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M. leprae Br4923 MLBr_02595 (-)

annotation: hypothetical protein MLBr_02595
coordinates: 3100677 - 3101225
length: 182

LPESQVAADDSGVTLNRSRLGRGWLTGIAVALLLAGCGIGTGGYCMLRYHQDSQAMARNDNAALKTALDC
VAATQAPDTNTMAASEQKIIDCGTDAFHAQALLYTNMLVQAYQAANVHVQVSDMRAAVERHNNDGSIDVL
VALRVKLSNDRAHNQETGYRLRVKMALAEGQYKISKLDQVTK
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02595--100% (182)hypothetical protein MLBr_02595

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0181-1e-5969.09% (165) mce associated membrane protein
M. gilvum PYR-GCKMflv_0705-1e-4349.72% (179) putative MCE associated membrane protein
M. tuberculosis H37RvRv0175-1e-5969.09% (165) mce associated membrane protein
M. abscessus ATCC 19977-----
M. marinum MMMAR_0418-1e-6873.14% (175) Mce associated membrane protein
M. avium 104MAV_5009-3e-6872.63% (179) hypothetical protein MAV_5009
M. smegmatis MC2 155MSMEG_0140-3e-5159.39% (165) mce associated membrane protein
M. thermoresistible (build 8)TH_0291-1e-3955.56% (144) PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN
M. ulcerans Agy99MUL_1068-3e-6872.57% (175) Mce associated membrane protein
M. vanbaalenii PYR-1Mvan_0140-3e-4555.21% (163) putative MCE associated membrane protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0705|M.gilvum_PYR-GCK          MEGDAGTSRLIP--EADTADE----------VVDTP---TAEASDPSPDQ
Mvan_0140|M.vanbaalenii_PYR-1       MEGDAGTSRLIPDPETDTADG----------AQDAPDEASLGAPDTPPQE
Mb0181|M.bovis_AF2122/97            ----MKAADSAESDAGADQTG----------PQVKAADSAESDAGELGED
Rv0175|M.tuberculosis_H37Rv         ----MKAADSAESDAGADQTG----------PQVKAADSAESDAGELGED
MLBr_02595|M.leprae_Br4923          ------------------------------MPES---------------Q
MAV_5009|M.avium_104                MEGDAGASRLNPIDTDDDSLSPQDKDEDSTAPASTDEQTGSQGAPGVAGE
MMAR_0418|M.marinum_M               ----MTTEDSAESEAAPDSTDQPEPEAAAEPEASAGSDDAAQEQAEDTEQ
MUL_1068|M.ulcerans_Agy99           MRTEATAEDSSESEAAPDSTEQPEP------EAAAGSHDAAQEQAEDTEQ
MSMEG_0140|M.smegmatis_MC2_155      MEGDAGASQLNPTDQQQEHTEP-----------------------QIEQT
TH_0291|M.thermoresistible__bu      MEGDAGTRRLNRTTDADDAPG-----------ESLAGDPTDVTEPSTQTP
                                                                                      

Mflv_0705|M.gilvum_PYR-GCK          DVPADT----------RRPTRLGNGWVATICAVLLLLAGGAVAAGVLSLR
Mvan_0140|M.vanbaalenii_PYR-1       QPPAEP----------RRPSRLGTGWVATICVVLLLLGGGGITAGYLALR
Mb0181|M.bovis_AF2122/97            ACPEQA-------LVERRPSRLRRGWLVGIAATLLALAGGLGAAGYFALR
Rv0175|M.tuberculosis_H37Rv         ACPEQA-------LVERRPSRLRRGWLVGIAATLLALAGGLGAAGYFALR
MLBr_02595|M.leprae_Br4923          VAADDS-------GVTLNRSRLGRGWLTGIAVALLLAGCGIGTGGYCMLR
MAV_5009|M.avium_104                SAPDDADDAVPVAAVPRGPSRLGRGWLAAIAAVLVLCAAGIGAGGYLALR
MMAR_0418|M.marinum_M               SGDGQAVEP----GVERRPSRLGRGWLVGISAVLLLAAGGIGAGGYLALR
MUL_1068|M.ulcerans_Agy99           SGDGQAVEP----GVERRPSRLGRGWLVGISAVLLLAAGGIGAGGYLALR
MSMEG_0140|M.smegmatis_MC2_155      TVEADA----------RRPSRLGRGWMATVCAALVLVAAALGVGGYLALR
TH_0291|M.thermoresistible__bu      EPPAEE----------RRPSRLSGTWVAGICAALVVGAAGLAAGGYLAWR
                                        :              :**   *:. :...*:  . .  ..*    *

