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MHPSIRALFHGRGAIRAGELQEILSAKRISSLIRDGHLHRPWHGVYTLPNPTVEIQLRALDLVADAHVPV CMGTAAASYGFDTERDGALHVINPVPGQLRPRPNLVVHQRLGAPLRYVDGRLTTAPDWTAIEIARTLRPS RAIGTLDAALRSGHCSPGGLRHAARMQAGRRGIVHVRGLLTHADGRSESPMESETRLLFIDSGVPAPELQ ATICDRYGTVWRVDFLWRSARLIGEYDSDEWHSGPAAMRKDKLKTARLQECGWTVIPITVDDIRRHRDEL VARINTHLRHHAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3617 | - | - | 100% (293) | hypothetical protein MAB_3617 |
| M. abscessus ATCC 19977 | MAB_1200 | - | 1e-19 | 28.41% (176) | hypothetical protein MAB_1200 |
| M. abscessus ATCC 19977 | MAB_4161 | - | 5e-19 | 30.77% (169) | hypothetical protein MAB_4161 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2272 | - | 2e-73 | 51.32% (265) | hypothetical protein Mb2272 |
| M. gilvum PYR-GCK | Mflv_1335 | - | 1e-71 | 49.11% (281) | hypothetical protein Mflv_1335 |
| M. tuberculosis H37Rv | Rv2248 | - | 6e-74 | 51.70% (265) | hypothetical protein Rv2248 |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3341 | - | 3e-72 | 50.36% (276) | hypothetical protein MMAR_3341 |
| M. avium 104 | MAV_1002 | - | 7e-21 | 31.40% (172) | hypothetical protein MAV_1002 |
| M. smegmatis MC2 155 | MSMEG_1733 | - | 8e-71 | 47.44% (293) | hypothetical protein MSMEG_1733 |
| M. thermoresistible (build 8) | TH_1835 | - | 1e-28 | 51.30% (115) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1301 | - | 1e-70 | 51.32% (265) | hypothetical protein MUL_1301 |
| M. vanbaalenii PYR-1 | Mvan_5457 | - | 3e-68 | 48.25% (286) | hypothetical protein Mvan_5457 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1335|M.gilvum_PYR-GCK MRKVLDEVLRRCNGYATTAALLDVMSRQQLDGLVRRRELVRVWHGVYAVA
Mvan_5457|M.vanbaalenii_PYR-1 MEHAVEDLFRNSGGYATTAALLRVMSRQQLDVRVRKGELIRVWHGVYAAT
Mb2272|M.bovis_AF2122/97 ------------------------MTRQQLDVQVKNGGLVRVWYGVYAAQ
Rv2248|M.tuberculosis_H37Rv ------------------------MTRQQLDVQVKNGGLVRVWYGVYAAQ
MMAR_3341|M.marinum_M MPTDAQALLQKSGGFATTAQLLTVMTRQQLDVRVRNGSLVRVWHGVYAAE
MUL_1301|M.ulcerans_Agy99 ------------------------MTGQQLDVRVRNGSLVRVWHGVYAAE
MAB_3617|M.abscessus_ATCC_1997 MHPSIRALFHGRGAIR-AGELQEILSAKRISSLIRDGHLHRPWHGVYTLP
MSMEG_1733|M.smegmatis_MC2_155 MNPQLMRLFDDQRGVATSGQILGLITRYAFDQALKTGVLERIWPGIYCLG
TH_1835|M.thermoresistible__bu --------------------------------------------------
