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M. marinum M MMAR_1448 (-)

annotation: zinc cation transport ATPase
coordinates: 1756710 - 1759259
length: 849

SSVDVIVPVGAALVIAGLAWYFFAPRRAHAASLSEGVQRILVTIRGGYSPNVVQVRQGAPVEIEFDRQES
GDCSSRVVFPDLHLSAALPAHQRTTVRFTPQQAGSFGFFCSMNMINGTLVVTPDGQAAGSAEPEQPNASI
GYAATNSGDEPAAAEIEAAQAQERRAEITDLSRRVAFGAVLSAPVLYAVMAQPLGAGWVPAVLLHHWLQL
ALITPVMFYVGWPIHRTGWLALAHRSADMNSLITLGTFAAYGYSLLVTAASTALPAELQDVYYEAVGVIL
TLIMLGRLLEARAKAGTGEAIRALLGLQARTARVIRNGTQAEIPVDEVVVGDDILVRPGEKIAVDATVVS
GQSTVDESMVTGESMPVTKHTGDTVIGATVNTTGSLRIRAAKVGADTMLAQIIGMVQQAQASRAPIQRLA
DAISAYFVPVVIAIAIATFAVWFVAGPTPELTQALVSAVAVLIIACPCALGLATPLSIMVGTGKGARAGI
LIRSAEALETAHKLDTIVLDKTGTVTAGRPALTDVEVTGTLQQNELLALVAAAEANSEHPVATAVLAGSR
DRGIDHSAADDFASITGKGVRATVAGRTVLVGTATLLAENNVTTSELERIGADLAAKGKTPILAAVDGRP
AGVLAVADTVKDDSMAAIAALGKLGLQVVMITGDNARTAKAIARQVGVSRVLAEVLPEHKAGEIRRLQAE
GRTVGMVGDGINDAPALAQADVGLAIGTGTDVAIEAADITLISGSLAGVVTAIQLSRATMRNIRENLFFA
LIYNAIGIPLAAGVLYPTLGLRLSPMIAAAAMALSSLSVVGNANRLRRYRVEPLPPAEAPTTEPRVETVT
AQSESGDR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1448--100% (849)zinc cation transport ATPase
M. marinum MMMAR_2536-e-17150.15% (680) metal cation transporter p-type ATPase
M. marinum MMMAR_4876ctpVe-16852.93% (614) metal cation transporter p-type ATPase, CtpV

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0994ctpV1e-16652.12% (614) metal cation transporter P-type ATPase CtpV
M. gilvum PYR-GCKMflv_2849-1e-16546.43% (715) heavy metal translocating P-type ATPase
M. tuberculosis H37RvRv0969ctpV1e-16551.95% (614) metal cation transporter P-type ATPase CtpV
M. leprae Br4923MLBr_02000ctpB1e-13339.28% (751) cation-transporting ATPase
M. abscessus ATCC 19977MAB_3984c-1e-14144.21% (656) putative metal transporter ATPase
M. avium 104MAV_5246-1e-14640.67% (772) copper-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_5014-1e-16246.37% (716) copper-translocating P-type ATPase
M. thermoresistible (build 8)TH_4361-1e-16146.92% (697) PUTATIVE heavy metal translocating P-type ATPase
M. ulcerans Agy99MUL_0423ctpV1e-16652.44% (614) metal cation transporter p-type ATPase, CtpV
M. vanbaalenii PYR-1Mvan_4449-1e-16146.61% (693) heavy metal translocating P-type ATPase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_5014|M.smegmatis_MC2_155      ---------------------------------MTTATGHVELQIGG---
Mvan_4449|M.vanbaalenii_PYR-1       -------------------------------------MNTIELSIGG---
Mflv_2849|M.gilvum_PYR-GCK          -----------------------------MTTSIPVSGPSIELRIGG---
MAV_5246|M.avium_104                ------------------MSTPPRHIDEGTFPDHTASTARIELEITG---
TH_4361|M.thermoresistible__bu      --------------------------------MNTGGMNTVTLTVGG---
MAB_3984c|M.abscessus_ATCC_199      ------------------------------METTNTGMETTDLRLHG---
MLBr_02000|M.leprae_Br4923          ----------------------MTASLVEDTNNNHESVRRIQLDVAG---
Mb0994|M.bovis_AF2122/97            --------------------MRVCVTGFNVDAVRAVAIEETVSQVTG---
Rv0969|M.tuberculosis_H37Rv         --------------------MRVCVTGFNVDAVRAVAIEETVSQVTG---
MUL_0423|M.ulcerans_Agy99           --------------------MRVHANGFAIDATRAAAIEESVGRVGG---
MMAR_1448|M.marinum_M               MSSVDVIVPVGAALVIAGLAWYFFAPRRAHAASLSEGVQRILVTIRGGYS
                                                                                : *   

