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PGMGEVILGGEAVRAGVVTRHELARWYTPLYRGVFVRKGVEVTLRDRAVGAWLATGRKGVIAGLAAAALH GAAWIDADIPIEVAGVKRRSHAGLITRSEVIATDEIVRRAGLPVTSRTRTAFDLGRQLDRAEALARLDAL MWNQPFSIDEVAELADRRPRVPGVGQLRDLLPLIDGGAASPRQSRLRLWLLDCGFPRPQTQIPVLEGSRP VAFLDMGWPEYQVAVEYDGDHHRKNRDQYVKDIARLRMLEALGWIVIRVIAEDRPAHWLERTEAALQSRG CRLAATELQLFVRTLAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5526 | - | - | 100% (298) | hypothetical protein Mvan_5526 |
| M. vanbaalenii PYR-1 | Mvan_1630 | - | 3e-75 | 53.02% (281) | hypothetical protein Mvan_1630 |
| M. vanbaalenii PYR-1 | Mvan_1730 | - | 1e-59 | 44.41% (286) | hypothetical protein Mvan_1730 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3741c | - | 5e-88 | 58.30% (283) | hypothetical protein Mb3741c |
| M. gilvum PYR-GCK | Mflv_1289 | - | 1e-116 | 71.58% (285) | hypothetical protein Mflv_1289 |
| M. tuberculosis H37Rv | Rv3714c | - | 5e-88 | 58.30% (283) | hypothetical protein Rv3714c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2184 | - | 1e-104 | 62.37% (295) | hypothetical protein MAB_2184 |
| M. marinum M | MMAR_0375 | - | 2e-69 | 51.08% (278) | hypothetical protein MMAR_0375 |
| M. avium 104 | MAV_4752 | - | 2e-69 | 50.00% (280) | hypothetical protein MAV_4752 |
| M. smegmatis MC2 155 | MSMEG_0850 | - | 3e-77 | 54.38% (274) | hypothetical protein MSMEG_0850 |
| M. thermoresistible (build 8) | TH_4125 | - | 2e-56 | 44.84% (281) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4737 | - | 3e-68 | 50.36% (278) | hypothetical protein MUL_4737 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3741c|M.bovis_AF2122/97 MLISRMSVRSASMSVMGDVFIGSEAITAGRLTRHELQRWYQPMFRGVYVS
Rv3714c|M.tuberculosis_H37Rv MLISRMSVRSASMSVMGDVFIGSEAITAGRLTRHELQRWYQPMFRGVYVS
MMAR_0375|M.marinum_M -----MDAREARAARSEDVFVGSEAVRRGRLSPYRLRTEFRAIYPDVYLP
MUL_4737|M.ulcerans_Agy99 -----MDAREARAARSEDVFVGSGAVRRGRLSPYRLRTEFRAIYPDVYLP
Mvan_5526|M.vanbaalenii_PYR-1 ------------MPGMGEVILGGEAVRAGVVTRHELARWYTPLYRGVFVR
Mflv_1289|M.gilvum_PYR-GCK ------------MTAMDRVILGGEAVRAGVATRHELARDYTRLYRGVFVR
MAB_2184|M.abscessus_ATCC_1997 ---------------MAAVFVGSEAVSAGQLTRHELQRFYRPIFRGVYLP
MSMEG_0850|M.smegmatis_MC2_155 ---------------MGEVVIGGEALAKGLVTRNDLRHHYRRLFPGVYVR
MAV_4752|M.avium_104 --------------MGEAPVVGSEELASGRLNRHRLRVAYRPVFPNVYLP
TH_4125|M.thermoresistible__bu ---------------MREVFIGSAALRGGGLTRGRLRWNYRAMYPDVYVA
.:*. : * . * : :: .*::
Mb3741c|M.bovis_AF2122/97 RRSVPTLWDRTVGAWLATRRHGVIAGNAASALHGAQWVDVDVAIELISPT
Rv3714c|M.tuberculosis_H37Rv RRSVPTLWDRTVGAWLATRRHGVIAGNAASALHGAQWVDVDVAIELISPT
MMAR_0375|M.marinum_M AHAAPSFRTRCKAAWLWTGRRGVLAGLAAAGLHGSDWIGDDEPVELIWRN
MUL_4737|M.ulcerans_Agy99 AHAAPSFRTRCKAAWLWTGRRGVLGGLAAAGLHGSDWIGDDEPVELIWRN
Mvan_5526|M.vanbaalenii_PYR-1 KGVEVTLRDRAVGAWLATGRKGVIAGLAAAALHGAAWIDADIPIEVAGVK
Mflv_1289|M.gilvum_PYR-GCK NGIEITLRDRAIGAWLATGRKGVISGRTAAALHGAPLVDLTIPIELTGAK
MAB_2184|M.abscessus_ATCC_1997 KSAEPTLRDRTVAAWLASGRRGVVAGLAASNLHGASWVDHDVPIELVGVK
MSMEG_0850|M.smegmatis_MC2_155 G--EPTLRDRTVGAWLWSGRRGVLAGVAASALHGSAWVDPDVPIELIWRN
MAV_4752|M.avium_104 AQVEPTLPLRIRAAWLWSGRTAVIAGAAAAAVHGAAWIPDAVPIELIHHN
TH_4125|M.thermoresistible__bu KDRPPTLRQFIVGAWLWSGREGVITGRAAAALHGAKYVDDATPIELIWKA
:: .*** : * .*: * :*: :**: : .:*:
Mb3741c|M.bovis_AF2122/97 TRPQHGLVIRRETLCDDEITRVVGLPVTTLARTAYDLGRHLSRGEAVARL
Rv3714c|M.tuberculosis_H37Rv TRPQHGLVIRRETLCDDEITRVVGLPVTTLARTAYDLGRHLSRGEAVARL
MMAR_0375|M.marinum_M PHPPAGVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVARL
MUL_4737|M.ulcerans_Agy99 PHPPAGVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVARL
Mvan_5526|M.vanbaalenii_PYR-1 RRSHAGLITRSEVIATDEIVRRAGLPVTSRTRTAFDLGRQLDRAEALARL
Mflv_1289|M.gilvum_PYR-GCK GRSQEGLILRNESLAPDEVTRRSGLPVSTRVRTAFDLGRHLERPEALARL
MAB_2184|M.abscessus_ATCC_1997 CRQQEGLIARNERIGADEITRISGLPVTHRVRTAFDLGRYQPRTRAMGCL
MSMEG_0850|M.smegmatis_MC2_155 GRPPAGLIVRNETLAADEVMRVAGLPVTTPARTAFDLARHLPRDEAVARI
MAV_4752|M.avium_104 TRAPDGVLIRRDGLCPGETQICDGLAVTTPERTAFDIGRRGAVRSAVVRL
TH_4125|M.thermoresistible__bu GRPPPRIIVRNERLDAADVTTVDDMLVTTPARTAFDLARHLPRDAAVRHL
: :: * : : : .: *: ***:*:.* :: :
Mb3741c|M.bovis_AF2122/97 DALMRATPFSRDDVLLLAKRHAGARGVRRLRDVLPLVDGGAASPKETWLR
Rv3714c|M.tuberculosis_H37Rv DALMRATPFSRDDVLLLAKRHAGARGVRRLRDVLPLVDGGAASPKETWLR
MMAR_0375|M.marinum_M DALMRATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRETWLR
MUL_4737|M.ulcerans_Agy99 DALMRATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRESWLR
Mvan_5526|M.vanbaalenii_PYR-1 DALMWNQPFSIDEVAELADRRPRVPGVGQLRDLLPLIDGGAASPRQSRLR
Mflv_1289|M.gilvum_PYR-GCK DALMWNQRYAIDDVLALAERHPRARGVTQLRELLPLVDGGAASPRESALR
MAB_2184|M.abscessus_ATCC_1997 DALMRNQVFALDEVAGLSQRYPKVRGVRQLRELLPLIDAGAQSPRESLIR
