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MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPVTGQPFCEVPRSDAADIDKALDAAHAAA PGWGKTAPAERAAILNMIADRIDKNAAALAVAEVWDNGKPVREALAADIPLAVDHFRYFAAAIRAQEGAL SQIDEDTVAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPASVLYLMSLIGDLLP PGVVNVVNGFGAEAGKPLASSDRIAKVAFTGETTTGRLIMQYASHNLIPVTLELGGKSPNIFFADVLAAH DDFCDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDTETMLGSQASNDQL EKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNMRIFKEEIFGPVVAVTSFTDYDDA IGIANDTLYGLGAGVWSRDGNTAYRAGRDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGREGHQMMLQHYQ HTKNLLVSYSDKALGFF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0458 | - | - | 100% (507) | PROBABLE ALDEHYDE DEHYDROGENASE |
| M. tuberculosis H37Rv | Rv0223c | - | 1e-70 | 36.49% (485) | aldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv2858c | aldC | 9e-69 | 35.62% (466) | aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0467 | - | 0.0 | 100.00% (507) | aldehyde dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4952 | - | 0.0 | 84.22% (507) | aldehyde dehydrogenase |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 2e-51 | 31.46% (445) | succinic semialdehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2792c | - | 0.0 | 79.88% (507) | aldehyde dehydrogenase |
| M. marinum M | MMAR_0780 | putA_1 | 0.0 | 90.34% (507) | aldehyde dehydrogenase, PutA_1 |
| M. avium 104 | MAV_4691 | - | 0.0 | 89.35% (507) | eptc-inducible aldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0900 | - | 0.0 | 86.59% (507) | eptc-inducible aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3284 | - | 0.0 | 87.65% (494) | PUTATIVE eptc-inducible aldehyde dehydrogenase |
| M. ulcerans Agy99 | MUL_1416 | - | 0.0 | 89.35% (507) | aldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1468 | - | 0.0 | 84.62% (507) | aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0458|M.tuberculosis_H37Rv MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPVTGQPFCE
Mb0467|M.bovis_AF2122/97 MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPVTGQPFCE
MMAR_0780|M.marinum_M MTVFARPGSAGALMSFESRYGNFIGGEWVAPARGRYFEDLTPVTGQPFCE
MUL_1416|M.ulcerans_Agy99 MTVFARPGSAGALMSFESRYGNLIGGEWVAPARGRYFEDLTPVTGQPFCE
MAV_4691|M.avium_104 MTVFARPGSAGALMSYESRYDNFIGGQWVAPARGRYFENPTPVTGQTFCE
Mflv_4952|M.gilvum_PYR-GCK MTVYARPGADGSLMSFKPRYDNFIGGQWVAPTAGRYFENPSPVTGQPFTE
Mvan_1468|M.vanbaalenii_PYR-1 MTVYARPGADGSLMSFKPRYDNFIGGQWVAPNAGRYFENPSPVTGQPFTE
TH_3284|M.thermoresistible__bu -------------MSFESRYDNFIGGEWVAPVGGEYFENPSPVTGQPFCE
MSMEG_0900|M.smegmatis_MC2_155 MTVFSRPGAADARMSFESRYDNFIGGEWVAPVDGRYFENPTPVTGQVFCE
MAB_2792c|M.abscessus_ATCC_199 MTVYARPGAQGSLMTFASRYENFIGGQWVPPEHGRYFENRTPVTGEVFCE
MLBr_02573|M.leprae_Br4923 ----------------------------------MSIATINPATGETVKT
: .*.**: .