MAV_1002|M.avium_104 ----------------------------------------MVHRNVYVRR
Mflv_1335|M.gilvum_PYR-GCK QPDSRGRLNSLDAFLGQHAVACLGTAASLYGFDTEATETVHILDPG-ARV
Mvan_5457|M.vanbaalenii_PYR-1 EPDYLGRLQALDSYIGQPAVACMGTAAVLYGFDNEATSAVHILDPG-VRV
Mb2272|M.bovis_AF2122/97 EPDLLGRLAALDVFMGGHAVACLGTAAALYGFDTENTVAIHMLDPG-VRM
Rv2248|M.tuberculosis_H37Rv EPDLLGRLAALDVFMGGHAVACLGTAAALYGFDTENTVAIHMLDPG-VRM
MMAR_3341|M.marinum_M EPNLLGRLTALDVFMGRPVVACMGTAATLYGFDTECSSAVHVLDPG-VRM
MUL_1301|M.ulcerans_Agy99 EPNLLGRLTALDVFMGRPVVACMGTAATLYGFDTECSSAVHVLDPG-VRM
MAB_3617|M.abscessus_ATCC_1997 NPTVEIQLRALDLVADAHVPVCMGTAAASYGFDTERDGALHVINPVPGQL
MSMEG_1733|M.smegmatis_MC2_155 EPTEPLLLRGLDLSAGTRVAACLTTAAALHGFDTEGSTDLHVLNPPRHQL
TH_1835|M.thermoresistible__bu --------------------------------------------------
MAV_1002|M.avium_104 GQQLTPVTRAVAAWLWSGRTATLAGLSAAALHRTAWIDDWLPAELNRAGR
Mflv_1335|M.gilvum_PYR-GCK RPVDGLMVHQRVGAPLRRVDG----RLATAPAWTAVEVARVLPRPRALAT
Mvan_5457|M.vanbaalenii_PYR-1 RPTVGLMVHQRVGAPLGRVRG----RLATSPAWTAVEVARTLHRPRALAT
Mb2272|M.bovis_AF2122/97 RPTVGLMVHQRVGARLQRVSG----RLATAPAWTAVEVARQLRRPRALAT
Rv2248|M.tuberculosis_H37Rv RPTVGLMVHQRVGARLQRVSG----RLATAPAWTAVEVARQLRRPRALAT
MMAR_3341|M.marinum_M RPTVGLMVHQRIGARLQRVAG----RLATAPAWTAVEVARALRRPRALAT
MUL_1301|M.ulcerans_Agy99 RPTIGLMVHQRIGARLQRVAG----QLATAPPWTAAEVARALRRPRALAT
MAB_3617|M.abscessus_ATCC_1997 RPRPNLVVHQRLGAPLRYVDG----RLTTAPDWTAIEIARTLRPSRAIGT
MSMEG_1733|M.smegmatis_MC2_155 RSVDGLVVHRREGAPLTVIDVDGDVRYVTAPAWTAVEVARALRRPRALAT
TH_1835|M.thermoresistible__bu --------------------------------------------------
MAV_1002|M.avium_104 DKARGIILHSDTLCDDETTMRDG--MSLTTPARTAFDLGRRKGLTTAVIR
Mflv_1335|M.gilvum_PYR-GCK LDAALHSGLCTAVELGAAAHEQRGRRGIVKVRELLAIADGRAESPMESEA
Mvan_5457|M.vanbaalenii_PYR-1 LDAALRTGLCTPVELHAAVTEQRGRRGIVAVRELLPLADARAESPMESEA
Mb2272|M.bovis_AF2122/97 LEAALRSMRCARSEIENAVAEQRGRRGIVAARELLPFADGRAESAMESEA
Rv2248|M.tuberculosis_H37Rv LDAALRSMRCARSEIENAVAEQRGRRGIVAARELLPFADGRAESAMESEA
MMAR_3341|M.marinum_M LDAALRSMQCTRDQIESAVAEQHGRRGIVAVRELLPLADPRAESAMESET
MUL_1301|M.ulcerans_Agy99 LDAALRSMQCTRDQIESAVAEQHGRRGIVAVRELLPLADPRAESAMESET
MAB_3617|M.abscessus_ATCC_1997 LDAALRSGHCSPGGLRHAARMQAGRRGIVHVRGLLTHADGRSESPMESET
MSMEG_1733|M.smegmatis_MC2_155 LDAALRSGKCTRADVWRAALDQAGRRGIVAVRNLIALADPRAESPMESEA
TH_1835|M.thermoresistible__bu ---------------------------------LIAIADGRAESPMESEA
