For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTVYARPGADGSLMSFKPRYDNFIGGQWVAPNAGRYFENPSPVTGQPFTEVARSDESDIEKALDAAHAAA PAWGKTSAAERAVILNKIADRIEENLESIALAESWDNGKPIRETLNADIPLAVDHFRYFAGAIRAQEGSL SEIDDDTVAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAIVLKPAEQTPASILYLMELIADLLP AGVINVVNGFGVEAGKPLASSNRIAKIAFTGETTTGRLIMQYASQNLIPVTLELGGKSPNIFFNDVLAQA DNYQDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLALAAIRTKAVRQGDPLDTETMIGAQASNDQL EKILSYIEIGKSEGAQVVTGGERAELGGDLNGGYYVAPTIFTGHNKMRIFQEEIFGPVVAVTSFTDYDDA ISIANDTLYGLGAGVWSRDGNTAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRENHKMMLDHYQ QTKNLLVSYSDKALGFF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1468 | - | - | 100% (507) | aldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0014 | - | 1e-87 | 39.64% (497) | betaine-aldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0352 | - | 2e-85 | 39.75% (488) | aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0467 | - | 0.0 | 84.62% (507) | aldehyde dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4952 | - | 0.0 | 96.06% (507) | aldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv0458 | - | 0.0 | 84.62% (507) | aldehyde dehydrogenase |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 3e-51 | 31.10% (447) | succinic semialdehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2792c | - | 0.0 | 82.84% (507) | aldehyde dehydrogenase |
| M. marinum M | MMAR_4912 | - | 0.0 | 88.36% (507) | aldehyde dehydrogenase |
| M. avium 104 | MAV_4691 | - | 0.0 | 87.57% (507) | eptc-inducible aldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_1543 | - | 0.0 | 90.73% (507) | eptc-inducible aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3284 | - | 0.0 | 90.69% (494) | PUTATIVE eptc-inducible aldehyde dehydrogenase |
| M. ulcerans Agy99 | MUL_0494 | - | 0.0 | 87.97% (507) | aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0467|M.bovis_AF2122/97 -------MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPV
Rv0458|M.tuberculosis_H37Rv -------MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPV
MAV_4691|M.avium_104 -------MTVFARPGSAGALMSYESRYDNFIGGQWVAPARGRYFENPTPV
Mvan_1468|M.vanbaalenii_PYR-1 -------MTVYARPGADGSLMSFKPRYDNFIGGQWVAPNAGRYFENPSPV
Mflv_4952|M.gilvum_PYR-GCK -------MTVYARPGADGSLMSFKPRYDNFIGGQWVAPTAGRYFENPSPV
MSMEG_1543|M.smegmatis_MC2_155 MSEQEKAMTVYARPGADGAKMSFQARYDNYIGGEWVAPVEGRYFENPTPV
TH_3284|M.thermoresistible__bu --------------------MSFESRYDNFIGGEWVAPVGGEYFENPSPV
MMAR_4912|M.marinum_M -------MTVFARPGAHSSLMTFESRYGNFIGGEWVAPAAGEYFEDLTPV
MUL_0494|M.ulcerans_Agy99 -------MTVFARPGVHSSLMTFESRYDNFIGGEWVAPAAGEYFEDLTPV
MAB_2792c|M.abscessus_ATCC_199 -------MTVYARPGAQGSLMTFASRYENFIGGQWVPPEHGRYFENRTPV
MLBr_02573|M.leprae_Br4923 -----------------------------------------MSIATINPA
: .*.