Rv0458|M.tuberculosis_H37Rv VPRSDAADIDKALDAAHAAAPGWGKTAPAERAAILNMIADRIDKNAAALA
Mb0467|M.bovis_AF2122/97 VPRSDAADIDKALDAAHAAAPGWGKTAPAERAAILNMIADRIDKNAAALA
MMAR_0780|M.marinum_M IPRSDEADVEMALDAAHAAAPAWGKMAPAERAAILNKIADRIDENRAALA
MUL_1416|M.ulcerans_Agy99 IPRSDEADVEMALDAAHAAAPAWGKMAPAERAAILNKIADRIDENRAALA
MAV_4691|M.avium_104 VARSDEADVDKALDAAHAAAPAWGKTAPPERAAILNKIADRIEENLESLA
Mflv_4952|M.gilvum_PYR-GCK VARSDEADIEKALDAAHAAAPAWGKTSAAERAVILNKIADRIEENLESIA
Mvan_1468|M.vanbaalenii_PYR-1 VARSDESDIEKALDAAHAAAPAWGKTSAAERAVILNKIADRIEENLESIA
TH_3284|M.thermoresistible__bu VARSTEADIDKALDAAHAAAPAWGKTAPAERALILNRIADRIEANLESIA
MSMEG_0900|M.smegmatis_MC2_155 VARSSSADIEKALDAAHAAAPAWGKTAPAERALILNRIADRMEQNLEALA
MAB_2792c|M.abscessus_ATCC_199 IPRSDEADVEKALDAAHAAAPGWAKLSPADRALILNRVADRMEANLEAIA
MLBr_02573|M.leprae_Br4923 FTPTTQDEVEDAIARAYARFDNYRHTTFTQRAKWANATADLLEAEANQSA
.. : ::: *: *:* : : : .:** * ** :: : *
Rv0458|M.tuberculosis_H37Rv VAEVWDNGKPVREALAADIPLAVDHFRYFAA---AIRAQEGALSQIDEDT
Mb0467|M.bovis_AF2122/97 VAEVWDNGKPVREALAADIPLAVDHFRYFAA---AIRAQEGALSQIDEDT
MMAR_0780|M.marinum_M VAEVWDNGKPVREAIAADIPLAADHFRYFAA---AIRAQEGSLSQIDQDT
MUL_1416|M.ulcerans_Agy99 VAEVWDNGKPVREAIAADIPLAADHFRYFAA---AIRAQEGSLSQIDQDT
MAV_4691|M.avium_104 VAEVWDNGKPIREALAADIPLAADHFRYFAG---ALRAQEGSLSQIDDDT
Mflv_4952|M.gilvum_PYR-GCK LAESWDNGKPIRETLNADLPLAVDHFRYFAG---CIRAQEGSLSEVDADT
Mvan_1468|M.vanbaalenii_PYR-1 LAESWDNGKPIRETLNADIPLAVDHFRYFAG---AIRAQEGSLSEIDDDT
TH_3284|M.thermoresistible__bu LAESWDNGKPIRETLNADIPLAVDHFRYFAG---AIRAQEGSLSQIDDDT
MSMEG_0900|M.smegmatis_MC2_155 LAEAWDNGKPIRETLNADIPLAIDHFRYFAS---AIRAQEGSLSQVDEDT
MAB_2792c|M.abscessus_ATCC_199 VAESWDNGKPIRETVNADVPLAIDHFRYFAG---VLRAQEGSLSQIDEDT
MLBr_02573|M.leprae_Br4923 ALMTLEMGKTLQSAKDEAMKCAKG-FRYYAEKAETLLADEPAEAAAVGAS
: **.::.: : * . ***:* : *:* : : :
Rv0458|M.tuberculosis_H37Rv VAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPAS
Mb0467|M.bovis_AF2122/97 VAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPAS
MMAR_0780|M.marinum_M VAYHFHEPLGVVGQIIPWNFPILMGAWKLAPALAAGNAVVLKPAEQTPAS
MUL_1416|M.ulcerans_Agy99 VAYQFHEPLGVVGQIIPWNFPILMGAWKLAPALAAGNAVVLKPAEQTPAS
MAV_4691|M.avium_104 VAYHFHEPLGVVGQIIPWNFPILMGAWKLAPALAAGNAVVLKPAEQTPVS
Mflv_4952|M.gilvum_PYR-GCK VAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAVVLKPAEQTPAS
Mvan_1468|M.vanbaalenii_PYR-1 VAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAIVLKPAEQTPAS
TH_3284|M.thermoresistible__bu VAYHFHEPLGVVGQIIPWNFPILMATWKLAPALAAGNAVVLKPAEQTPAS
MSMEG_0900|M.smegmatis_MC2_155 VAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAVVLKPAEQTPAS
MAB_2792c|M.abscessus_ATCC_199 VAYHFHEPLGVVGQIIPWNFPLLMASWKLAPALAAGNTVVLKPAEQTPAS
MLBr_02573|M.leprae_Br4923 KALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHASNVPQC
* ::***** ::*****: **** ***. :** *.:.* .
