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TKSTILDVHGLNWASSTAVVEATLLRRPGVTSVEANAVNQTATVVYDPTTTSVADLAGWIRDCGFHCAGR SVPDHVCDPMSEPHHHPSATLDEQPTSAPSPTAGEVHAHEAAPARTPQEAMGHGGGHAGMSMDHMVRDMR NRFLVALALSIPIMLWSPMGRDMFGFTVPAPFGLRDDVFTLLLSLPVVFYSAWIFFDGAWRALRARTLDM MVLVAVAVGAGWLYSLGVTLTGGGEVFYEAASVLTAFVLLGHWFEMRARGGANDAIRTLLELAPPVAVVL RDGEPVETPTAEVAVGDLLLIRPGAKIPVDGTVAEGTSDVDESMVTGESLPVSKAPDSKVIGASINTTGT LRVLATKVGSDTVLAQIVAMVQEAQNSKAPGQRFADRAAFWLVLVALIGGTATFLVWWAVGAGVQTALLF AITVVVITCPDALGLATPTAIMVGTGLGAKRGVLFKNATALETSARIDTVVMDKTGTLTKGEPEVTDVVV DGIPEDQVLAMVAAVETESEHPLAGAIVRYAAAHGIASASLTGFRNVPGHGAVATVDGRRVAVGNRKLMV EEDVEFGVLMQRRDELAASGRTAVLVGVDGRGVGVIALADAVRETSAEAVSALHDLGVEVVMLSGDNQAT ADRIAAQLGIDTVIAEVLPGDKAAKIAELQRQGKKVAMVGDGVNDAPALAQADLGVAIGAGTDVAIETAD LVLMRSDPLDVAIALQIGRGTLRKMRQNLGWAVGYNVIALPIAAGVFVPSLGLVLRPEIAALSMSGSSFI VAVNALMLKRLKLPVPASAEAGAKS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3678 | - | - | 100% (796) | copper-translocating P-type ATPase |
| M. vanbaalenii PYR-1 | Mvan_5853 | - | 0.0 | 82.07% (792) | heavy metal translocating P-type ATPase |
| M. vanbaalenii PYR-1 | Mvan_4449 | - | e-135 | 43.44% (663) | heavy metal translocating P-type ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0994 | ctpV | 1e-145 | 46.63% (652) | metal cation transporter P-type ATPase CtpV |
| M. gilvum PYR-GCK | Mflv_2852 | - | 1e-143 | 44.70% (689) | copper-translocating P-type ATPase |
| M. tuberculosis H37Rv | Rv0969 | ctpV | 1e-146 | 46.78% (652) | metal cation transporter P-type ATPase CtpV |
| M. leprae Br4923 | MLBr_01987 | ctpA | 1e-114 | 39.16% (669) | putative cation-transporting ATPase |
| M. abscessus ATCC 19977 | MAB_0449 | - | 1e-132 | 43.45% (649) | copper-transporting ATPase |
| M. marinum M | MMAR_1448 | - | 1e-158 | 44.16% (745) | zinc cation transport ATPase |
| M. avium 104 | MAV_5246 | - | 1e-121 | 39.77% (684) | copper-translocating P-type ATPase |
| M. smegmatis MC2 155 | MSMEG_5014 | - | 1e-138 | 42.40% (691) | copper-translocating P-type ATPase |
| M. thermoresistible (build 8) | TH_2531 | - | 1e-138 | 43.29% (700) | PUTATIVE copper-translocating P-type ATPase |
| M. ulcerans Agy99 | MUL_0423 | ctpV | 1e-144 | 48.08% (599) | metal cation transporter p-type ATPase, CtpV |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0994|M.bovis_AF2122/97 ----------------MRVCVTGFNVDAVRAVAIEETVSQVTGVHAVHAY
Rv0969|M.tuberculosis_H37Rv ----------------MRVCVTGFNVDAVRAVAIEETVSQVTGVHAVHAY
MUL_0423|M.ulcerans_Agy99 ----------------MRVHANGFAIDATRAAAIEESVGRVGGVRAVRAY
MAV_5246|M.avium_104 ------------------MSTPPRHIDEGTFPDHTASTARIELEITGMTC
MSMEG_5014|M.smegmatis_MC2_155 ---------------------------------MTTATGHVELQIGGMTC
MLBr_01987|M.leprae_Br4923 ---------------------------------MRAPNGWNNLP------
MMAR_1448|M.marinum_M MSSVDVIVPVGAALVIAGLAWYFFAPRRAHAASLSEGVQRILVTIRGGYS
