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VEHAVEDLFRNSGGYATTAALLRVMSRQQLDVRVRKGELIRVWHGVYAATEPDYLGRLQALDSYIGQPAV ACMGTAAVLYGFDNEATSAVHILDPGVRVRPTVGLMVHQRVGAPLGRVRGRLATSPAWTAVEVARTLHRP RALATLDAALRTGLCTPVELHAAVTEQRGRRGIVAVRELLPLADARAESPMESEARLAMHDYGVPRPELQ YVVHGAWDSWRVDFAWPEVLVAAEYESVDWHTGRDAMLKDKARFAGLQHAAWTVIPITVTDVRISPERLA ERIKEHLWRAAHTASSHKLAL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5457 | - | - | 100% (301) | hypothetical protein Mvan_5457 |
| M. vanbaalenii PYR-1 | Mvan_3817 | - | 1e-77 | 52.26% (287) | hypothetical protein Mvan_3817 |
| M. vanbaalenii PYR-1 | Mvan_5526 | - | 7e-19 | 33.06% (248) | hypothetical protein Mvan_5526 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2272 | - | 1e-102 | 68.54% (267) | hypothetical protein Mb2272 |
| M. gilvum PYR-GCK | Mflv_1335 | - | 1e-119 | 73.26% (288) | hypothetical protein Mflv_1335 |
| M. tuberculosis H37Rv | Rv2248 | - | 1e-102 | 68.91% (267) | hypothetical protein Rv2248 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3617 | - | 3e-68 | 48.25% (286) | hypothetical protein MAB_3617 |
| M. marinum M | MMAR_3341 | - | 1e-111 | 69.61% (283) | hypothetical protein MMAR_3341 |
| M. avium 104 | MAV_3234 | - | 2e-22 | 30.91% (275) | hypothetical protein MAV_3234 |
| M. smegmatis MC2 155 | MSMEG_1733 | - | 6e-68 | 48.95% (286) | hypothetical protein MSMEG_1733 |
| M. thermoresistible (build 8) | TH_1835 | - | 4e-27 | 54.87% (113) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1301 | - | 1e-103 | 68.05% (266) | hypothetical protein MUL_1301 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5457|M.vanbaalenii_PYR-1 MEHAVEDLFRNSGGYATTAALLRVMSRQQLDVRVRKGELIRVWHGVYAA-
Mflv_1335|M.gilvum_PYR-GCK MRKVLDEVLRRCNGYATTAALLDVMSRQQLDGLVRRRELVRVWHGVYAV-
Mb2272|M.bovis_AF2122/97 ------------------------MTRQQLDVQVKNGGLVRVWYGVYAA-
Rv2248|M.tuberculosis_H37Rv ------------------------MTRQQLDVQVKNGGLVRVWYGVYAA-
MMAR_3341|M.marinum_M MPTDAQALLQKSGGFATTAQLLTVMTRQQLDVRVRNGSLVRVWHGVYAA-
MUL_1301|M.ulcerans_Agy99 ------------------------MTGQQLDVRVRNGSLVRVWHGVYAA-
MAB_3617|M.abscessus_ATCC_1997 MHPSIRALFHGRGAIR-AGELQEILSAKRISSLIRDGHLHRPWHGVYTL-
MSMEG_1733|M.smegmatis_MC2_155 MNPQLMRLFDDQRGVATSGQILGLITRYAFDQALKTGVLERIWPGIYCL-
TH_1835|M.thermoresistible__bu --------------------------------------------------
MAV_3234|M.avium_104 -------------------MGTEALSAGALTERDLRRSCTRIYRNVYQRG
