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GTEALSAGALTERDLRRSCTRIYRNVYQRGADFTASDRAIAAWLWSGRRAVVAGNSAAALLGAQWVDPRA PAELITDRKRPPPLIVARNETLLPDEITEVRGVPVTTPARTAYDLGRRPGLVAAVIAIDSLARATGLTTE CVEPLMRAHRGARGVRQLRRVLPLIDAGAESPQETRTRLAIVGAGLPKPSTQITVHNDWGFVLARIDLGW EQWRVGVEYDGAQHWTDPRIRAKDIDRVAELERRGWRIIRVSADLLRNRPDVLVGRIREALCAAGCPL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3234 | - | - | 100% (279) | hypothetical protein MAV_3234 |
| M. avium 104 | MAV_1002 | - | 1e-82 | 58.91% (258) | hypothetical protein MAV_1002 |
| M. avium 104 | MAV_0642 | - | 4e-62 | 46.04% (278) | hypothetical protein MAV_0642 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3585c | - | 2e-80 | 56.12% (278) | hypothetical protein Mb3585c |
| M. gilvum PYR-GCK | Mflv_1289 | - | 3e-58 | 44.64% (280) | hypothetical protein Mflv_1289 |
| M. tuberculosis H37Rv | Rv3555c | - | 2e-79 | 55.76% (278) | hypothetical protein Rv3555c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1200 | - | 9e-71 | 48.38% (277) | hypothetical protein MAB_1200 |
| M. marinum M | MMAR_4658 | - | 8e-73 | 52.57% (272) | hypothetical protein MMAR_4658 |
| M. smegmatis MC2 155 | MSMEG_5314 | - | 1e-74 | 53.45% (275) | hypothetical protein MSMEG_5314 |
| M. thermoresistible (build 8) | TH_3487 | - | 1e-80 | 53.41% (279) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0276 | - | 3e-69 | 51.47% (272) | hypothetical protein MUL_0276 |
| M. vanbaalenii PYR-1 | Mvan_5044 | - | 7e-82 | 54.64% (280) | hypothetical protein Mvan_5044 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3585c|M.bovis_AF2122/97 -------MDELPWPVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPAGVEL
Rv3555c|M.tuberculosis_H37Rv -------MDELPWPVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPAGVEL
MAB_1200|M.abscessus_ATCC_1997 -------MGDIPWPFRSTEMLSTGAVTEHYIRTRYRQLYPGICVPREVEV
MSMEG_5314|M.smegmatis_MC2_155 MGCDRPGMQTIDWPFRAVEALEAGALTFRELRRFHTAVYPGVWVPREAEL
MMAR_4658|M.marinum_M -------MEILDWPFRGTEALAAGAVTPHRLRTHFEMVHRNVYIPRGKKL
MUL_0276|M.ulcerans_Agy99 -------MEILDWPFRGTEALAAGAVTPHRLRTHFEMVHRNVYIARGKKL
TH_3487|M.thermoresistible__bu ---------MAEGPFLGSEARAAGLVTRRTLRSRHRLIYQNVYLPVGVQL
Mvan_5044|M.vanbaalenii_PYR-1 -----------MDPFLGTEALAAGSLTRYRLKTRFELVHRNVYALNREQL
MAV_3234|M.avium_104 ---------------MGTEALSAGALTERDLRRSCTRIYRNVYQ-RGADF
Mflv_1289|M.gilvum_PYR-GCK -------MTAMDRVILGGEAVRAGVATRHELARDYTRLYRGVFVRNGIEI
. * : . : :: .: ..
