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MLVVAVPVVVFDPMFAMLLGYQLPDAGWARWVFPVLGTVVYLWGGKPFLVGAVSEIRSRTPGMMLLIGLA ITVAFTASWGASIGVLDHQLSFWWELALLVVIMLAGHWIEMRSLAQTTSALDSLAALLPDTAERVQGQQV VTVPLADLRVGDIVVVRPGGSVPADGRVVEGSASLDESMVTGESAPVRRGVGEQVVAGTVATDSGLRVQV SAVGADTALAGIQRLVADAQASTSRAQRVADTAAGWLFWFALAAAIITAVTWTALGHPDAAVVRAITVLV IACPHALGLAIPLVVSIATERAARGGVLVKDRLALEQMRTVDVVLFDKTGTLTKGTPTLTGIEAAPGHDG DAVLALAAAAETDSEHPLARAIVAAARQRGLDIPAASGFTSEPALGVSAQVAETRVQVGGPALLDARGSR ELAVAAQWRTEGAIILHVLLDGQVAAALRLADDIRPESADTVKALHKLGVRVVMITGDAQAVADTVAGRL GVDRVFAQVRPQDKAAAVAQLQQEGHTVAMVGDGVNDAPALAQADVGIAIGAGTDVAIASAGVILASSDP RSVLSVIELSRASYRKMKQNLWWAAGYNLISVPLAAGVAAPIGFVMPMSAGAVLMSLSTVVVALNSQLLR RLDLRPQTSARNMLNS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0449 | - | - | 100% (646) | copper-transporting ATPase |
| M. abscessus ATCC 19977 | MAB_3984c | - | e-103 | 38.50% (639) | putative metal transporter ATPase |
| M. abscessus ATCC 19977 | MAB_4853c | - | 1e-87 | 38.35% (532) | cation-transporting ATPase G |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0994 | ctpV | 1e-120 | 42.53% (609) | metal cation transporter P-type ATPase CtpV |
| M. gilvum PYR-GCK | Mflv_2852 | - | 0.0 | 76.09% (644) | copper-translocating P-type ATPase |
| M. tuberculosis H37Rv | Rv0969 | ctpV | 1e-120 | 42.69% (609) | metal cation transporter P-type ATPase CtpV |
| M. leprae Br4923 | MLBr_01987 | ctpA | 1e-110 | 39.72% (647) | putative cation-transporting ATPase |
| M. marinum M | MMAR_2536 | - | 1e-124 | 42.34% (633) | metal cation transporter p-type ATPase |
| M. avium 104 | MAV_5246 | - | 1e-105 | 38.34% (652) | copper-translocating P-type ATPase |
| M. smegmatis MC2 155 | MSMEG_5014 | - | 1e-113 | 40.22% (649) | copper-translocating P-type ATPase |
| M. thermoresistible (build 8) | TH_2531 | - | 0.0 | 72.32% (643) | PUTATIVE copper-translocating P-type ATPase |
| M. ulcerans Agy99 | MUL_0423 | ctpV | 1e-123 | 43.44% (610) | metal cation transporter p-type ATPase, CtpV |
| M. vanbaalenii PYR-1 | Mvan_3678 | - | 1e-132 | 43.45% (649) | copper-translocating P-type ATPase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5246|M.avium_104 -----------------MSTPPRHIDEGTFPDHTASTARIELEITGMTCA
