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ARSQEPSRGLLDPVAKMLRLPFGTPDFIEKIVTGSVNQVGRRTLYVLITTWDAAGGGPFAASAIATTGLA KTAEIVQSMFIGPVFNPLLKMLGADKIAIRASLCAAQLVGLGIMRYGVRSEPLHSMSVEMLVDAIGPTMQ RYLVGDIGRG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0258c | - | - | 100% (151) | hypothetical protein Rv0258c |
| M. tuberculosis H37Rv | Rv1685c | - | 3e-09 | 30.71% (140) | hypothetical protein Rv1685c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0264c | - | 4e-82 | 100.00% (151) | hypothetical protein Mb0264c |
| M. gilvum PYR-GCK | Mflv_0253 | - | 7e-07 | 25.62% (121) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2351c | - | 6e-07 | 24.48% (143) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0518 | - | 7e-75 | 88.08% (151) | hypothetical protein MMAR_0518 |
| M. avium 104 | MAV_4902 | - | 4e-64 | 84.56% (136) | hypothetical protein MAV_4902 |
| M. smegmatis MC2 155 | MSMEG_5282 | - | 1e-12 | 35.00% (120) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3542 | - | 2e-10 | 29.84% (124) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1181 | - | 5e-75 | 88.08% (151) | hypothetical protein MUL_1181 |
| M. vanbaalenii PYR-1 | Mvan_3298 | - | 3e-11 | 28.68% (136) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0258c|M.tuberculosis_H37Rv --------------------------MARSQEPSRGLLDPVAKMLRLPFG
Mb0264c|M.bovis_AF2122/97 --------------------------MARSQEPSRGLLDPVAKMLRLPFG
MMAR_0518|M.marinum_M --------------------------MANNEEPSRGLLDPVAKMLRLPFG
MUL_1181|M.ulcerans_Agy99 --------------------------MANNEEPSRGLLDPVAKMLRLPFG
MAV_4902|M.avium_104 ----------------------------------------MAKMLRLPFG
Mflv_0253|M.gilvum_PYR-GCK MPPPAQTGRRRGRRKGDPVSRETVLAAAKGRFARDGFEKTTLRAIAEDAG
TH_3542|M.thermoresistible__bu -----------------------VLAAAKRRFAQDGYEKTTLRAIARDAH
MAB_2351c|M.abscessus_ATCC_199 -MSS----KRPGRRPGTSSARDDILASARKLFSLNGIDKTSIRAIASDAG
Mvan_3298|M.vanbaalenii_PYR-1 -MTTNADRKRPGRPPGTSDTRDRILECARELFARNGITNTSIRSIAAGAG
MSMEG_5282|M.smegmatis_MC2_155 -MVKRSARATPGPRDDRGVLAARILAAARETFAESGWAGTTIRAVARAAD
: :
Rv0258c|M.tuberculosis_H37Rv TPDFIEKIVTGS--------------------------VNQVGRRTLYVL
Mb0264c|M.bovis_AF2122/97 TPDFIEKIVTGS--------------------------VNQVGRRTLYVL
MMAR_0518|M.marinum_M TPEFIDKIVAGS--------------------------VNQVGRRTLYML
MUL_1181|M.ulcerans_Agy99 TPEFIDKIVAGS--------------------------VNQVGRRTLYML
MAV_4902|M.avium_104 TPEFIDRIVTGG--------------------------VNQVGRRTLRML