MSMEG_5014|M.smegmatis_MC2_155      --MTCASCAARIERKLNKLD----GVTASVNYATEKASVEVAGEVSPETL
Mvan_4449|M.vanbaalenii_PYR-1       --MTCASCAARVEKKLNKLD----GVTATVNFATEKARVAFGDEVSPGQL
Mflv_2849|M.gilvum_PYR-GCK          --MTCASCANRIERKLNKID----GVAATVNYATEKATVTVPDGYDPALL
MAV_5246|M.avium_104                --MTCASCAARIEKKLNKLD----GVTATVNYATEKAAVSAPASYDPQTL
TH_4361|M.thermoresistible__bu      --MTCASCAARVEKRLNRID----GVVATVNFATEQATVRYPDHVDPADL
MAB_3984c|M.abscessus_ATCC_199      --MTCASCASRVEKGLNKIT----GVNARVNLALESARVEHDGSVTGEDL
MLBr_02000|M.leprae_Br4923          --MLCAACASRVETKLNKIP----GVRASVNFATRVATIDAVD-VAVDEL
Mb0994|M.bovis_AF2122/97            --VHAVHAYPRTASVVIWYSPELGDTAAVLSAITKAQHVPAELVPARAPH
Rv0969|M.tuberculosis_H37Rv         --VHAVHAYPRTASVVIWYSPELGDTAAVLSAITKAQHVPAELVPARAPH
MUL_0423|M.ulcerans_Agy99           --VRAVRAYPRTASVVIWYSPAHCDTAAIVSAIAEAEHAGDASAPAPAAR
MMAR_1448|M.marinum_M               PNVVQVRQGAPVEIEFDRQESGDCSSRVVFPDLHLSAALPAHQRTTVRFT
                                      :  .         .        .  . .                    

MSMEG_5014|M.smegmatis_MC2_155      IEVVETAGYTAHLPA-PPQPE-----------------------------
Mvan_4449|M.vanbaalenii_PYR-1       VSAVESAGYQAELPE-RPD-------------------------------
Mflv_2849|M.gilvum_PYR-GCK          IAEVQNAGYSAALPT-PEKPA-----------------------------
MAV_5246|M.avium_104                ITEIENAGYAAAVAT-PSPP------------------------------
TH_4361|M.thermoresistible__bu      IAAIEATGYTASLPA-PQRDTG----------------------------
MAB_3984c|M.abscessus_ATCC_199      VKAVESVGYTAQVVGGSHQDAH----------------------------
MLBr_02000|M.leprae_Br4923          RQVIEQAGYRATAHAESAVEE-----------------------------
Mb0994|M.bovis_AF2122/97            SAGVRGVGVVRKITGGIRRMLS--------------RPPGVDKPLKASRC
Rv0969|M.tuberculosis_H37Rv         SAGVRGVGVVRKITGGIRRMLS--------------RPPGVDKPLKASRC
MUL_0423|M.ulcerans_Agy99           VAGIADGGVVGRVIGGLARALLGMRTDDN----DDDPPPEIARLRAALDR
MMAR_1448|M.marinum_M               PQQAGSFGFFCSMNMINGTLVVTPDGQAAGSAEPEQPNASIGYAATNSGD
                                           *                                          