MSMEG_5014|M.smegmatis_MC2_155 --------------------------------MTTATGHVELQIGGMTCA
MLBr_01987|M.leprae_Br4923 --------------------------------MRAPNGWNNLP-------
Mb0994|M.bovis_AF2122/97 ---------------MRVCVTGFNVDAVRAVAIEETVSQVTGVHAVHAYP
Rv0969|M.tuberculosis_H37Rv ---------------MRVCVTGFNVDAVRAVAIEETVSQVTGVHAVHAYP
MMAR_2536|M.marinum_M ---------------MRVRISGHHIDAVRAVAIEDVVAEVAGVHAVQAYP
MUL_0423|M.ulcerans_Agy99 ---------------MRVHANGFAIDATRAAAIEESVGRVGGVRAVRAYP
MAB_0449|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2852|M.gilvum_PYR-GCK --------------------------------------------------
TH_2531|M.thermoresistible__bu --------------------------------------------------
Mvan_3678|M.vanbaalenii_PYR-1 MTKSTILDVHGLNWASSTAVVEATLLRRPGVTSVEANAVNQTATVVYDPT
MAV_5246|M.avium_104 SCAARIEKKLNKLDGVTATVNYATEKAAVSAPASYDPQTLITEIENAGYA
MSMEG_5014|M.smegmatis_MC2_155 SCAARIERKLNKLDGVTASVNYATEKASVEVAGEVSPETLIEVVETAGYT
MLBr_01987|M.leprae_Br4923 ----------NKLSDFSTLVNSATRVAAINLSEVTQTAEVCEAVRRAALC
Mb0994|M.bovis_AF2122/97 RTASVVIWYSPELGDTAAVLSAITKAQHVPAELVPARAPHSAGVRGVGVV
Rv0969|M.tuberculosis_H37Rv RTASVVIWYSPELGDTAAVLSAITKAQHVPAELVPARAPHSAGVRGVGVV
MMAR_2536|M.marinum_M RSASVVIWYAPEDCDTAAVLSAISDAQYIPAELVPARAPHSSNPSNTGVV
MUL_0423|M.ulcerans_Agy99 RTASVVIWYSPAHCDTAAIVSAIAEAEHAGDASAPAPAARVAGIADGGVV
MAB_0449|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2852|M.gilvum_PYR-GCK ----------------------MTNHDEHAIAASHTGVHADHDDQGEHAV
TH_2531|M.thermoresistible__bu -----------------------------MVGPAHHGTVAADG-----RA
Mvan_3678|M.vanbaalenii_PYR-1 TTSVADLAGWIRDCGFHCAGRSVPDHVCDPMSEPHHHPSATLDEQPTSAP
MAV_5246|M.avium_104 AAVA--------------------------------TPSPPRD-----DP
MSMEG_5014|M.smegmatis_MC2_155 AHLP--------------------------------APPQPETGGTEQDP
MLBr_01987|M.leprae_Br4923 TDGG--------------------------------EALQRRQ----ADA
Mb0994|M.bovis_AF2122/97 RKITGGIRRMLS----------RPPGVDKPLKASRCGGRPRGPVRGSASW
Rv0969|M.tuberculosis_H37Rv RKITGGIRRMLS----------RPPGVDKPLKASRCGGRPRGPVRGSASW
MMAR_2536|M.marinum_M QKITGGILRLLG----------LSPDTDT--RDTAGEGSCHQPAASCHGA
