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M. tuberculosis H37Rv Rv0532 (PE_PGRS6)

annotation: PE-PGRS FAMILY PROTEIN
coordinates: 622793 - 624577
length: 594

MSNLLVTPELVAAAAADLAGIGSAIGAANAAAGAPTMALLAAGADEVSAAVAAVFSSYAQQYQALSAAAA
AFHDQFVRALAAGAGAYAGAEAANVEQQLLNAINAPTLALLGRPLIGNGADGAAGTGQAGGAGGLLYGNG
GNGGSGAAGQAGGAGGAAGLIGHGGTGGAVTGVSTTGGPGGHGGDAGLYGFGGAGGAGGFGQSGAAGGAG
GAGGWLYGDGGDGGAGDNGGNESGTGVSAVGGVGGAGGAGGLLFGNGGDGGVGGDGGDGSSTQDSGGDGG
AGGAGGAGGWLLGNGGAGGAGGAASIKVATGGLGGDGGDAGLFGFGGDGGWGGRGVDARFGAAGGAAGAG
GAGGWLYGDGGAGGVGGVGGAVFSLSSGDGGAGGAGGGGGWLFGNGGDGGAGGGGGGRFGSGSGAGGDGA
VGGAGGAGAWFGNGGAGGVGGGGGRGTTAIGGDGGAGGAGGAGGWLYGDGGAGGAGGGGGRGGTGNDGGD
GGDGGRGGDAQLLGNGGDGGAGGAGGPAGLALPPGPARPAGAAVPAVRCSAAPARPARTADPWLAPIFAR
STLRHSHHLGGIAQTGAVADQQGQIAGLGRAGRQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0532PE_PGRS6-100% (594)PE-PGRS FAMILY PROTEIN
M. tuberculosis H37RvRv1396cPE_PGRS25e-16657.07% (594) PE-PGRS family protein
M. tuberculosis H37RvRv2162cPE_PGRS38e-16059.93% (534) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0545PE_PGRS6a0.092.53% (562) hypothetical protein Mb0545
M. gilvum PYR-GCKMflv_5091-1e-10244.93% (552) triple helix repeat-containing collagen
M. leprae Br4923MLBr_01183-5e-1239.08% (87) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-1e-4037.14% (385) hypothetical protein MAB_4284c
M. marinum MMMAR_2645-1e-15553.81% (617) PE-PGRS family protein
M. avium 104MAV_4827-2e-2243.37% (166) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-5e-7337.90% (591) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-1e-4039.03% (351) PUTATIVE -
M. ulcerans Agy99MUL_3292-1e-15353.38% (607) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-5e-9541.64% (634) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Rv0532|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0545|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2645|M.marinum_M               --------------------------------------------------
MUL_3292|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv0532|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0545|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2645|M.marinum_M               --------------------------------------------------
MUL_3292|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv0532|M.tuberculosis_H37Rv         ---------------------------------------MSNLLVTP---
Mb0545|M.bovis_AF2122/97            ---------------------------------------MSNLLVTP---
MMAR_2645|M.marinum_M               ---------------------------------------MSYLIAAP---
MUL_3292|M.ulcerans_Agy99           ---------------------------------------MSYVIAAP---
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923          ---------------------------------------MPLFLNAEP--
MAV_4827|M.avium_104                ---------------------------------------MNIVLGVSMAP
                                                                                      

Rv0532|M.tuberculosis_H37Rv         ----------------------------------------ELVAAAAADL
Mb0545|M.bovis_AF2122/97            ----------------------------------------ELVAAAAADL
MMAR_2645|M.marinum_M               ----------------------------------------EMVAAAATDL
MUL_3292|M.ulcerans_Agy99           ----------------------------------------EMLAGAATDL
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------VEAASYVADP
MLBr_01183|M.leprae_Br4923          ----------------------------------------QALTAAANTL
MAV_4827|M.avium_104                ----------------------------------------SSIQMVVLEG
                                                                                      