MSMEG_5014|M.smegmatis_MC2_155      ------TGGTEQDPEDRATDALRTRLLVSAVLTVPVI--AMA----MVPA
Mvan_4449|M.vanbaalenii_PYR-1       ---------EPAEPTDDPTAALKRRLLICVALSVPVI--AMA----MVPV
Mflv_2849|M.gilvum_PYR-GCK          ------LTGETGETEDPDLVSLRHRLTGSVLLSVPVI--AMA----MIPV
MAV_5246|M.avium_104                -------------RDDPELASLRRRLVTAIALAGPVI--AVA----MIPA
TH_4361|M.thermoresistible__bu      GAPAGAATGAAGDDHDAEAERWRRRLTISAALSIPVV--VLS----MIPA
MAB_3984c|M.abscessus_ATCC_199      AGDHDGHDPHDHMNHDVPDDQLKSRLIGSLILAIPVV--VIS----MAMP
MLBr_02000|M.leprae_Br4923          -----------IDPDADYARNLLRRLIVAALLFVPLA--DLSTMFAIVPT
Mb0994|M.bovis_AF2122/97            GGRPRGPVRGSASWPGEQNRRERRTWLPRVWLALPLG--LLALG-SSMFF
Rv0969|M.tuberculosis_H37Rv         GGRPRGPVRGSASWPGEQNRRERRTWLPRVWLALPLG--LLALG-SSMFF
MUL_0423|M.ulcerans_Agy99           IGYSPEQDTATQLSPSEQARSGIRFWSRRAWLAWPLG--LLASG-LTMFF
MMAR_1448|M.marinum_M               EPAAAEIEAAQAQERRAEITDLSRRVAFGAVLSAPVLYAVMAQPLGAGWV
                                                                   *  *:    ::        

MSMEG_5014|M.smegmatis_MC2_155      LQFTNWQWLSLTLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLA
Mvan_4449|M.vanbaalenii_PYR-1       LQFTYWQWLSLTLAAPVVVWGAWPFHQAAWTNLRHGTATMDTLISIGTLA
Mflv_2849|M.gilvum_PYR-GCK          LQFTYWQWASLVLAAPVIVWAAWPFHRAAWANLRHATATMDTLISLGTLS
MAV_5246|M.avium_104                LQFQHWHWAALALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLA
TH_4361|M.thermoresistible__bu      LQFTHWQWLALTLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTA
MAB_3984c|M.abscessus_ATCC_199      LHFSGWEILVAALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIA
MLBr_02000|M.leprae_Br4923          NRFPGWGYLLTALAAPIVTWAAWPFHRVALRNARYRAASMETLISAGILA
Mb0994|M.bovis_AF2122/97            GAYPWAGWLAFAATLPVQFVAGWPILRGAVQQARALTSNMDTLIALGTLT
Rv0969|M.tuberculosis_H37Rv         GAYPWAGWLAFAATLPVQFVAGWPILRGAVQQARALTSNMDTLIALGTLT
MUL_0423|M.ulcerans_Agy99           GAYPWAGWLAFAATIPVQFIAGWPFLVGAVQQARARSANMNTLISLGTLT
MMAR_1448|M.marinum_M               PAVLLHHWLQLALITPVMFYVGWPIHRTGWLALAHRSADMNSLITLGTFA
                                               .   *:    . *:   .        : *::*:: *  :

