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AIFGRGHGASEPGGTGEPAETPGRGRLTRSVIGWVGAVAVVVSLAGSGWCGWVLFEKHQTDVAAGQALQA ARSYVVKLATMDCERIDHNMRDILEGSTGEFKDKYGKSSAHLRQLLADNRVATHGTVVAASVKSATTNKV VVLMFIDQSVSNRNSPTPQIDRSRIKVIMDKVNGRWLASKVELL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2390c | - | - | 100% (185) | hypothetical protein Rv2390c |
| M. tuberculosis H37Rv | Rv1363c | - | 2e-14 | 27.61% (163) | hypothetical protein Rv1363c |
| M. tuberculosis H37Rv | Rv1362c | - | 1e-12 | 26.97% (152) | hypothetical protein Rv1362c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2411c | - | 1e-103 | 99.46% (185) | hypothetical protein Mb2411c |
| M. gilvum PYR-GCK | Mflv_0004 | - | 5e-38 | 45.25% (179) | hypothetical protein Mflv_0004 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1004c | - | 5e-36 | 46.05% (152) | hypothetical protein MAB_1004c |
| M. marinum M | MMAR_3870 | - | 8e-40 | 54.23% (142) | hypothetical protein MMAR_3870 |
| M. avium 104 | MAV_0098 | - | 4e-48 | 54.71% (170) | hypothetical protein MAV_0098 |
| M. smegmatis MC2 155 | MSMEG_1149 | - | 3e-39 | 45.81% (179) | hypothetical protein MSMEG_1149 |
| M. thermoresistible (build 8) | TH_0161 | - | 3e-38 | 47.59% (187) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3802 | - | 4e-39 | 53.52% (142) | hypothetical protein MUL_3802 |
| M. vanbaalenii PYR-1 | Mvan_0965 | - | 6e-40 | 44.51% (173) | hypothetical protein Mvan_0965 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2390c|M.tuberculosis_H37Rv ---------MAIFG----------RG-------------------HGASE
Mb2411c|M.bovis_AF2122/97 ---------MAIFG----------RG-------------------HGASE
MAV_0098|M.avium_104 ---------MQLMNDRKPLQTVGNRGTWLVRRFRVAAEGIADDEVAPADE
MSMEG_1149|M.smegmatis_MC2_155 ---------MKLKTDKRRDVFDEAVDDTEDAEVEALDVAESEDTATEPES
TH_0161|M.thermoresistible__bu ---------VTLTDEDR-----DRTDRDETPEPESSEQVVTETSAEEAGE
Mflv_0004|M.gilvum_PYR-GCK ---------MTVTTQST---------RDDEPDTSADDEQTPEG--AGPGD
Mvan_0965|M.vanbaalenii_PYR-1 ---------MSVTTDRD----------LDDEKTDGEEDTTSQE---EPDG
MMAR_3870|M.marinum_M MHVQRKEMIVVATTEKD------DETQSEEPAASSEDNQDTEDTSQTPDI
MUL_3802|M.ulcerans_Agy99 -------MIVVATTEKD------DETQSEEPAASSEDNQDTEDTSQTPDI
MAB_1004c|M.abscessus_ATCC_199 --------MVTMTKEDVDSTNDADTDTADDKETVDSAAETDSEIAEDAAS
: .
Rv2390c|M.tuberculosis_H37Rv P----------GGTGEP-------AETPG---RGRLTR--SVIGWVGAVA
Mb2411c|M.bovis_AF2122/97 P----------GGTGEP-------AETPG---RGRLTR--SVTGWVGAVA
MAV_0098|M.avium_104 PDVAEASPNQSEQTDKA-------AEGEGEPPRPRKRRRIKLVRAIAAGI
MSMEG_1149|M.smegmatis_MC2_155 DEVTGP-SGE-KPSDKP------SDEKPAATVTSPNQRRGVVLGVAAGIL
TH_0161|M.thermoresistible__bu TGETGE-TGETEKTGEP------GEPGPAARSRRAGWLR---VGAVTAVF
Mflv_0004|M.gilvum_PYR-GCK ADVADA-HTETEPADDD------SDPDEPMTAR--GWRRRVLLGVVALVF