Mflv_2852|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0449|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2531|M.thermoresistible__bu --------------------------------------------------
Mvan_3678|M.vanbaalenii_PYR-1 -------MTKSTILDVHGLNWASSTAVVEATLLRRPGVTSVEANAVNQTA
Mb0994|M.bovis_AF2122/97 PRTASV-------VIWYSPELGDTAAVLSAITKAQHVPAELVPARAPHSA
Rv0969|M.tuberculosis_H37Rv PRTASV-------VIWYSPELGDTAAVLSAITKAQHVPAELVPARAPHSA
MUL_0423|M.ulcerans_Agy99 PRTASV-------VIWYSPAHCDTAAIVSAIAEAEHAGDASAPAPAARVA
MAV_5246|M.avium_104 ASCAAR-------IEKKLNKLDGVTATVNYATEKAAVSAPASYDPQTLIT
MSMEG_5014|M.smegmatis_MC2_155 ASCAAR-------IERKLNKLDGVTASVNYATEKASVEVAGEVSPETLIE
MLBr_01987|M.leprae_Br4923 ------------------NKLSDFSTLVNSATRVAAINLSEVTQTAEVCE
MMAR_1448|M.marinum_M PNVVQVRQGAPVEIEFDRQESGDCSSRVVFPDLHLSAALPAHQRTTVRFT
Mflv_2852|M.gilvum_PYR-GCK -----------------------------MTNHDEHAIAASHTGVHADHD
MAB_0449|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2531|M.thermoresistible__bu ------------------------------------MVGPAHHGTVAADG
Mvan_3678|M.vanbaalenii_PYR-1 TVVYDPTTTSVADLAGWIRDCGFHCAGRSVPDHVCDPMSEPHHHPSATLD
Mb0994|M.bovis_AF2122/97 GVRGVGVVRKITGGIRRMLS----------------RPPGVDKPLKASRC
Rv0969|M.tuberculosis_H37Rv GVRGVGVVRKITGGIRRMLS----------------RPPGVDKPLKASRC
MUL_0423|M.ulcerans_Agy99 GIADGGVVGRVIGGLARALLGMRTDDNDD------DPPPEIARLRAALDR
MAV_5246|M.avium_104 EIENAGYAAAVAT-------------------------------------
MSMEG_5014|M.smegmatis_MC2_155 VVETAGYTAHLPA-------------------------------------
MLBr_01987|M.leprae_Br4923 AVRRAALCTDGGE-------------------------------------
MMAR_1448|M.marinum_M PQQAGSFGFFCSMNMINGTLVVTPDGQAAGSAEPEQPNASIGYAATNSGD
Mflv_2852|M.gilvum_PYR-GCK DQGEHAVQDTN-------------------------------------VH
MAB_0449|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2531|M.thermoresistible__bu -----RAQHLT-------------------------------------GR
Mvan_3678|M.vanbaalenii_PYR-1 EQPTSAPSPTAGEVHAHEAA-------------------------PARTP
Mb0994|M.bovis_AF2122/97 GGRPRGPVRGSASWPGEQNRRERRTWLPRVWLALPLGLLALGSSMFFG--
Rv0969|M.tuberculosis_H37Rv GGRPRGPVRGSASWPGEQNRRERRTWLPRVWLALPLGLLALGSSMFFG--
MUL_0423|M.ulcerans_Agy99 IGYSPEQDTATQLSPSEQARSGIRFWSRRAWLAWPLGLLASGLTMFFG--
MAV_5246|M.avium_104 -PSPPRD-----DPE---LASLRRRLVTAIALAGP----VIAVAMIPAL-
MSMEG_5014|M.smegmatis_MC2_155 -PPQPETGGTEQDPEDRATDALRTRLLVSAVLTVP----VIAMAMVPAL-
MLBr_01987|M.leprae_Br4923 -ALQRRQ----ADADN--ARYLLIRLAVAAALFVPLAHLSVMFAVLPST-
MMAR_1448|M.marinum_M EPAAAEIEAAQAQERRAEITDLSRRVAFGAVLSAPVLYAVMAQPLGAGWV
Mflv_2852|M.gilvum_PYR-GCK HDNRGDHGGHAGHGADHVAVFRK-LFWINLIIAIPVIAFSTMFAMLLGYE
MAB_0449|M.abscessus_ATCC_1997 ----------------------------MLVVAVPVVVFDPMFAMLLGYQ
TH_2531|M.thermoresistible__bu DHHRHGHGDHAG----HVAEFRR-LFWVMLLLAVPTVAFSGMFAMILGYQ
Mvan_3678|M.vanbaalenii_PYR-1 QEAMGHGGGHAGMSMDHMVRDMRNRFLVALALSIPIMLWSPMGRDMFGFT
: * .
