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MTDLDAVFRAQGGVATSGQLLRFYSRSRLDIEIRDGWLIKVWPGVYSRDEPDTMTRLRGLDLRAGEPVAI CLGTAAAAYGFDTEDTHDIHALNPPRHQLRNSDGLIVHRRDGAPLGVADGRPATTAAWTAVEVARSLRRP RALATLDAALRSTSCTRQQLTVAAAEQAGRRGIVAVRELIPLADALAESPMESEARLAMLDGGLPPPVLQ HEIVDLSGRTWRVDFAWLDAKVAVEYDGFDWHSDQEHFARDRQKRAALNEVNWRMLSVVSDDVRKQSHDM VRRIEHELTRRIAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3817 | - | - | 100% (294) | hypothetical protein Mvan_3817 |
| M. vanbaalenii PYR-1 | Mvan_5457 | - | 1e-77 | 52.26% (287) | hypothetical protein Mvan_5457 |
| M. vanbaalenii PYR-1 | Mvan_5044 | - | 4e-24 | 27.68% (271) | hypothetical protein Mvan_5044 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2272 | - | 3e-74 | 52.63% (266) | hypothetical protein Mb2272 |
| M. gilvum PYR-GCK | Mflv_4824 | - | 8e-87 | 57.53% (292) | hypothetical protein Mflv_4824 |
| M. tuberculosis H37Rv | Rv2248 | - | 1e-74 | 53.01% (266) | hypothetical protein Rv2248 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3617 | - | 1e-67 | 46.53% (288) | hypothetical protein MAB_3617 |
| M. marinum M | MMAR_1222 | - | 1e-93 | 58.56% (292) | hypothetical protein MMAR_1222 |
| M. avium 104 | MAV_3351 | - | 5e-25 | 32.37% (278) | hypothetical protein MAV_3351 |
| M. smegmatis MC2 155 | MSMEG_1733 | - | 1e-89 | 58.74% (286) | hypothetical protein MSMEG_1733 |
| M. thermoresistible (build 8) | TH_1835 | - | 3e-31 | 55.17% (116) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2670 | - | 3e-89 | 58.01% (281) | hypothetical protein MUL_2670 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1733|M.smegmatis_MC2_155 MNPQLMRLFDDQRGVATSGQILGLITRYAFDQALKTGVLERIWPGIYCLG
TH_1835|M.thermoresistible__bu --------------------------------------------------
Mflv_4824|M.gilvum_PYR-GCK MDDELLALFDAQRGVALSGQILSLVPRRRFEQWLNTVVLERIWQGVYCLG
MMAR_1222|M.marinum_M MHAELARLLDAQGGVATSAQVLTFLTRRGLEADLKSGVLSRVWHGIYGRG
MUL_2670|M.ulcerans_Agy99 --------------MATSAQVLTVLTRRGLEADLKNGVLSRVWHGIYGRG
Mvan_3817|M.vanbaalenii_PYR-1 -MTDLDAVFRAQGGVATSGQLLRFYSRSRLDIEIRDGWLIKVWPGVYSRD
Mb2272|M.bovis_AF2122/97 ------------------------MTRQQLDVQVKNGGLVRVWYGVYAAQ
Rv2248|M.tuberculosis_H37Rv ------------------------MTRQQLDVQVKNGGLVRVWYGVYAAQ
