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MEGDAGAGQLNPADANKSSSTEVKAADSAESDAGADQTGPQVKAADSAESDAGELGEDACPEQALVERRP SRLRRGWLVGIAATLLALAGGLGAAGYFALRSHQESQSIAREDLAAIEAAKDCVAATQAPDAGAMSASMQ KIIECGTGDFGAQASLYTSMLVEAYQAASVHVQVTDMRAAVERNNNDGSVDVLVALRVKVSNTDSDAHEV GYRLRVRMALDEGRYKIAKLDQVTK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0175 | - | - | 100% (213) | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv1363c | - | 2e-08 | 24.15% (207) | hypothetical protein Rv1363c |
| M. tuberculosis H37Rv | Rv2390c | - | 2e-06 | 25.82% (182) | hypothetical protein Rv2390c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0181 | - | 1e-116 | 100.00% (213) | mce associated membrane protein |
| M. gilvum PYR-GCK | Mflv_0705 | - | 3e-52 | 50.00% (206) | putative MCE associated membrane protein |
| M. leprae Br4923 | MLBr_02595 | - | 7e-60 | 69.09% (165) | hypothetical protein MLBr_02595 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0418 | - | 4e-72 | 64.91% (228) | Mce associated membrane protein |
| M. avium 104 | MAV_5009 | - | 2e-62 | 61.32% (212) | hypothetical protein MAV_5009 |
| M. smegmatis MC2 155 | MSMEG_0140 | - | 3e-58 | 56.46% (209) | mce associated membrane protein |
| M. thermoresistible (build 8) | TH_0291 | - | 3e-48 | 54.12% (194) | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1068 | - | 1e-70 | 66.06% (218) | Mce associated membrane protein |
| M. vanbaalenii PYR-1 | Mvan_0140 | - | 9e-54 | 53.08% (211) | putative MCE associated membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0705|M.gilvum_PYR-GCK MEGDAGTSRLIP--EADTADE----------VVDTP---TAEASDPSPDQ
Mvan_0140|M.vanbaalenii_PYR-1 MEGDAGTSRLIPDPETDTADG----------AQDAPDEASLGAPDTPPQE
Rv0175|M.tuberculosis_H37Rv ----MKAADSAESDAGADQTG----------PQVKAADSAESDAGELGED
Mb0181|M.bovis_AF2122/97 ----MKAADSAESDAGADQTG----------PQVKAADSAESDAGELGED
MLBr_02595|M.leprae_Br4923 ------------------------------MPES---------------Q
MAV_5009|M.avium_104 MEGDAGASRLNPIDTDDDSLSPQDKDEDSTAPASTDEQTGSQGAPGVAGE
MMAR_0418|M.marinum_M ----MTTEDSAESEAAPDSTDQPEPEAAAEPEASAGSDDAAQEQAEDTEQ
MUL_1068|M.ulcerans_Agy99 MRTEATAEDSSESEAAPDSTEQPEP------EAAAGSHDAAQEQAEDTEQ
MSMEG_0140|M.smegmatis_MC2_155 MEGDAGASQLNPTDQQQEHTEP-----------------------QIEQT
TH_0291|M.thermoresistible__bu MEGDAGTRRLNRTTDADDAPG-----------ESLAGDPTDVTEPSTQTP
Mflv_0705|M.gilvum_PYR-GCK DVPADT----------RRPTRLGNGWVATICAVLLLLAGGAVAAGVLSLR
Mvan_0140|M.vanbaalenii_PYR-1 QPPAEP----------RRPSRLGTGWVATICVVLLLLGGGGITAGYLALR
Rv0175|M.tuberculosis_H37Rv ACPEQA-------LVERRPSRLRRGWLVGIAATLLALAGGLGAAGYFALR
Mb0181|M.bovis_AF2122/97 ACPEQA-------LVERRPSRLRRGWLVGIAATLLALAGGLGAAGYFALR
MLBr_02595|M.leprae_Br4923 VAADDS-------GVTLNRSRLGRGWLTGIAVALLLAGCGIGTGGYCMLR
MAV_5009|M.avium_104 SAPDDADDAVPVAAVPRGPSRLGRGWLAAIAAVLVLCAAGIGAGGYLALR