Mb0994|M.bovis_AF2122/97 --AYPWAG--WLAFAATLPVQFVAGWPILRGAVQQARALTSNMDTLIALG
Rv0969|M.tuberculosis_H37Rv --AYPWAG--WLAFAATLPVQFVAGWPILRGAVQQARALTSNMDTLIALG
MUL_0423|M.ulcerans_Agy99 --AYPWAG--WLAFAATIPVQFIAGWPFLVGAVQQARARSANMNTLISLG
MAV_5246|M.avium_104 --QFQHWH--WAALALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIG
MSMEG_5014|M.smegmatis_MC2_155 --QFTNWQ--WLSLTLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMG
MLBr_01987|M.leprae_Br4923 --HFPGWE--WMLTALAIPVVTWAAWPFHRVAIHNARYHGASMETLISTG
MMAR_1448|M.marinum_M P-AVLLHH--WLQLALITPVMFYVGWPIHRTGWLALAHRSADMNSLITLG
Mflv_2852|M.gilvum_PYR-GCK VPDVPGGR--WIAPLLGTVMYVVGGRPFLTGAVSEIRSRKPGMMLLIGLA
MAB_0449|M.abscessus_ATCC_1997 LPDAGWAR--WVFPVLGTVVYLWGGKPFLVGAVSEIRSRTPGMMLLIGLA
TH_2531|M.thermoresistible__bu VPRVPGAQ--WVSPVLGTVMYVWGGRPFLTGAISEIRSRTPGMMLLIGLA
Mvan_3678|M.vanbaalenii_PYR-1 VPAPFGLRDDVFTLLLSLPVVFYSAWIFFDGAWRALRARTLDMMVLVAVA
: . : . * *: .
Mb0994|M.bovis_AF2122/97 TLTAFVYSTYQLFAGGP---------------------------LFFDTS
Rv0969|M.tuberculosis_H37Rv TLTAFVYSTYQLFAGGP---------------------------LFFDTS
MUL_0423|M.ulcerans_Agy99 TLTAFIYSTYQLFAGGP---------------------------LFFDTA
MAV_5246|M.avium_104 TLAAFLWSLYALVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVA
MSMEG_5014|M.smegmatis_MC2_155 TLAAFGWSLYALFWGTAGVPGMTHPFSLVG------SRTDGAGNIYLEVA
MLBr_01987|M.leprae_Br4923 ITAATIWSLYTVFGHHQSTEHRGVWRALLG-----------SDAIYFEVA
MMAR_1448|M.marinum_M TFAAYGYSLLVTAASTALPAELQD--------------------VYYEAV
Mflv_2852|M.gilvum_PYR-GCK ITVAFFASWGASLGVLHHEL------------------------EFWWEL
MAB_0449|M.abscessus_ATCC_1997 ITVAFTASWGASIGVLDHQL------------------------SFWWEL
TH_2531|M.thermoresistible__bu LTVAFLSSWGASLGVLDHRL------------------------EFWWEL
Mvan_3678|M.vanbaalenii_PYR-1 VGAGWLYSLGVTL--TGGGE------------------------VFYEAA
.. * :