Rv0532|M.tuberculosis_H37Rv         AG---------------------------------------IGSAIGAAN
Mb0545|M.bovis_AF2122/97            AG---------------------------------------IGSAIGAAN
MMAR_2645|M.marinum_M               AS---------------------------------------VGSSISAAN
MUL_3292|M.ulcerans_Agy99           AG---------------------------------------IGAALQSAN
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      EAA-------------------------------------LANAGLSAVS
MLBr_01183|M.leprae_Br4923          EG---------------------------------------LSAATVASN
MAV_4827|M.avium_104                EYAD--------------------------------------GATVEEDA
                                                                                      

Rv0532|M.tuberculosis_H37Rv         AAAGAPTMALLAAGADEVSAAVAAVFSSYAQQYQALSAAAAAFHDQFVRA
Mb0545|M.bovis_AF2122/97            AAAGAPTMALLAAGADEVSAAVAAVFSSYAQQYQALSAAAAAFHDQFVRA
MMAR_2645|M.marinum_M               AAAAAPTMSVLAAGADEVSAVVAALFDAHAQAYQSLSAQAALFHEQFVQA
MUL_3292|M.ulcerans_Agy99           GAAAAPITGVLAAGADEISAAVAALFSGHALDYQALSTQMAGFHQQFVTA
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu      ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199      AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQNYYAAQ
MLBr_01183|M.leprae_Br4923          AAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQS
MAV_4827|M.avium_104                IDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAA
                                                                                      

Rv0532|M.tuberculosis_H37Rv         LAAGAGAYAGAEAANVE------QQLLNAINAPTLALLGRPLIGN--GAD
Mb0545|M.bovis_AF2122/97            LAAGAGAYAGAEAANVE------QQLLNAINAPTLALLGRPLIGN--GAD
MMAR_2645|M.marinum_M               LNAGAGSYALAEAASVSPL----QDALNLINAPTQALFGRPLIGN--GAD
MUL_3292|M.ulcerans_Agy99           LNSAGASYAAAEAASANPLQAVEQQLLGVINAPTQALLGRPLIGD--GTA
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGA--TGA
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGA--TGA
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGT--GGG
TH_3810|M.thermoresistible__bu      GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGH--GGG
MAB_4284c|M.abscessus_ATCC_199      PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGN--VDS
MLBr_01183|M.leprae_Br4923          LLTSSSAYAGTETANHDSL-------------------------------
MAV_4827|M.avium_104                ALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTAT
                                                                                      

Rv0532|M.tuberculosis_H37Rv         GAAGTGQAGGAGGLLYGNGGNGGSG-AAGQAGGAGGA-------------
Mb0545|M.bovis_AF2122/97            GAAGTGQAGGAGGLLYGNGGNGGSG-AAGQAGGAGGA-------------
MMAR_2645|M.marinum_M               GAPGTGQSGGNGGFLYGNGGNGGSG-ANNQGGGNGGS-------------
MUL_3292|M.ulcerans_Agy99           GAP--GQNGGDGGLLWGNGGAGGVGTAAHPTGGSGGS-------------
Mflv_5091|M.gilvum_PYR-GCK          TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1       TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155      TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPN
TH_3810|M.thermoresistible__bu      TGIIS--------------------LLSLAGNGGNGG-------------
MAB_4284c|M.abscessus_ATCC_199      FNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSG-------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                LAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAG-------------
                                                                                      

Rv0532|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0545|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2645|M.marinum_M               --------------------------------------------------
MUL_3292|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG----
Mvan_1264|M.vanbaalenii_PYR-1       -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG----
MSMEG_0868|M.smegmatis_MC2_155      VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv0532|M.tuberculosis_H37Rv         ----------AGLIGHGGTG----------------------------GA
Mb0545|M.bovis_AF2122/97            ----------AGLIGHGGTGGVGGTGAAGGAGGTGGWLFGNGGAGGTGGA
MMAR_2645|M.marinum_M               ----------AGLWGNGGAGG-------------------------AGGD
MUL_3292|M.ulcerans_Agy99           ----------AGLIGTGGAGG------------------------AGYGP
Mflv_5091|M.gilvum_PYR-GCK          ---AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGG
Mvan_1264|M.vanbaalenii_PYR-1       ---VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGT
MSMEG_0868|M.smegmatis_MC2_155      GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG
TH_3810|M.thermoresistible__bu      ----------NGYRTTDNNALDGGHGGNG-----------------GNVG
MAB_4284c|M.abscessus_ATCC_199      ----------PIASGQGSTAVNGDVRDSN-----IINADHGSNVGVDQSQ
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------LEKLESLPGGLLLVGSG-------------------VDVAP
                                                                                      

