For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AETTEPPSDAGTSQADAMALAAEAEAAEAEALAAAARARARAARLKREALAMAPAEDENVPEEYADWEDA EDYDDYDDYEAADQEAARSASWRRRLRVRLPRLSTIAMAAAVVIICGFTGLSGYIVWQHHEATERQQRAA AFAAGAKQGVINMTSLDFNKAKEDVARVIDSSTGEFRDDFQQRAADFTKVVEQSKVVTEGTVNATAVESM NEHSAVVLVAATSRVTNSAGAKDEPRAWRLKVTVTEEGGQYKMSKVEFVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1363c | - | - | 100% (261) | POSSIBLE MEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv1972 | - | 1e-23 | 31.79% (195) | mce associated membrane protein |
| M. tuberculosis H37Rv | Rv2390c | - | 4e-14 | 27.61% (163) | hypothetical protein Rv2390c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1398c | - | 1e-144 | 99.62% (261) | hypothetical protein Mb1398c |
| M. gilvum PYR-GCK | Mflv_2526 | - | 2e-60 | 48.74% (277) | hypothetical protein Mflv_2526 |
| M. leprae Br4923 | MLBr_02597 | - | 2e-07 | 29.81% (161) | hypothetical protein MLBr_02597 |
| M. abscessus ATCC 19977 | MAB_1004c | - | 7e-17 | 26.27% (217) | hypothetical protein MAB_1004c |
| M. marinum M | MMAR_3994 | - | 2e-91 | 66.06% (274) | hypothetical protein MMAR_3994 |
| M. avium 104 | MAV_0938 | - | 2e-84 | 58.45% (296) | hypothetical protein MAV_0938 |
| M. smegmatis MC2 155 | MSMEG_4771 | - | 3e-62 | 51.44% (278) | hypothetical protein MSMEG_4771 |
| M. thermoresistible (build 8) | TH_0392 | - | 3e-51 | 56.98% (172) | POSSIBLE MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_3858 | - | 7e-91 | 65.45% (275) | hypothetical protein MUL_3858 |
| M. vanbaalenii PYR-1 | Mvan_4132 | - | 3e-63 | 51.22% (287) | hypothetical protein Mvan_4132 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1363c|M.tuberculosis_H37Rv MAETTEPP------------------SDAGTSQADAMALA--AEAEAAEA
Mb1398c|M.bovis_AF2122/97 MAETTEPP------------------SDAGTSQADAMALA--AEAEAAEA
MMAR_3994|M.marinum_M MAETNEPS------------------SELPTTKANAMALAAEAEAEAAEA
MUL_3858|M.ulcerans_Agy99 MAETNEPS------------------SELPTTKANAMALAAEAEAEAAEA
MAV_0938|M.avium_104 MADAKKPP------------------HDSATSDEDVKALLEEAEAEAAEA
Mflv_2526|M.gilvum_PYR-GCK MPSFRRRDSVIEADRVEESTVD----PEGVPAGDRARALADVAEAEAAEA
Mvan_4132|M.vanbaalenii_PYR-1 MPSFRRRDAVIDADRVEESTVE----PESVTEADQARALAEEAEAEAAEA
TH_0392|M.thermoresistible__bu --------------------------------------------------
MSMEG_4771|M.smegmatis_MC2_155 MPSRKPTLPVINGSHGDDQDADRSDSPAGELSADDALLLAEQAEAEAAEA
MAB_1004c|M.abscessus_ATCC_199 ---------------------------MVTMTKEDVDSTNDADTDTADDK
MLBr_02597|M.leprae_Br4923 --------------------------------------------------
