For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RKVLDEVLRRCNGYATTAALLDVMSRQQLDGLVRRRELVRVWHGVYAVAQPDSRGRLNSLDAFLGQHAVA CLGTAASLYGFDTEATETVHILDPGARVRPVDGLMVHQRVGAPLRRVDGRLATAPAWTAVEVARVLPRPR ALATLDAALHSGLCTAVELGAAAHEQRGRRGIVKVRELLAIADGRAESPMESEARLVMHDHDLPRPELQY VIDGTHDDMWRVDFAWPEHHVAAEYDSMDWHSGRVAMLRDRARYAGIQHARWTVIPIVVTDVRVHPARLA ARIADHLLRAAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1335 | - | - | 100% (293) | hypothetical protein Mflv_1335 |
| M. gilvum PYR-GCK | Mflv_4824 | - | 4e-76 | 53.41% (279) | hypothetical protein Mflv_4824 |
| M. gilvum PYR-GCK | Mflv_1289 | - | 3e-24 | 31.40% (258) | hypothetical protein Mflv_1289 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2272 | - | 2e-99 | 67.79% (267) | hypothetical protein Mb2272 |
| M. tuberculosis H37Rv | Rv2248 | - | 1e-100 | 68.16% (267) | hypothetical protein Rv2248 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3617 | - | 9e-72 | 49.11% (281) | hypothetical protein MAB_3617 |
| M. marinum M | MMAR_3341 | - | 1e-104 | 65.97% (288) | hypothetical protein MMAR_3341 |
| M. avium 104 | MAV_0642 | - | 2e-20 | 29.39% (262) | hypothetical protein MAV_0642 |
| M. smegmatis MC2 155 | MSMEG_1733 | - | 5e-70 | 51.99% (277) | hypothetical protein MSMEG_1733 |
| M. thermoresistible (build 8) | TH_1835 | - | 1e-29 | 57.52% (113) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1301 | - | 4e-97 | 65.31% (271) | hypothetical protein MUL_1301 |
| M. vanbaalenii PYR-1 | Mvan_5457 | - | 1e-119 | 73.26% (288) | hypothetical protein Mvan_5457 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1335|M.gilvum_PYR-GCK MRKVLDEVLRRCNGYATTAALLDVMSRQQLDGLVRRRELVRVWHGVYAVA
Mvan_5457|M.vanbaalenii_PYR-1 MEHAVEDLFRNSGGYATTAALLRVMSRQQLDVRVRKGELIRVWHGVYAAT
Mb2272|M.bovis_AF2122/97 ------------------------MTRQQLDVQVKNGGLVRVWYGVYAAQ
Rv2248|M.tuberculosis_H37Rv ------------------------MTRQQLDVQVKNGGLVRVWYGVYAAQ
MMAR_3341|M.marinum_M MPTDAQALLQKSGGFATTAQLLTVMTRQQLDVRVRNGSLVRVWHGVYAAE
MUL_1301|M.ulcerans_Agy99 ------------------------MTGQQLDVRVRNGSLVRVWHGVYAAE
MSMEG_1733|M.smegmatis_MC2_155 MNPQLMRLFDDQRGVATSGQILGLITRYAFDQALKTGVLERIWPGIYCLG
TH_1835|M.thermoresistible__bu --------------------------------------------------
