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TVFARPGSAGALMSYESRYDNFIGGQWVAPARGRYFENPTPVTGQTFCEVARSDEADVDKALDAAHAAAP AWGKTAPPERAAILNKIADRIEENLESLAVAEVWDNGKPIREALAADIPLAADHFRYFAGALRAQEGSLS QIDDDTVAYHFHEPLGVVGQIIPWNFPILMGAWKLAPALAAGNAVVLKPAEQTPVSVLYLMSLIGDLLPP GVVNVVNGFGAEAGKPLASSNRIAKIAFTGETTTGRLIMQYASQNLIPVTLELGGKSPNIFFSDVMAKAD DYQDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDSETMLGSQASNDQLE KVLSYIAIGKDEGATIITGGERAELGGDLSGGFYMQPTIFAGNNKMRIFQEEIFGPVVAVTSFTDYDDAI SIANDTLYGLGAGVWSRDGNTAYRAGRDIQAGRVWVNCYHAYPAHAAFGGYKQSGIGRENHKMMLDHYQQ TKNMLVSYSNKAQGFF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4691 | - | - | 100% (507) | eptc-inducible aldehyde dehydrogenase |
| M. avium 104 | MAV_1897 | - | 6e-93 | 40.24% (492) | betaine-aldehyde dehydrogenase |
| M. avium 104 | MAV_2608 | - | 5e-90 | 38.74% (493) | aldehyde dehydrogenase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0467 | - | 0.0 | 89.35% (507) | aldehyde dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4952 | - | 0.0 | 86.59% (507) | aldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv0458 | - | 0.0 | 89.35% (507) | aldehyde dehydrogenase |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 5e-50 | 32.28% (443) | succinic semialdehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2792c | - | 0.0 | 81.85% (507) | aldehyde dehydrogenase |
| M. marinum M | MMAR_0780 | putA_1 | 0.0 | 91.12% (507) | aldehyde dehydrogenase, PutA_1 |
| M. smegmatis MC2 155 | MSMEG_1543 | - | 0.0 | 88.36% (507) | eptc-inducible aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3284 | - | 0.0 | 89.47% (494) | PUTATIVE eptc-inducible aldehyde dehydrogenase |
| M. ulcerans Agy99 | MUL_1416 | - | 0.0 | 90.14% (507) | aldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1468 | - | 0.0 | 87.57% (507) | aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0467|M.bovis_AF2122/97 -------MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPV
Rv0458|M.tuberculosis_H37Rv -------MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPV
MMAR_0780|M.marinum_M -------MTVFARPGSAGALMSFESRYGNFIGGEWVAPARGRYFEDLTPV
MUL_1416|M.ulcerans_Agy99 -------MTVFARPGSAGALMSFESRYGNLIGGEWVAPARGRYFEDLTPV
MAV_4691|M.avium_104 -------MTVFARPGSAGALMSYESRYDNFIGGQWVAPARGRYFENPTPV
Mflv_4952|M.gilvum_PYR-GCK -------MTVYARPGADGSLMSFKPRYDNFIGGQWVAPTAGRYFENPSPV
Mvan_1468|M.vanbaalenii_PYR-1 -------MTVYARPGADGSLMSFKPRYDNFIGGQWVAPNAGRYFENPSPV
MSMEG_1543|M.smegmatis_MC2_155 MSEQEKAMTVYARPGADGAKMSFQARYDNYIGGEWVAPVEGRYFENPTPV
TH_3284|M.thermoresistible__bu --------------------MSFESRYDNFIGGEWVAPVGGEYFENPSPV
MAB_2792c|M.abscessus_ATCC_199 -------MTVYARPGAQGSLMTFASRYENFIGGQWVPPEHGRYFENRTPV
MLBr_02573|M.leprae_Br4923 -----------------------------------------MSIATINPA
: .*.