Rv1363c|M.tuberculosis_H37Rv EALAAAARARARAARLKREALAMAPAE--DENVPEEYADWEDAEDYDDY-
Mb1398c|M.bovis_AF2122/97 EALAAAARARARAARLKREALAMAPAE--DENVPEEYADWEDAEDYDDY-
MMAR_3994|M.marinum_M EALAAAARARARAAQLKREALALAEDEEYDEYEDDEYEDDEEYEDYDDYV
MUL_3858|M.ulcerans_Agy99 EALAAAARARARAAQLKREALALAEDEEYDEYEDD-----EEYEDYDDYV
MAV_0938|M.avium_104 EALAAAARARARAARLRREAQAQAAKAAAETSEADEHAADDEPAETDDEV
Mflv_2526|M.gilvum_PYR-GCK EAMAAAARARARAAKLRQEALAAAADSDGETARTDAVASTTEATDDAD--
Mvan_4132|M.vanbaalenii_PYR-1 EAMAAAAKARARAARLRRQALAADVAAKPEVGEDSATVGDADVDGDDDAV
TH_0392|M.thermoresistible__bu -------------VHWRPXXXAAPDSS-----------------------
MSMEG_4771|M.smegmatis_MC2_155 EAIAAAARARAEALRLRRQAEEAAKRSSEADAENESVDESETGEPEDAEN
MAB_1004c|M.abscessus_ATCC_199 ETVDSAAETDSEIAEDAASTDTDAASSADSDSETAS--------------
MLBr_02597|M.leprae_Br4923 --MSPRRKFQAGEGLLLVSHTVASQRR-----------------------
Rv1363c|M.tuberculosis_H37Rv ----------------DDYEAADQEAARSAS----------------WRR
Mb1398c|M.bovis_AF2122/97 ----------------DDYEAADQEAARSAS----------------WRR
MMAR_3994|M.marinum_M AE----------DEDAESTEAEDEEPNKPLS----------------WRD
MUL_3858|M.ulcerans_Agy99 AE----------DEDAESTEAEDEEPNKPLS----------------WRD
MAV_0938|M.avium_104 SDS----VEATDADDTETTQAQTKEAAKEAEPNEEAAEETAEDAESESKA
Mflv_2526|M.gilvum_PYR-GCK ------DAELLDID-DDRDDDLDGDETDAVGEA--------------ESP
Mvan_4132|M.vanbaalenii_PYR-1 TGSADAEPEVVDIETAETDETAETDDSAPADGG--------------AAP
TH_0392|M.thermoresistible__bu ------------------------DTTPAAG-------------------
MSMEG_4771|M.smegmatis_MC2_155 AEDTEDTEAAEDTEAAEKDSAGKPEAQEAQELP--------------EAK
MAB_1004c|M.abscessus_ATCC_199 -------------------SDEDGDAAKGAS-------------------
MLBr_02597|M.leprae_Br4923 --------------------------------------------------
Rv1363c|M.tuberculosis_H37Rv RLR--VRLPRLS----TIAMAAAVVIICGFTGLSGYIVWQHHEATERQQR
Mb1398c|M.bovis_AF2122/97 RLR--VRLPRLS----TIAMAAAVVIICGFTGLSGYIVWQHHEATERQQR
MMAR_3994|M.marinum_M RAVKWARIARLS----IVVKVAALLIVFGFAGLSAYFVWNHSQVTQRQER
MUL_3858|M.ulcerans_Agy99 RAVKWARIARLS----IVVKVAALLIVFGFAGLSAYFVWNHGQVTQRQER
MAV_0938|M.avium_104 RSRRRLRLPSWS----VAWKAAVIALICAFVAASGYMMWERHQTSERNQR
Mflv_2526|M.gilvum_PYR-GCK TRKRLLRRPGWASVGVALVLVIAVLGTAALLAVSGYMRLEHRDAENLRQQ
Mvan_4132|M.vanbaalenii_PYR-1 SRRRRIPRPGWK----AAVATVVALATVALLGASGYMVWTHRGAEKLRQQ
TH_0392|M.thermoresistible__bu ARRRFRLR--WG----IVARAAAIVAICLLLAASGYMVWYHQQVEAEKQR
MSMEG_4771|M.smegmatis_MC2_155 LTTR-TNAPVWK----WIAAGVTVVIILGLLTVSGLMMYHHKQMQDDQRR