Mvan_5457|M.vanbaalenii_PYR-1 TEPDYLGRLQALDSYIGQPAVACMGTAAVLYGFDNEATSAVHILDPG-VR
Mflv_1335|M.gilvum_PYR-GCK AQPDSRGRLNSLDAFLGQHAVACLGTAASLYGFDTEATETVHILDPG-AR
Mb2272|M.bovis_AF2122/97 QEPDLLGRLAALDVFMGGHAVACLGTAAALYGFDTENTVAIHMLDPG-VR
Rv2248|M.tuberculosis_H37Rv QEPDLLGRLAALDVFMGGHAVACLGTAAALYGFDTENTVAIHMLDPG-VR
MMAR_3341|M.marinum_M EEPNLLGRLTALDVFMGRPVVACMGTAATLYGFDTECSSAVHVLDPG-VR
MUL_1301|M.ulcerans_Agy99 EEPNLLGRLTALDVFMGRPVVACMGTAATLYGFDTECSSAVHVLDPG-VR
MAB_3617|M.abscessus_ATCC_1997 PNPTVEIQLRALDLVADAHVPVCMGTAAASYGFDTERDGALHVINPVPGQ
MSMEG_1733|M.smegmatis_MC2_155 GEPTEPLLLRGLDLSAGTRVAACLTTAAALHGFDTEGSTDLHVLNPPRHQ
TH_1835|M.thermoresistible__bu --------------------------------------------------
MAV_3234|M.avium_104 ADFTASDRAIAAWLWSGRRAVVAGNSAAALLGAQWVDPRAPAELITDRKR
Mvan_5457|M.vanbaalenii_PYR-1 VRPTVGLMVHQRVGAPLGRVRG----RLATSPAWTAVEVARTLHRPRALA
Mflv_1335|M.gilvum_PYR-GCK VRPVDGLMVHQRVGAPLRRVDG----RLATAPAWTAVEVARVLPRPRALA
Mb2272|M.bovis_AF2122/97 MRPTVGLMVHQRVGARLQRVSG----RLATAPAWTAVEVARQLRRPRALA
Rv2248|M.tuberculosis_H37Rv MRPTVGLMVHQRVGARLQRVSG----RLATAPAWTAVEVARQLRRPRALA
MMAR_3341|M.marinum_M MRPTVGLMVHQRIGARLQRVAG----RLATAPAWTAVEVARALRRPRALA
MUL_1301|M.ulcerans_Agy99 MRPTIGLMVHQRIGARLQRVAG----QLATAPPWTAAEVARALRRPRALA
MAB_3617|M.abscessus_ATCC_1997 LRPRPNLVVHQRLGAPLRYVDG----RLTTAPDWTAIEIARTLRPSRAIG
MSMEG_1733|M.smegmatis_MC2_155 LRSVDGLVVHRREGAPLTVIDVDGDVRYVTAPAWTAVEVARALRRPRALA
TH_1835|M.thermoresistible__bu --------------------------------------------------
MAV_3234|M.avium_104 PPPLIVARNETLLPDEITEVRG----VPVTTPARTAYDLGRRPGLVAAVI
Mvan_5457|M.vanbaalenii_PYR-1 TLDAALRTGLCTPVELHAAVTEQRGRRGIVAVRELLPLADARAESPMESE
Mflv_1335|M.gilvum_PYR-GCK TLDAALHSGLCTAVELGAAAHEQRGRRGIVKVRELLAIADGRAESPMESE
Mb2272|M.bovis_AF2122/97 TLEAALRSMRCARSEIENAVAEQRGRRGIVAARELLPFADGRAESAMESE
Rv2248|M.tuberculosis_H37Rv TLDAALRSMRCARSEIENAVAEQRGRRGIVAARELLPFADGRAESAMESE
MMAR_3341|M.marinum_M TLDAALRSMQCTRDQIESAVAEQHGRRGIVAVRELLPLADPRAESAMESE
MUL_1301|M.ulcerans_Agy99 TLDAALRSMQCTRDQIESAVAEQHGRRGIVAVRELLPLADPRAESAMESE
MAB_3617|M.abscessus_ATCC_1997 TLDAALRSGHCSPGGLRHAARMQAGRRGIVHVRGLLTHADGRSESPMESE
MSMEG_1733|M.smegmatis_MC2_155 TLDAALRSGKCTRADVWRAALDQAGRRGIVAVRNLIALADPRAESPMESE
TH_1835|M.thermoresistible__bu ----------------------------------LIAIADGRAESPMESE
MAV_3234|M.avium_104 AIDSLARATGLTTECVEPLMRAHRGARGVRQLRRVLPLIDAGAESPQETR
::. * :**. *:.