Mb0994|M.bovis_AF2122/97 ALIIAFVVLGRHLEARATGKASEAISKLLELGAKEATLLV----DGQELL
Rv0969|M.tuberculosis_H37Rv ALIIAFVVLGRHLEARATGKASEAISKLLELGAKEATLLV----DGQELL
MUL_0423|M.ulcerans_Agy99 ALIIAFVVLGRYFEATAHGKTREAISKLLDMGAKETRLIV----DGEEHL
MAV_5246|M.avium_104 AGVTLFVLAGRYFERRSKRTAGAALRALLALGAKDVAVLR----AGAETR
MSMEG_5014|M.smegmatis_MC2_155 AGVTTFILAGRYFEAKSKRRASAALRALMELGAKDVAILR----NGAEQR
MLBr_01987|M.leprae_Br4923 AGITVFVLAGKYYTARAKSHASIALLALAALSAKDAAVLQP---DGSEMV
MMAR_1448|M.marinum_M GVILTLIMLGRLLEARAKAGTGEAIRALLGLQARTARVIR----NGTQAE
Mflv_2852|M.gilvum_PYR-GCK ALLIVIMLLGHWFEMRSLAQTTSALDSLAALLPDEAEKVD----GDRIIT
MAB_0449|M.abscessus_ATCC_1997 ALLVVIMLAGHWIEMRSLAQTTSALDSLAALLPDTAERVQ----GQQVVT
TH_2531|M.thermoresistible__bu ALLIVIMLLGHWIELRSLARTTSALDSLAALLPDTAERVEQGPDGETVTV
Mvan_3678|M.vanbaalenii_PYR-1 SVLTAFVLLGHWFEMRARGGANDAIRTLLELAPPVAVVLR----DGEPVE
. : ::: *: : : *: * : . . :
Mb0994|M.bovis_AF2122/97 VPVDQVQVGDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAG
Rv0969|M.tuberculosis_H37Rv VPVDQVQVGDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAG
MUL_0423|M.ulcerans_Agy99 VPVDRVQVGDLVRVRPGEKIPVDGEVIDGRAAVDESMLTGESVPVEKGVG
MAV_5246|M.avium_104 IPIERLAVGDEFVVRPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVG
MSMEG_5014|M.smegmatis_MC2_155 IPIDQLGVGDEFVVRPGEKIATDGVVVDGSSAVDASMLTGESVPVEVGPG
MLBr_01987|M.leprae_Br4923 IPANELNEQQRFVVRPGQTIAADGLVIDGSATVSMSPITGEAKPVRVNPG
MMAR_1448|M.marinum_M IPVDEVVVGDDILVRPGEKIAVDATVVSGQSTVDESMVTGESMPVTKHTG
Mflv_2852|M.gilvum_PYR-GCK VSPADLQVGDLVVVRPGGSVPADGRIVEGRADMDESMVTGESRPVARGVG
MAB_0449|M.abscessus_ATCC_1997 VPLADLRVGDIVVVRPGGSVPADGRVVEGSASLDESMVTGESAPVRRGVG
TH_2531|M.thermoresistible__bu VAPADLRVGDTVIVRPGAGIPADGRIIDGVADVDESMVTGESVPVRRGVG
Mvan_3678|M.vanbaalenii_PYR-1 TPTAEVAVGDLLLIRPGAKIPVDGTVAEGTSDVDESMVTGESLPVSKAPD
. : : . :*** :..*. : * : :. : :***: ** .