Mb3585c|M.bovis_AF2122/97 TARQRAHAAWLWSRRRAVVAGNSAAALLGAKWVNPALDAELVHANRKPPP
Rv3555c|M.tuberculosis_H37Rv TARQRAHAAWLWSRRRAVVAGNSAAALLGAKWVNPALDAELVHANRKPPP
MAB_1200|M.abscessus_ATCC_1997 SATQRAYSAWLWTGRRGVIAGLAASAVHGAKWVEAGVVVDLIHRHHKTAR
MSMEG_5314|M.smegmatis_MC2_155 SPVQRARAAWLWSGRAGVPAGLSASAMLGSKWIDQRDPAELIHTNRRPPR
MMAR_4658|M.marinum_M TAVTRAIAAWLWSGRSATAVGLSAAALHRTGWIDDWLPAELNRRGRDKAR
MUL_0276|M.ulcerans_Agy99 TAVTRAIAAWLWSGRSATAVGLSPAPLHRTGWIDDWLPAELNRRGRDKAR
TH_3487|M.thermoresistible__bu TAQTRAVAAWLWARRDATVAGLSAAALHGTKWIDPALPAELIRPSPGSPD
Mvan_5044|M.vanbaalenii_PYR-1 TPVQKARAAWLWSGRRGTLVGLSAAAVLGSRWIDARLPAELNQRSQHKTP
MAV_3234|M.avium_104 TASDRAIAAWLWSGRRAVVAGNSAAALLGAQWVDPRAPAELITDRKRPPP
Mflv_1289|M.gilvum_PYR-GCK TLRDRAIGAWLATGRKGVISGRTAAALHGAPLVDLTIPIELTGAKGRSQE
: :* .*** : * .. * :.:.: : :: :*
Mb3585c|M.bovis_AF2122/97 RIVVHTDRLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRLDALA
Rv3555c|M.tuberculosis_H37Rv RIVVHTDRLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRLDALA
MAB_1200|M.abscessus_ATCC_1997 GLRIHRDTLMDNEIDRIEGIAVTSPARTAFDVGRWLP-QAGAVERIDALM
MSMEG_5314|M.smegmatis_MC2_155 LLTVHSDTLSDGETQVIDGMVVTTPARTAFDLGRRLP-FVDGVQRIDALM
MMAR_4658|M.marinum_M GIISHSACLDEDEVCVRDGIALTTPARTAFDLGRRKG-LTTAVIRLDALT
MUL_0276|M.ulcerans_Agy99 DIISHSACLDEDEVCVRDGIALTTPARTAFDLGRRKG-LTTAVIRLDALT
TH_3487|M.thermoresistible__bu GIVIHRDRLEPGEVCTLRGIPVTTPARTAYDIGRRQT-LTRAVVRLDALA
Mvan_5044|M.vanbaalenii_PYR-1 GIVLRADTLGPDEIVTARGMPVTSPARTAFDLGRRRG-LTLAVIRMDALM
MAV_3234|M.avium_104 LIVARNETLLPDEITEVRGVPVTTPARTAYDLGRRPG-LVAAVIAIDSLA
Mflv_1289|M.gilvum_PYR-GCK GLILRNESLAPDEVTRRSGLPVSTRVRTAFDLGRHLE-RPEALARLDALM
: : * * *: ::: .***:*:** .: :*:*
Mb3585c|M.bovis_AF2122/97 NSTDVKVADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTRLVLI
Rv3555c|M.tuberculosis_H37Rv NSTDVKVADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTRLVLI
MAB_1200|M.abscessus_ATCC_1997 AATGLVTEQVEDVMKKHKGVRGLARLRSVLALVDGGSESPQETRTRLLLV
MSMEG_5314|M.smegmatis_MC2_155 NATHVKVEEVLALAEGYRGARGVRRLRLILEYVDGGAESPYESSTRIMLV
MMAR_4658|M.marinum_M RATELKVADVEMLAERHRGARGLIQLRQALPLVDAGADSPYETRIRLLVI
MUL_0276|M.ulcerans_Agy99 RATELKVADVEMLAERHRGARGLIQLRQALPLVDAGADSPYETRIRLLII
TH_3487|M.thermoresistible__bu NATGLTADAVTAVIDRRRGARGLVRLRRAVGLMDGGAASPPETRTRLLLL
Mvan_5044|M.vanbaalenii_PYR-1 RTTGATTSDIATLLTRHKGARGLVQLRRALELVDPASESPQESRTRLLLV