Mvan_5457|M.vanbaalenii_PYR-1 ARLAMHDYGVPRPELQYVVH-GAWDS-WRVDFAWPEVLVAAEYESVDWHT
Mflv_1335|M.gilvum_PYR-GCK ARLVMHDHDLPRPELQYVID-GTHDDMWRVDFAWPEHHVAAEYDSMDWHS
Mb2272|M.bovis_AF2122/97 ARLVMIDHGLPLPELQYPIH-GHGGEMWRVDFAWPDMRLAAEYESIEWHA
Rv2248|M.tuberculosis_H37Rv ARLVMIDHGLPLPELQYPIH-GHGGEMWRVDFAWPDMRLAAEYESIEWHA
MMAR_3341|M.marinum_M TRLVMIDGGLARPELQYLIH-GSDGELWRVDFAWPDLRLAAEYDSIDWHA
MUL_1301|M.ulcerans_Agy99 TRLVMIDGGLARPELQYLIH-GSDGELWRVDFAWPDLRLAAEYDSIDWHA
MAB_3617|M.abscessus_ATCC_1997 TRLLFIDSGVPAPELQATIC-DRYGTVWRVDFLWRSARLIGEYDSDEWHS
MSMEG_1733|M.smegmatis_MC2_155 ARLMMLDAGLPAPELQHEVI-DGMGKLRRLDFAWPECRVAVEYDGDDWHG
TH_1835|M.thermoresistible__bu ARLAMIDGGLPIPELQYELR-DGAGRLRRVDFAWPRHRVAVEYDGVDWHS
MAV_3234|M.avium_104 TRLAIVGAGLPKPSTQITVHNDWGFVLARIDLGWEQWRVGVEYDGAQHWT
:** : . .:. *. * : . *:*: * : **:. :
Mvan_5457|M.vanbaalenii_PYR-1 GRDAMLKDKARFAGLQHAAWTVIPITVTDVRISPERLAERIKEHLWRAAH
Mflv_1335|M.gilvum_PYR-GCK GRVAMLRDRARYAGIQHARWTVIPIVVTDVRVHPARLAARIADHLLRAAS
Mb2272|M.bovis_AF2122/97 GPAEMLRDKTRWAKLQELGWTIVPIVVDDVRREPGRLAARIARHLDRARM
Rv2248|M.tuberculosis_H37Rv GPAEMLRDKTRWAKLQELGWTIVPIVVDDVRREPGRLAARIARHLDRARM
MMAR_3341|M.marinum_M GRVEMLRDKTRWAKIQDLGWTIIPIVVDDVRREPGRLVQRIGNHLDRLRA
MUL_1301|M.ulcerans_Agy99 GRVEMLRDKTRWAKIQDLGWTIIPIVVDDVRREPGRLVQRIGNHLDRLRA
MAB_3617|M.abscessus_ATCC_1997 GPAAMRKDKLKTARLQECGWTVIPITVDDIRRHRDELVARINTHLRHHAA
MSMEG_1733|M.smegmatis_MC2_155 NPDALRNDRVRAAALSDVGWLVIAIVSEDVRLRPQETVGRIDRQLGLARA
TH_1835|M.thermoresistible__bu GPDAMRRDRDRTAALMDVGWTVIAIVLEDVRYRTREFVGRVDAQLRRAQA
MAV_3234|M.avium_104 DPRIRAKDIDRVAELERRGWRIIRVSADLLRNRPDVLVGRIREALCAAGC
. .* : * : * :: : :* . *: *
Mvan_5457|M.vanbaalenii_PYR-1 TASSHKLAL
Mflv_1335|M.gilvum_PYR-GCK ---------
Mb2272|M.bovis_AF2122/97 AG-------
Rv2248|M.tuberculosis_H37Rv AG-------
MMAR_3341|M.marinum_M AS-------
MUL_1301|M.ulcerans_Agy99 AS-------
MAB_3617|M.abscessus_ATCC_1997 ---------
MSMEG_1733|M.smegmatis_MC2_155 A--------
TH_1835|M.thermoresistible__bu A--------
MAV_3234|M.avium_104 PL-------