Mb0467|M.bovis_AF2122/97 TGQPFCEVPRSDAADIDKALDAAHAAAPGWGKTAPAERAAILNMIADRID
Rv0458|M.tuberculosis_H37Rv TGQPFCEVPRSDAADIDKALDAAHAAAPGWGKTAPAERAAILNMIADRID
MAV_4691|M.avium_104 TGQTFCEVARSDEADVDKALDAAHAAAPAWGKTAPPERAAILNKIADRIE
Mvan_1468|M.vanbaalenii_PYR-1 TGQPFTEVARSDESDIEKALDAAHAAAPAWGKTSAAERAVILNKIADRIE
Mflv_4952|M.gilvum_PYR-GCK TGQPFTEVARSDEADIEKALDAAHAAAPAWGKTSAAERAVILNKIADRIE
MSMEG_1543|M.smegmatis_MC2_155 TGQVFCEVARSSEADIDKALDAAHAAAPAWGKTAPAERALILNRIADRME
TH_3284|M.thermoresistible__bu TGQPFCEVARSTEADIDKALDAAHAAAPAWGKTAPAERALILNRIADRIE
MMAR_4912|M.marinum_M TGAPFCEVPRSTDVDVEKALDAAHAAAPAWGKAAPAERAAILHKIADRME
MUL_0494|M.ulcerans_Agy99 TGAPFCEVPRSTDVDVEKALDAAHAAAPAWGKAAPAERATILHKIADRME
MAB_2792c|M.abscessus_ATCC_199 TGEVFCEIPRSDEADVEKALDAAHAAAPGWAKLSPADRALILNRVADRME
MLBr_02573|M.leprae_Br4923 TGETVKTFTPTTQDEVEDAIARAYARFDNYRHTTFTQRAKWANATADLLE
** . .. : :::.*: *:* : : : .:** : ** ::
Mb0467|M.bovis_AF2122/97 KNAAALAVAEVWDNGKPVREALAADIPLAVDHFRYFAA---AIRAQEGAL
Rv0458|M.tuberculosis_H37Rv KNAAALAVAEVWDNGKPVREALAADIPLAVDHFRYFAA---AIRAQEGAL
MAV_4691|M.avium_104 ENLESLAVAEVWDNGKPIREALAADIPLAADHFRYFAG---ALRAQEGSL
Mvan_1468|M.vanbaalenii_PYR-1 ENLESIALAESWDNGKPIRETLNADIPLAVDHFRYFAG---AIRAQEGSL
Mflv_4952|M.gilvum_PYR-GCK ENLESIALAESWDNGKPIRETLNADLPLAVDHFRYFAG---CIRAQEGSL
MSMEG_1543|M.smegmatis_MC2_155 ENLESIALAESWDNGKPIRETLNADIPLAIDHFRYFAG---VLRAQEGSL
TH_3284|M.thermoresistible__bu ANLESIALAESWDNGKPIRETLNADIPLAVDHFRYFAG---AIRAQEGSL
MMAR_4912|M.marinum_M ANLEALALAESWDNGKPIRETLNADIPLAIDHFRYFAG---AIRAQEGSL
MUL_0494|M.ulcerans_Agy99 ANLEALALAESWDNGKPIREALNADIPLAIDHFRYFAG---AIRAQEGSL
MAB_2792c|M.abscessus_ATCC_199 ANLEAIAVAESWDNGKPIRETVNADVPLAIDHFRYFAG---VLRAQEGSL
MLBr_02573|M.leprae_Br4923 AEANQSAALMTLEMGKTLQSAKDEAMKCAKG-FRYYAEKAETLLADEPAE
: * : **.::.: : * . ***:* : *:* :
Mb0467|M.bovis_AF2122/97 SQIDEDTVAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKP
Rv0458|M.tuberculosis_H37Rv SQIDEDTVAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKP
MAV_4691|M.avium_104 SQIDDDTVAYHFHEPLGVVGQIIPWNFPILMGAWKLAPALAAGNAVVLKP
Mvan_1468|M.vanbaalenii_PYR-1 SEIDDDTVAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAIVLKP
Mflv_4952|M.gilvum_PYR-GCK SEVDADTVAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAVVLKP
MSMEG_1543|M.smegmatis_MC2_155 SQIDEDTVAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAVVLKP
TH_3284|M.thermoresistible__bu SQIDDDTVAYHFHEPLGVVGQIIPWNFPILMATWKLAPALAAGNAVVLKP
MMAR_4912|M.marinum_M SQIDSDTVAYHFHEPLGVVGQIIPWNFPLLMATWKLAPALAAGNAVVLKP
MUL_0494|M.ulcerans_Agy99 SQIDSDTVAYHFHEPLGVVGQIIPWNFPLLMATWKLAPALAAGNAVVLKP
MAB_2792c|M.abscessus_ATCC_199 SQIDEDTVAYHFHEPLGVVGQIIPWNFPLLMASWKLAPALAAGNTVVLKP
MLBr_02573|M.leprae_Br4923 AAAVGASKALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKH
: : * ::***** ::*****: **** ***. :**
Mb0467|M.bovis_AF2122/97 AEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFT
Rv0458|M.tuberculosis_H37Rv AEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFT
MAV_4691|M.avium_104 AEQTPVSVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSNRIAKIAFT
Mvan_1468|M.vanbaalenii_PYR-1 AEQTPASILYLMELIADLLPAGVINVVNGFGVEAGKPLASSNRIAKIAFT
Mflv_4952|M.gilvum_PYR-GCK AEQTPASILYLMEVIGDLLPAGVVNVVNGFGVEAGKPLASSNRIAKIAFT
MSMEG_1543|M.smegmatis_MC2_155 AEQTPVSVLYLFSLIGDLLPAGVVNIVNGFGVEAGKPLASSNRIAKIAFT
TH_3284|M.thermoresistible__bu AEQTPASVMYLMSLIGDLLPPGVVNVVNGFGVEAGKPLASSNRIAKIAFT
MMAR_4912|M.marinum_M AEQTPASILYLMSLIGDLLPAGVVNVVNGFGVEAGKPLASSNRIAKIAFT
MUL_0494|M.ulcerans_Agy99 AEQTPASILYLMSLIGDLLPAGVVNVVNGFGVEAGKPLASSNRIAKIAFT
MAB_2792c|M.abscessus_ATCC_199 AEQTPASILHLFSLIGDLLPPGVVNIVNGFGVEAGKPLASSSRIAKIAFT
MLBr_02573|M.leprae_Br4923 ASNVPQCALYLADVIARGGFPEDCFQTLLISANGVEAILRDPRVAAATLT
*.:.* . ::* .:*. . . :..:. :.: . *:* ::*
Mb0467|M.bovis_AF2122/97 GETTTGRLIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEG
Rv0458|M.tuberculosis_H37Rv GETTTGRLIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEG
MAV_4691|M.avium_104 GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFSDVMAKADDYQDKALEG
Mvan_1468|M.vanbaalenii_PYR-1 GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFNDVLAQADNYQDKALEG
Mflv_4952|M.gilvum_PYR-GCK GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFNDVLAASDDYQDKALEG
MSMEG_1543|M.smegmatis_MC2_155 GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFNNVLAQADDYQDKALEG
TH_3284|M.thermoresistible__bu GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFADVMAASDDFCDKALEG
MMAR_4912|M.marinum_M GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFSDVLAAHDDYQDKALEG
MUL_0494|M.ulcerans_Agy99 GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFPDVLAAHDDYQDKALEG
MAB_2792c|M.abscessus_ATCC_199 GETSTGRLIMQYASENLIPVTLELGGKSPNLFFSDVMAGGDDFQDKALEG
MLBr_02573|M.leprae_Br4923 GSEPAGQAVGAIAGNEIKPTVLELGGSDP-----FIVMPSADLDAAVATA
*. .:*: : *..:: *..*****..* :: : . .
Mb0467|M.bovis_AF2122/97 FTMFALNQGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDTETM
Rv0458|M.tuberculosis_H37Rv FTMFALNQGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDTETM
MAV_4691|M.avium_104 FTMFALNQGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDSETM
Mvan_1468|M.vanbaalenii_PYR-1 FTMFALNQGEVCTCPSRSLIQADIYDEFLALAAIRTKAVRQGDPLDTETM
Mflv_4952|M.gilvum_PYR-GCK FTMFALNQGEVCTCPSRSLIQADIYDEFLALAAIRTKAVRQGDPLDTETM
MSMEG_1543|M.smegmatis_MC2_155 FTMFALNQGEVCTCPSRSLIQSDIFDEFLELAAIRTKAVRQGDPLDTETM
TH_3284|M.thermoresistible__bu FTMFALNQGEVCTCPSRSLIQADIYDEFLELATIRTKAVRQGDPLDTETM
MMAR_4912|M.marinum_M FTMFALNQGEVCTCPSRGLIQADIYDRFLELAAIRTKAVRQGDPLDTETM
MUL_0494|M.ulcerans_Agy99 FTMFALNQGEVCTCPSRGLIQADIYDRFLELAAIRTKAVRQGDPLDTETM
MAB_2792c|M.abscessus_ATCC_199 FTMFAFNQGEVCTCPSRSLIQADIFDDFLELAAIRTKAIRQGDPLDTETM
MLBr_02573|M.leprae_Br4923 VTGRVQNNGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTD
.* . *:*: * ...* : ::**:* *: . * :::* *** *.:*
Mb0467|M.bovis_AF2122/97 LGSQASNDQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTI
Rv0458|M.tuberculosis_H37Rv LGSQASNDQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTI
MAV_4691|M.avium_104 LGSQASNDQLEKVLSYIAIGKDEGATIITGGERAELGGDLSGGFYMQPTI
Mvan_1468|M.vanbaalenii_PYR-1 IGAQASNDQLEKILSYIEIGKSEGAQVVTGGERAELGGDLNGGYYVAPTI