MUL_0423|M.ulcerans_Agy99 GRVIGGLARALLGMRTDDNDDDPPPEIARLRAALDRIGYSPEQDTATQLS
MAB_0449|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2852|M.gilvum_PYR-GCK QDTN------------------------------VHHDNRGDHGGHAGHG
TH_2531|M.thermoresistible__bu QHLT------------------------------GRDHHRHGHGDHAG--
Mvan_3678|M.vanbaalenii_PYR-1 SPTAGEVHAHEA------------------APARTPQEAMGHGGGHAGMS
MAV_5246|M.avium_104 E---LASLRRRLVTAIALAGP----VIAVAMIPALQFQ-----HWHWAAL
MSMEG_5014|M.smegmatis_MC2_155 EDRATDALRTRLLVSAVLTVP----VIAMAMVPALQFT-----NWQWLSL
MLBr_01987|M.leprae_Br4923 DN--ARYLLIRLAVAAALFVPLAHLSVMFAVLPSTHFP-----GWEWMLT
Mb0994|M.bovis_AF2122/97 PGEQNRRERRTWLPRVWLALPLG-LLALGSSMFFGAYP-----WAGWLAF
Rv0969|M.tuberculosis_H37Rv PGEQNRRERRTWLPRVWLALPLG-LLALGSSMFFGAYP-----WAGWLAF
MMAR_2536|M.marinum_M PAADAKGEQRKWLRRVWLAAPLG-LVSMAAPMLFGAS------WAGWLAF
MUL_0423|M.ulcerans_Agy99 PSEQARSGIRFWSRRAWLAWPLG-LLASGLTMFFGAYP-----WAGWLAF
MAB_0449|M.abscessus_ATCC_1997 --------------MLVVAVPVVVFDPMFAMLLGYQLPDAGWAR--WVFP
Mflv_2852|M.gilvum_PYR-GCK ADHVAVFRK-LFWINLIIAIPVIAFSTMFAMLLGYEVPDVPGGR--WIAP
TH_2531|M.thermoresistible__bu --HVAEFRR-LFWVMLLLAVPTVAFSGMFAMILGYQVPRVPGAQ--WVSP
Mvan_3678|M.vanbaalenii_PYR-1 MDHMVRDMRNRFLVALALSIPIMLWSPMGRDMFGFTVPAPFGLRDDVFTL
: * :
MAV_5246|M.avium_104 ALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLYALVL
MSMEG_5014|M.smegmatis_MC2_155 TLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAFGWSLYALFW
MLBr_01987|M.leprae_Br4923 ALAIPVVTWAAWPFHRVAIHNARYHGASMETLISTGITAATIWSLYTVFG
Mb0994|M.bovis_AF2122/97 AATLPVQFVAGWPILRGAVQQARALTSNMDTLIALGTLTAFVYSTYQLFA
Rv0969|M.tuberculosis_H37Rv AATLPVQFVAGWPILRGAVQQARALTSNMDTLIALGTLTAFVYSTYQLFA
MMAR_2536|M.marinum_M AATVPVQFVAGWPFLKGAVQQARAGSAGMDTLIALGTLTAFAYSTYGLFA
MUL_0423|M.ulcerans_Agy99 AATIPVQFIAGWPFLVGAVQQARARSANMNTLISLGTLTAFIYSTYQLFA
MAB_0449|M.abscessus_ATCC_1997 VLGTVVYLWGGKPFLVGAVSEIRSRTPGMMLLIGLAITVAFTASWGASIG
Mflv_2852|M.gilvum_PYR-GCK LLGTVMYVVGGRPFLTGAVSEIRSRKPGMMLLIGLAITVAFFASWGASLG
TH_2531|M.thermoresistible__bu VLGTVMYVWGGRPFLTGAISEIRSRTPGMMLLIGLALTVAFLSSWGASLG
Mvan_3678|M.vanbaalenii_PYR-1 LLSLPVVFYSAWIFFDGAWRALRARTLDMMVLVAVAVGAGWLYSLGVTL-
: . : * : * *:. . .. * .