MMAR_0418|M.marinum_M SGDGQAVEP----GVERRPSRLGRGWLVGISAVLLLAAGGIGAGGYLALR
MUL_1068|M.ulcerans_Agy99 SGDGQAVEP----GVERRPSRLGRGWLVGISAVLLLAAGGIGAGGYLALR
MSMEG_0140|M.smegmatis_MC2_155 TVEADA----------RRPSRLGRGWMATVCAALVLVAAALGVGGYLALR
TH_0291|M.thermoresistible__bu EPPAEE----------RRPSRLSGTWVAGICAALVVGAAGLAAGGYLAWR
: :** *:. :...*: . . ..* *
Mflv_0705|M.gilvum_PYR-GCK ANERAAETARSDEAALQAAKDCVAATQAPDTAAMTAAQSKILECSTGEFR
Mvan_0140|M.vanbaalenii_PYR-1 ANARAAEVARSDDAALQAAKECVAATQAPDTAAMTAAQSKILECSTGEFG
Rv0175|M.tuberculosis_H37Rv SHQESQSIAREDLAAIEAAKDCVAATQAPDAGAMSASMQKIIECGTGDFG
Mb0181|M.bovis_AF2122/97 SHQESQSIAREDLAAIEAAKDCVAATQAPDAGAMSASMQKIIECGTGDFG
MLBr_02595|M.leprae_Br4923 YHQDSQAMARNDNAALKTALDCVAATQAPDTNTMAASEQKIIDCGTDAFH
MAV_5009|M.avium_104 YHHESQVIARNNAAALKAAVDCVEATQAPDTNAMTASEQKIIDCGTDAYR
MMAR_0418|M.marinum_M SHQESQVIARNDAAALEAAKDCVAATQAPDTSAMAASEQKIIDCGTDQYR
MUL_1068|M.ulcerans_Agy99 SHQESQVIARNDAAALEAAKDCVAATQAPDTSAMAASEQKIIDCGTDQYR
MSMEG_0140|M.smegmatis_MC2_155 SHLDSNVIARDEAEAMQAAKDCVTATQAPDTAAMAAAQAKIIECATGDFG
TH_0291|M.thermoresistible__bu SHERSVDIARIEAAALEAAKDCVAATHAPDVESMATSQAKIIECSTGDFA
: : ** : *:::* :** **:***. :*::: **::*.*. :
Mflv_0705|M.gilvum_PYR-GCK VQAGLFSSIVAEAYQAANATVAVDDLRAAVERHNEDGTVNVLVAVRVRIT
Mvan_0140|M.vanbaalenii_PYR-1 VQAGLFSSVLAEAYQAADATVAVDDLRAAVERRNEDGTVNVLVAVRVRIS
Rv0175|M.tuberculosis_H37Rv AQASLYTSMLVEAYQAASVHVQVTDMRAAVERNNNDGSVDVLVALRVKVS
Mb0181|M.bovis_AF2122/97 AQASLYTSMLVEAYQAASVHVQVTDMRAAVERNNNDGSVDVLVALRVKVS
MLBr_02595|M.leprae_Br4923 AQALLYTNMLVQAYQAANVHVQVSDMRAAVERHNNDGSIDVLVALRVKLS
MAV_5009|M.avium_104 SQALLYTSMLVQAYQSANVHVQVSDVRAAVERNNPDGSIDILVALRVKVA
MMAR_0418|M.marinum_M SQAVLYSSMLVQAYQAANVHVQLTDMRAAVERNNPDGSVDVLVALRVKMS
MUL_1068|M.ulcerans_Agy99 SQAVLYSSMLVQAYQAANVHVQLTEMRAAVERNNPDGSVDVLVALRVKMS
MSMEG_0140|M.smegmatis_MC2_155 AQAVLYSGILLDAYQAANVQVQVSDMRAAVEKHNDDGSMDLLVAVRVLVT
TH_0291|M.thermoresistible__bu VQANLYSGMLVDAYRVADASVQVSDMRAAVERHHDDGVVDVLVAMRVKVT
** *::.:: :**: *.. * : ::*****:.: ** :::***:** ::
Mflv_0705|M.gilvum_PYR-GCK NAEAADQRVGYRL----------RATMAWDE-AQYRISSLEQVNS----
Mvan_0140|M.vanbaalenii_PYR-1 NSEAADQRVGYRL----------RATMAFDE-GQYRISSLDQVNS----
Rv0175|M.tuberculosis_H37Rv NTDSDAHEVGYRL----------RVRMALDE-GRYKIAKLDQVTK----
Mb0181|M.bovis_AF2122/97 NTDSDAHEVGYRL----------RVRMALDE-GRYKIAKLDQVTK----
MLBr_02595|M.leprae_Br4923 NDRAHNQETGYRL----------RVKMALAE-GQYKISKLDQVTK----
MAV_5009|M.avium_104 SDQSQN-ESGYRL----------RVKMALAE-GQYKISKLDQVTK----
MMAR_0418|M.marinum_M NDQDQNQETGYRL----------RVRMTPTE-GQYKISKLDQVAK----
MUL_1068|M.ulcerans_Agy99 NDQDQNQETGYRL----------RVRMTPTE-GQYKISKLDQVAK----
MSMEG_0140|M.smegmatis_MC2_155 NTEKANEEQGYRL----------RVKMARDEDGLYKVARLDQVTS----
TH_0291|M.thermoresistible__bu NTAAADQEHGYRLXXRRRPYLLPRFRRAHDRSATVRTPKSQITSAGRVP
. . **** * : . . : . : .