Mflv_0705|M.gilvum_PYR-GCK          ANERAAETARSDEAALQAAKDCVAATQAPDTAAMTAAQSKILECSTGEFR
Mvan_0140|M.vanbaalenii_PYR-1       ANARAAEVARSDDAALQAAKECVAATQAPDTAAMTAAQSKILECSTGEFG
Mb0181|M.bovis_AF2122/97            SHQESQSIAREDLAAIEAAKDCVAATQAPDAGAMSASMQKIIECGTGDFG
Rv0175|M.tuberculosis_H37Rv         SHQESQSIAREDLAAIEAAKDCVAATQAPDAGAMSASMQKIIECGTGDFG
MLBr_02595|M.leprae_Br4923          YHQDSQAMARNDNAALKTALDCVAATQAPDTNTMAASEQKIIDCGTDAFH
MAV_5009|M.avium_104                YHHESQVIARNNAAALKAAVDCVEATQAPDTNAMTASEQKIIDCGTDAYR
MMAR_0418|M.marinum_M               SHQESQVIARNDAAALEAAKDCVAATQAPDTSAMAASEQKIIDCGTDQYR
MUL_1068|M.ulcerans_Agy99           SHQESQVIARNDAAALEAAKDCVAATQAPDTSAMAASEQKIIDCGTDQYR
MSMEG_0140|M.smegmatis_MC2_155      SHLDSNVIARDEAEAMQAAKDCVTATQAPDTAAMAAAQAKIIECATGDFG
TH_0291|M.thermoresistible__bu      SHERSVDIARIEAAALEAAKDCVAATHAPDVESMATSQAKIIECSTGDFA
                                     :  :   ** :  *:::* :** **:***. :*:::  **::*.*. : 

Mflv_0705|M.gilvum_PYR-GCK          VQAGLFSSIVAEAYQAANATVAVDDLRAAVERHNEDGTVNVLVAVRVRIT
Mvan_0140|M.vanbaalenii_PYR-1       VQAGLFSSVLAEAYQAADATVAVDDLRAAVERRNEDGTVNVLVAVRVRIS
Mb0181|M.bovis_AF2122/97            AQASLYTSMLVEAYQAASVHVQVTDMRAAVERNNNDGSVDVLVALRVKVS
Rv0175|M.tuberculosis_H37Rv         AQASLYTSMLVEAYQAASVHVQVTDMRAAVERNNNDGSVDVLVALRVKVS
MLBr_02595|M.leprae_Br4923          AQALLYTNMLVQAYQAANVHVQVSDMRAAVERHNNDGSIDVLVALRVKLS
MAV_5009|M.avium_104                SQALLYTSMLVQAYQSANVHVQVSDVRAAVERNNPDGSIDILVALRVKVA
MMAR_0418|M.marinum_M               SQAVLYSSMLVQAYQAANVHVQLTDMRAAVERNNPDGSVDVLVALRVKMS
MUL_1068|M.ulcerans_Agy99           SQAVLYSSMLVQAYQAANVHVQLTEMRAAVERNNPDGSVDVLVALRVKMS
MSMEG_0140|M.smegmatis_MC2_155      AQAVLYSGILLDAYQAANVQVQVSDMRAAVEKHNDDGSMDLLVAVRVLVT
TH_0291|M.thermoresistible__bu      VQANLYSGMLVDAYRVADASVQVSDMRAAVERHHDDGVVDVLVAMRVKVT
                                     ** *::.:: :**: *.. * : ::*****:.: ** :::***:** ::

Mflv_0705|M.gilvum_PYR-GCK          NAEAADQRVGYRL----------RATMAWDE-AQYRISSLEQVNS----
Mvan_0140|M.vanbaalenii_PYR-1       NSEAADQRVGYRL----------RATMAFDE-GQYRISSLDQVNS----
Mb0181|M.bovis_AF2122/97            NTDSDAHEVGYRL----------RVRMALDE-GRYKIAKLDQVTK----
Rv0175|M.tuberculosis_H37Rv         NTDSDAHEVGYRL----------RVRMALDE-GRYKIAKLDQVTK----
MLBr_02595|M.leprae_Br4923          NDRAHNQETGYRL----------RVKMALAE-GQYKISKLDQVTK----
MAV_5009|M.avium_104                SDQSQN-ESGYRL----------RVKMALAE-GQYKISKLDQVTK----
MMAR_0418|M.marinum_M               NDQDQNQETGYRL----------RVRMTPTE-GQYKISKLDQVAK----
MUL_1068|M.ulcerans_Agy99           NDQDQNQETGYRL----------RVRMTPTE-GQYKISKLDQVAK----
MSMEG_0140|M.smegmatis_MC2_155      NTEKANEEQGYRL----------RVKMARDEDGLYKVARLDQVTS----
TH_0291|M.thermoresistible__bu      NTAAADQEHGYRLXXRRRPYLLPRFRRAHDRSATVRTPKSQITSAGRVP
                                    .      . ****          *   :  . .  : .  : .