MAV_5246|M.avium_104 GAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAGRYFE
MSMEG_5014|M.smegmatis_MC2_155 GTAGVPGMTHPFSLVG------SRTDGAGNIYLEVAAGVTTFILAGRYFE
MLBr_01987|M.leprae_Br4923 HHQSTEHRGVWRALLG-----------SDAIYFEVAAGITVFVLAGKYYT
Mb0994|M.bovis_AF2122/97 GGP---------------------------LFFDTSALIIAFVVLGRHLE
Rv0969|M.tuberculosis_H37Rv GGP---------------------------LFFDTSALIIAFVVLGRHLE
MMAR_2536|M.marinum_M GGP---------------------------LFFDTAALIIAFVVLGRYFE
MUL_0423|M.ulcerans_Agy99 GGP---------------------------LFFDTAALIIAFVVLGRYFE
MAB_0449|M.abscessus_ATCC_1997 VLDHQL------------------------SFWWELALLVVIMLAGHWIE
Mflv_2852|M.gilvum_PYR-GCK VLHHEL------------------------EFWWELALLIVIMLLGHWFE
TH_2531|M.thermoresistible__bu VLDHRL------------------------EFWWELALLIVIMLLGHWIE
Mvan_3678|M.vanbaalenii_PYR-1 -TGGGE------------------------VFYEAASVLTAFVLLGHWFE
: : : ::: *:
MAV_5246|M.avium_104 RRSKRTAGAALRALLALGAKDVAVLR----AGAETRIPIERLAVGDEFVV
MSMEG_5014|M.smegmatis_MC2_155 AKSKRRASAALRALMELGAKDVAILR----NGAEQRIPIDQLGVGDEFVV
MLBr_01987|M.leprae_Br4923 ARAKSHASIALLALAALSAKDAAVLQP---DGSEMVIPANELNEQQRFVV
Mb0994|M.bovis_AF2122/97 ARATGKASEAISKLLELGAKEATLLV----DGQELLVPVDQVQVGDLVRV
Rv0969|M.tuberculosis_H37Rv ARATGKASEAISKLLELGAKEATLLV----DGQELLVPVDQVQVGDLVRV
MMAR_2536|M.marinum_M ARATGKTREAISTLLEMGAKEACLLI----DGQEVLVPVEQVQVGDLLLV
MUL_0423|M.ulcerans_Agy99 ATAHGKTREAISKLLDMGAKETRLIV----DGEEHLVPVDRVQVGDLVRV
MAB_0449|M.abscessus_ATCC_1997 MRSLAQTTSALDSLAALLPDTAERVQ----GQQVVTVPLADLRVGDIVVV
Mflv_2852|M.gilvum_PYR-GCK MRSLAQTTSALDSLAALLPDEAEKVD----GDRIITVSPADLQVGDLVVV
TH_2531|M.thermoresistible__bu LRSLARTTSALDSLAALLPDTAERVEQGPDGETVTVVAPADLRVGDTVIV
Mvan_3678|M.vanbaalenii_PYR-1 MRARGGANDAIRTLLELAPPVAVVLR----DGEPVETPTAEVAVGDLLLI
: : *: * : . . : . : : . :
MAV_5246|M.avium_104 RPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGRL
MSMEG_5014|M.smegmatis_MC2_155 RPGEKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATVNVGGRL
MLBr_01987|M.leprae_Br4923 RPGQTIAADGLVIDGSATVSMSPITGEAKPVRVNPGAQVIGGTVVLNGRL
Mb0994|M.bovis_AF2122/97 RPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAGDRVAGATVNLDGLL
Rv0969|M.tuberculosis_H37Rv RPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAGDRVAGATVNLDGLL
MMAR_2536|M.marinum_M RPGEKIPVDGEITDGRAAVDESMLTGESVPVEKTVGDRVAGATVNTDGLL
MUL_0423|M.ulcerans_Agy99 RPGEKIPVDGEVIDGRAAVDESMLTGESVPVEKGVGDWVAGATVNTDGLL