Mflv_0253|M.gilvum_PYR-GCK VDASMVLYLFGSKEALFRESLRLILDPGVLIEALSGG-EADIGTRMVRAY
TH_3542|M.thermoresistible__bu VDASMVLYLFGSKAELFRESLELILDPEMLVAAMTGD-DGDVGTRMVRVY
MAB_2351c|M.abscessus_ATCC_199 VDPALVHHYFGTKLDLFREVVQLPVDPSVVLQPLRDVPVDELGVTIPRLI
Mvan_3298|M.vanbaalenii_PYR-1 VDPALVHHYFGTKTQLFAAAIEIPIDPMSIIGPLKEVPVDQLGRALPSLL
MSMEG_5282|M.smegmatis_MC2_155 VDPALVYHYYGSKEGLLDAATDPPQKWLDAVVATWQAPVGDTGRAVLRLL
. : * : *
Rv0258c|M.tuberculosis_H37Rv ITTWDAAGGGP-FAASAIATTGLAKTAEIVQSMFIGPVFNPLLKMLGAD-
Mb0264c|M.bovis_AF2122/97 ITTWDAAGGGP-FAASAIATTGLAKTAEIVQSMFIGPVFNPLLKMLGAD-
MMAR_0518|M.marinum_M ITTWDAAGGGP-FAASAVASTGLAKTAEIVQSMFIGPIFNPLLKMLGAD-
MUL_1181|M.ulcerans_Agy99 ITTWDAAGGGP-FAASAVASTGLAKTAEIVQSMFIGPIFNPLLKMLGAD-
MAV_4902|M.avium_104 ITTWDAAGGGP-FAASAIASTGMAKTAEIVQGMFIGPVFGPLLRILGAD-
Mflv_0253|M.gilvum_PYR-GCK LGVWESPESAESMRTMLASATSNPDAREAFRGFIQDYVLAAVVGTLGGD-
TH_3542|M.thermoresistible__bu LQIWESPDTGPTIRAMLQSATSNTDAREAFRSFLREYLLTAVSGVLGGG-
MAB_2351c|M.abscessus_ATCC_199 IALWDS-ELGANMLAVFRSALTGADD-GLVRVFFREVLVNIIAERVDSPP
Mvan_3298|M.vanbaalenii_PYR-1 LPLWDS-ELGKGFIATLRSILAGSDV-SMVRSFLQDLIATEVGGRVDDPP
MSMEG_5282|M.smegmatis_MC2_155 LDSWADDEVGPVLRAILQTAAHEPTTHEKLRKVVERSLIGVIATMGDDE-
: * . : : : . .: .. : : .
Rv0258c|M.tuberculosis_H37Rv -KIAIRASLCAAQLVGLGIMRYGVRSEPLHSMSVEMLVDAIGPTMQRYLV
Mb0264c|M.bovis_AF2122/97 -KIAIRASLCAAQLVGLGIMRYGVRSEPLHSMSVEMLVDAIGPTMQRYLV
MMAR_0518|M.marinum_M -KIAVRASLCASQLVGLGIMRYGLRSEPMHSMSVDALVDAIGPTMQHYLV
MUL_1181|M.ulcerans_Agy99 -KIAVRASLCASQLVGLGIMRYGLRSEPMHSMSVDALVDAIGPTMQHYLV
MAV_4902|M.avium_104 -KVAVRASLCASQLVGLGIMRYGIRSEPLHSMSVDAIVDAIGPTVQRYLV
Mflv_0253|M.gilvum_PYR-GCK DRARLRAMLAASSLVGTAMMRYLMEIPPLSELATEDVIRLVAPTVTRYLT
TH_3542|M.thermoresistible__bu EQARLRAELAATGLVGTAMLRYIMRVPPLAELSTEEVVRMLAPTVNRYLT
MAB_2351c|M.abscessus_ATCC_199 GSGVLRAEFAITQMAGILVGRYIMAIEPLASLTAEQIALTVGPNIQRYLT
Mvan_3298|M.vanbaalenii_PYR-1 GSGRVRVQFVASQLVGIVMARYILELEPFKSLPVEQIVDTVAPNLQRYLT
MSMEG_5282|M.smegmatis_MC2_155 RVRRTRAGLVASQTIGFALMRYVWRIEPVASMREDEVLDAVGPTLQRYID
*. : : * : ** *. .: : : :.*.: :*:
Rv0258c|M.tuberculosis_H37Rv GDIGRG----------
Mb0264c|M.bovis_AF2122/97 GDIGRG----------
MMAR_0518|M.marinum_M GDISRG----------
MUL_1181|M.ulcerans_Agy99 GDISRG----------
MAV_4902|M.avium_104 GDITR-----------
Mflv_0253|M.gilvum_PYR-GCK APADELGLPG------
TH_3542|M.thermoresistible__bu ADADELGLPSSLTAGS
MAB_2351c|M.abscessus_ATCC_199 GALPSITP--------
Mvan_3298|M.vanbaalenii_PYR-1 GELPQFSGD-------
MSMEG_5282|M.smegmatis_MC2_155 GDIGAAGQIRTGFDTA
.