Mb0994|M.bovis_AF2122/97 DRVAGATVNLDGLLTVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADR
Rv0969|M.tuberculosis_H37Rv DRVAGATVNLDGLLTVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADR
MUL_0423|M.ulcerans_Agy99 DWVAGATVNTDGLLTVRATAVGADTALAQIVRLVEEAQGGKAPVQRLADR
MAV_5246|M.avium_104 DGVTGGTVNAGGRLVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADR
MSMEG_5014|M.smegmatis_MC2_155 DQVVGATVNVGGRLVVRANRIGSDTQLAQMARLVEDAQSGKAQAQRLADR
MLBr_01987|M.leprae_Br4923 AQVIGGTVVLNGRLIVEAAAVGDETQLAGMVRLVEQAQQQNANAQRLADR
MMAR_1448|M.marinum_M DTVIGATVNTTGSLRIRAAKVGADTMLAQIIGMVQQAQASRAPIQRLADA
Mflv_2852|M.gilvum_PYR-GCK DAVTAGTVATDSGLRVEITATGDDTALAGIQRLVTEAQNSSSRAQRLADR
MAB_0449|M.abscessus_ATCC_1997 EQVVAGTVATDSGLRVQVSAVGADTALAGIQRLVADAQASTSRAQRVADT
TH_2531|M.thermoresistible__bu DRVVAATVATDSGLRITVTAVGDDTALAGIRRMVAEAQSSSSRAQRIADT
Mvan_3678|M.vanbaalenii_PYR-1 SKVIGASINTTGTLRVLATKVGSDTVLAQIVAMVQEAQNSKAPGQRFADR
* ..:: . * : * :* ** : :* ** : **.**
Mb0994|M.bovis_AF2122/97 VSAVFVPAVIGVAVATFAGWTLIAAN--PVAGMTAAVAVLIIACPCALGL
Rv0969|M.tuberculosis_H37Rv VSAVFVPAVIGVAVATFAGWTLIAAN--PVAGMTAAVAVLIIACPCALGL
MUL_0423|M.ulcerans_Agy99 VSAVFVPVVVRIAAATFAGWTLLAAN--PVAGMTAAVSVLIIACPYALGL
MAV_5246|M.avium_104 VSGVFVPVVLLLAVATLAGWLAAGGT--LATALTAAVAVLIIACPCALGL
MSMEG_5014|M.smegmatis_MC2_155 VSAVFVPIVIALAVATLGFWLGTGGS--VAAAFTAAVAVLIIACPCALGL
MLBr_01987|M.leprae_Br4923 IASVFVPCVFAVAALTAVGWLIAGSG--PDRVFSAAIAVLVIACPCALGL
MMAR_1448|M.marinum_M ISAYFVPVVIAIAIATFAVWFVAGPTPELTQALVSAVAVLIIACPCALGL
Mflv_2852|M.gilvum_PYR-GCK AAGWLFWFALGTAAITAVAWSIVGD---PDASVIRAITVLVIACPHALGL
MAB_0449|M.abscessus_ATCC_1997 AAGWLFWFALAAAIITAVTWTALGH---PDAAVVRAITVLVIACPHALGL
TH_2531|M.thermoresistible__bu AAGWLFWFALGAALLTALVWAVLHR---PDFAVVRTITVLVIACPHALGL
Mvan_3678|M.vanbaalenii_PYR-1 AAFWLVLVALIGGTATFLVWWAVGAG--VQTALLFAITVVVITCPDALGL
: :. .. . * * . :::*::*:** ****
Mb0994|M.bovis_AF2122/97 ATPTAIMVGTGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRV
Rv0969|M.tuberculosis_H37Rv ATPTAIMVGTGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRV
MUL_0423|M.ulcerans_Agy99 ATPTAIIVGTGRGADMGILVKGGEVLEASKKIDTVVFDKTGTLTRAQMEL
MAV_5246|M.avium_104 ATPTALLVGTGRAAQLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTV
MSMEG_5014|M.smegmatis_MC2_155 ATPTALLVGTGRGAQLGILIKGPEVLESTRRVDTIVLDKTGTITTGSMTL
MLBr_01987|M.leprae_Br4923 ATPTAMMVASGRGAQLGILLKGHESFEATRAVDTVVFDKTGTLTTGQLKV
MMAR_1448|M.marinum_M ATPLSIMVGTGKGARAGILIRSAEALETAHKLDTIVLDKTGTVTAGRPAL
Mflv_2852|M.gilvum_PYR-GCK AIPLVVSIATERAARGGVLIKDRLALEGMRTVDAVLFDKTGTLTKGEPTV