MSMEG_5014|M.smegmatis_MC2_155      AFGWSLYALFWGTAGVPGMTHPFSLVGSR------TDGAGNIYLEVAAGV
Mvan_4449|M.vanbaalenii_PYR-1       ALGWSIYALFWGTAGIPGMTHPFELTIAR------TDGTSNIYLEAAAGV
Mflv_2849|M.gilvum_PYR-GCK          AFLWSLYALFFGTAGTPGMKHPFELTLAP------SHGAANIYLEVAAGV
MAV_5246|M.avium_104                AFLWSLYALVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGV
TH_4361|M.thermoresistible__bu      AYLWSLWALFFTAAGMPGMTMTFTLLPAD-------TGEPHIYLEVAAAV
MAB_3984c|M.abscessus_ATCC_199      AYLWSLWVLFANAGHT--------------------HGDVHVYFEVVAAV
MLBr_02000|M.leprae_Br4923          ATGWSLSTIFVDKEPRQTHGIWQAILHSD-----------SIYFEVAAGV
Mb0994|M.bovis_AF2122/97            AFVYSTYQLFAG---------------------------GPLFFDTSALI
Rv0969|M.tuberculosis_H37Rv         AFVYSTYQLFAG---------------------------GPLFFDTSALI
MUL_0423|M.ulcerans_Agy99           AFIYSTYQLFAG---------------------------GPLFFDTAALI
MMAR_1448|M.marinum_M               AYGYSLLVTAASTALP--------------------AELQDVYYEAVGVI
                                    *  :*                                    :: :. . :

MSMEG_5014|M.smegmatis_MC2_155      TTFILAGRYFEAKSKRRASAALRALMELGAKDVAILR-NGAEQRIPIDQL
Mvan_4449|M.vanbaalenii_PYR-1       TTFILAGRYFEARAKRRAGAALRALLELGAREVTVRR-GGAEQRIPIEQL
Mflv_2849|M.gilvum_PYR-GCK          TTFILAGRYFEKRSKRQAGAALRALLEMGAKEVSVLR-DGVESKIAVEDL
MAV_5246|M.avium_104                TLFVLAGRYFERRSKRTAGAALRALLALGAKDVAVLR-AGAETRIPIERL
TH_4361|M.thermoresistible__bu      TTFIIAGRYFEARAKRQSGAALRALLDMGANDVAVLR-DGAEKRVPIGEL
MAB_3984c|M.abscessus_ATCC_199      TVFLLAGRFAESRAKRSAGSALRALLSLGAKDVAVLR-GGHETRIPVDQL
MLBr_02000|M.leprae_Br4923          TVFVLAGRFFEARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPAGEL
Mb0994|M.bovis_AF2122/97            IAFVVLGRHLEARATGKASEAISKLLELGAKEATLLV-DGQELLVPVDQV
Rv0969|M.tuberculosis_H37Rv         IAFVVLGRHLEARATGKASEAISKLLELGAKEATLLV-DGQELLVPVDQV
MUL_0423|M.ulcerans_Agy99           IAFVVLGRYFEATAHGKTREAISKLLDMGAKETRLIV-DGEEHLVPVDRV
MMAR_1448|M.marinum_M               LTLIMLGRLLEARAKAGTGEAIRALLGLQARTARVIR-NGTQAEIPVDEV
                                      ::: **  *  :   :  *:  *    *. . :    * :  :.   :

MSMEG_5014|M.smegmatis_MC2_155      GVGDEFVVRPGEKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGA
Mvan_4449|M.vanbaalenii_PYR-1       VIGDEFVVRPGEKIAADGTVVEGASAVDASMLTGESVPEEVQPGDQVVGA
Mflv_2849|M.gilvum_PYR-GCK          VVGDEFVVRPGEKIATDGVVASGTSAVDASMLTGESVPVEVGPGDTVVGA
MAV_5246|M.avium_104                AVGDEFVVRPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGG
TH_4361|M.thermoresistible__bu      HVGDVFVVRPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGA
MAB_3984c|M.abscessus_ATCC_199      AVGDEFVVRPGERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGG
MLBr_02000|M.leprae_Br4923          KKQQHFLVRPGETITADGVVIDGTATIDMSAITGEARPVHASPASTVVGG
Mb0994|M.bovis_AF2122/97            QVGDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAGDRVAGA
Rv0969|M.tuberculosis_H37Rv         QVGDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAGDRVAGA
MUL_0423|M.ulcerans_Agy99           QVGDLVRVRPGEKIPVDGEVIDGRAAVDESMLTGESVPVEKGVGDWVAGA
MMAR_1448|M.marinum_M               VVGDDILVRPGEKIAVDATVVSGQSTVDESMVTGESMPVTKHTGDTVIGA
                                       : . ***** :..*. *  * :::* : :***: *     .. * *.

