For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
EGDAGTSRLIPEADTADEVVDTPTAEASDPSPDQDVPADTRRPTRLGNGWVATICAVLLLLAGGAVAAGV LSLRANERAAETARSDEAALQAAKDCVAATQAPDTAAMTAAQSKILECSTGEFRVQAGLFSSIVAEAYQA ANATVAVDDLRAAVERHNEDGTVNVLVAVRVRITNAEAADQRVGYRLRATMAWDEAQYRISSLEQVNS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0705 | - | - | 100% (209) | putative MCE associated membrane protein |
| M. gilvum PYR-GCK | Mflv_2526 | - | 1e-10 | 28.63% (227) | hypothetical protein Mflv_2526 |
| M. gilvum PYR-GCK | Mflv_0703 | - | 1e-07 | 27.07% (181) | hypothetical protein Mflv_0703 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0181 | - | 2e-52 | 50.00% (206) | mce associated membrane protein |
| M. tuberculosis H37Rv | Rv0175 | - | 2e-52 | 50.00% (206) | mce associated membrane protein |
| M. leprae Br4923 | MLBr_02595 | - | 4e-44 | 49.72% (179) | hypothetical protein MLBr_02595 |
| M. abscessus ATCC 19977 | MAB_4593c | - | 4e-07 | 26.90% (197) | hypothetical protein MAB_4593c |
| M. marinum M | MMAR_0418 | - | 2e-51 | 52.02% (198) | Mce associated membrane protein |
| M. avium 104 | MAV_5009 | - | 4e-47 | 46.12% (232) | hypothetical protein MAV_5009 |
| M. smegmatis MC2 155 | MSMEG_0140 | - | 2e-54 | 52.61% (211) | mce associated membrane protein |
| M. thermoresistible (build 8) | TH_0291 | - | 5e-51 | 52.08% (192) | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1068 | - | 1e-50 | 51.52% (198) | Mce associated membrane protein |
| M. vanbaalenii PYR-1 | Mvan_0140 | - | 4e-88 | 78.97% (214) | putative MCE associated membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0705|M.gilvum_PYR-GCK MEGDAGTSRLIP--EADTADE-----------------------------
Mvan_0140|M.vanbaalenii_PYR-1 MEGDAGTSRLIPDPETDTADG-----------------------------
Mb0181|M.bovis_AF2122/97 ----MKAADSAESDAGADQTG--------------------------PQV
Rv0175|M.tuberculosis_H37Rv ----MKAADSAESDAGADQTG--------------------------PQV
MLBr_02595|M.leprae_Br4923 ----------------------------------------------MPES
MAV_5009|M.avium_104 MEGDAGASRLNPIDTDDDSLSPQDKDEDS----------------TAPAS
MMAR_0418|M.marinum_M ----MTTEDSAESEAAPDSTDQPEPEAAA----------------EPEAS
MUL_1068|M.ulcerans_Agy99 MRTEATAEDSSESEAAPDSTEQPEP----------------------EAA
MSMEG_0140|M.smegmatis_MC2_155 MEGDAGASQLNPTDQQQEHTEP----------------------------
TH_0291|M.thermoresistible__bu MEGDAGTRRLNRTTDADDAPGE----------------------------
MAB_4593c|M.abscessus_ATCC_199 MADDAADKDAKNADESAVTSDAEKAESSAPSSAAVESTAEGTTEAATAEV
Mflv_0705|M.gilvum_PYR-GCK -VVDTP---TAEASDPSPDQDVP------ADTRRPTRLG-NGWVATICAV
Mvan_0140|M.vanbaalenii_PYR-1 -AQDAPDEASLGAPDTPPQEQPP------AEPRRPSRLG-TGWVATICVV
Mb0181|M.bovis_AF2122/97 KAADSAESDAGELGEDACPEQA-------LVERRPSRLR-RGWLVGIAAT
Rv0175|M.tuberculosis_H37Rv KAADSAESDAGELGEDACPEQA-------LVERRPSRLR-RGWLVGIAAT
MLBr_02595|M.leprae_Br4923 ---------------QVAADDS-------GVTLNRSRLG-RGWLTGIAVA
MAV_5009|M.avium_104 TDEQTGSQGAPGVAGESAPDDADDAVPVAAVPRGPSRLG-RGWLAAIAAV
MMAR_0418|M.marinum_M AGSDDAAQEQAEDTEQSGDGQAVEP----GVERRPSRLG-RGWLVGISAV
MUL_1068|M.ulcerans_Agy99 AGSHDAAQEQAEDTEQSGDGQAVEP----GVERRPSRLG-RGWLVGISAV
MSMEG_0140|M.smegmatis_MC2_155 -----------QIEQTTVEADA----------RRPSRLG-RGWMATVCAA
TH_0291|M.thermoresistible__bu -SLAGDPTDVTEPSTQTPEPPAE--------ERRPSRLS-GTWVAGICAA
MAB_4593c|M.abscessus_ATCC_199 ADFDAEDSEKTKDSGAVEDSDDEDISLEPDEEENPKRIRGRHWALTAAAI
.*: * ..