Rv0532|M.tuberculosis_H37Rv         VTGVSTTGGPGGHGGDAG----------------LYGFGGAGGAGG----
Mb0545|M.bovis_AF2122/97            VTGVSTTGGPGGHGGDAG----------------LYGFGGAGGAGG----
MMAR_2645|M.marinum_M               STVAGVNGFNGGAGGSGGL---------------LWGNGGAGGAGGNGGG
MUL_3292|M.ulcerans_Agy99           AAQTGATGGSGGVGGTGG--------------------SGLDGPDS----
Mflv_5091|M.gilvum_PYR-GCK          LGETGTTG---GAGGVG--------------------GQGTAGGTGGVGG
Mvan_1264|M.vanbaalenii_PYR-1       AGETGVTG---GVGGIG--------------------GQGTEGGTGGVGG
MSMEG_0868|M.smegmatis_MC2_155      HSTGTGIG---GNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGG
TH_3810|M.thermoresistible__bu      FFSLFNLG---GAGGWG--------------------GSGVDG-------
MAB_4284c|M.abscessus_ATCC_199      TRVGGDYTNVSGHG-----------------------SADIDKSVTVVDD
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                LKQVLQTTTFLDVSVAEEP-----------------ETALARGAALAAAN
                                                                                      

Rv0532|M.tuberculosis_H37Rv         ----------------FGQSGAA---------------------------
Mb0545|M.bovis_AF2122/97            ----------------FGQSGAA---------------------------
MMAR_2645|M.marinum_M               AP-------------LAGFVGTS---------------------------
MUL_3292|M.ulcerans_Agy99           -----------------GAAGGA---------------------------
Mflv_5091|M.gilvum_PYR-GCK          IGGAG----------STGAVGG-------VGGKG----IQGGQG------
Mvan_1264|M.vanbaalenii_PYR-1       VGGVG----------ATGGAGG-------VGGKG----IQGGQG------
MSMEG_0868|M.smegmatis_MC2_155      MGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGK
TH_3810|M.thermoresistible__bu      ----------------VDVVGG----------------------------
MAB_4284c|M.abscessus_ATCC_199      HSQRN----------TTNINDS----------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AP-------------LFASSTAALAY------------------------
                                                                                      

Rv0532|M.tuberculosis_H37Rv         ------------GGAGGAG---GWLYG---------------------DG
Mb0545|M.bovis_AF2122/97            ------------GGAGGAGGAGGWLYG---------------------DG
MMAR_2645|M.marinum_M               ------------GGNGGNGGGAGLLYG---------------------YG
MUL_3292|M.ulcerans_Agy99           ------------GGSGGSGG-AARLFG---------------------NG
Mflv_5091|M.gilvum_PYR-GCK          -------LQGGKGGDGGAGGKGGDADSMGS------------------AG
Mvan_1264|M.vanbaalenii_PYR-1       -------LQGGQGGDGGTGGTGGDATSMGE------------------AG
MSMEG_0868|M.smegmatis_MC2_155      ASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAAS
TH_3810|M.thermoresistible__bu      ------------NPDGGTPG------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------FNTDRSTNIGSGNTTNTEIGSHN------------------QA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------AQDPGTGAVDQYSLPDYLYVPVDPE-------PGDDEL
                                                                                      

Rv0532|M.tuberculosis_H37Rv         GDGGAGDNGGNESGTGVS--------------------------------
Mb0545|M.bovis_AF2122/97            GDGGAGGNGGNESGTGVS--------------------------------
MMAR_2645|M.marinum_M               GAGGAGGTGGVAPPTGVGQTIL----------------------------
MUL_3292|M.ulcerans_Agy99           GAGGSGGKGGNGGSAIET--------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD------
Mvan_1264|M.vanbaalenii_PYR-1       ATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN------
MSMEG_0868|M.smegmatis_MC2_155      ANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAY
TH_3810|M.thermoresistible__bu      AHGESHTPGVYTDRQ-----------------------------------
MAB_4284c|M.abscessus_ATCC_199      NIGTSTSAGGSAAVGGNAG-------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AYSAVGEEDAESPTVVIEK-------------------------------
                                                                                      

Rv0532|M.tuberculosis_H37Rv         -----------------AVGGVGGAGGAGGLLFGNGGDGG----------
Mb0545|M.bovis_AF2122/97            -----------------GVGGVGGAGGAGGLLFGNGGDGG----------
MMAR_2645|M.marinum_M               --------------SAGGVGGTGGAGGGGAALIGFGGAGG----------
MUL_3292|M.ulcerans_Agy99           -----------------GNDGAAGAGGHGGWLVGNGGIGG----------
Mflv_5091|M.gilvum_PYR-GCK          ----------------GGTGGAGGAGGTGG-TGGAGGTGG----------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------GGTGGNGGNGGTGG-TGGNGGTGG----------
MSMEG_0868|M.smegmatis_MC2_155      DPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQ
TH_3810|M.thermoresistible__bu      --------------------GEDGEDGTGTGIGGRGGNGG----------
MAB_4284c|M.abscessus_ATCC_199      ------------------LAGNAGLAGNAGLAGNAGLAGN----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------LFLPEDSEPRRRPVLLVGSGLAVV----------
                                                                                      

Rv0532|M.tuberculosis_H37Rv         -------VGGDGG-DGSSTQD-------SGGDGGAGGAG-----GAGGWL
Mb0545|M.bovis_AF2122/97            -------VGGDGG-DGSSTQD-------SGGDGGAGGAG-----GAGGWL
MMAR_2645|M.marinum_M               -------TGGTGGLSDTTTET-------IGGYGGMGGLG-----GQSGVL
MUL_3292|M.ulcerans_Agy99           -------DGGSGGVGGDAGAYGPPANGGAGGHGGMGGVG-----GDAGLL
Mflv_5091|M.gilvum_PYR-GCK          -------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       -------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155      HSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE--GEGGTGGH
TH_3810|M.thermoresistible__bu      ------SSSGTHPMAEDG--------EHVKALDGRPGLD-----GGNGSH
MAB_4284c|M.abscessus_ATCC_199      -----AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------GISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAPAP
                                                                                      

Rv0532|M.tuberculosis_H37Rv         LGNGGAGGAGGAASIK-VAT--------GGLGGDGGDAG---LFG---FG
Mb0545|M.bovis_AF2122/97            LGNGGAGGAGGAASIK-VAT--------GGLGGDGGDAG---LFG---FG
MMAR_2645|M.marinum_M               FGTPGAGGAGGAGGAG-VGTF----ASPGGHGGSGGDAGAIGLFGNGAAG
MUL_3292|M.ulcerans_Agy99           FGSGGAGGVGGNGAIGGTGVM----SGAGGAGGDGGNGGYAQLIG---DG
Mflv_5091|M.gilvum_PYR-GCK          GGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTG
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTG
MSMEG_0868|M.smegmatis_MC2_155      GGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAG
TH_3810|M.thermoresistible__bu      GGNGGHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TD
MAB_4284c|M.abscessus_ATCC_199      AGNAGLAGNAGLAGNAGLAG----NAGLAGNAGLAGNAG--------LAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIP
                                                                                      

Rv0532|M.tuberculosis_H37Rv         GDGGWGG------------RGVDARFGAAGG-------------------
Mb0545|M.bovis_AF2122/97            GDGGWGG------------RGVDARFGAAGG-------------------
MMAR_2645|M.marinum_M               GDGGIGGD--------GASGGNDGGNGGVGG-------------------
MUL_3292|M.ulcerans_Agy99           GGGGAGGAGY------SASGLPPAGIGAPGG-------------------
Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEAL
TH_3810|M.thermoresistible__bu      ADGGNGGDG---------------GNGGSAG-------------------
MAB_4284c|M.abscessus_ATCC_199      NAGLAGNAG-------------LAGNAGLAG-------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AAPPVVPVP---------VVVPPVPVPVPVR-------------------
                                                                                      

Rv0532|M.tuberculosis_H37Rv         --------------AAGAGGAGGWLYGDGGAG------------------
Mb0545|M.bovis_AF2122/97            --------------AAGAGGAGGWLYGDGGAG------------------
MMAR_2645|M.marinum_M               --------------LGGVGGPGGWIFGTGGAG------------------
MUL_3292|M.ulcerans_Agy99           --------------AGGAGGSGGWLVGNGGAG------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------TGGTGGQGG-LGGGGGTG------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------TGGTGGQGG-LGGVGGTG------------------
MSMEG_0868|M.smegmatis_MC2_155      IRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQAS
TH_3810|M.thermoresistible__bu      --------------RGGTGGLRGVFGINGGNG------------------
MAB_4284c|M.abscessus_ATCC_199      --------------NAAVAGNAAVAGNAAVAG------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------IPVPDPVSPPQLLAPPRLSVP-----------------
                                                                                      

Rv0532|M.tuberculosis_H37Rv         -----GVGGVGGAVFS--LSSGDGGAGGAG--------GGGG--WLFGNG
Mb0545|M.bovis_AF2122/97            -----GVGGVGGAVFS--LSSGDGGAGGAG--------GGGG--WLFGNG
MMAR_2645|M.marinum_M               -----GNGGLGGSGGTGVVTNGFAGSGGFG--------GAGGDAQFLGFG
MUL_3292|M.ulcerans_Agy99           -----GIGGIGASGSFG-APSGQGGNGGIG--------GAAG---LFGQG
Mflv_5091|M.gilvum_PYR-GCK          -----GQGGTGGTGGQG-GTGGTGGTGGTG--------GTGGAGGDGGLG
Mvan_1264|M.vanbaalenii_PYR-1       -----GTGGTGGTGGQG-GTGGTGGTGGTG--------GTGGAGGDGGLG
MSMEG_0868|M.smegmatis_MC2_155      GTATDGHGGSGINGGHG-GNGGQGTIEANGPSAVASGIGAGGNGGDGIDG
TH_3810|M.thermoresistible__bu      ------RAGLGGRGXXX-XGGGVGAAVRSG---------------NGVFS
MAB_4284c|M.abscessus_ATCC_199      ------NAAVGGVLNTG-VSGAIGGSSHVG---------GAINESLGGSG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----QPVQPPVRVPQPPSPPQVGGTVPQS------------PPQHQTPP
                                                                                      

Rv0532|M.tuberculosis_H37Rv         GDGGAGG--GGGGRFGSGSGAGGDGAVGGAGG------------------
Mb0545|M.bovis_AF2122/97            GDGGAGG--GGGGRFGSGSGAGGDGAVGGAGG------------------
MMAR_2645|M.marinum_M               GTGGSGGGIGAGETAAVPLTTQPVGGTGGNGGR-----------------
MUL_3292|M.ulcerans_Agy99           GAGGNGGQ-GGGDDFALSGGAGGAGGAGGHGG------------------
Mflv_5091|M.gilvum_PYR-GCK          GLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----
Mvan_1264|M.vanbaalenii_PYR-1       GLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----
MSMEG_0868|M.smegmatis_MC2_155      GLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWV
TH_3810|M.thermoresistible__bu      GGGGTPSAGFGVPTTIQFPAGSCTSRAVSREG------------------
MAB_4284c|M.abscessus_ATCC_199      SVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGG------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GEGTPPKPDGPGNYGGGHVPTPGAGGSGGSGGG-----------------
                                                                                      

Rv0532|M.tuberculosis_H37Rv         ---AGAWFGNGGAGGVG------------GGGGR--------------GT
Mb0545|M.bovis_AF2122/97            ---AGAWFGNGGAGGVG------------GGGGR--------------GT
MMAR_2645|M.marinum_M               ---AGLFFGVGGTGGNGGATSTNGALYATGGNGG--------------DG
MUL_3292|M.ulcerans_Agy99           -----QLYGDGGGGGAG------------GMGGSV----------DIAES
Mflv_5091|M.gilvum_PYR-GCK          GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGA
Mvan_1264|M.vanbaalenii_PYR-1       GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGA
MSMEG_0868|M.smegmatis_MC2_155      QSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGN
TH_3810|M.thermoresistible__bu      ------IMPSSRAASARAG---------------------------AACA
MAB_4284c|M.abscessus_ATCC_199      --GISESLGGSGSVGGSTAVGGGAHTGVGGGVS----------TGVGVGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---HVPTPGAGGSGGSGG------------------------------GH
                                                                                      

Rv0532|M.tuberculosis_H37Rv         TAIGGDGGAGGAGGAGG-------------WLYGDGGAGGAG-----GGG
Mb0545|M.bovis_AF2122/97            TAIGGDGGAGGAGGAGG-------------WLYGDGGAGGAG-----GGG
MMAR_2645|M.marinum_M               GLIFGNGGTGGNGGAGGG------------TSVGAGGQGGAAS-AFFGNG
MUL_3292|M.ulcerans_Agy99           GVTGGRGGSGSVGGGAG--------------LWGAGGQGGDGAQGGDGGA
Mflv_5091|M.gilvum_PYR-GCK          AGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANG
Mvan_1264|M.vanbaalenii_PYR-1       SGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANG
MSMEG_0868|M.smegmatis_MC2_155      TATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNG
TH_3810|M.thermoresistible__bu      SSTSRSRRSFCCSRA-----------------------------------
MAB_4284c|M.abscessus_ATCC_199      HVGGGISESLGGSGSVGGSTAVG---------GGAHTGVGGGVNTGVGVG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VPTPGTGGPGGTGGSGG----------------GHVPTPGAGTPGGSGGG
                                                                                      

Rv0532|M.tuberculosis_H37Rv         GRGGTGNDGGDGGDGGRGGD-AQLLGNGGDGGAG-------GAGGPAGLA
Mb0545|M.bovis_AF2122/97            GRGGTGNDGGDGGDGGRGGD-AQLLGNGGDGGAG-------GAGGPAGFG
MMAR_2645|M.marinum_M               GAGGDGGAGGQGAGGAGGSG-ALFFGNGGAGGNG-------APGG-TGVG
MUL_3292|M.ulcerans_Agy99           GVDTTTGAGGDGGAGAGGGTSGFLYGNGGAGGAGGHGGGGPGMGGDGGDG
Mflv_5091|M.gilvum_PYR-GCK          SQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1       SQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155      GKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SHVGGGISESLGGSGSVG-------GSTAVGGGAHTSAINDALGGSGSVG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                HLPFPGAGSTPGGSGGGHLP------TPGAGTPG---------GGLGGFG
                                                                                      

Rv0532|M.tuberculosis_H37Rv         L-----------PPGPARPAGAAVPAVRCSAAPARPARTADPWLAPIFAR
Mb0545|M.bovis_AF2122/97            A-----------SPG----AGAAG--------------------------
MMAR_2645|M.marinum_M               G-----------TGGSAVLIGNGGD-------------------------
MUL_3292|M.ulcerans_Agy99           G-----------DGGRAQLIGTGGNG------------------------
Mflv_5091|M.gilvum_PYR-GCK          G-----------AGGEGGEGGDGGKGGAGAE--------GGAGG------
Mvan_1264|M.vanbaalenii_PYR-1       G-----------AGGEGGEGGAGGAGGDGSE--------GGAGG------
MSMEG_0868|M.smegmatis_MC2_155      GNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGG------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      G----------STAVGGGAHTSAINESMNSSINASHSSSMNESF------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                G-----------GHAPAPGGGLGGGG------------------------
                                                                                      

Rv0532|M.tuberculosis_H37Rv         STLRHSHHLGGIAQTG---AVADQQGQ----IAGLGRAGRQ-----
Mb0545|M.bovis_AF2122/97            ---------GGGGAGG---SLFGSPGT----TGPHG----------
MMAR_2645|M.marinum_M               ---------GGDGTGG---AAGGAGGSGGFIFGQNGSNGLP-----
MUL_3292|M.ulcerans_Agy99           -------GAGGTAAPGGTDGTAGAAGKGGVLFGTDGATG-------
Mflv_5091|M.gilvum_PYR-GCK          -----GGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1       -----SGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155      -----NGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu      ----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----GSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH---
MLBr_01183|M.leprae_Br4923          ----------------------------------------------
MAV_4827|M.avium_104                ---------GHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-------