MSMEG_5014|M.smegmatis_MC2_155      TVNVGGRLVVRANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFV
Mvan_4449|M.vanbaalenii_PYR-1       TVNVDGRLVVRADRVGSDTQLAQMARMVEDAQNGKAQAQRLADRISGVFV
Mflv_2849|M.gilvum_PYR-GCK          TVNAGGRLVVRAARVGSDTQLAQMAQLVENAQTGKAQVQRLADRISGVFV
MAV_5246|M.avium_104                TVNAGGRLVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFV
TH_4361|M.thermoresistible__bu      TVNVGGHLQVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFV
MAB_3984c|M.abscessus_ATCC_199      YVNTHGRIVVRANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFV
MLBr_02000|M.leprae_Br4923          TTVLDGRLVIEATAVGGDTQFAAMVRLVEDAQVQKARVQHLADRIAAVFV
Mb0994|M.bovis_AF2122/97            TVNLDGLLTVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADRVSAVFV
Rv0969|M.tuberculosis_H37Rv         TVNLDGLLTVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADRVSAVFV
MUL_0423|M.ulcerans_Agy99           TVNTDGLLTVRATAVGADTALAQIVRLVEEAQGGKAPVQRLADRVSAVFV
MMAR_1448|M.marinum_M               TVNTTGSLRIRAAKVGADTMLAQIIGMVQQAQASRAPIQRLADAISAYFV
                                     .   * : :.*  :* ** :* :  :*  **  :*  *:*** ::. **

MSMEG_5014|M.smegmatis_MC2_155      PIVIALAVATLGFWLG--TGGSVAAAFTAAVAVLIIACPCALGLATPTAL
Mvan_4449|M.vanbaalenii_PYR-1       PIVIALSVATLGFWIG--SGFPVAAAFTAAVAVLIIACPCALGLATPTAL
Mflv_2849|M.gilvum_PYR-GCK          PIVLAIAVITLGAWLG--AGFPVAAAFTAAVAVLVIACPCALGLATPTAL
MAV_5246|M.avium_104                PVVLLLAVATLAGWLA--AGGTLATALTAAVAVLIIACPCALGLATPTAL
TH_4361|M.thermoresistible__bu      PIVIALSALTLAGWLLL-TDAPVSAAFTAAVAVLIIACPCALGLATPTAL
MAB_3984c|M.abscessus_ATCC_199      PVVLAISALTFVAWAA--LGNSLASAFTAAVAVLIIACPCALGLATPTAI
MLBr_02000|M.leprae_Br4923          PMVFVIAGLAGASWLL--AGASPDRAFSVVLGVLVIACPCTLGLATPTAM
Mb0994|M.bovis_AF2122/97            PAVIGVAVATFAGWTLI-AANPVAG-MTAAVAVLIIACPCALGLATPTAI
Rv0969|M.tuberculosis_H37Rv         PAVIGVAVATFAGWTLI-AANPVAG-MTAAVAVLIIACPCALGLATPTAI
MUL_0423|M.ulcerans_Agy99           PVVVRIAAATFAGWTLL-AANPVAG-MTAAVSVLIIACPYALGLATPTAI
MMAR_1448|M.marinum_M               PVVIAIAIATFAVWFVAGPTPELTQALVSAVAVLIIACPCALGLATPLSI
                                    * *. ::  :   *            :  .:.**:**** :****** ::