MAB_0449|M.abscessus_ATCC_1997 RPGGSVPADGRVVEGSASLDESMVTGESAPVRRGVGEQVVAGTVATDSGL
Mflv_2852|M.gilvum_PYR-GCK RPGGSVPADGRIVEGRADMDESMVTGESRPVARGVGDAVTAGTVATDSGL
TH_2531|M.thermoresistible__bu RPGAGIPADGRIIDGVADVDESMVTGESVPVRRGVGDRVVAATVATDSGL
Mvan_3678|M.vanbaalenii_PYR-1 RPGAKIPVDGTVAEGTSDVDESMVTGESLPVSKAPDSKVIGASINTTGTL
*** :..** : * : :. : :***: ** . * ..:: . *
MAV_5246|M.avium_104 VVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLAV
MSMEG_5014|M.smegmatis_MC2_155 VVRANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPIVIALAV
MLBr_01987|M.leprae_Br4923 IVEAAAVGDETQLAGMVRLVEQAQQQNANAQRLADRIASVFVPCVFAVAA
Mb0994|M.bovis_AF2122/97 TVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADRVSAVFVPAVIGVAV
Rv0969|M.tuberculosis_H37Rv TVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADRVSAVFVPAVIGVAV
MMAR_2536|M.marinum_M TVRATAVGADTALAQIVRLVEQAQGGKAPVQRLADRVSAVFVPAVLGVAA
MUL_0423|M.ulcerans_Agy99 TVRATAVGADTALAQIVRLVEEAQGGKAPVQRLADRVSAVFVPVVVRIAA
MAB_0449|M.abscessus_ATCC_1997 RVQVSAVGADTALAGIQRLVADAQASTSRAQRVADTAAGWLFWFALAAAI
Mflv_2852|M.gilvum_PYR-GCK RVEITATGDDTALAGIQRLVTEAQNSSSRAQRLADRAAGWLFWFALGTAA
TH_2531|M.thermoresistible__bu RITVTAVGDDTALAGIRRMVAEAQSSSSRAQRIADTAAGWLFWFALGAAL
Mvan_3678|M.vanbaalenii_PYR-1 RVLATKVGSDTVLAQIVAMVQEAQNSKAPGQRFADRAAFWLVLVALIGGT
: * :* ** : :* ** .: **.** : :. .. .
MAV_5246|M.avium_104 ATLAGWLAAGGTLATALTAAVAVLIIACPCALGLATPTALLVGTGRAAQL
MSMEG_5014|M.smegmatis_MC2_155 ATLGFWLGTGGSVAAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQL
MLBr_01987|M.leprae_Br4923 LTAVGWLIAGSGPDRVFSAAIAVLVIACPCALGLATPTAMMVASGRGAQL
Mb0994|M.bovis_AF2122/97 ATFAGWTLIAANPVAGMTAAVAVLIIACPCALGLATPTAIMVGTGRGAEL
Rv0969|M.tuberculosis_H37Rv ATFAGWTLIAANPVAGMTAAVAVLIIACPCALGLATPTAIMVGTGRGAEL
MMAR_2536|M.marinum_M LTFAGWALIAANPIAGMTAAVSVLIIACPCALGLATPTAIIVGTGRGAEM
MUL_0423|M.ulcerans_Agy99 ATFAGWTLLAANPVAGMTAAVSVLIIACPYALGLATPTAIIVGTGRGADM
MAB_0449|M.abscessus_ATCC_1997 ITAVTWTALGH-PDAAVVRAITVLVIACPHALGLAIPLVVSIATERAARG
Mflv_2852|M.gilvum_PYR-GCK ITAVAWSIVGD-PDASVIRAITVLVIACPHALGLAIPLVVSIATERAARG
TH_2531|M.thermoresistible__bu LTALVWAVLHR-PDFAVVRTITVLVIACPHALGLAIPLVVAIATERAARG
Mvan_3678|M.vanbaalenii_PYR-1 ATFLVWWAVGAGVQTALLFAITVVVITCPDALGLATPTAIMVGTGLGAKR
* * . :::*::*:** ***** * .: :.: .*
MAV_5246|M.avium_104 GVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGTDRATLLR
MSMEG_5014|M.smegmatis_MC2_155 GILIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGEDRDDVLR
MLBr_01987|M.leprae_Br4923 GILLKGHESFEATRAVDTVVFDKTGTLTTGQLKVSAVTAAPGWQANEVLQ
Mb0994|M.bovis_AF2122/97 GILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDVIAGQRRQPNQVLR
Rv0969|M.tuberculosis_H37Rv GILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDVIAGQRRQPDQVLR
MMAR_2536|M.marinum_M GILVKGGEVLEASKKIDTVVFDKTGTLTRGKMQLTDVIPDKRQKSDLVLG
MUL_0423|M.ulcerans_Agy99 GILVKGGEVLEASKKIDTVVFDKTGTLTRAQMELTDVIAGKRRQPDVVLR
MAB_0449|M.abscessus_ATCC_1997 GVLVKDRLALEQMRTVDVVLFDKTGTLTKGTPTLTGIEAAPGHDGDAVLA
Mflv_2852|M.gilvum_PYR-GCK GVLIKDRLALEGMRTVDAVLFDKTGTLTKGEPTVTAIEVRGDLDDDFVLA
TH_2531|M.thermoresistible__bu GVLIKDRIALENMRTVDVVLFDKTGTLTKGQPAVTGITAAGAHSEEDVLR
Mvan_3678|M.vanbaalenii_PYR-1 GVLFKNATALETSARIDTVVMDKTGTLTKGEPEVTDVVVDG-IPEDQVLA
*:*.*. :* :*.:::*****:* . : : :*
MAV_5246|M.avium_104 YAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHGRVDGHA
MSMEG_5014|M.smegmatis_MC2_155 VAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGLGVQGTVEGRA
MLBr_01987|M.leprae_Br4923 MAATVESASEHAVALAIAASTTHR----EPVANFRAVPGHGVSGTVAERA
Mb0994|M.bovis_AF2122/97 LAAAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAVAGHGVRAQVNGGP
Rv0969|M.tuberculosis_H37Rv LAAAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAVAGHGVRAQVNGGP
MMAR_2536|M.marinum_M LAAAVESGSEHPVGAAIVAGARERELEIPAATSFTNLAGHGVRAEVDGQV
MUL_0423|M.ulcerans_Agy99 IAAAVESGSEHPIGAAIVAGARERELEVPPATEFTNLAGHGVRGEVGGKS
MAB_0449|M.abscessus_ATCC_1997 LAAAAETDSEHPLARAIVAAARQRGLDIPAASGFTSEPALGVSAQVAETR
Mflv_2852|M.gilvum_PYR-GCK LAAAAEADSEHPLARAIVKAADERGLTVPRAKGFSSSPAVGVTATVDGHE
TH_2531|M.thermoresistible__bu LAAAAEAPSEHPLARALVAAAQRHGTDLPPATDFASTPGLGVRARVAGRT
Mvan_3678|M.vanbaalenii_PYR-1 MVAAVETESEHPLAGAIVRYAAAHGIASASLTGFRNVPGHGAVATVDGRR
..: * ***.:. *:. : . * . *. . *
MAV_5246|M.avium_104 VAIGRPSWLAERGLRPDAALAAAAARAEHDGKTVVAVGWDGRARGILALA
MSMEG_5014|M.smegmatis_MC2_155 VVVGRPRLFGDPEKSLPRKLADAMEAAQAQGRTAVVVGWDGTARGVLVVA
MLBr_01987|M.leprae_Br4923 VRVGKPSWIASR--CNSTTLVTARRNAELRGETAVFVEIDGEQCGVIAVA
Mb0994|M.bovis_AF2122/97 VVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTAVFVGQDGQVVGVLAVA
Rv0969|M.tuberculosis_H37Rv VVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTAVFVGQDGQVVGVLAVA
MMAR_2536|M.marinum_M VLVGRRKLVDENDLRLSDHLAAVAAELEEQGRTAVFVGRGDRVVGVLAVA
