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VTTEDSAESEAAPDSTDQPEPEAAAEPEASAGSDDAAQEQAEDTEQSGDGQAVEPGVERRPSRLGRGWLV GISAVLLLAAGGIGAGGYLALRSHQESQVIARNDAAALEAAKDCVAATQAPDTSAMAASEQKIIDCGTDQ YRSQAVLYSSMLVQAYQAANVHVQLTDMRAAVERNNPDGSVDVLVALRVKMSNDQDQNQETGYRLRVRMT PTEGQYKISKLDQVAK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0418 | - | - | 100% (226) | Mce associated membrane protein |
| M. marinum M | MMAR_4702 | - | 4e-11 | 25.00% (236) | hypothetical protein MMAR_4702 |
| M. marinum M | MMAR_4687 | - | 2e-10 | 29.46% (224) | hypothetical protein MMAR_4687 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0181 | - | 3e-72 | 64.91% (228) | mce associated membrane protein |
| M. gilvum PYR-GCK | Mflv_0705 | - | 2e-51 | 52.02% (198) | putative MCE associated membrane protein |
| M. tuberculosis H37Rv | Rv0175 | - | 3e-72 | 64.91% (228) | mce associated membrane protein |
| M. leprae Br4923 | MLBr_02595 | - | 5e-69 | 73.14% (175) | hypothetical protein MLBr_02595 |
| M. abscessus ATCC 19977 | MAB_4593c | - | 1e-08 | 24.57% (232) | hypothetical protein MAB_4593c |
| M. avium 104 | MAV_5009 | - | 3e-75 | 65.93% (226) | hypothetical protein MAV_5009 |
| M. smegmatis MC2 155 | MSMEG_0140 | - | 3e-58 | 56.50% (200) | mce associated membrane protein |
| M. thermoresistible (build 8) | TH_0291 | - | 4e-47 | 53.48% (187) | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1068 | - | 1e-116 | 95.11% (225) | Mce associated membrane protein |
| M. vanbaalenii PYR-1 | Mvan_0140 | - | 9e-52 | 49.32% (221) | putative MCE associated membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0705|M.gilvum_PYR-GCK -----------------------MEGDAGTSRLIP--EADTADEVV----
Mvan_0140|M.vanbaalenii_PYR-1 -----------------------MEGDAGTSRLIPDPETDTADGAQ----
MMAR_0418|M.marinum_M ------------------------MTTEDSAESEAAPDSTDQPEPEAAAE
MUL_1068|M.ulcerans_Agy99 --------------------MRTEATAEDSSESEAAPDSTEQPEP-----
MLBr_02595|M.leprae_Br4923 -----------------------------------------MPES-----
MAV_5009|M.avium_104 -----------MEGDAGASRLNPIDTDDDSLSPQDKDEDSTAPAST----
Mb0181|M.bovis_AF2122/97 ------------------------MKAADSAESDAGADQTGPQVK-----
Rv0175|M.tuberculosis_H37Rv ------------------------MKAADSAESDAGADQTGPQVK-----
MSMEG_0140|M.smegmatis_MC2_155 ------------------------------MEGDAGASQLNPTDQ-----
TH_0291|M.thermoresistible__bu -----------------------MEGDAGTRRLNRTTDADDAPGE-----
MAB_4593c|M.abscessus_ATCC_199 MADDAADKDAKNADESAVTSDAEKAESSAPSSAAVESTAEGTTEAATAEV
Mflv_0705|M.gilvum_PYR-GCK ---------DTP---TAEASDPSPDQDVPADTRRPTRLG-NGWVATICAV
Mvan_0140|M.vanbaalenii_PYR-1 ---------DAPDEASLGAPDTPPQEQPPAEPRRPSRLG-TGWVATICVV
MMAR_0418|M.marinum_M PEASAGSDDAAQEQAEDTEQSGDGQAVEPGVERRPSRLG-RGWLVGISAV
MUL_1068|M.ulcerans_Agy99 -EAAAGSHDAAQEQAEDTEQSGDGQAVEPGVERRPSRLG-RGWLVGISAV
MLBr_02595|M.leprae_Br4923 ---------------QVAADDS-------GVTLNRSRLG-RGWLTGIAVA
MAV_5009|M.avium_104 -DEQTGSQGAPGVAGESAPDDADDAVPVAAVPRGPSRLG-RGWLAAIAAV
Mb0181|M.bovis_AF2122/97 --------AADSAESDAGELGEDACPEQALVERRPSRLR-RGWLVGIAAT
Rv0175|M.tuberculosis_H37Rv --------AADSAESDAGELGEDACPEQALVERRPSRLR-RGWLVGIAAT
MSMEG_0140|M.smegmatis_MC2_155 --------------QQEHTEPQIEQTTVEADARRPSRLG-RGWMATVCAA
TH_0291|M.thermoresistible__bu ---------SLAGDPTDVTEPSTQTPEPPAEERRPSRLS-GTWVAGICAA
MAB_4593c|M.abscessus_ATCC_199 ADFDAEDSEKTKDSGAVEDSDDEDISLEPDEEENPKRIRGRHWALTAAAI
.*: * ..