Mb0467|M.bovis_AF2122/97 TGQPFCEVPRSDAADIDKALDAAHAAAPGWGKTAPAERAAILNMIADRID
Rv0458|M.tuberculosis_H37Rv TGQPFCEVPRSDAADIDKALDAAHAAAPGWGKTAPAERAAILNMIADRID
MMAR_0780|M.marinum_M TGQPFCEIPRSDEADVEMALDAAHAAAPAWGKMAPAERAAILNKIADRID
MUL_1416|M.ulcerans_Agy99 TGQPFCEIPRSDEADVEMALDAAHAAAPAWGKMAPAERAAILNKIADRID
MAV_4691|M.avium_104 TGQTFCEVARSDEADVDKALDAAHAAAPAWGKTAPPERAAILNKIADRIE
Mflv_4952|M.gilvum_PYR-GCK TGQPFTEVARSDEADIEKALDAAHAAAPAWGKTSAAERAVILNKIADRIE
Mvan_1468|M.vanbaalenii_PYR-1 TGQPFTEVARSDESDIEKALDAAHAAAPAWGKTSAAERAVILNKIADRIE
MSMEG_1543|M.smegmatis_MC2_155 TGQVFCEVARSSEADIDKALDAAHAAAPAWGKTAPAERALILNRIADRME
TH_3284|M.thermoresistible__bu TGQPFCEVARSTEADIDKALDAAHAAAPAWGKTAPAERALILNRIADRIE
MAB_2792c|M.abscessus_ATCC_199 TGEVFCEIPRSDEADVEKALDAAHAAAPGWAKLSPADRALILNRVADRME
MLBr_02573|M.leprae_Br4923 TGETVKTFTPTTQDEVEDAIARAYARFDNYRHTTFTQRAKWANATADLLE
**: . .. : ::: *: *:* : : : .:** * ** ::
Mb0467|M.bovis_AF2122/97 KNAAALAVAEVWDNGKPVREALAADIPLAVDHFRYFAA---AIRAQEGAL
Rv0458|M.tuberculosis_H37Rv KNAAALAVAEVWDNGKPVREALAADIPLAVDHFRYFAA---AIRAQEGAL
MMAR_0780|M.marinum_M ENRAALAVAEVWDNGKPVREAIAADIPLAADHFRYFAA---AIRAQEGSL
MUL_1416|M.ulcerans_Agy99 ENRAALAVAEVWDNGKPVREAIAADIPLAADHFRYFAA---AIRAQEGSL
MAV_4691|M.avium_104 ENLESLAVAEVWDNGKPIREALAADIPLAADHFRYFAG---ALRAQEGSL
Mflv_4952|M.gilvum_PYR-GCK ENLESIALAESWDNGKPIRETLNADLPLAVDHFRYFAG---CIRAQEGSL
Mvan_1468|M.vanbaalenii_PYR-1 ENLESIALAESWDNGKPIRETLNADIPLAVDHFRYFAG---AIRAQEGSL
MSMEG_1543|M.smegmatis_MC2_155 ENLESIALAESWDNGKPIRETLNADIPLAIDHFRYFAG---VLRAQEGSL
TH_3284|M.thermoresistible__bu ANLESIALAESWDNGKPIRETLNADIPLAVDHFRYFAG---AIRAQEGSL
MAB_2792c|M.abscessus_ATCC_199 ANLEAIAVAESWDNGKPIRETVNADVPLAIDHFRYFAG---VLRAQEGSL
MLBr_02573|M.leprae_Br4923 AEANQSAALMTLEMGKTLQSAKDEAMKCAKG-FRYYAEKAETLLADEPAE
: * : **.::.: : * . ***:* : *:* :
Mb0467|M.bovis_AF2122/97 SQIDEDTVAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKP
Rv0458|M.tuberculosis_H37Rv SQIDEDTVAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKP
MMAR_0780|M.marinum_M SQIDQDTVAYHFHEPLGVVGQIIPWNFPILMGAWKLAPALAAGNAVVLKP
MUL_1416|M.ulcerans_Agy99 SQIDQDTVAYQFHEPLGVVGQIIPWNFPILMGAWKLAPALAAGNAVVLKP
MAV_4691|M.avium_104 SQIDDDTVAYHFHEPLGVVGQIIPWNFPILMGAWKLAPALAAGNAVVLKP
Mflv_4952|M.gilvum_PYR-GCK SEVDADTVAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAVVLKP
Mvan_1468|M.vanbaalenii_PYR-1 SEIDDDTVAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAIVLKP
MSMEG_1543|M.smegmatis_MC2_155 SQIDEDTVAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAVVLKP
TH_3284|M.thermoresistible__bu SQIDDDTVAYHFHEPLGVVGQIIPWNFPILMATWKLAPALAAGNAVVLKP
MAB_2792c|M.abscessus_ATCC_199 SQIDEDTVAYHFHEPLGVVGQIIPWNFPLLMASWKLAPALAAGNTVVLKP
MLBr_02573|M.leprae_Br4923 AAAVGASKALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKH
: : * ::***** ::*****: **** ***. :**
Mb0467|M.bovis_AF2122/97 AEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFT
Rv0458|M.tuberculosis_H37Rv AEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFT
MMAR_0780|M.marinum_M AEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSNRIAKVAFT
MUL_1416|M.ulcerans_Agy99 AEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGRPLASSNRIAKVAFT
MAV_4691|M.avium_104 AEQTPVSVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSNRIAKIAFT
Mflv_4952|M.gilvum_PYR-GCK AEQTPASILYLMEVIGDLLPAGVVNVVNGFGVEAGKPLASSNRIAKIAFT
Mvan_1468|M.vanbaalenii_PYR-1 AEQTPASILYLMELIADLLPAGVINVVNGFGVEAGKPLASSNRIAKIAFT
MSMEG_1543|M.smegmatis_MC2_155 AEQTPVSVLYLFSLIGDLLPAGVVNIVNGFGVEAGKPLASSNRIAKIAFT
TH_3284|M.thermoresistible__bu AEQTPASVMYLMSLIGDLLPPGVVNVVNGFGVEAGKPLASSNRIAKIAFT
MAB_2792c|M.abscessus_ATCC_199 AEQTPASILHLFSLIGDLLPPGVVNIVNGFGVEAGKPLASSSRIAKIAFT
MLBr_02573|M.leprae_Br4923 ASNVPQCALYLADVIARGGFPEDCFQTLLISANGVEAILRDPRVAAATLT
*.:.* . ::* .:*. . . :..:. ..: . *:* ::*
Mb0467|M.bovis_AF2122/97 GETTTGRLIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEG
Rv0458|M.tuberculosis_H37Rv GETTTGRLIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEG
MMAR_0780|M.marinum_M GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFSDVMAKPDDFQDKALEG
MUL_1416|M.ulcerans_Agy99 GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFSDVMAKPDDFQDKALEG
MAV_4691|M.avium_104 GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFSDVMAKADDYQDKALEG
Mflv_4952|M.gilvum_PYR-GCK GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFNDVLAASDDYQDKALEG
Mvan_1468|M.vanbaalenii_PYR-1 GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFNDVLAQADNYQDKALEG
MSMEG_1543|M.smegmatis_MC2_155 GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFNNVLAQADDYQDKALEG
TH_3284|M.thermoresistible__bu GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFADVMAASDDFCDKALEG
MAB_2792c|M.abscessus_ATCC_199 GETSTGRLIMQYASENLIPVTLELGGKSPNLFFSDVMAGGDDFQDKALEG
MLBr_02573|M.leprae_Br4923 GSEPAGQAVGAIAGNEIKPTVLELGGSDP-----FIVMPSADLDAAVATA
*. .:*: : *..:: *..*****..* :: : . .
Mb0467|M.bovis_AF2122/97 FTMFALNQGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDTETM
Rv0458|M.tuberculosis_H37Rv FTMFALNQGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDTETM
MMAR_0780|M.marinum_M FTMFALNQGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLNIETM
MUL_1416|M.ulcerans_Agy99 FTMFALNQGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLNIETM
MAV_4691|M.avium_104 FTMFALNQGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDSETM
Mflv_4952|M.gilvum_PYR-GCK FTMFALNQGEVCTCPSRSLIQADIYDEFLALAAIRTKAVRQGDPLDTETM
Mvan_1468|M.vanbaalenii_PYR-1 FTMFALNQGEVCTCPSRSLIQADIYDEFLALAAIRTKAVRQGDPLDTETM
MSMEG_1543|M.smegmatis_MC2_155 FTMFALNQGEVCTCPSRSLIQSDIFDEFLELAAIRTKAVRQGDPLDTETM
TH_3284|M.thermoresistible__bu FTMFALNQGEVCTCPSRSLIQADIYDEFLELATIRTKAVRQGDPLDTETM
MAB_2792c|M.abscessus_ATCC_199 FTMFAFNQGEVCTCPSRSLIQADIFDDFLELAAIRTKAIRQGDPLDTETM
MLBr_02573|M.leprae_Br4923 VTGRVQNNGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTD
.* . *:*: * ...* : ::**:*:*: . * :::* *** : :*
Mb0467|M.bovis_AF2122/97 LGSQASNDQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTI
Rv0458|M.tuberculosis_H37Rv LGSQASNDQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTI
MMAR_0780|M.marinum_M LGSQASNDQLEKVLSYIEIGKEEGAKVITGGERAELGGDLSGGFYMQPTI
MUL_1416|M.ulcerans_Agy99 LGSQASNDQLEKVLSYIEIGKEEGAKVITGGERAELGGDLSGGFYMQPTI