MUL_0423|M.ulcerans_Agy99 VLVGRRKLVDEQHLRLPEQLAAAAADLEERGRTAVYVGQDGQVVGVLAVA
MAB_0449|M.abscessus_ATCC_1997 VQVGGPALLDARGSRE----LAVAAQWRTEGAIILHVLLDGQVAAALRLA
Mflv_2852|M.gilvum_PYR-GCK IRVGGPRLLEEIGAQE----VHAATSWRDEGAIILHVIRDGAVVGGLRLA
TH_2531|M.thermoresistible__bu VRVGGPRLLAETGQTA----PAGSEGWRARGSTVLYVLVDDMIAGAVALA
Mvan_3678|M.vanbaalenii_PYR-1 VAVGNRKLMVEEDVEFGV-LMQRRDELAASGRTAVLVGVDGRGVGVIALA
: :* . * : * .. . : :*
MAV_5246|M.avium_104 DTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIGEVISGALP
MSMEG_5014|M.smegmatis_MC2_155 DAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVGIDDVYAEVLP
MLBr_01987|M.leprae_Br4923 DAVKASAADAVAALHDRGFRTALLTGDNPASAAAVASRIGIDEVIADILP
Mb0994|M.bovis_AF2122/97 DTVKDDAADVVGRLHAMGLQVAMITGDNARTAAAIAKQVGIEKVLAEVLP
Rv0969|M.tuberculosis_H37Rv DTVKDDAADVVGRLHAMGLQVAMITGDNARTAAAIAKQVGIEKVLAEVLP
MMAR_2536|M.marinum_M DTIKDDAVEVVRQLHEMGLQVAMITGDNARTAAAIAGQVGIDRVLAEVLP
MUL_0423|M.ulcerans_Agy99 DTVKDDAADVVSQLHAMGLQVALITGDNARTAAAIAAQVGIDRVLAEVLP
MAB_0449|M.abscessus_ATCC_1997 DDIRPESADTVKALHKLGVRVVMITGDAQAVADTVAGRLGVDRVFAQVRP
Mflv_2852|M.gilvum_PYR-GCK DEIRPESRDAVDALHKLGVEVVMITGDAEAVAQAVGHELGIDRVFAGVRP
TH_2531|M.thermoresistible__bu DEIRPESRPTVDALHRQGIDVALITGDARSVAESVAAELGIDRVLADVPP
Mvan_3678|M.vanbaalenii_PYR-1 DAVRETSAEAVSALHDLGVEVVMLSGDNQATADRIAAQLGIDTVIAEVLP
* :: : .: : *. :::** * . .:*: * : *
MAV_5246|M.avium_104 ADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGTGTDVAIEAA
MSMEG_5014|M.smegmatis_MC2_155 QDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGTGTDVAIEAG
MLBr_01987|M.leprae_Br4923 EDKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVAIGAA
Mb0994|M.bovis_AF2122/97 QDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEAS
Rv0969|M.tuberculosis_H37Rv QDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEAS
MMAR_2536|M.marinum_M EDKVNEVRRLQDEGRLVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEAS
MUL_0423|M.ulcerans_Agy99 ADKVNEVRRLQDEGRIVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEAS
MAB_0449|M.abscessus_ATCC_1997 QDKAAAVAQLQQEGHTVAMVGDGVNDAPALAQADVGIAIGAGTDVAIASA
Mflv_2852|M.gilvum_PYR-GCK EDKASKVAALQQEGKKVAMVGDGVNDAPALAQADVGIAIGAGTDVAIASA
TH_2531|M.thermoresistible__bu EHKAAKVVELQREGRRVAMVGDGVNDAPALARADVGIAIGAGTDVAIASA
Mvan_3678|M.vanbaalenii_PYR-1 GDKAAKIAELQRQGKKVAMVGDGVNDAPALAQADLGVAIGAGTDVAIETA
.*. : *: *: *******:**..**. **:*:::* ****** :.
