAVILASGLDSRAYRLRWPAGTIVFEVDQPQ
MMAR_1069|M.marinum_M RFFDDFFLDATASG---IRQAVILASGLDSRAYRLPWPAGTTLFEVDQPK
MAV_4441|M.avium_104 KFFDEFFLNATKAG---IAQVVILASGLDARAYRLAWPAGTVVYEVDQPQ
MUL_0818|M.ulcerans_Agy99 RFFDDFFLAATRAG---LEQVVILASGRDARAYRLPWPPQTVVYEIDLPQ
Mflv_5023|M.gilvum_PYR-GCK RFFDDFFTDACAAG---VRQAVILASGLDARGYRLTWPEGMTLFEIDQPE
Mvan_1346|M.vanbaalenii_PYR-1 RFFDDFFAEAMRAGPPPIRQGVILASGLDARAYRLSWPQDMVLFEIDQPE
MSMEG_1482|M.smegmatis_MC2_155 RFFDDFFLDAARAG---VRQFVILASGLDARAYRLPWPAGSVVFEIDQPD
TH_0301|M.thermoresistible__bu RFFDDHFAAATARG---IRQAVILAAGLDARAYRLRWPDGTVVYEIDQPR
MAB_3787|M.abscessus_ATCC_1997 WYYDTAFESSTAAG---VRQAVILASGLDTRAYRLTWPAGTTVYELDQPE
MLBr_02640|M.leprae_Br4923 NFFDTYFNNAVIDG---IRQFVILASGLDSRAYRLDWPTGTTVYEIDQPK
::* * : * : * ****:* *:*.*** ** ::*:* *
Rv0731c|M.tuberculosis_H37Rv VIDFKTTTLAGLGAAPTTDRRTVAVDLRDDWPTALQKAGFDNAQRTAWIA
Mb0752c|M.bovis_AF2122/97 VIDFKTTTLAGLGAAPTTDRRTVAVDLRDDWPTALQKAGFDNAQRTAWIA
MMAR_1069|M.marinum_M VIDFKIATLSELGAQPTADRRAVAVDLREDWPAALRQAGFDPTERTAWIA
MAV_4441|M.avium_104 VIDFKTTALAQLGAAPTAERRVVAVDLRDDWPAALRAAGFDPTRPTAWSA
MUL_0818|M.ulcerans_Agy99 VIDFKSRTLADLGAAPTADRRVVAVDLREDWPAALRAAGFDPNQPTAWSA
Mflv_5023|M.gilvum_PYR-GCK VIEFKRTTLAGLGATPSTHLATVAIDLREDWPTALRDAGFDPSVPTAWIA
Mvan_1346|M.vanbaalenii_PYR-1 VLTFKAATLADLGVRPSTKLATVAVDLRNDWPAALAEAGFDASAPTAWIA
MSMEG_1482|M.smegmatis_MC2_155 VIEFKTKALADLGALPTTDRRAVAVDLRFDWPAALTEAGFDPAEPTAWIA
TH_0301|M.thermoresistible__bu VIEFKTRTLARLGAEPTAERRTVAADLRHDWPAALTAAGFDPAAPTVWIA
MAB_3787|M.abscessus_ATCC_1997 VITFKTDTLAELGASPSAERRTVAIDLREDWPAALQAAGFDPEQPTVWSA
MLBr_02640|M.leprae_Br4923 VLAYKSTTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLA
*: :* :*: *. *::. *. *** ***.** **** *.* *
Rv0731c|M.tuberculosis_H37Rv EGLLGYLSAEAQDRLLDQITAQSVPGSQFATEVLRDINRLNEEELRGRMR
Mb0752c|M.bovis_AF2122/97 EGLLGYLSAEAQDRLLDQITAQSVPGSQFATEVLRDINRLNEEELRGRMR
MMAR_1069|M.marinum_M EGLLGYLPAEAQDRLLDQIAAQSAAGSRFATEGLPDVNDVKQEELRRRMQ
MAV_4441|M.avium_104 EGLLGYLPPEAQDRLLDTITELSAPGSRLATESAPNPAPGEEEKLKERMQ
MUL_0818|M.ulcerans_Agy99 EGLLGYLPPEAQDRLLDTVTELSAPGSRLAAECLSGVDPAEEEQIKERMQ
Mflv_5023|M.gilvum_PYR-GCK EGLLGYLPPDAQDRLLDTIGELSASGSRLAVESVPSQQSADQDEMREKMK