MAB_3617|M.abscessus_ATCC_1997 MHPSIRALFHG-RGAIRAGELQEILSAKRISSLIRDGHLHRPWHGVYTLP
MAV_3351|M.avium_104 --------------MVEPFIGSEAVADGEVVKSALRTRYKRLFRDVYIHP
MSMEG_1733|M.smegmatis_MC2_155 --EPTEPLLLRGLDLSAGTRVAACLTTAAALHGFDTEGSTDLHVLNPPRH
TH_1835|M.thermoresistible__bu --------------------------------------------------
Mflv_4824|M.gilvum_PYR-GCK --EADDALRLAGLDLSSGRRVAVCLGTAAAIFGFDTEQPRDLHVLNPPGC
MMAR_1222|M.marinum_M --ELTSGLRLRGVDLAVGTPVAACLGTAAAAYGFDTEQTGDLHVLNPEGR
MUL_2670|M.ulcerans_Agy99 --ELTSGLRLRGVDLAVGTPVAACLGTAAAAYGFDTEQTGDLHVLNPEGR
Mvan_3817|M.vanbaalenii_PYR-1 --EPDTMTRLRGLDLRAGEPVAICLGTAAAAYGFDTEDTHDIHALNPPRH
Mb2272|M.bovis_AF2122/97 --EPDLLGRLAALDVFMGGHAVACLGTAAALYGFDTENTVAIHMLDPG-V
Rv2248|M.tuberculosis_H37Rv --EPDLLGRLAALDVFMGGHAVACLGTAAALYGFDTENTVAIHMLDPG-V
MAB_3617|M.abscessus_ATCC_1997 --NPTVEIQLRALDLVADAHVPVCMGTAAASYGFDTERDGALHVINPVPG
MAV_3351|M.avium_104 GAELSALTRARAGWLWSRRRGVIAGLSAAAVHGARWVDATAPLEILHSNR
MSMEG_1733|M.smegmatis_MC2_155 QLRSVDGLVVHRREGAPLTVIDVDGDVRYVTAPAWTAVEVARALRRPRAL
TH_1835|M.thermoresistible__bu --------------------------------------------------
Mflv_4824|M.gilvum_PYR-GCK ALRDADGLVVHRRDGAPLVTVEG----RRATSPAWTAIEVARSLRRPRAL
MMAR_1222|M.marinum_M QLRSTDGLTVHRRAGAPLTRLAG----RELTTPAWTAIEVARGLRRPRAL
MUL_2670|M.ulcerans_Agy99 QLRSTDGLTVHRRAGAPLTRLAG----RELRTPAWTAIEVARGLRRPRAL
Mvan_3817|M.vanbaalenii_PYR-1 QLRNSDGLIVHRRDGAPLGVADG----RPATTAAWTAVEVARSLRRPRAL
Mb2272|M.bovis_AF2122/97 RMRPTVGLMVHQRVGARLQRVSG----RLATAPAWTAVEVARQLRRPRAL
Rv2248|M.tuberculosis_H37Rv RMRPTVGLMVHQRVGARLQRVSG----RLATAPAWTAVEVARQLRRPRAL
MAB_3617|M.abscessus_ATCC_1997 QLRPRPNLVVHQRLGAPLRYVDG----RLTTAPDWTAIEIARTLRPSRAI
MAV_3351|M.avium_104 NPLPGLRIHSDRLESDEYALVDG----VPVTTPARTAVDLGCWHPVNDAV
MSMEG_1733|M.smegmatis_MC2_155 ATLDAALRSGKCTRADVWRAALDQAGRRGIVAVRNLIALADPRAESPMES
TH_1835|M.thermoresistible__bu -----------------------------------LIAIADGRAESPMES
Mflv_4824|M.gilvum_PYR-GCK ATLDAALRSGTCTRPDLWRAATEQKGRRGIVAVRNLLPLADARAESPGES
MMAR_1222|M.marinum_M ATLDAALRSGTCDRDDLDRAVCLQSGRRGVVAVRELLALASPLAESPMES
MUL_2670|M.ulcerans_Agy99 ATLDAALRSGTCDRDDLDRAVCLQSGRRGVVAVRELLALASPLAESPMES
Mvan_3817|M.vanbaalenii_PYR-1 ATLDAALRSTSCTRQQLTVAAAEQAGRRGIVAVRELIPLADALAESPMES
Mb2272|M.bovis_AF2122/97 ATLEAALRSMRCARSEIENAVAEQRGRRGIVAARELLPFADGRAESAMES