MSMEG_5014|M.smegmatis_MC2_155      LVGTGRGAQLGILIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVA
Mvan_4449|M.vanbaalenii_PYR-1       MVGTGRGAQLGILIKGPEVLEDTRRVDTVILDKTGTVTTGSMTLVDVFAA
Mflv_2849|M.gilvum_PYR-GCK          LVGTGRGAQMGVLIKGPEVLESTRKVDTVVLDKTGTVTTGKMTLVDVVTA
MAV_5246|M.avium_104                LVGTGRAAQLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAA
TH_4361|M.thermoresistible__bu      LVGTGRGAQLGILIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVA
MAB_3984c|M.abscessus_ATCC_199      LVGTGRGAQLGVLIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRS
MLBr_02000|M.leprae_Br4923          MVASGRGAQLGIFIKGYRALETINAIDTVVFDKTGTLTLGQLSVSTVTST
Mb0994|M.bovis_AF2122/97            MVGTGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDVIAG
Rv0969|M.tuberculosis_H37Rv         MVGTGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDVIAG
MUL_0423|M.ulcerans_Agy99           IVGTGRGADMGILVKGGEVLEASKKIDTVVFDKTGTLTRAQMELTDVIAG
MMAR_1448|M.marinum_M               MVGTGKGARAGILIRSAEALETAHKLDTIVLDKTGTVTAGRPALTDVEVT
                                    :*.:*:.*  *::::. ..**  . :**:::*****:* .   :  *   

MSMEG_5014|M.smegmatis_MC2_155      DGE---DRDDVLRVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANI
Mvan_4449|M.vanbaalenii_PYR-1       EGE---QPDEVLRVAGAVESSSEHPIARAIAAGAQEKFGELPAVTAFTNL
Mflv_2849|M.gilvum_PYR-GCK          PGT---DRGNLLRLAGALENASEHPIAQAVATAATEELGTLPTPEDFANV
MAV_5246|M.avium_104                DGT---DRATLLRYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAV
TH_4361|M.thermoresistible__bu      DGL---SETELLRLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENH
MAB_3984c|M.abscessus_ATCC_199      IGSGVADADEILRIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNE
MLBr_02000|M.leprae_Br4923          GGW---CSGEVLALASAVEAASEHSVATAIVAAYADPR----PVADFVAF
Mb0994|M.bovis_AF2122/97            QRR---QPNQVLRLAAAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAV
Rv0969|M.tuberculosis_H37Rv         QRR---QPDQVLRLAAAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAV
MUL_0423|M.ulcerans_Agy99           KRR---QPDVVLRIAAAVESGSEHPIGAAIVAGARERELEVPPATEFTNL
MMAR_1448|M.marinum_M               GTL---QQNELLALVAAAEANSEHPVATAVLAGSRDRGIDHSAADDFASI
                                              :*  ..: *  ***.:. *:                *   

MSMEG_5014|M.smegmatis_MC2_155      EGLGVQGTVEGRAVVVGRPRLFGDPEKSLPRKLADAMEAAQAQGRTAVVV
Mvan_4449|M.vanbaalenii_PYR-1       RGLGVSGQVDGRAVLLGRLRLLADRSHEIPSELEVAVARAESDGRTAVVV
Mflv_2849|M.gilvum_PYR-GCK          EGKGVQGIVDGHAVVVGRESLLADWSQHLSPELARAKASAEAQGKTAVAV
MAV_5246|M.avium_104                GGGGVHGRVDGHAVAIGRPSWLAERGLRPDAALAAAAARAEHDGKTVVAV
TH_4361|M.thermoresistible__bu      GGNGVSGRVDGHDVRVGRLAWLG---LSAGDRLRNAAAQAEAAGHTPVWV
MAB_3984c|M.abscessus_ATCC_199      PGVGVSGVVDGQEVSI----------------------EAIEGQNTTAAV
MLBr_02000|M.leprae_Br4923          AGCGVSGVVAEHHVKIGKPSWVTRN-APCDVVLESARREGESRGETVVFV
Mb0994|M.bovis_AF2122/97            AGHGVRAQVNGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTAVFV
Rv0969|M.tuberculosis_H37Rv         AGHGVRAQVNGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTAVFV
MUL_0423|M.ulcerans_Agy99           AGHGVRGEVGGKSVLVGRRKLVDEQHLRLPEQLAAAAADLEERGRTAVYV
MMAR_1448|M.marinum_M               TGKGVRATVAGRTVLVGTATLLAEN-NVTTSELERIGADLAAKGKTPILA
                                     * ** . *    * :                            .*   .