MAV_4691|M.avium_104 LGSQASNDQLEKVLSYIAIGKDEGATIITGGERAELGGDLSGGFYMQPTI
Mflv_4952|M.gilvum_PYR-GCK IGAQASNDQLEKILSYIEIGKSEGAKVVTGGERAELGGDLNGGYYVAPTI
Mvan_1468|M.vanbaalenii_PYR-1 IGAQASNDQLEKILSYIEIGKSEGAQVVTGGERAELGGDLNGGYYVAPTI
MSMEG_1543|M.smegmatis_MC2_155 IGAQASNDQLEKILSYIEIGKSEGAKLITGGERAQLGGDLNGGYYVAPTI
TH_3284|M.thermoresistible__bu VGAQASNDQLEKILSYIDIGRSEGATVVTGGERAELGGDLSGGYYVQPTI
MAB_2792c|M.abscessus_ATCC_199 MGAQASHEQLEKILSYIDIGKSEGARLVTGGDRADLGGDLSGGYYVTPTV
MLBr_02573|M.leprae_Br4923 VGPLATESGRAQVEQQVDAAAAAGAVIRCGGKRPDR----PGWFYPPTVI
:*. *:.. :: . : . ** : **.*.: * :* ..:
Mb0467|M.bovis_AF2122/97 FTGTNNMRIFKEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDG
Rv0458|M.tuberculosis_H37Rv FTGTNNMRIFKEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDG
MMAR_0780|M.marinum_M FSGTNKMRIFQEEIFGPVVAVTPFTDYDDAMGIANDTLYGLGAGVWSRDG
MUL_1416|M.ulcerans_Agy99 FSGTNKMRIFQEEIFGPVVAVTPFTDYDDAMGIANDTLYGLGAGVWSRDG
MAV_4691|M.avium_104 FAGNNKMRIFQEEIFGPVVAVTSFTDYDDAISIANDTLYGLGAGVWSRDG
Mflv_4952|M.gilvum_PYR-GCK FTGNNTMRIFQEEIFGPVVAVTSFTDYDDAISLANDTLYGLGAGVWSRNG
Mvan_1468|M.vanbaalenii_PYR-1 FTGHNKMRIFQEEIFGPVVAVTSFTDYDDAISIANDTLYGLGAGVWSRDG
MSMEG_1543|M.smegmatis_MC2_155 FTGNNKMRIFQEEIFGPVVAVTSFSDYDDAISIANDTLYGLGAGVWSRDG
TH_3284|M.thermoresistible__bu FTGDNSMRIFQEEIFGPVVAVTSFTDYDDAIRIANDTLYGLGAGVWSRDG
MAB_2792c|M.abscessus_ATCC_199 FAGDNSMRIFQEEIFGPVLAVTSFADYDDAIAIANDTPYGLGAGVWSRNG
MLBr_02573|M.leprae_Br4923 TDITKDMALYTDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNE
: * :: :*:**** :* :: ***: :** * :***:..*:::
Mb0467|M.bovis_AF2122/97 NTAYRAGRDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGREGHQMMLQHYQ
Rv0458|M.tuberculosis_H37Rv NTAYRAGRDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGREGHQMMLQHYQ
MMAR_0780|M.marinum_M NTAYRAGRDIQAGRVWVNCYHVYPAHSAFGGYKQSGIGREGHQMMLGHYQ
MUL_1416|M.ulcerans_Agy99 NTAYRAGRDIQAGRVWVNCYHVYPAHSAFGGYKQSGIGREGHQKMLGHYQ
MAV_4691|M.avium_104 NTAYRAGRDIQAGRVWVNCYHAYPAHAAFGGYKQSGIGRENHKMMLDHYQ
Mflv_4952|M.gilvum_PYR-GCK NTAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRENHRMMLDHYQ
Mvan_1468|M.vanbaalenii_PYR-1 NTAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRENHKMMLDHYQ
MSMEG_1543|M.smegmatis_MC2_155 NIAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRETHKMMLDHYQ
TH_3284|M.thermoresistible__bu NTAYRAGRDIKAGRVWTNCYHVYPAHAAFGGYKQSGIGRENHTMMLDHYQ
MAB_2792c|M.abscessus_ATCC_199 NIAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYKRSGIGRENHKMMLDHYQ
MLBr_02573|M.leprae_Br4923 SEQRHFIDNIVAGQVFINGMTVSYPELPFGGIKRSGYGRELSTHGIREFC
. : :* **:*: * .. .*** *:** *** : .:
Mb0467|M.bovis_AF2122/97 HTKNLLVSYSDKALGFF
Rv0458|M.tuberculosis_H37Rv HTKNLLVSYSDKALGFF
MMAR_0780|M.marinum_M QTKNLLVSYSDKALGLF
MUL_1416|M.ulcerans_Agy99 QTKNLLVSYSDKPLGLF
MAV_4691|M.avium_104 QTKNMLVSYSNKAQGFF
Mflv_4952|M.gilvum_PYR-GCK QTKNLLVSYSDQALGFF
Mvan_1468|M.vanbaalenii_PYR-1 QTKNLLVSYSDKALGFF
MSMEG_1543|M.smegmatis_MC2_155 QTKNLLVSYSNKAQGFF
TH_3284|M.thermoresistible__bu QTKNLLVSYSTKAQGFF
MAB_2792c|M.abscessus_ATCC_199 QTKNLLVSYGSKAQGFF
MLBr_02573|M.leprae_Br4923 NIKTVWIA---------
: *.: ::