MAB_3617|M.abscessus_ATCC_1997 MHPSIRALFHG-RGAIRAGELQEILSAKRISSLIRDGHLHRPWHGVYTLP
MAV_0642|M.avium_104 --------------MAEPFIGSEAVASGLVTPYALRSRFVRVHPDVYVPA
Mflv_1335|M.gilvum_PYR-GCK QPDSRGRLNSLDAFLGQHAVACLG--TAASLYGFDTEATETVHILDPG-A
Mvan_5457|M.vanbaalenii_PYR-1 EPDYLGRLQALDSYIGQPAVACMG--TAAVLYGFDNEATSAVHILDPG-V
Mb2272|M.bovis_AF2122/97 EPDLLGRLAALDVFMGGHAVACLG--TAAALYGFDTENTVAIHMLDPG-V
Rv2248|M.tuberculosis_H37Rv EPDLLGRLAALDVFMGGHAVACLG--TAAALYGFDTENTVAIHMLDPG-V
MMAR_3341|M.marinum_M EPNLLGRLTALDVFMGRPVVACMG--TAATLYGFDTECSSAVHVLDPG-V
MUL_1301|M.ulcerans_Agy99 EPNLLGRLTALDVFMGRPVVACMG--TAATLYGFDTECSSAVHVLDPG-V
MSMEG_1733|M.smegmatis_MC2_155 EPTEPLLLRGLDLSAGTRVAACLT--TAAALHGFDTEGSTDLHVLNPPRH
TH_1835|M.thermoresistible__bu --------------------------------------------------
MAB_3617|M.abscessus_ATCC_1997 NPTVEIQLRALDLVADAHVPVCMG--TAAASYGFDTERDGALHVINPVPG
MAV_0642|M.avium_104 GTALSAGLRARSAWLWSRRRGVVAGRSAAALYGTKWIDDRAPAQLLYPYR
Mflv_1335|M.gilvum_PYR-GCK RVRPVDGLMVHQRVGAPLRRVDG----RLATAPAWTAVEVARVLPRPRAL
Mvan_5457|M.vanbaalenii_PYR-1 RVRPTVGLMVHQRVGAPLGRVRG----RLATSPAWTAVEVARTLHRPRAL
Mb2272|M.bovis_AF2122/97 RMRPTVGLMVHQRVGARLQRVSG----RLATAPAWTAVEVARQLRRPRAL
Rv2248|M.tuberculosis_H37Rv RMRPTVGLMVHQRVGARLQRVSG----RLATAPAWTAVEVARQLRRPRAL
MMAR_3341|M.marinum_M RMRPTVGLMVHQRIGARLQRVAG----RLATAPAWTAVEVARALRRPRAL
MUL_1301|M.ulcerans_Agy99 RMRPTIGLMVHQRIGARLQRVAG----QLATAPPWTAAEVARALRRPRAL
MSMEG_1733|M.smegmatis_MC2_155 QLRSVDGLVVHRREGAPLTVIDVDGDVRYVTAPAWTAVEVARALRRPRAL
TH_1835|M.thermoresistible__bu --------------------------------------------------
MAB_3617|M.abscessus_ATCC_1997 QLRPRPNLVVHQRLGAPLRYVDG----RLTTAPDWTAIEIARTLRPSRAI
MAV_0642|M.avium_104 RPPDGIQTWSDRLVGDEIQTIGG----MPVTTPARTALDIACRSPVDKAV
Mflv_1335|M.gilvum_PYR-GCK ATLDAALHSGLCTAVELGAAAHEQRGRRGIVKVRELLAIADGRAESPMES
Mvan_5457|M.vanbaalenii_PYR-1 ATLDAALRTGLCTPVELHAAVTEQRGRRGIVAVRELLPLADARAESPMES
Mb2272|M.bovis_AF2122/97 ATLEAALRSMRCARSEIENAVAEQRGRRGIVAARELLPFADGRAESAMES
Rv2248|M.tuberculosis_H37Rv ATLDAALRSMRCARSEIENAVAEQRGRRGIVAARELLPFADGRAESAMES
MMAR_3341|M.marinum_M ATLDAALRSMQCTRDQIESAVAEQHGRRGIVAVRELLPLADPRAESAMES
MUL_1301|M.ulcerans_Agy99 ATLDAALRSMQCTRDQIESAVAEQHGRRGIVAVRELLPLADPRAESAMES
MSMEG_1733|M.smegmatis_MC2_155 ATLDAALRSGKCTRADVWRAALDQAGRRGIVAVRNLIALADPRAESPMES