MAV_1002|M.avium_104 LDALMHASDVKTADVELLADRHRGARGLVQLRRVLTLVDGGAESPYETKT
::. .* :**. *:::
Mflv_1335|M.gilvum_PYR-GCK RLVMHDHDLPRPELQYVIDGTHDDM-WRVDFAWPEHHVAAEYDSMDWHSG
Mvan_5457|M.vanbaalenii_PYR-1 RLAMHDYGVPRPELQYVVHGAWDS--WRVDFAWPEVLVAAEYESVDWHTG
Mb2272|M.bovis_AF2122/97 RLVMIDHGLPLPELQYPIHGHGGEM-WRVDFAWPDMRLAAEYESIEWHAG
Rv2248|M.tuberculosis_H37Rv RLVMIDHGLPLPELQYPIHGHGGEM-WRVDFAWPDMRLAAEYESIEWHAG
MMAR_3341|M.marinum_M RLVMIDGGLARPELQYLIHGSDGEL-WRVDFAWPDLRLAAEYDSIDWHAG
MUL_1301|M.ulcerans_Agy99 RLVMIDGGLARPELQYLIHGSDGEL-WRVDFAWPDLRLAAEYDSIDWHAG
MAB_3617|M.abscessus_ATCC_1997 RLLFIDSGVPAPELQATICDRYGTV-WRVDFLWRSARLIGEYDSDEWHSG
MSMEG_1733|M.smegmatis_MC2_155 RLMMLDAGLPAPELQHEVIDGMGKL-RRLDFAWPECRVAVEYDGDDWHGN
TH_1835|M.thermoresistible__bu RLAMIDGGLPIPELQYELRDGAGRL-RRVDFAWPRHRVAVEYDGVDWHSG
MAV_1002|M.avium_104 RLLLAGSGLPRPQTQIEVRNEWGAVLARIDMGWEEWKVGVEFDGAQHWTD
** : . .:. *: * : . . *:*: * : *::. : .
Mflv_1335|M.gilvum_PYR-GCK RVAMLRDRARYAGIQHARWTVIPIVVTDVRVHPARLAARIADHLLRAAS-
Mvan_5457|M.vanbaalenii_PYR-1 RDAMLKDKARFAGLQHAAWTVIPITVTDVRISPERLAERIKEHLWRAAHT
Mb2272|M.bovis_AF2122/97 PAEMLRDKTRWAKLQELGWTIVPIVVDDVRREPGRLAARIARHLDRARMA
Rv2248|M.tuberculosis_H37Rv PAEMLRDKTRWAKLQELGWTIVPIVVDDVRREPGRLAARIARHLDRARMA
MMAR_3341|M.marinum_M RVEMLRDKTRWAKIQDLGWTIIPIVVDDVRREPGRLVQRIGNHLDRLRAA
MUL_1301|M.ulcerans_Agy99 RVEMLRDKTRWAKIQDLGWTIIPIVVDDVRREPGRLVQRIGNHLDRLRAA
MAB_3617|M.abscessus_ATCC_1997 PAAMRKDKLKTARLQECGWTVIPITVDDIRRHRDELVARINTHLRHHAA-
MSMEG_1733|M.smegmatis_MC2_155 PDALRNDRVRAAALSDVGWLVIAIVSEDVRLRPQETVGRIDRQLGLARAA
TH_1835|M.thermoresistible__bu PDAMRRDRDRTAALMDVGWTVIAIVLEDVRYRTREFVGRVDAQLRRAQAA
MAV_1002|M.avium_104 PAQRTRDIDRFAELEARGWTIVRVSADMLRYRPYDILSRTRNALRASGCP
.* : * : * :: : :* * *
Mflv_1335|M.gilvum_PYR-GCK -----------------------------------
Mvan_5457|M.vanbaalenii_PYR-1 ASSHKLAL---------------------------
Mb2272|M.bovis_AF2122/97 G----------------------------------
Rv2248|M.tuberculosis_H37Rv G----------------------------------
MMAR_3341|M.marinum_M S----------------------------------
MUL_1301|M.ulcerans_Agy99 S----------------------------------
MAB_3617|M.abscessus_ATCC_1997 -----------------------------------
MSMEG_1733|M.smegmatis_MC2_155 -----------------------------------
TH_1835|M.thermoresistible__bu -----------------------------------
MAV_1002|M.avium_104 LRSPSVDLLGTTQPISPNKSTFGGKGRPFGGKGRP