Mvan_1346|M.vanbaalenii_PYR-1 EGLLGYLPPDAQDRLLDTIGELSAPGSRLAVESVPTHHEADQEELREKMK
MSMEG_1482|M.smegmatis_MC2_155 EGLLGYLPPEAQDRLLDQIAELSAPGSRVAVEEIPAIEEEDHEEIAARMK
TH_0301|M.thermoresistible__bu EGLFGYLPPDAQDRLLDQITDLSAVGSRLGVEGVPAHADADEDEVRQRMR
MAB_3787|M.abscessus_ATCC_1997 EGLLIYLPPEAQDRLFASITELSAPGSRLVCEQVPGLETADFS----KAR
MLBr_02640|M.leprae_Br4923 EGLLMYLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFR
***: **.. *** *: : *. **:. * . : :
Rv0731c|M.tuberculosis_H37Rv RLAERFRRHGLDLDMSGLVYFGD-RTDARTYLADHGWRTASASTTDLLAE
Mb0752c|M.bovis_AF2122/97 RLAERFRRHGLDLDMSGLVYFGD-RTDARTYLADHGWRTASASTTDLLAE
MMAR_1069|M.marinum_M RQNERWNRHGFDLDMAALVYFDD-RTDAGTYLAAQGWQVTSASNSELFTQ
MAV_4441|M.avium_104 AISQRWRAHGFDLDMAGLVYFGE-RNEAAPYLAGHGWRLNSVTIRDLFAA
MUL_0818|M.ulcerans_Agy99 EVSARWRAHGFDVDMVGLVYFGD-RNEAVPYLSDRGWLLTSTPLPELRAA
Mflv_5023|M.gilvum_PYR-GCK DSTDRWRSHGFDLDFSELVFLGE-RANVPDYLRERGWAVTATPTNDLLTR
Mvan_1346|M.vanbaalenii_PYR-1 ESSDRWRSHGFDVDFSELVFLGE-RADVTDYLRDRGWTVDATPTNQLLTR
MSMEG_1482|M.smegmatis_MC2_155 DFSDRWRAHGFDLDFTELVFLGD-RADVSSYLQGHGWKTTSMTSDELLVH
TH_0301|M.thermoresistible__bu ILAERWRAHGLDLDFSELIYLGD-RADVAGYLADRGWRCTALTANELLVR
MAB_3787|M.abscessus_ATCC_1997 ELTRQFAGETLDLDLESLVYTQE-RQMAADWLAEHGWTVITEENDELYAR
MLBr_02640|M.leprae_Br4923 RVSDALG-FEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRR
:*. *:: : * . :* :** : :
Rv0731c|M.tuberculosis_H37Rv HG-----LPPID-GDDAPFGEVIYVSAELKQKHQDTR--
Mb0752c|M.bovis_AF2122/97 HG-----LPPID-GDDAPFGEVIYVSAELKQKHQDTR--
MMAR_1069|M.marinum_M HG-----LQPLN-GDDAPFGEVLYLSAVKDTAAAA----
MAV_4441|M.avium_104 NG-----LDPLD-DDDTRMGEMLYTWG-IYE--------
MUL_0818|M.ulcerans_Agy99 NG-----LAPAAVDDDGPSVDMLYVSGTLYTTPRPDPAP
Mflv_5023|M.gilvum_PYR-GCK YG-----LAPLD--TDEGFAEVVYVNAAR----------
Mvan_1346|M.vanbaalenii_PYR-1 YG-----LAPLD--SDEGFAEVVYVSATR----------
MSMEG_1482|M.smegmatis_MC2_155 NG-----LPRVD--DDAQIGSVVYVTATR----------
TH_0301|M.thermoresistible__bu TG-----LPPAE--NDGRVTEVVYLSSEKSPGKRAG---
MAB_3787|M.abscessus_ATCC_1997 LN-----LDPPNPLLRSIFPNIVYVDATLG---------
MLBr_02640|M.leprae_Br4923 VGRWGDGVPMAD--DKDAFAEFVTAHRL-----------
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