Rv0458|M.tuberculosis_H37Rv VLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFTGETTTGR
Mb0467|M.bovis_AF2122/97 VLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFTGETTTGR
MMAR_0780|M.marinum_M VLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSNRIAKVAFTGETTTGR
MUL_1416|M.ulcerans_Agy99 VLYLMSLIGDLLPPGVVNVVNGFGAEAGRPLASSNRIAKVAFTGETTTGR
MAV_4691|M.avium_104 VLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSNRIAKIAFTGETTTGR
Mflv_4952|M.gilvum_PYR-GCK ILYLMEVIGDLLPAGVVNVVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
Mvan_1468|M.vanbaalenii_PYR-1 ILYLMELIADLLPAGVINVVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
TH_3284|M.thermoresistible__bu VMYLMSLIGDLLPPGVVNVVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
MSMEG_0900|M.smegmatis_MC2_155 VLYLMSLIADLVPAGVVNIVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
MAB_2792c|M.abscessus_ATCC_199 ILHLFSLIGDLLPPGVVNIVNGFGVEAGKPLASSSRIAKIAFTGETSTGR
MLBr_02573|M.leprae_Br4923 ALYLADVIARGGFPEDCFQTLLISANGVEAILRDPRVAAATLTGSEPAGQ
::* .:*. . . :..:. ..: . *:* ::**. .:*:
Rv0458|M.tuberculosis_H37Rv LIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEGFTMFALN
Mb0467|M.bovis_AF2122/97 LIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEGFTMFALN
MMAR_0780|M.marinum_M LIMQYASQNLIPVTLELGGKSPNIFFSDVMAKPDDFQDKALEGFTMFALN
MUL_1416|M.ulcerans_Agy99 LIMQYASQNLIPVTLELGGKSPNIFFSDVMAKPDDFQDKALEGFTMFALN
MAV_4691|M.avium_104 LIMQYASQNLIPVTLELGGKSPNIFFSDVMAKADDYQDKALEGFTMFALN
Mflv_4952|M.gilvum_PYR-GCK LIMQYASQNLIPVTLELGGKSPNIFFNDVLAASDDYQDKALEGFTMFALN
Mvan_1468|M.vanbaalenii_PYR-1 LIMQYASQNLIPVTLELGGKSPNIFFNDVLAQADNYQDKALEGFTMFALN
TH_3284|M.thermoresistible__bu LIMQYASQNLIPVTLELGGKSPNIFFADVMAASDDFCDKALEGFTMFALN
MSMEG_0900|M.smegmatis_MC2_155 LIMQYASQNLIPVTLELGGKSPNIFFSDVMAAADDFQDKALEGFTMFALN
MAB_2792c|M.abscessus_ATCC_199 LIMQYASENLIPVTLELGGKSPNLFFSDVMAGGDDFQDKALEGFTMFAFN
MLBr_02573|M.leprae_Br4923 AVGAIAGNEIKPTVLELGGSDP-----FIVMPSADLDAAVATAVTGRVQN
: *..:: *..*****..* :: : . ..* . *
Rv0458|M.tuberculosis_H37Rv QGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDTETMLGSQASN
Mb0467|M.bovis_AF2122/97 QGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDTETMLGSQASN
MMAR_0780|M.marinum_M QGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLNIETMLGSQASN
MUL_1416|M.ulcerans_Agy99 QGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLNIETMLGSQASN
MAV_4691|M.avium_104 QGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDSETMLGSQASN
Mflv_4952|M.gilvum_PYR-GCK QGEVCTCPSRSLIQADIYDEFLALAAIRTKAVRQGDPLDTETMIGAQASN
Mvan_1468|M.vanbaalenii_PYR-1 QGEVCTCPSRSLIQADIYDEFLALAAIRTKAVRQGDPLDTETMIGAQASN
TH_3284|M.thermoresistible__bu QGEVCTCPSRSLIQADIYDEFLELATIRTKAVRQGDPLDTETMVGAQASN
MSMEG_0900|M.smegmatis_MC2_155 QGEVCTCPSRSLIQSDIFDEFLELAAIRTKAVRQGDPLDTETMIGSQASN
MAB_2792c|M.abscessus_ATCC_199 QGEVCTCPSRSLIQADIFDDFLELAAIRTKAIRQGDPLDTETMMGAQASH
MLBr_02573|M.leprae_Br4923 NGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLATE
:*: * ...* : ::**:*:*: . * :::* *** : :* :*. *:.