MAV_5246|M.avium_104 DVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAIPLAALGMLN
MSMEG_5014|M.smegmatis_MC2_155 DLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNVAALPLAAAGLLN
MLBr_01987|M.leprae_Br4923 DIILVRDNLDVVPITLDLAAATMRTIKFNMVWAFGYNIAAIPIAAAGLLN
Mb0994|M.bovis_AF2122/97 DITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAFGYNTAAIPLAALGALN
Rv0969|M.tuberculosis_H37Rv DITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAFGYNTAAIPLAALGALN
MMAR_2536|M.marinum_M DITLMSGRLDGVVRSLQLSRQTLRTIHQNLGWAFGYNTAAIPLAAFGLLN
MUL_0423|M.ulcerans_Agy99 DITLMSGRLDGVVSAIELSRRTLRTIYQNLGWAFGYNTAAIPLAALGVLN
MAB_0449|M.abscessus_ATCC_1997 GVILASSDPRSVLSVIELSRASYRKMKQNLWWAAGYNLISVPLAAGVAAP
Mflv_2852|M.gilvum_PYR-GCK GVILASSDPRSVLSVIELSRASYRKMKQNLWWGAGYNLIAVPLAAGVLAP
TH_2531|M.thermoresistible__bu GVVLAGSDPRSVLSVLQLSRAAYRKMKQNLWWAAGYNLIAVPLAAGVLAP
Mvan_3678|M.vanbaalenii_PYR-1 DLVLMRSDPLDVAIALQIGRGTLRKMRQNLGWAVGYNVIALPIAAGVFVP
.: : . . : :. : .: *: *. .** ::*:**
MAV_5246|M.avium_104 -------PMLAGAAMALSSVLVVGNSLRLRSFASIIPGA-----------
MSMEG_5014|M.smegmatis_MC2_155 -------PMLAGAAMAFSSVFVVSNSLRLKRFR-----------------
MLBr_01987|M.leprae_Br4923 -------PLVAGAAMAFSSFFVVSNSLRLRNFGAILSCGTSRHRTVKRWR
Mb0994|M.bovis_AF2122/97 -------PVVAGAAMGFSSVSVVTNSLRLRRFGRDGRTA-----------
Rv0969|M.tuberculosis_H37Rv -------PVVAGAAMGFSSVSVVTNSLRLRRFGRDGRTA-----------
MMAR_2536|M.marinum_M -------PVVAGAAMGLSSVSVVTNSLRLRRFGRDT--------------
MUL_0423|M.ulcerans_Agy99 -------PVVAGAAMGLSSVSVVTNSLRLRRFGRDV--------------
MAB_0449|M.abscessus_ATCC_1997 -IGFVMPMSAGAVLMSLSTVVVALNSQLLRRLDLRPQTSARNMLNS----
Mflv_2852|M.gilvum_PYR-GCK -IGFVLPMSVGAILMSLSTIVVALNAQLLRRLDLSPEASTRAVLNR----
TH_2531|M.thermoresistible__bu -AGFVMPMSVGAILMSLSTVVVALNAQLLRRLDLRPEQSLAAARR-----
Mvan_3678|M.vanbaalenii_PYR-1 SLGLVLRPEIAALSMSGSSFIVAVNALMLKRLKLPVPASAEAGAKS----
.. *. *:. *. *: *: :
MAV_5246|M.avium_104 -----------------------------------
MSMEG_5014|M.smegmatis_MC2_155 -----------------------------------
MLBr_01987|M.leprae_Br4923 CPPPTRLRSTACSPVDASPLRPVAHRTGVKPPTHR
Mb0994|M.bovis_AF2122/97 -----------------------------------
Rv0969|M.tuberculosis_H37Rv -----------------------------------
MMAR_2536|M.marinum_M -----------------------------------
MUL_0423|M.ulcerans_Agy99 -----------------------------------
MAB_0449|M.abscessus_ATCC_1997 -----------------------------------
Mflv_2852|M.gilvum_PYR-GCK -----------------------------------
TH_2531|M.thermoresistible__bu -----------------------------------
Mvan_3678|M.vanbaalenii_PYR-1 -----------------------------------