Mvan_0965|M.vanbaalenii_PYR-1 TEDSAA-EDQQPEDSAS------GDPGPEAGNR--SWRRRVLAGAIAAVT
MMAR_3870|M.marinum_M EVDSVE-HAEAESADDDEDNTLLADKREKTARPNRSWARYLRRGAMPLLL
MUL_3802|M.ulcerans_Agy99 EVDSVE-HAEAESADDDEDNTLLADKREKAARPNRSWARYLRRGAMPLLL
MAB_1004c|M.abscessus_ATCC_199 TDTDAASSADSDSETAS-------SDEDGDAAKGASWVRYAALGAVAAIM
Rv2390c|M.tuberculosis_H37Rv VVVSLAGSGWCGWVLFEKHQTDVAAGQALQAARSYVVKLATMDCERIDHN
Mb2411c|M.bovis_AF2122/97 VVVSLAGSGWCGWVLFEKHQTDVAAGQALQAARSYVVKLATMDCERIDHN
MAV_0098|M.avium_104 LAAVLATAGYEGWLLFEQHQKDVAAAQALDAAKKYILALTSVDTNAIDKN
MSMEG_1149|M.smegmatis_MC2_155 VAALLGGGGFVGWQLWQTKQVIAAGNQARDAAVNYAQVLTSIDSNKVDEN
TH_0161|M.thermoresistible__bu VV-LLGLCGFLGWQVWQQRQLDRAADEARQAAVEYARILTSIDADKVDEN
Mflv_0004|M.gilvum_PYR-GCK AA-LLAVSGVLGWMTWKQHQLTQAGEQARQAAVTYAQVLTSIDSAKVDEN
Mvan_0965|M.vanbaalenii_PYR-1 IG-AVATAGYLGWLLWQQNQVSRAGEQAQAAAVQYAQILTSIDSAKVDEN
MMAR_3870|M.marinum_M AG-ALALSAFLGWQQWQQHQVKLAGQQAQQAAIAYAQVLTSIDSNNVDQN
MUL_3802|M.ulcerans_Agy99 AG-ALALSAFLDWQQWQQHQVKLAGQQAQQAAIAYAQVLTSIDSNNVDQN
MAB_1004c|M.abscessus_ATCC_199 VG-ALVFSGIFGWKVWQQHQIDAAGEQALAVAIPYTETLTSIDSNDIDES
: . .* :: .* *. :* .* * *:::* :*..
Rv2390c|M.tuberculosis_H37Rv MRDILEGSTGEFKDKYGKSSAHLRQLLADNRVATHGTVVAASVKSATTNK
Mb2411c|M.bovis_AF2122/97 MRDILEGSTGEFKDKYGKSSAHLRQLLADNRVATHGTVVAASVKSATTNK
MAV_0098|M.avium_104 FAEVLDGSTGEFKDMYTKSSAQLRQTLIDNKAAAHGNVVDAAVRSATEDK
MSMEG_1149|M.smegmatis_MC2_155 FDQVLAGATGEFKDMYSQSSMQLRQLLIENKATAHGVVVESAVQSATKNK
TH_0161|M.thermoresistible__bu FAQVLDGATGEFRDMYSASSAQLRQLLIDNKASARGVVLESAVQSAGEDE
Mflv_0004|M.gilvum_PYR-GCK FNQVLDGATGEFKDMYSESSMQLRQLLIDNKAASRGVVVESAIQSVEEGR
Mvan_0965|M.vanbaalenii_PYR-1 FDQVLDGATGEFKDMYSQSSVQLRQLLIDNKASAHGVVVDSAIQSESKDK
MMAR_3870|M.marinum_M FRQVLDGATGEFKDMYTQSSVQLRQLLIDNKASAHGVVVDSAVASETVNK
MUL_3802|M.ulcerans_Agy99 FRQVLDGATGEFKDMYTQSSVQLRQLLIDNKASAHGVVVDSAVASETVNK
MAB_1004c|M.abscessus_ATCC_199 FRKILNGATGDLKKDFTPASVQLRQLLLDNKAASHGKVVNSAIQYKSTNK
: .:* *:**:::. : :* :*** * :*:.:::* *: ::: ..
Rv2390c|M.tuberculosis_H37Rv VVVLMFIDQSVSNRNSPTPQIDRSRIKVIMDKVNGRWLASKVELL
Mb2411c|M.bovis_AF2122/97 VVVLMFIDQSVSNRNSPTPQIDRSRIKVIMDKVNGRWLASKVELL
MAV_0098|M.avium_104 VEVVLFVDQSVSNGAAPAPQLDRSRVKMTMEKVDGRWLASKVELP
MSMEG_1149|M.smegmatis_MC2_155 AVVLLFVDQSVQNTAVPDPRIDRSRIKMTMEKVDGQWKASKVELP
TH_0161|M.thermoresistible__bu VVVLLFIDQTVSNAHVPEPRIDRSRVKMTMRHVDGTWRASKVALP
Mflv_0004|M.gilvum_PYR-GCK VVVLLFVDQSVTNSAVPDPRIDRSRIKMTMEYVDGRWRAAKVELA
Mvan_0965|M.vanbaalenii_PYR-1 VVVLLFVDQSVSNTSVPDPRIDRSRVKMTMEYVDGRWRASKVELP
MMAR_3870|M.marinum_M VVVLVFVDQTVTNMAVPDPRIDRSRIKMTMEKVDGRWLASKVQLL
MUL_3802|M.ulcerans_Agy99 VVVLIFVDQTVTNMAVPDPRIDRSRIKMTMEKVDGRWLASKVQLL
MAB_1004c|M.abscessus_ATCC_199 VVLLMMVDQSITNTQRPDPRVDKSRMKITMEKIDGRWLASKLEYL
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