MAB_0449|M.abscessus_ATCC_1997 AIPLVVSIATERAARGGVLVKDRLALEQMRTVDVVLFDKTGTLTKGTPTL
TH_2531|M.thermoresistible__bu AIPLVVAIATERAARGGVLIKDRIALENMRTVDVVLFDKTGTLTKGQPAV
Mvan_3678|M.vanbaalenii_PYR-1 ATPTAIMVGTGLGAKRGVLFKNATALETSARIDTVVMDKTGTLTKGEPEV
* * : :.: .* *:*.:. :* :*.:::*****:* . :
Mb0994|M.bovis_AF2122/97 TDVIAGQRRQPNQVLRLAAAVESGSEHPIGAAIVAAAHERGLAIPAANAF
Rv0969|M.tuberculosis_H37Rv TDVIAGQRRQPDQVLRLAAAVESGSEHPIGAAIVAAAHERGLAIPAANAF
MUL_0423|M.ulcerans_Agy99 TDVIAGKRRQPDVVLRIAAAVESGSEHPIGAAIVAGARERELEVPPATEF
MAV_5246|M.avium_104 LDVVAADGTDRATLLRYAGALEAASEHPIAHAIARDAKAELGPLPTPTGF
MSMEG_5014|M.smegmatis_MC2_155 LDVVVADGEDRDDVLRVAAAVEDASEHPIARAIAAGARERTGELPAVEGF
MLBr_01987|M.leprae_Br4923 SAVTAAPGWQANEVLQMAATVESASEHAVALAIAASTTHR----EPVANF
MMAR_1448|M.marinum_M TDVEVTGTLQQNELLALVAAAEANSEHPVATAVLAGSRDRGIDHSAADDF
Mflv_2852|M.gilvum_PYR-GCK TAIEVRGDLDDDFVLALAAAAEADSEHPLARAIVKAADERGLTVPRAKGF
MAB_0449|M.abscessus_ATCC_1997 TGIEAAPGHDGDAVLALAAAAETDSEHPLARAIVAAARQRGLDIPAASGF
TH_2531|M.thermoresistible__bu TGITAAGAHSEEDVLRLAAAAEAPSEHPLARALVAAAQRHGTDLPPATDF
Mvan_3678|M.vanbaalenii_PYR-1 TDVVVDG-IPEDQVLAMVAAVETESEHPLAGAIVRYAAAHGIASASLTGF
: . :* ..: * ***.:. *: : . *
Mb0994|M.bovis_AF2122/97 TAVAGHGVRAQVNGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTA
Rv0969|M.tuberculosis_H37Rv TAVAGHGVRAQVNGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTA
MUL_0423|M.ulcerans_Agy99 TNLAGHGVRGEVGGKSVLVGRRKLVDEQHLRLPEQLAAAAADLEERGRTA
MAV_5246|M.avium_104 RAVGGGGVHGRVDGHAVAIGRPSWLAERGLRPDAALAAAAARAEHDGKTV
MSMEG_5014|M.smegmatis_MC2_155 ANIEGLGVQGTVEGRAVVVGRPRLFGDPEKSLPRKLADAMEAAQAQGRTA
MLBr_01987|M.leprae_Br4923 RAVPGHGVSGTVAERAVRVGKPSWIASR--CNSTTLVTARRNAELRGETA
MMAR_1448|M.marinum_M ASITGKGVRATVAGRTVLVGTATLLAENN-VTTSELERIGADLAAKGKTP
Mflv_2852|M.gilvum_PYR-GCK SSSPAVGVTATVDGHEIRVGGPRLLEEIG-AQE---VHAATSWRDEGAII
MAB_0449|M.abscessus_ATCC_1997 TSEPALGVSAQVAETRVQVGGPALLDARG-SRE---LAVAAQWRTEGAII
TH_2531|M.thermoresistible__bu ASTPGLGVRARVAGRTVRVGGPRLLAETG-QTA---PAGSEGWRARGSTV
Mvan_3678|M.vanbaalenii_PYR-1 RNVPGHGAVATVDGRRVAVGNRKLMVEED-VEFGVLMQRRDELAASGRTA
. *. . * : :* . *
Mb0994|M.bovis_AF2122/97 VFVGQDGQVVGVLAVADTVKDDAADVVGRLHAMGLQVAMITGDNARTAAA
Rv0969|M.tuberculosis_H37Rv VFVGQDGQVVGVLAVADTVKDDAADVVGRLHAMGLQVAMITGDNARTAAA
MUL_0423|M.ulcerans_Agy99 VYVGQDGQVVGVLAVADTVKDDAADVVSQLHAMGLQVALITGDNARTAAA
MAV_5246|M.avium_104 VAVGWDGRARGILALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARR
MSMEG_5014|M.smegmatis_MC2_155 VVVGWDGTARGVLVVADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARA
MLBr_01987|M.leprae_Br4923 VFVEIDGEQCGVIAVADAVKASAADAVAALHDRGFRTALLTGDNPASAAA
MMAR_1448|M.marinum_M ILAAVDGRPAGVLAVADTVKDDSMAAIAALGKLGLQVVMITGDNARTAKA
Mflv_2852|M.gilvum_PYR-GCK LHVIRDGAVVGGLRLADEIRPESRDAVDALHKLGVEVVMITGDAEAVAQA
MAB_0449|M.abscessus_ATCC_1997 LHVLLDGQVAAALRLADDIRPESADTVKALHKLGVRVVMITGDAQAVADT
TH_2531|M.thermoresistible__bu LYVLVDDMIAGAVALADEIRPESRPTVDALHRQGIDVALITGDARSVAES
Mvan_3678|M.vanbaalenii_PYR-1 VLVGVDGRGVGVIALADAVRETSAEAVSALHDLGVEVVMLSGDNQATADR
: . *. . : :** :: : .: : *. :::** *
Mb0994|M.bovis_AF2122/97 IAKQVGIEKVLAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQAD
Rv0969|M.tuberculosis_H37Rv IAKQVGIEKVLAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQAD
MUL_0423|M.ulcerans_Agy99 IAAQVGIDRVLAEVLPADKVNEVRRLQDEGRIVAMVGDGVNDAPALVQAD
MAV_5246|M.avium_104 TAGELGIGEVISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAAD
MSMEG_5014|M.smegmatis_MC2_155 IADQVGIDDVYAEVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQAD
MLBr_01987|M.leprae_Br4923 VASRIGIDEVIADILPEDKVDVIEQLRDRGHVVAMVGDGINDGPALARAD
MMAR_1448|M.marinum_M IARQVGVSRVLAEVLPEHKAGEIRRLQAEGRTVGMVGDGINDAPALAQAD
Mflv_2852|M.gilvum_PYR-GCK VGHELGIDRVFAGVRPEDKASKVAALQQEGKKVAMVGDGVNDAPALAQAD
MAB_0449|M.abscessus_ATCC_1997 VAGRLGVDRVFAQVRPQDKAAAVAQLQQEGHTVAMVGDGVNDAPALAQAD
TH_2531|M.thermoresistible__bu VAAELGIDRVLADVPPEHKAAKVVELQREGRRVAMVGDGVNDAPALARAD
Mvan_3678|M.vanbaalenii_PYR-1 IAAQLGIDTVIAEVLPGDKAAKIAELQRQGKKVAMVGDGVNDAPALAQAD
. .:*: * : * .*. : *: *: *.*****:**..**. **
Mb0994|M.bovis_AF2122/97 LGIAIGTGTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAF
Rv0969|M.tuberculosis_H37Rv LGIAIGTGTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAF
MUL_0423|M.ulcerans_Agy99 LGIAIGTGTDVAIEASDITLMSGRLDGVVSAIELSRRTLRTIYQNLGWAF
MAV_5246|M.avium_104 LGLAMGTGTDVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAF
MSMEG_5014|M.smegmatis_MC2_155 LGLSMGTGTDVAIEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAF
MLBr_01987|M.leprae_Br4923 LGMAIGRGTDVAIGAADIILVRDNLDVVPITLDLAAATMRTIKFNMVWAF
MMAR_1448|M.marinum_M VGLAIGTGTDVAIEAADITLISGSLAGVVTAIQLSRATMRNIRENLFFAL
Mflv_2852|M.gilvum_PYR-GCK VGIAIGAGTDVAIASAGVILASSDPRSVLSVIELSRASYRKMKQNLWWGA
MAB_0449|M.abscessus_ATCC_1997 VGIAIGAGTDVAIASAGVILASSDPRSVLSVIELSRASYRKMKQNLWWAA
TH_2531|M.thermoresistible__bu VGIAIGAGTDVAIASAGVVLAGSDPRSVLSVLQLSRAAYRKMKQNLWWAA
Mvan_3678|M.vanbaalenii_PYR-1 LGVAIGAGTDVAIETADLVLMRSDPLDVAIALQIGRGTLRKMRQNLGWAV
:*:::* ****** :..: : . . .: :. : .: *: :.