Rv2248|M.tuberculosis_H37Rv ATLDAALRSMRCARSEIENAVAEQRGRRGIVAARELLPFADGRAESAMES
MAB_3617|M.abscessus_ATCC_1997 GTLDAALRSGHCSPGGLRHAARMQAGRRGIVHVRGLLTHADGRSESPMES
MAV_3351|M.avium_104 AVIDDLLRATDCKVAECQLLADRYPGRRGMQSARAAIGLADAGAQSPKET
: *. ::*. *:
MSMEG_1733|M.smegmatis_MC2_155 EARLMMLDAGLPAPELQHEVIDGMG-KLRRLDFAWPECRVAVEYDGDDWH
TH_1835|M.thermoresistible__bu EARLAMIDGGLPIPELQYELRDGAG-RLRRVDFAWPRHRVAVEYDGVDWH
Mflv_4824|M.gilvum_PYR-GCK AARLAMLDADLPVPHLQYEFVDGNG-DLRRLDFAWPEAGVAAEYDGVDWH
MMAR_1222|M.marinum_M ETRLVMIEGGLPAPVLQYELVGSDG-RRWRLDFAWPGLRVAAEYDGVDWH
MUL_2670|M.ulcerans_Agy99 ETRLVMIEGGLPAPVLQYELVGSDG-RRWRLDFAWPGLRVAAEYDGVDWH
Mvan_3817|M.vanbaalenii_PYR-1 EARLAMLDGGLPPPVLQHEIVDLSG-RTWRVDFAWLDAKVAVEYDGFDWH
Mb2272|M.bovis_AF2122/97 EARLVMIDHGLPLPELQYPIHGHGG-EMWRVDFAWPDMRLAAEYESIEWH
Rv2248|M.tuberculosis_H37Rv EARLVMIDHGLPLPELQYPIHGHGG-EMWRVDFAWPDMRLAAEYESIEWH
MAB_3617|M.abscessus_ATCC_1997 ETRLLFIDSGVPAPELQATICDRYG-TVWRVDFLWRSARLIGEYDSDEWH
MAV_3351|M.avium_104 WLRLLLIRAGLPRPQTQIPVSDEFGGVTYYLDMGWEDFMVAAEYDGEQHR
** :: .:* * * . . * :*: * : **:. : :
MSMEG_1733|M.smegmatis_MC2_155 GNPDALRNDRVRAAALSDVGWLVIAIVSEDVRLRPQETVGRIDRQLGLAR
TH_1835|M.thermoresistible__bu SGPDAMRRDRDRTAALMDVGWTVIAIVLEDVRYRTREFVGRVDAQLRRAQ
Mflv_4824|M.gilvum_PYR-GCK SGPDAMQRDRRRYSALLAVGMVVIPIVAEDLRDGGWEMASRIRDQLRRAR
MMAR_1222|M.marinum_M SGPQAFLRDRRRSAALQELGWVIVPIVAGDVRHRPADLVQRLAGALARAQ
MUL_2670|M.ulcerans_Agy99 SGPQAFLRDRRRSAALQELGWVIVPIVAGDVRHRPAELVQRLAGALARAQ
Mvan_3817|M.vanbaalenii_PYR-1 SDQEHFARDRQKRAALNEVNWRMLSVVSDDVRKQSHDMVRRIEHELTRRI
Mb2272|M.bovis_AF2122/97 AGPAEMLRDKTRWAKLQELGWTIVPIVVDDVRREPGRLAARIARHLDRAR
Rv2248|M.tuberculosis_H37Rv AGPAEMLRDKTRWAKLQELGWTIVPIVVDDVRREPGRLAARIARHLDRAR
MAB_3617|M.abscessus_ATCC_1997 SGPAAMRKDKLKTARLQECGWTVIPITVDDIRRHRDELVARINTHLRHHA
MAV_3351|M.avium_104 RDRWQYTWDIRRRETLERLGWIVIQVVAGDR---PADIVSRVSAALARRG
. * : * . :: :. * . *: *
MSMEG_1733|M.smegmatis_MC2_155 AA--
TH_1835|M.thermoresistible__bu AA--
Mflv_4824|M.gilvum_PYR-GCK AA--
MMAR_1222|M.marinum_M AA--
MUL_2670|M.ulcerans_Agy99 AA--
Mvan_3817|M.vanbaalenii_PYR-1 AA--
Mb2272|M.bovis_AF2122/97 MAG-
Rv2248|M.tuberculosis_H37Rv MAG-
MAB_3617|M.abscessus_ATCC_1997 A---
MAV_3351|M.avium_104 VTLA