MAV_3234|M.avium_104 RATGLTTECVEPLMRAHRGARGVRQLRRVLPLIDAGAESPQETRTRLAIV
Mflv_1289|M.gilvum_PYR-GCK WNQRYAIDDVLALAERHPRARGVTQLRELLPLVDGGAASPRESALRLALI
: : .**: :** : :* .: ** *: *: ::
Mb3585c|M.bovis_AF2122/97 DAGLPKPQTQIRVFDDYGDFVARIDLGYEQLRVGVEYDGPQHWTDPAQRA
Rv3555c|M.tuberculosis_H37Rv DAGLPKPQTQIRVFDDYGDFVARIDLGYEQLRVGVEYDGPQHWTDPAQRA
MAB_1200|M.abscessus_ATCC_1997 KSGFPPPQTQIRVFNRYGDFIARIDMGWEDLKVGVEFDGAQHWLDARQRS
MSMEG_5314|M.smegmatis_MC2_155 TNGFPEPETQIEVADASGTVFARLDMGWPEYRVAVEFDGAQHWTDSEQRS
MMAR_4658|M.marinum_M RSGLPAPQTEIKVLDDWGAVAARIGMGWPECKVGVEFDSAGQWNN-AARS
MUL_0276|M.ulcerans_Agy99 RSGLPAPQTEIKVLDDRGAVAARIGMGWPECKVGVEFDSAGQWNN-AARS
TH_3487|M.thermoresistible__bu AAGFPRPRTQVVVCDPFGYFIGRIDIGWPEYRVGVEYDGAWHWADAAAHA
Mvan_5044|M.vanbaalenii_PYR-1 KAGLPPERSQIDVFDRDGYHVGRVDMGWETWKVGVEYEGEQHWTNPEQYA
MAV_3234|M.avium_104 GAGLPKPSTQITVHNDWGFVLARIDLGWEQWRVGVEYDGAQHWTDPRIRA
Mflv_1289|M.gilvum_PYR-GCK DSGFPKPETQIPVFAG-TRPIAFLDMGWEEYGVAVEYDGDHHRKDRRQYV
*:* ::: * . :.:*: *.**::. : :
Mb3585c|M.bovis_AF2122/97 RDIERSTALLDLGWTIIRVTSELLRYRRGTFVGRVD----------AAMR
Rv3555c|M.tuberculosis_H37Rv RDIERSTALLDLGWTIIRVTSELLWYRRGTFVGRVD----------AAMR
MAB_1200|M.abscessus_ATCC_1997 HDIDRASELAAQGWAIVRVSAEMLRHRAGTVVARVD----------AALR
MSMEG_5314|M.smegmatis_MC2_155 WDIDRQAMLEALGWTVIRVSAGLLHGRRQVVVDRVR----------AALL
MMAR_4658|M.marinum_M DAVDRSAELEARGWTIVRVNAQTLKNRPDIVVAQVR----------HALV
MUL_0276|M.ulcerans_Agy99 DAFDRSAELEARGWTIVRVNTQTLKNRPDIVVTQVR----------HALV
TH_3487|M.thermoresistible__bu QTIDRVADLEEQGWIIIRISRDILRYRPGVFLARVRNALRAHGWPDHASV
Mvan_5044|M.vanbaalenii_PYR-1 HDIDRQAALEAEGWRIIRVSAEILRDRPTTIVSRVWLALR----AAGAPV
MAV_3234|M.avium_104 KDIDRVAELERRGWRIIRVSADLLRNRPDVLVGRIR----------EALC
Mflv_1289|M.gilvum_PYR-GCK KDIARLRMLEERGWSVVRVIAEDM---PAAWLRRVA----------DALR
. * * ** ::*: : : :: *
Mb3585c|M.bovis_AF2122/97 AAGWRP--------------
Rv3555c|M.tuberculosis_H37Rv AAGWRP--------------
MAB_1200|M.abscessus_ATCC_1997 NAARPTTSASLTRISGQISA
MSMEG_5314|M.smegmatis_MC2_155 ARGCRMGPGRAERAF-----
MMAR_4658|M.marinum_M RRT-----------------
MUL_0276|M.ulcerans_Agy99 RRT-----------------
TH_3487|M.thermoresistible__bu RLDARLEP------------
Mvan_5044|M.vanbaalenii_PYR-1 QPPNLNL-------------
MAV_3234|M.avium_104 AAGCPL--------------
Mflv_1289|M.gilvum_PYR-GCK RKGCPLAWVAGKTIAA----