MSMEG_5014|M.smegmatis_MC2_155      GWDGTARGVLVVADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIAD
Mvan_4449|M.vanbaalenii_PYR-1       GWDGQARGVLMVADAVKPTSAEAISLLKRLGLTPIMVTGDNEAVARAVAA
Mflv_2849|M.gilvum_PYR-GCK          GWDGEARGVLVVADTVKPTSAQAISQMREIGLTPVLLTGDNEAVARQIAA
MAV_5246|M.avium_104                GWDGRARGILALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAG
TH_4361|M.thermoresistible__bu      AVDGRIAGVIVVSDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAA
MAB_3984c|M.abscessus_ATCC_199      SWGGLRRGEIEVADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVAS
MLBr_02000|M.leprae_Br4923          SVDGVACGAVAIADTVKDSAADAISALCSRGLHTILLTGDNQAAARAVAA
Mb0994|M.bovis_AF2122/97            GQDGQVVGVLAVADTVKDDAADVVGRLHAMGLQVAMITGDNARTAAAIAK
Rv0969|M.tuberculosis_H37Rv         GQDGQVVGVLAVADTVKDDAADVVGRLHAMGLQVAMITGDNARTAAAIAK
MUL_0423|M.ulcerans_Agy99           GQDGQVVGVLAVADTVKDDAADVVSQLHAMGLQVALITGDNARTAAAIAA
MMAR_1448|M.marinum_M               AVDGRPAGVLAVADTVKDDSMAAIAALGKLGLQVVMITGDNARTAKAIAR
                                    . .*   * : ::*:**  :  .:  :   *    ::****  .*   * 

MSMEG_5014|M.smegmatis_MC2_155      QVGID--DVYAEVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADL
Mvan_4449|M.vanbaalenii_PYR-1       EVGID--EVIAGVLPQDKVDTVKRLQRDGKVVAMVGDGVNDAAALAQADL
Mflv_2849|M.gilvum_PYR-GCK          EVGID--TVIAEVMPKDKVDVIVRLQAEGKTVAMVGDGVNDAPALAQADL
MAV_5246|M.avium_104                ELGIG--EVISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADL
TH_4361|M.thermoresistible__bu      QVGID--DVIAGVLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADL
MAB_3984c|M.abscessus_ATCC_199      EVGIAAGDVIAGVKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADI
MLBr_02000|M.leprae_Br4923          QVGID--TVIADMLPEAKVDVIQRLRDQGHTVAMVGDGINDGPALACADL
Mb0994|M.bovis_AF2122/97            QVGIE--KVLAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQADL
Rv0969|M.tuberculosis_H37Rv         QVGIE--KVLAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQADL
MUL_0423|M.ulcerans_Agy99           QVGID--RVLAEVLPADKVNEVRRLQDEGRIVAMVGDGVNDAPALVQADL
MMAR_1448|M.marinum_M               QVGVS--RVLAEVLPEHKAGEIRRLQAEGRTVGMVGDGINDAPALAQADV
                                    ::*:    * :   *  *.  : :*:  *: *.*:***:**..**. **:

MSMEG_5014|M.smegmatis_MC2_155      GLSMGTGTDVAIEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFA
Mvan_4449|M.vanbaalenii_PYR-1       GLAMGSGTDVAIEASDLTLVSNDLRAVPDAIRLSRKTLSTIKGNLFWAFA
Mflv_2849|M.gilvum_PYR-GCK          GLAMGTGTDVAIEASDITLVRGDLRSAVDAIRLSRRTLSTIKTNLFWAFV
MAV_5246|M.avium_104                GLAMGTGTDVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFG
TH_4361|M.thermoresistible__bu      GLAIGTGTDVAIEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFA
MAB_3984c|M.abscessus_ATCC_199      GMAMGTGTDAAIEASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFA
MLBr_02000|M.leprae_Br4923          GLAMGRGTDVAIGAADLILVRDSLGVVPVALDLARATMRTIRINMIWAFG
Mb0994|M.bovis_AF2122/97            GIAIGTGTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAFG
Rv0969|M.tuberculosis_H37Rv         GIAIGTGTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAFG
MUL_0423|M.ulcerans_Agy99           GIAIGTGTDVAIEASDITLMSGRLDGVVSAIELSRRTLRTIYQNLGWAFG
MMAR_1448|M.marinum_M               GLAIGTGTDVAIEAADITLISGSLAGVVTAIQLSRATMRNIRENLFFALI
                                    *:::* ***.** *.*: :: . *  .  *: *.* *: .*  *: :*: 

MSMEG_5014|M.smegmatis_MC2_155      YNVAALPLAA------AGL-LNPMLAGAAMAFSSVFVVSNSLRLKRFR--
Mvan_4449|M.vanbaalenii_PYR-1       YNVAALPLAA------AGL-LNPMIAGAAMAFSSVFVVSNSLRLRAFTPS
Mflv_2849|M.gilvum_PYR-GCK          YNVAAIPVAA------LGM-LNPMLAGAAMAFSSVFVVGNSLRLRGFTST
MAV_5246|M.avium_104                YNLAAIPLAA------LGM-LNPMLAGAAMALSSVLVVGNSLRLRSFASI
TH_4361|M.thermoresistible__bu      YNVAALPLAA------AGL-LNPLIAGAAMAFSSVFVVSNSLRLRRFTPS
MAB_3984c|M.abscessus_ATCC_199      YNTAAIPLAA------LGL-LNPMIAGAAMAMSSVFVVLNSLRLRTFR--
MLBr_02000|M.leprae_Br4923          YNVAAIPIAS------SGL-LNPLIAGAAMAFSSFFVVSNSLRLSNFGLS
Mb0994|M.bovis_AF2122/97            YNTAAIPLAA------LGA-LNPVVAGAAMGFSSVSVVTNSLRLRRFGRD
Rv0969|M.tuberculosis_H37Rv         YNTAAIPLAA------LGA-LNPVVAGAAMGFSSVSVVTNSLRLRRFGRD
MUL_0423|M.ulcerans_Agy99           YNTAAIPLAA------LGV-LNPVVAGAAMGLSSVSVVTNSLRLRRFGRD
MMAR_1448|M.marinum_M               YNAIGIPLAAGVLYPTLGLRLSPMIAAAAMALSSLSVVGNANRLRRYRVE
                                    **  .:*:*:       *  *.*::*.***.:**. ** *: **  :   

MSMEG_5014|M.smegmatis_MC2_155      --------------------------
Mvan_4449|M.vanbaalenii_PYR-1       R-------------------------
Mflv_2849|M.gilvum_PYR-GCK          STSSAPTH------------------
MAV_5246|M.avium_104                IPGA----------------------
TH_4361|M.thermoresistible__bu      R-------------------------
MAB_3984c|M.abscessus_ATCC_199      --------------------------
MLBr_02000|M.leprae_Br4923          QTSD----------------------
Mb0994|M.bovis_AF2122/97            GRTA----------------------
Rv0969|M.tuberculosis_H37Rv         GRTA----------------------
MUL_0423|M.ulcerans_Agy99           V-------------------------
MMAR_1448|M.marinum_M               PLPPAEAPTTEPRVETVTAQSESGDR