Mflv_0705|M.gilvum_PYR-GCK LLLLAGGAVAAGVLSLRANERAAETARSDEAALQAAKDCVAATQAPDTAA
Mvan_0140|M.vanbaalenii_PYR-1 LLLLGGGGITAGYLALRANARAAEVARSDDAALQAAKECVAATQAPDTAA
Mb0181|M.bovis_AF2122/97 LLALAGGLGAAGYFALRSHQESQSIAREDLAAIEAAKDCVAATQAPDAGA
Rv0175|M.tuberculosis_H37Rv LLALAGGLGAAGYFALRSHQESQSIAREDLAAIEAAKDCVAATQAPDAGA
MLBr_02595|M.leprae_Br4923 LLLAGCGIGTGGYCMLRYHQDSQAMARNDNAALKTALDCVAATQAPDTNT
MAV_5009|M.avium_104 LVLCAAGIGAGGYLALRYHHESQVIARNNAAALKAAVDCVEATQAPDTNA
MMAR_0418|M.marinum_M LLLAAGGIGAGGYLALRSHQESQVIARNDAAALEAAKDCVAATQAPDTSA
MUL_1068|M.ulcerans_Agy99 LLLAAGGIGAGGYLALRSHQESQVIARNDAAALEAAKDCVAATQAPDTSA
MSMEG_0140|M.smegmatis_MC2_155 LVLVAAALGVGGYLALRSHLDSNVIARDEAEAMQAAKDCVTATQAPDTAA
TH_0291|M.thermoresistible__bu LVVGAAGLAAGGYLAWRSHERSVDIARIEAAALEAAKDCVAATHAPDVES
MAB_4593c|M.abscessus_ATCC_199 VAIAIVALAA---IIGRLYEEQRIEEQSSREALAAAQEFANVMINVDSAK
: . . * : . *: :* : . . *
Mflv_0705|M.gilvum_PYR-GCK MTAAQSKILECSTGEFRVQAGLFSSIVAEAYQAANATVAVDDLRAAVERH
Mvan_0140|M.vanbaalenii_PYR-1 MTAAQSKILECSTGEFGVQAGLFSSVLAEAYQAADATVAVDDLRAAVERR
Mb0181|M.bovis_AF2122/97 MSASMQKIIECGTGDFGAQASLYTSMLVEAYQAASVHVQVTDMRAAVERN
Rv0175|M.tuberculosis_H37Rv MSASMQKIIECGTGDFGAQASLYTSMLVEAYQAASVHVQVTDMRAAVERN
MLBr_02595|M.leprae_Br4923 MAASEQKIIDCGTDAFHAQALLYTNMLVQAYQAANVHVQVSDMRAAVERH
MAV_5009|M.avium_104 MTASEQKIIDCGTDAYRSQALLYTSMLVQAYQSANVHVQVSDVRAAVERN
MMAR_0418|M.marinum_M MAASEQKIIDCGTDQYRSQAVLYSSMLVQAYQAANVHVQLTDMRAAVERN
MUL_1068|M.ulcerans_Agy99 MAASEQKIIDCGTDQYRSQAVLYSSMLVQAYQAANVHVQLTEMRAAVERN
MSMEG_0140|M.smegmatis_MC2_155 MAAAQAKIIECATGDFGAQAVLYSGILLDAYQAANVQVQVSDMRAAVEKH
TH_0291|M.thermoresistible__bu MATSQAKIIECSTGDFAVQANLYSGMLVDAYRVADASVQVSDMRAAVERH
MAB_4593c|M.abscessus_ATCC_199 LDESSNKTLERSTGDFKQKYSESSTTLRQVMIENKAKATGVVVDSAVKSA
: : * :: .*. : : : : :. .. . : :**:
Mflv_0705|M.gilvum_PYR-GCK NEDGTVNVLVAVRVRITNAEAADQRVGYRL----------RATMAWDE-A
Mvan_0140|M.vanbaalenii_PYR-1 NEDGTVNVLVAVRVRISNSEAADQRVGYRL----------RATMAFDE-G
Mb0181|M.bovis_AF2122/97 NNDGSVDVLVALRVKVSNTDSDAHEVGYRL----------RVRMALDE-G
Rv0175|M.tuberculosis_H37Rv NNDGSVDVLVALRVKVSNTDSDAHEVGYRL----------RVRMALDE-G
MLBr_02595|M.leprae_Br4923 NNDGSIDVLVALRVKLSNDRAHNQETGYRL----------RVKMALAE-G
MAV_5009|M.avium_104 NPDGSIDILVALRVKVASDQSQN-ESGYRL----------RVKMALAE-G
MMAR_0418|M.marinum_M NPDGSVDVLVALRVKMSNDQDQNQETGYRL----------RVRMTPTE-G
MUL_1068|M.ulcerans_Agy99 NPDGSVDVLVALRVKMSNDQDQNQETGYRL----------RVRMTPTE-G
MSMEG_0140|M.smegmatis_MC2_155 NDDGSMDLLVAVRVLVTNTEKANEEQGYRL----------RVKMARDEDG
TH_0291|M.thermoresistible__bu HDDGVVDVLVAMRVKVTNTAAADQEHGYRLXXRRRPYLLPRFRRAHDRSA
MAB_4593c|M.abscessus_ATCC_199 APD-KVEVLLFIDQAVSNVAIPDARMDRSR---------VQITMQKVD-G
* :::*: : ::. . . : .
Mflv_0705|M.gilvum_PYR-GCK QYRISSLEQVNS----
Mvan_0140|M.vanbaalenii_PYR-1 QYRISSLDQVNS----
Mb0181|M.bovis_AF2122/97 RYKIAKLDQVTK----
Rv0175|M.tuberculosis_H37Rv RYKIAKLDQVTK----
MLBr_02595|M.leprae_Br4923 QYKISKLDQVTK----
MAV_5009|M.avium_104 QYKISKLDQVTK----
MMAR_0418|M.marinum_M QYKISKLDQVAK----
MUL_1068|M.ulcerans_Agy99 QYKISKLDQVAK----
MSMEG_0140|M.smegmatis_MC2_155 LYKVARLDQVTS----
TH_0291|M.thermoresistible__bu TVRTPKSQITSAGRVP
MAB_4593c|M.abscessus_ATCC_199 RWLASDVELT------
. : .