MAB_1004c|M.abscessus_ATCC_199 ----WVRYAALG------AVAAIMVGALVFSGIFGWKVWQQHQIDAAGEQ
MLBr_02597|M.leprae_Br4923 ----------WG---LPLAATFAALVMVAAITASTLMSISHASRELAVAK
: :
Rv1363c|M.tuberculosis_H37Rv AAAFAAGAKQGVINMTSLDFNKAKEDVARVIDSSTGEFRDDFQQRAADFT
Mb1398c|M.bovis_AF2122/97 AAAFAAGAKQGVINMNSLDFNKAKEDVARVIDSSTGEFRDDFQQRAADFT
MMAR_3994|M.marinum_M AEAFTDGAKTGVVNMTSLDFNKAKEDVQRVIDSSTGEFKEEFQSRAADFT
MUL_3858|M.ulcerans_Agy99 AEAFTDGAKTGVVNMISLDFNRAKEDVQRVIDSSTGEFKEEFHSRAADFT
MAV_0938|M.avium_104 IANFLAAARQGVVNMTSLDFNKAKEDVQRVIDSSTGQFRDDFQQRAKDFT
Mflv_2526|M.gilvum_PYR-GCK NAEYAAAARQSVVTLMSLDFNKAEEDVQRIIDNSTGQFKDDFESQAAEFV
Mvan_4132|M.vanbaalenii_PYR-1 NAEYAAAARQSVVTLMSLDFNKAEEDVQRIIDNSTGQFKTDFESQAADFV
TH_0392|M.thermoresistible__bu AAEFAAAARQGIVSLMSLDFNRAEEDVQRIIDNSTGEFREEFESAAEDFA
MSMEG_4771|M.smegmatis_MC2_155 AAEFAAAARQGVVTLMSLDHTHAKEDVQRIIDMSTGDFRADFEATAEDFA
MAB_1004c|M.abscessus_ATCC_199 ALAVAIPYTE---TLTSIDSNDIDESFRKILNGATGDLKKDFTPASVQLR
MLBr_02597|M.leprae_Br4923 DQQVLSYVKWFMTQFTTLDPYHANDYVARILAQATGDFAKQYNEKVNEIL
: ::* .: . ::: :**:: :: ::
Rv1363c|M.tuberculosis_H37Rv KVVEQSKVVTEGTVNATAVESMNEHSAVVLVAATSRVTNSAGAKDEPRAW
Mb1398c|M.bovis_AF2122/97 KVVEQSKVVTEGTVNATAVESMNEHSAVVLVAATSRVTNSAGAKDEPRAW
MMAR_3994|M.marinum_M KVVEQSKVVTEGTVHAAAVESMEGHTAVVLISATSHVTNGGDGKQEPRIW
MUL_3858|M.ulcerans_Agy99 KVVEQSKVVTEGTVHAAAVESMEGHTAVVLISATSRVTNGGDGKQEPRIW
MAV_0938|M.avium_104 TVVEQSKVVTQGTVNAAAVQSIDGNSALVLVAATSRITNAAGAKDEPRNW
Mflv_2526|M.gilvum_PYR-GCK KVAQDSKVVTEVTVNSTAVERMTGDGAEVLVAASSRVTNTAGADQEPRTW
Mvan_4132|M.vanbaalenii_PYR-1 KVAQDSKVVTEVSVNSTAVESMSDDSAEVLVAASSRVTNTAGANQEPRTW
TH_0392|M.thermoresistible__bu TVAKESKVITDVSVNATAVQSMTEDSAEVLVAATSSITNEAGANQDPRSW
MSMEG_4771|M.smegmatis_MC2_155 KVAEQAKVTTEAQVNATAVDSMTDDSAVVLVAATSRISNSAGADQDPRNW
MAB_1004c|M.abscessus_ATCC_199 QLLLDNKAASHGKVVNSAIQYKSTNKVVLLMMVDQSITNTQRPDPRVDKS
MLBr_02597|M.leprae_Br4923 LQVAQAEPATGTVLDAGVERWNDDGSANVLVATEVTSKSPDEKQVLENTN
: : : : . . :*: . .. .
Rv1363c|M.tuberculosis_H37Rv RLKVTVTEEGGQYKMSKVEFVP
Mb1398c|M.bovis_AF2122/97 RLKVTVTEEGGQYKMSKVEFVP
MMAR_3994|M.marinum_M RLRVTVTEEDGQYKMSKVEFVP
MUL_3858|M.ulcerans_Agy99 RLRVTVTEEDGQYKMSKVEFVP
MAV_0938|M.avium_104 RLKVTVTDEGGQYKMSKLEFVP
Mflv_2526|M.gilvum_PYR-GCK RLSVSLVREDGQIKMSKVEFVP
Mvan_4132|M.vanbaalenii_PYR-1 RLSVSLKREDGQIKMAKVEFVP
TH_0392|M.thermoresistible__bu RLFVSVTRDDGQLKMSKVEFVP
MSMEG_4771|M.smegmatis_MC2_155 RLSVTVKQDGDQIKLAKVEFVP
MAB_1004c|M.abscessus_ATCC_199 RMKITMEKIDGRWLASKLEYL-
MLBr_02597|M.leprae_Br4923 RWTATATREGNQWKISNLLQVI
* : ..: ::: :