Mflv_4952|M.gilvum_PYR-GCK IGAQASNDQLEKILSYIEIGKSEGAKVVTGGERAELGGDLNGGYYVAPTI
MSMEG_1543|M.smegmatis_MC2_155 IGAQASNDQLEKILSYIEIGKSEGAKLITGGERAQLGGDLNGGYYVAPTI
TH_3284|M.thermoresistible__bu VGAQASNDQLEKILSYIDIGRSEGATVVTGGERAELGGDLSGGYYVQPTI
MMAR_4912|M.marinum_M IGAQASNDQLQKILSYIEIGKEEGARVVTGGERCELGGDLNGGYYVQPTI
MUL_0494|M.ulcerans_Agy99 IGAQASNDQLQKILSYIEIGKEEGARVVTGGERCELGGDLNGGYYVQPTI
MAB_2792c|M.abscessus_ATCC_199 MGAQASHEQLEKILSYIDIGKSEGARLVTGGDRADLGGDLSGGYYVTPTV
MLBr_02573|M.leprae_Br4923 VGPLATESGRAQVEQQVDAAAAAGAVIRCGGKRPDR----PGWFYPPTVI
:*. *:.. :: . : . ** : **.* : * :* ..:
Mb0467|M.bovis_AF2122/97 FTGTNNMRIFKEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDG
Rv0458|M.tuberculosis_H37Rv FTGTNNMRIFKEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDG
MAV_4691|M.avium_104 FAGNNKMRIFQEEIFGPVVAVTSFTDYDDAISIANDTLYGLGAGVWSRDG
Mvan_1468|M.vanbaalenii_PYR-1 FTGHNKMRIFQEEIFGPVVAVTSFTDYDDAISIANDTLYGLGAGVWSRDG
Mflv_4952|M.gilvum_PYR-GCK FTGNNTMRIFQEEIFGPVVAVTSFTDYDDAISLANDTLYGLGAGVWSRNG
MSMEG_1543|M.smegmatis_MC2_155 FTGNNKMRIFQEEIFGPVVAVTSFSDYDDAISIANDTLYGLGAGVWSRDG
TH_3284|M.thermoresistible__bu FTGDNSMRIFQEEIFGPVVAVTSFTDYDDAIRIANDTLYGLGAGVWSRDG
MMAR_4912|M.marinum_M FEGTNNMRIFQEEIFGPVVSVTSFTDYDDAIRIANDTLYGLGAGVWSRDG
MUL_0494|M.ulcerans_Agy99 FEGTNNMRIFQEEIFGPVVSVTLFTDYDDAIRIANDTLYGLGAGVWSRDG
MAB_2792c|M.abscessus_ATCC_199 FAGDNSMRIFQEEIFGPVLAVTSFADYDDAIAIANDTPYGLGAGVWSRNG
MLBr_02573|M.leprae_Br4923 TDITKDMALYTDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNE
: * :: :*:**** :* :: **** :** * :***:..*:::
Mb0467|M.bovis_AF2122/97 NTAYRAGRDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGREGHQMMLQHYQ
Rv0458|M.tuberculosis_H37Rv NTAYRAGRDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGREGHQMMLQHYQ
MAV_4691|M.avium_104 NTAYRAGRDIQAGRVWVNCYHAYPAHAAFGGYKQSGIGRENHKMMLDHYQ
Mvan_1468|M.vanbaalenii_PYR-1 NTAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRENHKMMLDHYQ
Mflv_4952|M.gilvum_PYR-GCK NTAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRENHRMMLDHYQ
MSMEG_1543|M.smegmatis_MC2_155 NIAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRETHKMMLDHYQ
TH_3284|M.thermoresistible__bu NTAYRAGRDIKAGRVWTNCYHVYPAHAAFGGYKQSGIGRENHTMMLDHYQ
MMAR_4912|M.marinum_M NTAYRAGRDIKAGRVWTNCYHAYPAHAAFGGYKQSGIGRENHKMMLDHYQ
MUL_0494|M.ulcerans_Agy99 NTAYRAGRDIKAGRVWTNCYHAYPAHAAFGGYKQSGIGRENHKMMLDHYQ
MAB_2792c|M.abscessus_ATCC_199 NIAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYKRSGIGRENHKMMLDHYQ
MLBr_02573|M.leprae_Br4923 SEQRHFIDNIVAGQVFINGMTVSYPELPFGGIKRSGYGRELSTHGIREFC
. : :* **:*: * .. .*** *:** *** : .:
Mb0467|M.bovis_AF2122/97 HTKNLLVSYSDKALGFF
Rv0458|M.tuberculosis_H37Rv HTKNLLVSYSDKALGFF
MAV_4691|M.avium_104 QTKNMLVSYSNKAQGFF
Mvan_1468|M.vanbaalenii_PYR-1 QTKNLLVSYSDKALGFF
Mflv_4952|M.gilvum_PYR-GCK QTKNLLVSYSDQALGFF
MSMEG_1543|M.smegmatis_MC2_155 QTKNLLVSYSNKAQGFF
TH_3284|M.thermoresistible__bu QTKNLLVSYSTKAQGFF
MMAR_4912|M.marinum_M QTKNLLVSYGSKAQGFF
MUL_0494|M.ulcerans_Agy99 QTKNLLVSYGSKAQGFF
MAB_2792c|M.abscessus_ATCC_199 QTKNLLVSYGSKAQGFF
MLBr_02573|M.leprae_Br4923 NIKTVWIA---------
: *.: ::