Rv0458|M.tuberculosis_H37Rv DQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNM
Mb0467|M.bovis_AF2122/97 DQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNM
MMAR_0780|M.marinum_M DQLEKVLSYIEIGKEEGAKVITGGERAELGGDLSGGFYMQPTIFSGTNKM
MUL_1416|M.ulcerans_Agy99 DQLEKVLSYIEIGKEEGAKVITGGERAELGGDLSGGFYMQPTIFSGTNKM
MAV_4691|M.avium_104 DQLEKVLSYIAIGKDEGATIITGGERAELGGDLSGGFYMQPTIFAGNNKM
Mflv_4952|M.gilvum_PYR-GCK DQLEKILSYIEIGKSEGAKVVTGGERAELGGDLNGGYYVAPTIFTGNNTM
Mvan_1468|M.vanbaalenii_PYR-1 DQLEKILSYIEIGKSEGAQVVTGGERAELGGDLNGGYYVAPTIFTGHNKM
TH_3284|M.thermoresistible__bu DQLEKILSYIDIGRSEGATVVTGGERAELGGDLSGGYYVQPTIFTGDNSM
MSMEG_0900|M.smegmatis_MC2_155 DQFEKILSYIEIGKSEGARIVTGGERADLGGDLSGGYYIQPTIFTGHNKM
MAB_2792c|M.abscessus_ATCC_199 EQLEKILSYIDIGKSEGARLVTGGDRADLGGDLSGGYYVTPTVFAGDNSM
MLBr_02573|M.leprae_Br4923 SGRAQVEQQVDAAAAAGAVIRCGGKRPDR----PGWFYPPTVITDITKDM
. :: . : . ** : **.*.: * :* ..: : *
Rv0458|M.tuberculosis_H37Rv RIFKEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDGNTAYRAG
Mb0467|M.bovis_AF2122/97 RIFKEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDGNTAYRAG
MMAR_0780|M.marinum_M RIFQEEIFGPVVAVTPFTDYDDAMGIANDTLYGLGAGVWSRDGNTAYRAG
MUL_1416|M.ulcerans_Agy99 RIFQEEIFGPVVAVTPFTDYDDAMGIANDTLYGLGAGVWSRDGNTAYRAG
MAV_4691|M.avium_104 RIFQEEIFGPVVAVTSFTDYDDAISIANDTLYGLGAGVWSRDGNTAYRAG
Mflv_4952|M.gilvum_PYR-GCK RIFQEEIFGPVVAVTSFTDYDDAISLANDTLYGLGAGVWSRNGNTAYRAG
Mvan_1468|M.vanbaalenii_PYR-1 RIFQEEIFGPVVAVTSFTDYDDAISIANDTLYGLGAGVWSRDGNTAYRAG
TH_3284|M.thermoresistible__bu RIFQEEIFGPVVAVTSFTDYDDAIRIANDTLYGLGAGVWSRDGNTAYRAG
MSMEG_0900|M.smegmatis_MC2_155 RIFQEEIFGPVVAVTSFSDYDDAISIANDTLYGLGAGVWSRDGNTAYRAG
MAB_2792c|M.abscessus_ATCC_199 RIFQEEIFGPVLAVTSFADYDDAIAIANDTPYGLGAGVWSRNGNIAYRAG
MLBr_02573|M.leprae_Br4923 ALYTDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFI
:: :*:**** :* :: ***: :** * :***:..*::: . :
Rv0458|M.tuberculosis_H37Rv RDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGREGHQMMLQHYQHTKNLLV
Mb0467|M.bovis_AF2122/97 RDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGREGHQMMLQHYQHTKNLLV
MMAR_0780|M.marinum_M RDIQAGRVWVNCYHVYPAHSAFGGYKQSGIGREGHQMMLGHYQQTKNLLV
MUL_1416|M.ulcerans_Agy99 RDIQAGRVWVNCYHVYPAHSAFGGYKQSGIGREGHQKMLGHYQQTKNLLV
MAV_4691|M.avium_104 RDIQAGRVWVNCYHAYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNMLV
Mflv_4952|M.gilvum_PYR-GCK RDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRENHRMMLDHYQQTKNLLV
Mvan_1468|M.vanbaalenii_PYR-1 RDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNLLV
TH_3284|M.thermoresistible__bu RDIKAGRVWTNCYHVYPAHAAFGGYKQSGIGRENHTMMLDHYQQTKNLLV
MSMEG_0900|M.smegmatis_MC2_155 RDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNLLV
MAB_2792c|M.abscessus_ATCC_199 RDIKAGRVWTNCYHQYPAHAAFGGYKRSGIGRENHKMMLDHYQQTKNLLV
MLBr_02573|M.leprae_Br4923 DNIVAGQVFINGMTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTVWI
:* **:*: * .. .*** *:** *** : .: : *.: :
Rv0458|M.tuberculosis_H37Rv SYSDKALGFF
Mb0467|M.bovis_AF2122/97 SYSDKALGFF
MMAR_0780|M.marinum_M SYSDKALGLF
MUL_1416|M.ulcerans_Agy99 SYSDKPLGLF
MAV_4691|M.avium_104 SYSNKAQGFF
Mflv_4952|M.gilvum_PYR-GCK SYSDQALGFF
Mvan_1468|M.vanbaalenii_PYR-1 SYSDKALGFF
TH_3284|M.thermoresistible__bu SYSTKAQGFF
MSMEG_0900|M.smegmatis_MC2_155 SYSDKAQGFF
MAB_2792c|M.abscessus_ATCC_199 SYGSKAQGFF
MLBr_02573|M.leprae_Br4923 A---------
: