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M. tuberculosis H37Rv Rv3350c (PPE56)

annotation: PPE FAMILY PROTEIN
coordinates: 3755952 - 3767102
length: 3716

EFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAP
YAGWLGSVAAAAEAVAGQARVVVGVFEAALAATVDPALVAANRARLVALAVSNLLGQNTPAIAAAEAEYE
LMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVGAFLTALFASPAKALSLNAGLGNVGNYNVGLG
NVGVFNLGAGNVGGQNLGFGNAGGTNVGFGNLGNGNVGFGNSGLGAGLAGLGNIGLGNAGSSNYGFANLG
VGNIGFGNTGTNNVGVGLTGNHLTGIGGLNSGTGNIGLFNSGTGNVGFFNSGTGNFGVFNSGNYNTGVGN
AGTASTGLFNAGNFNTGVVNVGSYNTGSFNAGDTNTGGFNPGGVNTGWLNTGNTNTGIANSGNVNTGAFI
SGNFNNGVLWVGDYQGLFGVSAGSSIPAIPIGLVLNGDIGPITIQPIPILPTIPLSIHQTVNLGPLVVPD
IVIPAFGGGIGIPINIGPLTITPITLFAQQTFVNQLPFPTFSLGKITIPQIQTFDSNGQLVSFIGPIVID
TTIPGPTNPQIDLTIRWDTPPITLFPNGISAPDNPLGLLVSVSISNPGFTIPGFSVPAQPLPLSIDIEGQ
IDGFSTPPITIDRIPLTVGGGVTIGPITIQGLHIPAAPGVGNTTTAPSSGFFNSGAGGVSGFGNVGAGSS
GWWNQAPSALLGAGSGVGNVGTLGSGVLNLGSGISGFYNTSVLPFGTPAAVSGIGNLGQQLSGVSAAGTT
LRSMLAGNLGLANVGNFNTGFGNVGDVNLGAANIGGHNLGLGNVGDGNLGLGNIGHGNLGFANLGLTAGA
AGVGNVGFGNAGINNYGLANMGVGNIGFANTGTGNIGIGLVGDHRTGIGGLNSGIGNIGLFNSGTGNVGF
FNSGTGNFGIGNSGRFNTGIGNSGTASTGLFNAGSFSTGIANTGDYNTGSFNAGDTNTGGFNPGGINTGW
FNTGHANTGLANAGTFGTGAFMTGDYSNGLLWRGGYEGLVGVRVGPTISQFPVTVHAIGGVGPLHVAPVP
VPAVHVEITDATVGLGPFTVPPISIPSLPIASITGSVDLAANTISPIRALDPLAGSIGLFLEPFRLSDPF
ITIDAFQVVAGVLFLENIIVPGLTVSGQILVTPTPIPLTLNLDTTPWTLFPNGFTIPAQTPVTVGMEVAN
DGFTFFPGGLTFPRASAGVTGLSVGLDAFTLLPDGFTLDTVPATFDGTILIGDIPIPIIDVPAVPGFGNT
TTAPSSGFFNTGGGGGSGFANVGAGTSGWWNQGHDVLAGAGSGVANAGTLSSGVLNVGSGISGWYNTSTL
GAGTPAVVSGIGNLGQQLSGFLANGTVLNRSPIVNIGWADVGAFNTGLGNVGDLNWGAANIGAQNLGLGN
LGSGNVGFGNIGAGNVGFANSGPAVGLAGLGNVGLSNAGSNNWGLANLGVGNIGLANTGTGNIGIGLVGD
YQTGIGGLNSGSGNIGLFNSGTGNVGFFNTGTGNFGLFNSGSFNTGIGNSGTGSTGLFNAGNFNTGIANP
GSYNTGSFNVGDTNTGGFNPGDINTGWFNTGIMNTGTRNTGALMSGTDSNGMLWRGDHEGLFGLSYGITI
PQFPIRITTTGGIGPIVIPDTTILPPLHLQITGDADYSFTVPDIPIPAIHIGINGVVTVGFTAPEATLLS
ALKNNGSFISFGPITLSNIDIPPMDFTLGLPVLGPITGQLGPIHLEPIVVAGIGVPLEIEPIPLDAISLS
ESIPIRIPVDIPASVIDGISMSEVVPIDASVDIPAVTITGTTISAIPLGFDIRTSAGPLNIPIIDIPAAP
GFGNSTQMPSSGFFNTGAGGGSGIGNLGAGVSGLLNQAGAGSLVGTLSGLGNAGTLASGVLNSGTAISGL
FNVSTLDATTPAVISGFSNLGDHMSGVSIDGLIAILTFPPAESVFDQIIDAAIAELQHLDIGNALALGNV
GGVNLGLANVGEFNLGAGNVGNINVGAGNLGGSNLGLGNVGTGNLGFGNIGAGNFGFGNAGLTAGAGGLG
NVGLGNAGSGSWGLANVGVGNIGLANTGTGNIGIGLTGDYRTGIGGLNSGTGNLGLFNSGTGNIGFFNTG
TGNFGLFNSGSYSTGVGNAGTASTGLFNAGNFNTGLANAGSYNTGSLNVGSFNTGGVNPGTVNTGWFNTG
HTNTGLFNTGNVNTGAFNSGSFNNGALWTGDYHGLVGFSFSIDIAGSTLLDLNETLNLGPIHIEQIDIPG
MSLFDVHEIVEIGPFTIPQVDVPAIPLEIHESIHMDPIVLVPATTIPAQTRTIPLDIPASPGSTMTLPLI
SMRFEGEDWILGSTAAIPNFGDPFPAPTQGITIHTGPGPGTTGELKISIPGFEIPQIATTRFLLDVNISG
GLPAFTLFAGGLTIPTNAIPLTIDASGALDPITIFPGGYTIDPLPLHLALNLTVPDSSIPIIDVPPTPGF
GNTTATPSSGFFNSGAGGVSGFGNVGSNLSGWWNQAASALAGSGSGVLNVGTLGSGVLNVGSGVSGIYNT
SVLPLGTPAVLSGLGNVGHQLSGVSAAGTALNQIPILNIGLADVGNFNVGFGNVGDVNLGAANLGAQNLG
LGNVGTGNLGFANVGHGNIGFGNSGLTAGAAGLGNTGFGNAGSANYGFANQGVRNIGLANTGTGNIGIGL
VGDNLTGIGGLNSGAGNIGLFNSGTGNIGFFNSGTGNFGIGNSGSFNTGIGNSGTGSTGLFNAGSFNTGV
ANAGSYNTGSFNAGDTNTGGFNPGTINTGWFNTGHTNTGIANSGNVGTGAFMSGNFSNGLLWRGDHEGLF
SLFYSLDVPRITIVDAHLDGGFGPVVLPPIPVPAVNAHLTGNVAMGAFTIPQIDIPALTPNITGSAAFRI
VVGSVRIPPVSVIVEQIINASVGAEMRIDPFEMWTQGTNGLGITFYSFGSADGSPYATGPLVFGAGTSDG
SHLTISASSGAFTTPQLETGPITLGFQVPGSVNAITLFPGGLTFPATSLLNLDVTAGAGGVDIPAITWPE
IAASADGSVYVLASSIPLINIPPTPGIGNSTITPSSGFFNAGAGGGSGFGNFGAGTSGWWNQAHTALAGA
GSGFANVGTLHSGVLNLGSGVSGIYNTSTLGVGTPALVSGLGNVGHQLSGLLSGGSAVNPVTVLNIGLAN
VGSHNAGFGNVGEVNLGAANLGAHNLGFGNIGAGNLGFGNIGHGNVGVGNSGLTAGVPGLGNVGLGNAGG
NNWGLANVGVGNIGLANTGTGNIGIGLTGDYQTGIGGLNSGAGNLGLFNSGAGNVGFFNTGTGNFGLFNS
GSFNTGVGNSGTGSTGLFNAGSFNTGVANAGSYNTGSFNVGDTNTGGFNPGSINTGWLNAGNANTGVANA
GNVNTGAFVTGNFSNGILWRGDYQGLAGFAVGYTLPLFPAVGADVSGGIGPITVLPPIHIPPIPVGFAAV
GGIGPIAIPDISVPSIHLGLDPAVHVGSITVNPITVRTPPVLVSYSQGAVTSTSGPTSEIWVKPSFFPGI
RIAPSSGGGATSTQGAYFVGPISIPSGTVTFPGFTIPLDPIDIGLPVSLTIPGFTIPGGTLIPTLPLGLA
LSNGIPPVDIPAIVLDRILLDLHADTTIGPINVPIAGFGGAPGFGNSTTLPSSGFFNTGAGGGSGFSNTG
AGMSGLLNAMSDPLLGSASGFANFGTQLSGILNRGAGISGVYNTGALGVVTAAVVSGFGNVGQQLSGLLF
TGVGP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3350cPPE56-100% (3716)PPE FAMILY PROTEIN
M. tuberculosis H37RvRv3347cPPE550.067.17% (3019) PPE family protein
M. tuberculosis H37RvRv3343cPPE540.044.62% (2530) PPE family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3380cPPE55a0.064.35% (1902) hypothetical protein Mb3380c
M. gilvum PYR-GCKMflv_0325-4e-2636.08% (194) PPE protein
M. leprae Br4923MLBr_01182-3e-3244.71% (170) PPE-family protein
M. abscessus ATCC 19977MAB_0669-1e-2536.05% (172) PPE-family protein
M. marinum MMMAR_4621-0.037.64% (3746) PPE family protein
M. avium 104MAV_4704-7e-5457.21% (201) PPE family protein
M. smegmatis MC2 155MSMEG_0868-2e-2828.27% (902) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3113-1e-2940.41% (193) PUTATIVE PPE protein
M. ulcerans Agy99MUL_0782-1e-13655.39% (464) PPE family protein
M. vanbaalenii PYR-1Mvan_0415-1e-2736.32% (201) PPE protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0325|M.gilvum_PYR-GCK          MTSPVASLAPVTSPVWMALPPEVHSTMLSSGPGP---------------G
Mvan_0415|M.vanbaalenii_PYR-1       ----------MSSPVWMALPPEVHSALLSSGPGP---------------G
MAB_0669|M.abscessus_ATCC_1997      ----------MTAPIWMAEPPEVHSALLSAGPGP---------------G
TH_3113|M.thermoresistible__bu      ----------------MALPPEVHSTLLRTGPGP---------------G
MLBr_01182|M.leprae_Br4923          ------------MFDFAALSPETNSTRMYLGPGS---------------S
Rv3350c|M.tuberculosis_H37Rv        -------------MEFPVLPPEINSVLMYSGAGS---------------S
Mb3380c|M.bovis_AF2122/97           -------------MNFPVLPPEINSVLMYSGAGS---------------S
MAV_4704|M.avium_104                ----------MTNPHFAWLPPEVNSALIYSGPGP---------------G
MMAR_4621|M.marinum_M               -------------MSFSVSPPEINSARIFSGAGS---------------G
MUL_0782|M.ulcerans_Agy99           -------------MNFSVLPPEVNSALIFTGPGA---------------E
MSMEG_0868|M.smegmatis_MC2_155      -----------MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRK
                                                       .   ...    . *.                

Mflv_0325|M.gilvum_PYR-GCK          SLLAAGVAWQSLSAEYASAAAELTSILAGVQSGAWEGPSSQQYVAAHTPY
Mvan_0415|M.vanbaalenii_PYR-1       SMLAAAATWQSLSAEYAAAAAELSSILADVQAGAWEGPSSEQYVAAHTPY
MAB_0669|M.abscessus_ATCC_1997      AVLAAAVQWQEIGNNYANTAVELAQVLAGVRAGSWQGPSASEYVAAHLPY
TH_3113|M.thermoresistible__bu      ALSAAADAWRMLSDEYRAAAVELAAVVSQTCATAWEGVGADAYAAAHGPY
MLBr_01182|M.leprae_Br4923          PILTAAAAWVVLAKELTAAAQGLQSAVEALLT-TFEGESAAALAERVTPY
Rv3350c|M.tuberculosis_H37Rv        PLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAPY
Mb3380c|M.bovis_AF2122/97           PLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAPY
MAV_4704|M.avium_104                PLLAAAAAWDGLAEELASSAQSFSSVTSDLASGSWQGASSAAMMTVANQY
MMAR_4621|M.marinum_M               PLLSAAAAWDGLAGELGSAAATFSSVTSALTGSSWQGPASAAMANVASGY
MUL_0782|M.ulcerans_Agy99           PMRTAATAWGGMAVELESAADSFASVTSGLVGGAWQGASSVAMGTAAASY
MSMEG_0868|M.smegmatis_MC2_155      PKFPAALAPESPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQ
                                    .  .*.        :                    :  .           

Mflv_0325|M.gilvum_PYR-GCK          LAWLAQQSAVSAATAVQHDTAAAAYTTALATMPTLPELALNHTTHAVLVG
Mvan_0415|M.vanbaalenii_PYR-1       LAWLAQQSAAGAAAAAQHEAAAAAYSTALATMPTLPELALNHTTHAVLVA
MAB_0669|M.abscessus_ATCC_1997      LAWLEQAAAESSVIAAQHETTAAAYNSALAAMPTLAELAANHITHGVLVG
TH_3113|M.thermoresistible__bu      LFWLTDTAAAAAAAGAQLEAAAAAHASALAAMPTMAELTANRTTHAALVA
MLBr_01182|M.leprae_Br4923          EKWLTQNAASAELTATQLTVAANAYETAFTMTVPPLMVFVNRAQACLLIM
Rv3350c|M.tuberculosis_H37Rv        AGWLGSVAAAAEAVAGQARVVVGVFEAALAATVDPALVAANRARLVALAV
Mb3380c|M.bovis_AF2122/97           AGWLGSVAAQAVAVAGQARAAVAAFEAALAATVDPAAVAVNRMAMRALAM
MAV_4704|M.avium_104                VSWLSAAAAQAEEVSHQASAIATAFEVALAATVQPAVVAANRALVQALAA
MMAR_4621|M.marinum_M               LGWLASTGVQAGQAASQARIAAAAFEATVAATVHPVAVLANRTQLVSLVT
MUL_0782|M.ulcerans_Agy99           LGWLNAAAAHAEQAAAQAEALVAEFAAAQSAMVQPFLLAANRSSLVSLVL
MSMEG_0868|M.smegmatis_MC2_155      ATSTNTTDQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSV
                                                                 .           :     *  

Mflv_0325|M.gilvum_PYR-GCK          TNFLGINTIPIALNEADYVRMWIQAATTMATYQSVSGAALAATPTSAPAP
Mvan_0415|M.vanbaalenii_PYR-1       TNFLGINTIPIAMTEADYVRMWIQAATTMATYQAVSGAALAATPTATPAP
MAB_0669|M.abscessus_ATCC_1997      TNFFGINTIPIALNEADYVRMWVQAAATMSAYQATTEAMTSAIPPTQQPP
TH_3113|M.thermoresistible__bu      TNFFGVNTIPIAVNEADYARMWIQAATTMATYEAVASAAVSATPRTVAPP
MLBr_01182|M.leprae_Br4923          SNIFGQNSTAIAEKEAEYTEMWIQDAAAMTSYQASVLEAVGATKAFTAPP
Rv3350c|M.tuberculosis_H37Rv        SNLLGQNTPAIAAAEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPA
Mb3380c|M.bovis_AF2122/97           SNLLGQNAAAIAAVEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPA
MAV_4704|M.avium_104                TNWLGQNTPAIADIEAAYEQMWASDVAAMFGYHADASAAVAKLPPWNEVL
MMAR_4621|M.marinum_M               SNLLGFNAPAIATVEAEYEQMWAQDVAAMFGYHTGASAAVAALTPFTQVL
MUL_0782|M.ulcerans_Agy99           SNLFGQNAPAIEAVEAEYEQMWALDVSTMATYHAGASAAAASLTPLAQPL
MSMEG_0868|M.smegmatis_MC2_155      VTLGTTLIPNAPTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLP
                                     .             *    :*   . :                      

Mflv_0325|M.gilvum_PYR-GCK          SVLLPGVGEAGRAAADMSAFAAQPMAAQAGAAFDVSNI------------
Mvan_0415|M.vanbaalenii_PYR-1       FVLAPGVGEAGRAAADVTAFAAQAQAAEAGSALDLSNI------------
MAB_0669|M.abscessus_ATCC_1997      AILSPG-GEARSDQSDVPGSPDQIMKMLQG--------------------
TH_3113|M.thermoresistible__bu      PILGAGTGESATAAITGAHVTAELRAAESRTLLDEIN-------------
MLBr_01182|M.leprae_Br4923          LGVNEVGLAQEVVEEVVEEVVEEVVEAEQA--------------------
Rv3350c|M.tuberculosis_H37Rv        QALGGGVGAFLTALFASPAKALSLNAGLGNVGNYNVGLGNVGVFNLGAGN
Mb3380c|M.bovis_AF2122/97           QALGGGVGAFLNAIFAGPAKMLRLNAGLGNVGNYNVGLGNVGIFNLGAAN
MAV_4704|M.avium_104                QNLG----------FSNASTAVTRPAGSGAVARGYTSR-IAGFLAPRAPQ
MMAR_4621|M.marinum_M               QSPAAAAAAVQTAIIDFPGRTNIFNAGLGNLGVGNVGFASVGDGNVGGGN
MUL_0782|M.ulcerans_Agy99           QN-----------LSELPGR------------------------------
MSMEG_0868|M.smegmatis_MC2_155      VPTVASAVLDPTQIVNWLIYQPLHAAGQQFWVVSPIGS------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        VGGQNLGFGNAGGTNVGFGNLGNGNVG---FGNSGLGAGLAGLGNIGLGN
Mb3380c|M.bovis_AF2122/97           VGAQNLGAANAGSGNFGFGNIGNANFG---FGNSGLGL-PPGMGNIGLGN
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               LGDGNVGFGNVGGLNFGSGNWGGFNLGSGNIGSYNFGPGNLGSYNIGFGN
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        AGSSNYGFANLGVGNIGFGNTGTNNVGVGLTGNHLTGIGGLNSGTGNIGL
Mb3380c|M.bovis_AF2122/97           AGSSNYGLANLGVGNIGFANTGSNNIGIGLTGDNLTGIGGLNSGTGNLGL
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               AGDYNVGFGNSGLGNIGFGNSGSNNLGIGLTGSGQVGFGGWNSGSGNVGL
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        FNSGTGNVGFFNSGTGNFGVFNSGNYNTGVGNAGTASTGLFNAGNFNTGV
Mb3380c|M.bovis_AF2122/97           FNSGTGNIGFFNSGTGNFGVFNSGSYNTGVGNAGTASTGLFNVGGFNTGV
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               FNSGVGNVGLFNSGTGNWGVGNSGEFDTGLFNAGRYNTGVFNSGVLNTGV
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          ----------------------------------------IADIIRLYGE
Mvan_0415|M.vanbaalenii_PYR-1       ----------------------------------------IADLIRAYGE
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      -------------------------------------------------E
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        VNVGSYNTGSFNAGDTNTGGFNPGGVNTGWLNTGNTNTGIANSGNVNTGA
Mb3380c|M.bovis_AF2122/97           ANVGSYNTGSFNAGNTNTGGFNPGNVNTGWLNTGNTNTGIANSGNVNTGA
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GNAGDYNSGSFNTGASNTGDLNAGDTNTGWANTGNLNTGFGNSGHLNTGG
MUL_0782|M.ulcerans_Agy99           -----------------------------------VIAAFGN--------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          VLRFLFEPIFNFLRDPIGNTFALITDFLTNPVQALITWGPFLLAVVYQAV
Mvan_0415|M.vanbaalenii_PYR-1       LLRFLFEPIFDFLRDPLGNTIKLITDFLTNPAQALITWGPFLAAVAYQAV
MAB_0669|M.abscessus_ATCC_1997      -FQQWFEKMG--FNPATSAVLAVIMLFLYD-----LLWYPYYAS------
TH_3113|M.thermoresistible__bu      LIDRLFAPLFP-PGFADALPDGLLGTLLAPLLPGATGDGPPMATIMSFLL
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        FISGNFNNGVLWVGDYQGLFGVSAGSSIPAIPIGLVLNGDIGPITIQPIP
Mb3380c|M.bovis_AF2122/97           FISGNFSNGVLWRGDYEGLWGLSGGSTIPAIPIGLELNGGVGPITVLPIQ
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               FNQGSQNNGFFWRGDAQGQIGFDYTITIPEIGLGLNVDVPLNIPLRGTIG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------TLGGVINTISGQYLIGNGINGTADNPNGGTG-----
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          SWVGASILYPSLFLLPLLATTLAIVAGVG---------------------
Mvan_0415|M.vanbaalenii_PYR-1       SWVGASILYPSLLLLPLVATTLAIVLGVG---------------------
MAB_0669|M.abscessus_ATCC_1997      ------------YLLPFLIPALSGLSGL----------------------
TH_3113|M.thermoresistible__bu      MGLSNPAYLFPVLVYLLFTGVVHTTVAVS---------------------
MLBr_01182|M.leprae_Br4923          -----------------ISQAALDQAVNE---------------------
Rv3350c|M.tuberculosis_H37Rv        ILPTIPLSIHQTVNLGPLVVPDIVIPAFG-GGIGIPINIGPLTITPITLF
Mb3380c|M.bovis_AF2122/97           ILPTIPLNIHQTFSLGPLVVPDIVIPAFG-GGTAIPISVGPITISPITLF
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               TL---------IDGEPIISVPGFTIPALHLDGTALSGTIGPIVVDPITIT
MUL_0782|M.ulcerans_Agy99           -------------GAPATTVT-AAVTALR---------------------
MSMEG_0868|M.smegmatis_MC2_155      ----------------GLLFGDGGHGYDG---------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        AQQTFVNQLPF-PTFSLGKITIPQIQTFDSNGQLVSFIGPIVIDTTIPGP
Mb3380c|M.bovis_AF2122/97           PAQNFNTTFPVGPFFGLGVVNISGIEIKDLAGNVTLQLGNLNIDTRIN--
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GPQVDLMVGGPGESLQL---------------------------------
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        TNPQIDLTIRWDTPPITLFPNGISAPDNPLGLLVSVSISNPGFTIPGFSV
Mb3380c|M.bovis_AF2122/97           --QSFPVTVNWSTPAVTIFPNGISIPNNPLALLASASIGTLGFTIPGFTI
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               --------------------------------------------------
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        PAQPLPLSIDIEGQIDGFSTPPITIDRIPLTVGGGVTIGPITIQGLHIPA
Mb3380c|M.bovis_AF2122/97           PAAPLPLTIDIDGQIDGFSTPPITIDRIPLNLGASVTVGPILINGVNIPA
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               -------------------------------ALSGPGVGPVVIPVAHVPA
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        APGVGNTTTAPSSGFFNSGAGGVSGFGNVGAGSSGWWNQAPSALLGAGSG
Mb3380c|M.bovis_AF2122/97           TPGFGNTTTAPSSGFFNSGDGGVSGFGNFGAGSSGWWNQAQTEVAGAGSG
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               VAGFGNTTSAPSSGFFNSGTGSSSGFGNV-GGGSGWWNFASGGVG--YSG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          -------------------------------QHLLSLLNTPPAEEAAEEP
Mvan_0415|M.vanbaalenii_PYR-1       -------------------------------AYLLENLPAPAEDAPAEEP
MAB_0669|M.abscessus_ATCC_1997      -------------------------------AALMHLRPAAPGPVPAAAL
TH_3113|M.thermoresistible__bu      -------------------------------GMLAQLVPLMPALLPVAVA
MLBr_01182|M.leprae_Br4923          -------------------------------GMEATVVPQVDQQVNVDVA
Rv3350c|M.tuberculosis_H37Rv        VGNVGTLGSGVLNLGSGISGFYNTSVLPFGTPAAVSGIGNLGQQLSGVSA
Mb3380c|M.bovis_AF2122/97           FANFGSLGSGVLNFGSGVSGLYNTGGLPPGTPAVVSGIGNVGEQLSGLSS
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               VGNVGALGSGVFNLGDGVSGWVNT------IPSMGSGVGNVGDGLAGLFS
MUL_0782|M.ulcerans_Agy99           ------------------------------LPADASTVN-----------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------SAAGLAGGNGGNAGLFGN
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          APAQSAPSRPDQQSFPATMSAPPPPSGAPIAAN-TVSAGSPPAPG---AP
Mvan_0415|M.vanbaalenii_PYR-1       AASSPAPTRADQPSPAIAVSAPPPPSSAAATVG-TVATGTAPAPG---AP
MAB_0669|M.abscessus_ATCC_1997      SPGDRPIRRPTQHVEPNLAALPLPTSSVVPSGGSSVPVSTPTAPAHTVSS
TH_3113|M.thermoresistible__bu      ALGGLAGVWAGLSGLAGLAGLTAVPAADGGASAAPVPAGGPSLPSG--SS
MLBr_01182|M.leprae_Br4923          TPQTAVPDSSSAAAPQLWGGFAQHLSPINDTLSMINNHAGMANAG-----
Rv3350c|M.tuberculosis_H37Rv        AGTTLRSMLAGNLGLANVGNFNTGFGNVGDVNLGAANIGGHNLGLGNVGD
Mb3380c|M.bovis_AF2122/97           AGTALNQSLIINLGLADVGSVNVGFGNVGDFNLGAANIGDLNVGLGNVGG
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               QGADK--ISVFGLGVANHGGLNVGSANVGDANLGSANVGSANVGGGNVGG
MUL_0782|M.ulcerans_Agy99           ------------FGLANIGSGNVGNANNGIGNLGSGNLGNFNLGSGNLGS
MSMEG_0868|M.smegmatis_MC2_155      GGNGGVGWAGLDGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGT
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          AAAAATFVPYVVAGRDP-Y-------------EGFSPTVRDSTGAKAPAG
Mvan_0415|M.vanbaalenii_PYR-1       AAATASFVPYAVAGRDP-G-------------TGFSPTVRDSTSAKAPAS
MAB_0669|M.abscessus_ATCC_1997      VPAPSAAISYAIPGLVPPG-------------VSFGPKSTEKSSESAVDT
TH_3113|M.thermoresistible__bu      APPAPTGSAAPTTGTAPGG-------------AGSPPPAG-HSVPPAPHS
MLBr_01182|M.leprae_Br4923          -LSLVNGMGSAMKSLAP------------------TTTKAAESAFKAMGS
Rv3350c|M.tuberculosis_H37Rv        GNLGLGNIGHGNLGFANLG---LTAGAAGVGNVGFGNAGINNYGLANMGV
Mb3380c|M.bovis_AF2122/97           GNVGFGNIGDANFGLGNAG---LAAGLAGVGNIGLGNAGSGNVGFGNMGV
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GNVGVANVGDGNVGGANVGGANVGGANTGDGNWGWGNTGGGNIGWGNTGV
MUL_0782|M.ulcerans_Agy99           SNAGWANLGSNNIGGANSGGNNLG----------WGNLGGLNTGFANAGS
MSMEG_0868|M.smegmatis_MC2_155      GGTGGGTGGTGGIGGTGGGLFGLLG--------HSGSTGAAGAAGNGGDG
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          TIPAAASG-----IAASAAERRKRRRRQKEEIKGRGYADAYADYEELPDD
Mvan_0415|M.vanbaalenii_PYR-1       GIPAAASG-----VAASAAERRKRRRRQKDEIAGRAYADAYADYEPEPDD
MAB_0669|M.abscessus_ATCC_1997      VAAVAAAR-----GAVAAQARRRLRGKNKAEAGGR--RHEYLEETAGMG-
TH_3113|M.thermoresistible__bu      APPVGTSGPPYLIAAQPAPGVARRSAGARRAASIVEPAGSAAAAAAARES
MLBr_01182|M.leprae_Br4923          AVQSTGRG----LLGSSSGGHVTAQLGRAASIGSLRVPQTWTTASQPVTA
Rv3350c|M.tuberculosis_H37Rv        GNIGFANTGTGNIGIGLVGDHRTGIGGLNSGIGNIGLFNSGTGNVGFFNS
Mb3380c|M.bovis_AF2122/97           GNIGFGNTGTNNLGIGLTGDNQTGIGGLNSGAGNIGLFNSGTGNVGLFNS
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GNFGFGNQGSGNIGIGLSGDHQVGFGGWNSGSGNVGLFNSGDGNIGFFNS
MUL_0782|M.ulcerans_Agy99           GNFRFANTGNNNIGIGLTGDNQVGIGGLNSGVGNFGLFNSGTGNVGLFNS
MSMEG_0868|M.smegmatis_MC2_155      GNGGFGYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGG
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          GPPEQPAPRVTASTRGAGPMGFAGTVSRGD-EQAGGLTTLAGDSFGGGPR
Mvan_0415|M.vanbaalenii_PYR-1       EPPVRQEPRIAATERGAGPMGFAGTVSRDA-AQAGGLTTLPGDPFGGGPK
MAB_0669|M.abscessus_ATCC_1997      ATATADVPAYAATGRGTGPLGFAGTAPAAASTHVAATVRLSSD--EARQV
TH_3113|M.thermoresistible__bu      APIRRRRGQKDGLHGHRHEHQQPASMSAATAPSAAGIRVLGGAGRISRTR
MLBr_01182|M.leprae_Br4923          ATRALSPARVAVATESESAPLLGGGLPMAP-MVPGGGSGTGGVNTALRLQ
Rv3350c|M.tuberculosis_H37Rv        GTGNFGIGNSGRFNTGIGNSGTASTGLFNAGSFSTGIANTGDYNTGSFNA
Mb3380c|M.bovis_AF2122/97           GTGNFGLFNSGGYNTGIGNGGTGSTGLFNAGNFNTGVANPGSYNTGSFNV
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GSGNFGIANSGSFNTGIANAGLTNTGWFNSGLANTGWGNAGAYNSGGFNA
MUL_0782|M.ulcerans_Agy99           GTGNFGIGNSGAYGTGLFNSGQANT-------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGAILIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGT
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          EPMLPGTWDPDATDDRHTDGRDGHDGHDGKEKP-----------------
Mvan_0415|M.vanbaalenii_PYR-1       APMLPGTWDPDTEPD------ERHNHHDGKDSQ-----------------
MAB_0669|M.abscessus_ATCC_1997      IPMLPSTWDADGGDQN----------------------------------
TH_3113|M.thermoresistible__bu      GSVPHAEITPGDPTEPSSPTDRAHRPAEPN--------------------
MLBr_01182|M.leprae_Br4923          PRAFVMPRNPAAG-------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GDTNTGGFNPGGINTGWFNTGHANTGLANAGTFGTGAFMTGDYSNGLLWR
Mb3380c|M.bovis_AF2122/97           GDTNTGGFNPGSINTGWFNTGNANTGVANSGTVNTGAFIT----------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GAYNTGSFNPGHVNTGWFNTGDTNTGLGNSGNINTGAFVSGDMNNGFFWR
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSG---------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GGYEGLVGVRVGPTISQFPVTVHAIGGVGPLHVAPVPVPAVHVEITDATV
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GTGQGLIGADYTITIPQIPLTIGGGGILNIPITGAITGLTVQPFTVHG--
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GLGPFTVPPISIPSLPIASITGSVDLAANTISPIRALDPLAGSIGLFLEP
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               --------------------------------------------------
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        FRLSDPFITIDAFQVVAGVLFLENIIVPGLTVSGQILVTPTPIPLTLNLD
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               -----------------------------------VGTSTTGIPLDLQVT
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        TTPWTLFPNGFTIPAQTPVTVGMEVANDGFTFFPGGLTFPRASAGVTGLS
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               ILGADTNEIGVDVHIPKPIDKDVTVPIPSIPVLNLGVTIDNEIGAIVAPE
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        VGLDAFTLLPDGFTLDTVPATFDGTILIGDIPIPIIDVPAVPGFGNTTTA
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               IAINPINFNKFMIGNEDSPLTVHIGGGAGPVTIPVFHLSPTPGFGNSGGA
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        PSSGFFNTGGGGGSGFANVGAGTSGWWNQGHDVLAGAGSGVANAGTLSSG
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               PSSGFFNSGDGVS------GFGNFGATVSGWGNVASHASGFENFGTGLSG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        VLNVGSGISGWYNTSTLGAGTPAVVSGIGNLGQQLSGFLANGTVLNRSPI
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               FTNVGDALSGLKNTNSSGLGTSGVGNVGDSLS------------------
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        VNIGWADVGAFNTGLGNVGDLNWGAANIGAQNLGLGNLGSGNVGFGNIGA
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               --------------------------------------------------
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GNVGFANSGPAVGLAGLGNVGLSNAGSNNWGLANLGVGNIGLANTGTGNI
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               --------------------------------------------------
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GIGLVGDYQTGIGGLNSGSGNIGLFNSGTGNVGFFNTGTGNFGLFNSGSF
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               ------------GLFYAGPDRMSIFNAGLGNLGVGNVGFASVGDGNVGGG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        NTGIGNSGTGSTGLFNAGNFNTGIANPGSYNTGSFNVGDTNTGGFNPGDI
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               NLGDGNVGFGNVGGLNFGSGNWGGFNLGSGNIGSYNFGPGNLGSYNIGFG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        NTGWFNTGIMNTGTRNTGALMSGTDSNGMLWRGDHEGLFG------LSYG
Mb3380c|M.bovis_AF2122/97           ----------------------GNDSNGILWRGNFEGLFG------LNVG
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               NAGDYNVGFGNSGLGNIGFGNSGSNNLGIGLTGSGQVGFGGWNSGSGNVG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        ITIPQFPIRITTTGGIGPIVIPDTTILPPLHLQITGDADYSFTVPDIPIP
Mb3380c|M.bovis_AF2122/97           ITIPEFPIHWTSTGGIGPIIIPDTTILPPIHLGLTGQANYGFAVPDIPIP
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               LFNSGVGNVGLFNSGTGNWGVGNSGEFDTGLFNAGRYNTGVFNSGVLNTG
MUL_0782|M.ulcerans_Agy99           -----------------------------GLLNAGSFNTGLLDVGNANTG
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------TATGGRGGDGIDGGTGGAG
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        AIHIGINGVVTVGFTAPEATLLSALKNNGSFISFGPITLSNIDIPPMDFT
Mb3380c|M.bovis_AF2122/97           AIHIDFDGAADAGFTASATTLLSALGITGQFR-FGPITVSNVQLNPFNVN
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               VGNAGDYNSGSFNTGASNTGDLNAGDTNTGWANTGNLNTGFGNSG--HLN
MUL_0782|M.ulcerans_Agy99           SLNTGSFNMGSFNPGPSNTGALNTGTANTGWFNTGSLNTGPFNIG--DMN
MSMEG_0868|M.smegmatis_MC2_155      GMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGG
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        LGLPVLG----------PITGQLG-PIHLEPIVVAGIGVPLE--IEPIPL
Mb3380c|M.bovis_AF2122/97           LKLQFLHDAFPNEFPDPTISVQIQVAIPLTSATLGGLALPLQQTIDAIEL
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               TGGFNQGSQNNGFFWRGDAQGQIGFDYTLTVPEIG-LNIDANIPINIPVA
MUL_0782|M.ulcerans_Agy99           NGLFNTGEMNNGIFYRGVGQG--NFYFSITTPDL----------------
MSMEG_0868|M.smegmatis_MC2_155      KASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAA
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        DAISLSESIPIRIP-VDIPASVIDGISMSEVVPIDASVDIPAVTITGTTI
Mb3380c|M.bovis_AF2122/97           PAISFSQSIPIDIPPIDIPASTINGISMSEVVPIDVSVDIPAVTITGTRI
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               ATLGVIKVGTFTIPTLYLNGNNLTGT-IGPIVVDPITITGPQVDLMVGGP
MUL_0782|M.ulcerans_Agy99           -TLPPLEIPGITIPNLSLP---------------PITMRR----------
MSMEG_0868|M.smegmatis_MC2_155      SANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNG---------G
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        SAIPLGFDIRTSAGPLNIPIIDIPAAPGFGNSTQMPSSGFFNTGAGGGSG
Mb3380c|M.bovis_AF2122/97           DPIPLNFDVLSSAGPINISIIDIPALPGFGNSTELPSSGFFNTGGGGGSG
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GESLQLALSGPGVGPVVIPVAHVPAVAGFGNTTSAPSSGFFNSGTGSSSG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      NGGNGWVQAYDPNGPAGTTIDKGKAAGGNG------GDGGFNGTGGATGG
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        IGNLGAGVSGLLNQAGAGSLVGTLSGLGNAGTLASGVLNSGTAISGLFNV
Mb3380c|M.bovis_AF2122/97           IANFGAGVSGLLNQASS-PMVGTLSGLGNAGSLASGVLNSGVDISGMFNV
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               FGNVGGGSGWWN----FASGGVGYSGVGNVGALGSGVFNLGDGVSGWVNT
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      RGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGG
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        STLDATTPAVISGFSNLGDHMSGVSIDGLIAILTFP-PAESVFDQIIDAA
Mb3380c|M.bovis_AF2122/97           STLGS-APAVISGFGNLGNHVSGVSIDGLLAMLTSGGSGGSGQPSIIDAA
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               ------IPSMGSGVGNVGDGLAGLFSQGADKISVFG--------------
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      AGGVSEGEGGTGGHGGDGGRGGDGALGG----------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        IAELQHLDIGNALALGNVGGVNLGLANVGEFNLGAGNVGNINVGAGNLGG
Mb3380c|M.bovis_AF2122/97           IAELRHLNPLNIVNLGNVGSYNLGFANVGDVNLGAGNLGNLNLGGGNLGG
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               ------------LGVANHGGLNVGSANVGDANLGSANVGSANVGGGNVGD
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ---------------------NGGTGGVGLGNGGKGGNGGNGGNGGTYVD
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        SNLGLGNVGTGNLGFGNIGAGNFGFGNAGLTAGAGGLGNVGLGNAGSGSW
Mb3380c|M.bovis_AF2122/97           QNLGLGNLGDGNVGFGNLGHGNVGFGNSGLGALPG-IGNIGLGNAGSNNV
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GNVGVANVGDGNVGGANVGGANVGGANTGD-------GNWGWGNTGGGNI
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      PSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKG
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GLANVGVGNIGLANTGTGNIGIGLTGDYRTGIGGLNSGTGNLGLFNSGTG
Mb3380c|M.bovis_AF2122/97           GFGNMGLGNIGFGNTGTNNLGIGLTGDNQTGFGGLNSGAGNLGLFNSGTG
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GWGNTGVGNFGFGNQGSGNIGIGLSGDHQVGFGGWNSGSGNVGLFNSGDG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVV
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        NIGFFNTGTGNFGLFNSGSYSTGVGNAGTASTGLFNAGNFNTGLANAGSY
Mb3380c|M.bovis_AF2122/97           NIGFFNTGTGNWGLFNSGSYNTGIGNSGTGSTGLFNAGSFNTGLANAGSY
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               NIGFFNSGSGNFGIANSGSFNTGIANAGLTNTGWFNSGLANTGWGNAGAY
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      QANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIG-AGGN
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        NTGSLNVGSFNTGGVNPGTVNTGWFNTGHTNTGLFNTGNVNTGAFNSGSF
Mb3380c|M.bovis_AF2122/97           NTGSLNAGNTNTGGFNPGNVNTGWFNAGHTNTGGFNTGNVNTAAFNSGSF
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               NSGGFNAGAYNTGSFNPGHVNTGWFNTGDTNTGLGNSGNINTGAFVSGDM
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGG
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        NNGALWTGDYHGLVGFSFSIDIAGSTLLDLNETLNLGPIHIEQIDIPGMS
Mb3380c|M.bovis_AF2122/97           NNGALWTGDHHGLVGFSYSIEITGSTLVDINETLNLGPVHIDQIDIPGMS
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               NNGFFWRGTGQGLIGADYTITIP------------HIPITVGGGGILKLP
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      NGGPSWVQSGYG--------------------------------STLGGN
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        LFDVHEIVEIGPFTIPQVDVPAIPLEIHESIHMDPIVLVPATTIPAQTRT
Mb3380c|M.bovis_AF2122/97           LFDIHELVNIGPFRIEPIDVPAVVLDIHETMVIPPIVFLPSMTIGGQTYT
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               LTGEISNLKVEPFGLRGEGGGGIPLIAHFTLLG-----------------
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ATGTATAGKGGEASNGGVAGNGG---------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        IPLDIPASPGS-TMTLPLISMRFEGEDWILGSTAAIPNFGDPFPAPTQGI
Mb3380c|M.bovis_AF2122/97           IPLDTPPAPAPPPFRLPLLFVNALGDNWIVGASNSTGMSGGFVTAPTQGI
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               --------------------------------------------------
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        TIHTGPGPGTTGELKISIPGFEIPQIATTRFLLDVNISGGLPAFTLFAGG
Mb3380c|M.bovis_AF2122/97           LIHTGPSSATTGSLALTLPTVTIPTITTSPIPLKIDVSGGLPAFTLFPGG
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               -----DTKATTIDIPGTSLSFELPSLP---VAIKVDIN------------
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        LTIPTNAIPLTIDASGALDPITIFPGGYTIDPLPLHLALNLTVPDSSIPI
Mb3380c|M.bovis_AF2122/97           LNIPQNAIPLTIDASGVLDPITIFPGGFTIDPLPLSLALNISVPDSSVPI
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               -----DELSVISTPEITINPITFNEFVIGSDETPFDVSIDGGIEPLTVTV
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ------------------NALVMAAGTTGVATGNTATGGDGGAATTAGAT
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        IDVPPTPGFGNTTATPSSGFFNSGAGGVSGFGNVGSNLSGWWNQAASALA
Mb3380c|M.bovis_AF2122/97           IIVPPTPGFGNATATPSSGFFNSGAGGVSGFGNFGAGSSGWWNQAHAALA
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               FHLSPTPGFGNSGGAPSSGFFNSGDG-VSGFGNFGATVSGWG-----NVA
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGP
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GSGSGVLNVGTLGSGVLNVGSGVSGIYNTSVLPLGTPAVLSGLGNVGHQL
Mb3380c|M.bovis_AF2122/97           GAGSGVLNVGTLNSGVLNVGSGISGLYNTAIVGLGTPALVSGAGNVGQQL
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               SHASGFENFGSGLSGFTNVGDVLSGLKNTNSSGLGT----SGVGNVGDSL
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      VGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGE
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        SGVSAAGTALNQIPILNIGLADVGNFNVGFGNVGDVNLGAANLGAQNLGL
Mb3380c|M.bovis_AF2122/97           SGVLAAGTALTQSPIINLGLADVGNYNLGLGNVGDFNLGAANLGDLNLGL
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               SGLFYA--GPDRMSIFNAGLGNLGVGNVGFASVGDGNVGGGNLGDGNVGF
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      HNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGG
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GNVGTGNLGFANVGHGNIGFGNSG---LTAGAAGLGNTGFGNAGSANYGF
Mb3380c|M.bovis_AF2122/97           GNIGNANVGFGNIGHGNVGFGNSG---LGR-----------RSASAISGW
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GNVGGLNFGSGNWGGFNLGSGNIGSYNFGPGNLGSYNIGFGNAGDYNVGF
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      NGGADGTPGTAGTTGANNP-------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        ANQGVRNIGLANTGTGNIGIGLVGDNLTGIGGLNSGAGNIGLFNSGTGNI
Mb3380c|M.bovis_AF2122/97           AMRAAPTLAWP---------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GNSGLGNIGFGNSGSNNLGIGLTGSGQVGFGGWNSGSGNVGLFNSGDGNV
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GFFNSGTGNFGIGNSGSFNTGIGNSGTGSTGLFNAGSFNTGVANAGSYNT
Mb3380c|M.bovis_AF2122/97           --------TWVWATSGSPTPAPTTSGLGWP-------ATTRPASAA----
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GLFNSGTGNWGVGNSGEFDTGLFNAGRYNTGVFNSGVLNTGVGNAGDYNS
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GSFNAGDTNTGGFNPGTINTGWFNTGHTNTGIANSGNVGTGAFMSGNFSN
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GSFNTGASNTGDLNAGDTNTGWANTGNLNTGFGNSGHLNTGGFNQGSQNN
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GLLWRGDHEGLFSLFYSLDVPRITIVDAHLDGGFGPVVLPPIPVPAVNAH
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GFFWRGDAQGQIGFDYTITIPEIAVG-----------FNVQVPLDIPLSG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        LTGNVAMGAFTIPQIDIPALTPNITGSAAFRIVVGSVRIPPVSVIVEQII
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               HLGEIRLSEFMLPPIHLNPVDGNSLTGTIGPIVVDPITITGP--------
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        NASVGAEMRIDPFEMWTQGTNGLGITFYSFGSADGSPYATGPLVFGAGTS
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               --------------------------------------------------
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        DGSHLTISASSGAFTTPQLETGPITLGFQVPGSVNAITLFPGGLTFPATS
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               --------------------------------------------------
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        LLNLDVTAGAGGVDIPAITWPEIAASADGSVYVLASSIPLINIPPTPGIG
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               -----------QVDLMVGGPGESLQLALSGPGVGPVVIPVAHVPAVAGFG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        NSTITPSSGFFNAGAGGGSGFGNFGAGTSGWWNQAHTALAGAGSGFANVG
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               NTTSAPSSGFFNSGTGSSSGFGNVGGGSGWWN---FASGGVGYSGVGNVG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        TLHSGVLNLGSGVSGIYNTSTLGVGTPALVSGLGNVGHQLSGLLSGGSAV
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               ALGSGVFNLGDGVSGWVNT------IPSMGSGVGNVGDGLAGLFSQGADK
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        NPVTVLNIGLANVGSHNAGFGNVGEVNLGAANLGAHNLGFGNIGAGNLGF
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               --ISVFGLGVANHGGLNVGSANVGDANLGSANVGSANVGGGNVGDGNVGV
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GNIGHGNVG---VGNSGLTAGVPGLGNVGLGNAGGNNWGLANVGVGNIGL
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               ANVGDGNVGGANVGGANVGGANTGDGNWGWGNTGGGNIGWGNTGVGNFGF
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        ANTGTGNIGIGLTGDYQTGIGGLNSGAGNLGLFNSGAGNVGFFNTGTGNF
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GNQGSGNIGIGLSGDHQVGFGGWNSGSGNVGLFNSGDGNIGFFNSGSGNF
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GLFNSGSFNTGVGNSGTGSTGLFNAGSFNTGVANAGSYNTGSFNVGDTNT
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GIANSGSFNTGIANAGLTNTGWFNSGLANTGWGNAGAYNSGGFNAGAYNT
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        GGFNPGSINTGWLNAGNANTGVANAGNVNTGAFVTGNFSNGILWRGDYQG
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               GSFNPGHVNTGWFNTGDINTGLGNSGNINTGAFVSGDMNNGFFWRGTGQG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        LAGFAVGYTLPLFPAVGADVSGGIGPITVLPPIHIPPIPVGFAAVGGIGP
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               LIGADYTITIPQIPLT----------------------------IGGGGI
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        IAIPDISVPSIHLGLDPAVHVGSITVNPITVRTPPVLVSYSQGAVTSTSG
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               LNIPITGAITGLTVQSFTVHGVGSAATPIPVNLHLNVDGESGGATVSVHI
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        PTSEIWVKPSFFPGIRIAPSSGGGATSTQGAYFVGPISIPSGTVTFPGFT
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               PN----------------------------------------------TD
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        IPLDPIDIGLPVSLTIPGFTIPGGTLIPTLPLGLALSNGIPPVDIPAIVL
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               VSFDVHVDGLPITLDLPLDSEVRPIVVPDIPISRIP-------IVLSLGS
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        DRILLDLHADTTIGPINVPIAGFGGAPGFGNSTTLPSSGFFNTGAGGGSG
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               DSTSLNTAIGAGIGPISIPILDLPTAPGFGNATDSPSSGFFNSGPGGVSG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
Rv3350c|M.tuberculosis_H37Rv        FSNTGAGMSGLLNAMSDPLLGSASGFANFG-TQLSGILNRGAGISGVYNT
Mb3380c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MMAR_4621|M.marinum_M               FGNVGDTLSGVWNFG-----SYASGLQNYGGSLLSGITNLGGATSGVGNT
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          -------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       -------------------------------
MAB_0669|M.abscessus_ATCC_1997      -------------------------------
TH_3113|M.thermoresistible__bu      -------------------------------
MLBr_01182|M.leprae_Br4923          -------------------------------
Rv3350c|M.tuberculosis_H37Rv        GALGVVTAAVVSGFGNVGQQLSGLLFTGVGP
Mb3380c|M.bovis_AF2122/97           -------------------------------
MAV_4704|M.avium_104                -------------------------------
MMAR_4621|M.marinum_M               SDLGLAIAGVISGIGNVGSQLSGLFLEGSVP
MUL_0782|M.ulcerans_Agy99           -------------------------------
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------