MSMEG_0850|M.smegmatis_MC2_155 DALAWTRRVTVDDVAALIERYPAARGIRAARAVLRLVDAGADSPRETWLR
MAV_4752|M.avium_104 DSLARATGFKADDVLRVAGAHPRSPGLRRLEAALGLVDPGAQSPRESYLR
TH_4125|M.thermoresistible__bu DALAGATGVCAADVLPLADRYRRARGLPRARVALDLMDGGAQSPRETRLR
*:* :* : *: . * *:* ** **::: :*
Mb3741c|M.bovis_AF2122/97 LLLIDAGLPVPTTQIPVVHRW-RNVGVLDMGWEKYMVAAEYDGDQHRSDR
Rv3714c|M.tuberculosis_H37Rv LLLIDAGLPVPTTQIPVVHRW-RNVGVLDMGWEKYMVAAEYDGDQHRSDR
MMAR_0375|M.marinum_M MVLIDAGLPVPVTQIPVHQNW-RLVAVLDMGWQKYQVAAEYDGDQHRFDR
MUL_4737|M.ulcerans_Agy99 MVLIDAGLPVPVTQIPVHQNW-RLVAVLDMGWQKYQVAAEYDGDQHRFDR
Mvan_5526|M.vanbaalenii_PYR-1 LWLLDCGFPRPQTQIPVLEGS-RPVAFLDMGWPEYQVAVEYDGDHHRKNR
Mflv_1289|M.gilvum_PYR-GCK LALIDSGFPKPETQIPVFAGT-RPIAFLDMGWEEYGVAVEYDGDHHRKDR
MAB_2184|M.abscessus_ATCC_1997 LQLRDAGLPRAQTQVPVFDGY-TPIAFLDIGWPQYLVAVEYDGDHHRRDR
MSMEG_0850|M.smegmatis_MC2_155 LRLTDAGLPPDSTQIPVVDERGRIVAILDMGWERHLVAVNYDGVFHQSDR
MAV_4752|M.avium_104 LLLIDAGLPRPQTQVPVPGADGLPVAYLDMGWPEWMVAVEYDGDHHRTDR
TH_4125|M.thermoresistible__bu LILVDDGLPRPRTQIGVSDGV--NEAFIDMGWDEPMVGLDYEGAHHSADR
: * * *:* **: * . :*:** . *. :*:* * :*
Mb3741c|M.bovis_AF2122/97 GRYVKDQRRLRKLAELGWIVIRVIAEDNPDDVVNRVRAALLARGWRP---
Rv3714c|M.tuberculosis_H37Rv GRYVKDQRRLRKLAELGWIVIRVIAEDNPDDVVNRVRAALLARGWRP---
MMAR_0375|M.marinum_M RQYARDQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALARRGHRET--
MUL_4737|M.ulcerans_Agy99 RQYAREQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALARRGHRET--
Mvan_5526|M.vanbaalenii_PYR-1 DQYVKDIARLRMLEALGWIVIRVIAEDRPAHWLERTEAALQSRGCRLAAT
Mflv_1289|M.gilvum_PYR-GCK RQYVKDIARLRMLEERGWSVVRVIAEDMPAAWLRRVADALRRKGCPLAWV
MAB_2184|M.abscessus_ATCC_1997 RQYVKDLARLRMLEERGWTVIRVIAEESPGAWIARTTAALRSRGCHIEID
MSMEG_0850|M.smegmatis_MC2_155 KRYVRDLKTLRALEDRGWIVIRVVAEDDIADVITRVAAAP-WLAPRLH--
MAV_4752|M.avium_104 RQYVKDIRRLEMLEQLGWVIVRVVAEDRPADIVRRVRAALAKSGVAPRLS
TH_4125|M.thermoresistible__bu RQYVHDIGRAELIVGQGWLDIRVVAEHSRRFILHRTREAFARRGWHLPKP
:*.:: . : ** :**:* . : *. * .
Mb3741c|M.bovis_AF2122/97 -----------
Rv3714c|M.tuberculosis_H37Rv -----------
MMAR_0375|M.marinum_M -----------
MUL_4737|M.ulcerans_Agy99 -----------
Mvan_5526|M.vanbaalenii_PYR-1 ELQLFVRTLAA
Mflv_1289|M.gilvum_PYR-GCK AG----KTIAA
MAB_2184|M.abscessus_ATCC_1997 EMQRSTRPFAA
MSMEG_0850|M.smegmatis_MC2_155 -----------
MAV_4752|M.avium_104 V----------
TH_4125|M.thermoresistible__bu V----------