TH_1835|M.thermoresistible__bu -----------------------------------LIAIADGRAESPMES
MAB_3617|M.abscessus_ATCC_1997 GTLDAALRSGHCSPGGLRHAARMQAGRRGIVHVRGLLTHADGRSESPMES
MAV_0642|M.avium_104 AAIDALARATELKVLEIELLADRYRGRRGITRARNVLPLVDAGAESPRET
::. .* :**. *:
Mflv_1335|M.gilvum_PYR-GCK EARLVMHDHDLPRPELQYVIDGTHDDMWRVDFAWPEHHVAAEYDSMDWHS
Mvan_5457|M.vanbaalenii_PYR-1 EARLAMHDYGVPRPELQYVVHGAWDS-WRVDFAWPEVLVAAEYESVDWHT
Mb2272|M.bovis_AF2122/97 EARLVMIDHGLPLPELQYPIHGHGGEMWRVDFAWPDMRLAAEYESIEWHA
Rv2248|M.tuberculosis_H37Rv EARLVMIDHGLPLPELQYPIHGHGGEMWRVDFAWPDMRLAAEYESIEWHA
MMAR_3341|M.marinum_M ETRLVMIDGGLARPELQYLIHGSDGELWRVDFAWPDLRLAAEYDSIDWHA
MUL_1301|M.ulcerans_Agy99 ETRLVMIDGGLARPELQYLIHGSDGELWRVDFAWPDLRLAAEYDSIDWHA
MSMEG_1733|M.smegmatis_MC2_155 EARLMMLDAGLPAPELQHEVIDGMGKLRRLDFAWPECRVAVEYDGDDWHG
TH_1835|M.thermoresistible__bu EARLAMIDGGLPIPELQYELRDGAGRLRRVDFAWPRHRVAVEYDGVDWHS
MAB_3617|M.abscessus_ATCC_1997 ETRLLFIDSGVPAPELQATICDRYGTVWRVDFLWRSARLIGEYDSDEWHS
MAV_0642|M.avium_104 WLRLLLLRAGFPRPRTQLPVRQYGALIACLDMGWEDIKLAVEYDGDQHRT
** : ... *. * : :*: * : **:. : :
Mflv_1335|M.gilvum_PYR-GCK GRVAMLRDRARYAGIQHARWTVIPIVVTDVRVHPARLAARIADHLLRAAS
Mvan_5457|M.vanbaalenii_PYR-1 GRDAMLKDKARFAGLQHAAWTVIPITVTDVRISPERLAERIKEHLWRAAH
Mb2272|M.bovis_AF2122/97 GPAEMLRDKTRWAKLQELGWTIVPIVVDDVRREPGRLAARIARHLDRARM
Rv2248|M.tuberculosis_H37Rv GPAEMLRDKTRWAKLQELGWTIVPIVVDDVRREPGRLAARIARHLDRARM
MMAR_3341|M.marinum_M GRVEMLRDKTRWAKIQDLGWTIIPIVVDDVRREPGRLVQRIGNHLDRLRA
MUL_1301|M.ulcerans_Agy99 GRVEMLRDKTRWAKIQDLGWTIIPIVVDDVRREPGRLVQRIGNHLDRLRA
MSMEG_1733|M.smegmatis_MC2_155 NPDALRNDRVRAAALSDVGWLVIAIVSEDVRLRPQETVGRIDRQLGLARA
TH_1835|M.thermoresistible__bu GPDAMRRDRDRTAALMDVGWTVIAIVLEDVRYRTREFVGRVDAQLRRAQA
MAB_3617|M.abscessus_ATCC_1997 GPAAMRKDKLKTARLQECGWTVIPITVDDIRRHRDELVARINTHLRHHAA
MAV_0642|M.avium_104 DRRQFTKDIRRAEVLAELGWTVVRVTAEDT---PAGIIARVPTAWTRRAC
. : .* : : . * :: :. * *:
Mflv_1335|M.gilvum_PYR-GCK -----------
Mvan_5457|M.vanbaalenii_PYR-1 TASSHKLAL--
Mb2272|M.bovis_AF2122/97 AG---------
Rv2248|M.tuberculosis_H37Rv AG---------
MMAR_3341|M.marinum_M AS---------
MUL_1301|M.ulcerans_Agy99 AS---------
MSMEG_1733|M.smegmatis_MC2_155 A----------
TH_1835|M.thermoresistible__bu A----------
MAB_3617|M.abscessus_ATCC_1997 -----------
MAV_0642|M.avium_104 TGSEKPARNSR