Mb0994|M.bovis_AF2122/97 GYNTAAIPLAA------LGA-LNPVVAGAAMGFSSVSVVTNSLRLRRFGR
Rv0969|M.tuberculosis_H37Rv GYNTAAIPLAA------LGA-LNPVVAGAAMGFSSVSVVTNSLRLRRFGR
MUL_0423|M.ulcerans_Agy99 GYNTAAIPLAA------LGV-LNPVVAGAAMGLSSVSVVTNSLRLRRFGR
MAV_5246|M.avium_104 GYNLAAIPLAA------LGM-LNPMLAGAAMALSSVLVVGNSLRLRSFAS
MSMEG_5014|M.smegmatis_MC2_155 AYNVAALPLAA------AGL-LNPMLAGAAMAFSSVFVVSNSLRLKRFR-
MLBr_01987|M.leprae_Br4923 GYNIAAIPIAA------AGL-LNPLVAGAAMAFSSFFVVSNSLRLRNFGA
MMAR_1448|M.marinum_M IYNAIGIPLAAGVLYPTLGLRLSPMIAAAAMALSSLSVVGNANRLRRYRV
Mflv_2852|M.gilvum_PYR-GCK GYNLIAVPLAAGVLAP-IGFVLPMSVGAILMSLSTIVVALNAQLLRRLDL
MAB_0449|M.abscessus_ATCC_1997 GYNLISVPLAAGVAAP-IGFVMPMSAGAVLMSLSTVVVALNSQLLRRLDL
TH_2531|M.thermoresistible__bu GYNLIAVPLAAGVLAP-AGFVMPMSVGAILMSLSTVVVALNAQLLRRLDL
Mvan_3678|M.vanbaalenii_PYR-1 GYNVIALPIAAGVFVPSLGLVLRPEIAALSMSGSSFIVAVNALMLKRLKL
** .:*:** * : .. *. *:. *. *: *:
Mb0994|M.bovis_AF2122/97 DGRTA---------------------------------------------
Rv0969|M.tuberculosis_H37Rv DGRTA---------------------------------------------
MUL_0423|M.ulcerans_Agy99 DV------------------------------------------------
MAV_5246|M.avium_104 IIPGA---------------------------------------------
MSMEG_5014|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01987|M.leprae_Br4923 ILSCGTSRHRTVKRWRCPPPTRLRSTACSPVDASPLRPVAHRTGVKPPTH
MMAR_1448|M.marinum_M EPLPPAEAPTTEPRVETVTAQSESGDR-----------------------
Mflv_2852|M.gilvum_PYR-GCK SPEASTRAVLNR--------------------------------------
MAB_0449|M.abscessus_ATCC_1997 RPQTSARNMLNS--------------------------------------
TH_2531|M.thermoresistible__bu RPEQSLAAARR---------------------------------------
Mvan_3678|M.vanbaalenii_PYR-1 PVPASAEAGAKS--------------------------------------
Mb0994|M.bovis_AF2122/97 -
Rv0969|M.tuberculosis_H37Rv -
MUL_0423|M.ulcerans_Agy99 -
MAV_5246|M.avium_104 -
MSMEG_5014|M.smegmatis_MC2_155 -
MLBr_01987|M.leprae_Br4923 R
MMAR_1448|M.marinum_M -
Mflv_2852|M.gilvum_PYR-GCK -
MAB_0449|M.abscessus_ATCC_1997 -
TH_2531|M.thermoresistible__bu -
Mvan_3678|M.vanbaalenii_PYR-1 -