Mflv_0705|M.gilvum_PYR-GCK LLLLAGGAVAAGVLSLRANERAAETARSDEAALQAAKDCVAATQAPDTAA
Mvan_0140|M.vanbaalenii_PYR-1 LLLLGGGGITAGYLALRANARAAEVARSDDAALQAAKECVAATQAPDTAA
MMAR_0418|M.marinum_M LLLAAGGIGAGGYLALRSHQESQVIARNDAAALEAAKDCVAATQAPDTSA
MUL_1068|M.ulcerans_Agy99 LLLAAGGIGAGGYLALRSHQESQVIARNDAAALEAAKDCVAATQAPDTSA
MLBr_02595|M.leprae_Br4923 LLLAGCGIGTGGYCMLRYHQDSQAMARNDNAALKTALDCVAATQAPDTNT
MAV_5009|M.avium_104 LVLCAAGIGAGGYLALRYHHESQVIARNNAAALKAAVDCVEATQAPDTNA
Mb0181|M.bovis_AF2122/97 LLALAGGLGAAGYFALRSHQESQSIAREDLAAIEAAKDCVAATQAPDAGA
Rv0175|M.tuberculosis_H37Rv LLALAGGLGAAGYFALRSHQESQSIAREDLAAIEAAKDCVAATQAPDAGA
MSMEG_0140|M.smegmatis_MC2_155 LVLVAAALGVGGYLALRSHLDSNVIARDEAEAMQAAKDCVTATQAPDTAA
TH_0291|M.thermoresistible__bu LVVGAAGLAAGGYLAWRSHERSVDIARIEAAALEAAKDCVAATHAPDVES
MAB_4593c|M.abscessus_ATCC_199 VAIAIVALAA---IIGRLYEEQRIEEQSSREALAAAQEFANVMINVDSAK
: . . * : . *: :* : . . *
Mflv_0705|M.gilvum_PYR-GCK MTAAQSKILECSTGEFRVQAGLFSSIVAEAYQAANATVAVDDLRAAVERH
Mvan_0140|M.vanbaalenii_PYR-1 MTAAQSKILECSTGEFGVQAGLFSSVLAEAYQAADATVAVDDLRAAVERR
MMAR_0418|M.marinum_M MAASEQKIIDCGTDQYRSQAVLYSSMLVQAYQAANVHVQLTDMRAAVERN
MUL_1068|M.ulcerans_Agy99 MAASEQKIIDCGTDQYRSQAVLYSSMLVQAYQAANVHVQLTEMRAAVERN
MLBr_02595|M.leprae_Br4923 MAASEQKIIDCGTDAFHAQALLYTNMLVQAYQAANVHVQVSDMRAAVERH
MAV_5009|M.avium_104 MTASEQKIIDCGTDAYRSQALLYTSMLVQAYQSANVHVQVSDVRAAVERN
Mb0181|M.bovis_AF2122/97 MSASMQKIIECGTGDFGAQASLYTSMLVEAYQAASVHVQVTDMRAAVERN
Rv0175|M.tuberculosis_H37Rv MSASMQKIIECGTGDFGAQASLYTSMLVEAYQAASVHVQVTDMRAAVERN
MSMEG_0140|M.smegmatis_MC2_155 MAAAQAKIIECATGDFGAQAVLYSGILLDAYQAANVQVQVSDMRAAVEKH
TH_0291|M.thermoresistible__bu MATSQAKIIECSTGDFAVQANLYSGMLVDAYRVADASVQVSDMRAAVERH
MAB_4593c|M.abscessus_ATCC_199 LDESSNKTLERSTGDFKQKYSESSTTLRQVMIENKAKATGVVVDSAVKSA
: : * :: .*. : : : : :. .. . : :**:
Mflv_0705|M.gilvum_PYR-GCK NEDGTVNVLVAVRVRITNAEAADQRVGYRL----------RATMAWDE-A
Mvan_0140|M.vanbaalenii_PYR-1 NEDGTVNVLVAVRVRISNSEAADQRVGYRL----------RATMAFDE-G
MMAR_0418|M.marinum_M NPDGSVDVLVALRVKMSNDQDQNQETGYRL----------RVRMTPTE-G
MUL_1068|M.ulcerans_Agy99 NPDGSVDVLVALRVKMSNDQDQNQETGYRL----------RVRMTPTE-G
MLBr_02595|M.leprae_Br4923 NNDGSIDVLVALRVKLSNDRAHNQETGYRL----------RVKMALAE-G
MAV_5009|M.avium_104 NPDGSIDILVALRVKVASDQSQN-ESGYRL----------RVKMALAE-G
Mb0181|M.bovis_AF2122/97 NNDGSVDVLVALRVKVSNTDSDAHEVGYRL----------RVRMALDE-G
Rv0175|M.tuberculosis_H37Rv NNDGSVDVLVALRVKVSNTDSDAHEVGYRL----------RVRMALDE-G
MSMEG_0140|M.smegmatis_MC2_155 NDDGSMDLLVAVRVLVTNTEKANEEQGYRL----------RVKMARDEDG
TH_0291|M.thermoresistible__bu HDDGVVDVLVAMRVKVTNTAAADQEHGYRLXXRRRPYLLPRFRRAHDRSA
MAB_4593c|M.abscessus_ATCC_199 APD-KVEVLLFIDQAVSNVAIPDARMDRSR---------VQITMQKVD-G
* :::*: : ::. . . : .
Mflv_0705|M.gilvum_PYR-GCK QYRISSLEQVNS----
Mvan_0140|M.vanbaalenii_PYR-1 QYRISSLDQVNS----
MMAR_0418|M.marinum_M QYKISKLDQVAK----
MUL_1068|M.ulcerans_Agy99 QYKISKLDQVAK----
MLBr_02595|M.leprae_Br4923 QYKISKLDQVTK----
MAV_5009|M.avium_104 QYKISKLDQVTK----
Mb0181|M.bovis_AF2122/97 RYKIAKLDQVTK----
Rv0175|M.tuberculosis_H37Rv RYKIAKLDQVTK----
MSMEG_0140|M.smegmatis_MC2_155 LYKVARLDQVTS----
TH_0291|M.thermoresistible__bu TVRTPKSQITSAGRVP
MAB_4593c|M.abscessus_ATCC_199 RWLASDVELT------
. : .