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MSGRHRKPAPSAVNVAKIAFTGAVIGGGGLALAGQAGAATDGEWDQVARCESGGNWAINTGNGYHGGLQF SPGTWSGHGGGEYAPAAYLATKEEQIAVAERVLASQGKGAWPSCGGPLSAATPRNVVAEPPAPVDPVGLN GLLPPPPVDPFAPPPAPAPVDALAAPAPLPPAPEALPPAPAPAAPFDAMSAPAPLPPAPEALPPAPAPAA PFDAMSAPAPLPPAPEALPPAPVVDAANIAPLDAPLPPPAPVDAPPAQSAIIAAANWDTAPVPGEHPQLW SLGVDAPLQPAPVLPPAPAPAPAPAAVAAPAPDPLAPLGAVEVPAPAYDIANQAISGELPVPSEVPHLAS PDNLPPGTAMAPQGPRQSPNVTYLKEIWHAIQTQEISGADALLALTQRPLTTPDTPGGTPPIAPGAPGAP VAPLAGPAPAPAPVPAPAPVLPPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5049 | - | - | 100% (444) | FHA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3343 | - | 1e-28 | 38.40% (250) | FHA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3011 | - | 6e-28 | 48.34% (151) | hypothetical protein Mvan_3011 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0891c | rpfA | 2e-78 | 46.52% (402) | resuscitation-promoting factor RpfA |
| M. gilvum PYR-GCK | Mflv_1703 | - | 1e-176 | 69.67% (488) | transglycosylase domain-containing protein |
| M. tuberculosis H37Rv | Rv0867c | rpfA | 5e-90 | 48.97% (437) | resuscitation-promoting factor RpfA |
| M. leprae Br4923 | MLBr_02151 | - | 4e-52 | 58.56% (181) | hypothetical protein MLBr_02151 |
| M. abscessus ATCC 19977 | MAB_0869c | - | 7e-82 | 46.83% (410) | resuscitation-promoting factor RpfA |
| M. marinum M | MMAR_4665 | rpfA | 1e-105 | 54.00% (413) | resuscitation-promoting factor RpfA |
| M. avium 104 | MAV_0996 | - | 5e-68 | 60.81% (222) | resuscitation-promoting factor RpfA |
| M. smegmatis MC2 155 | MSMEG_5700 | - | 1e-157 | 64.02% (503) | secreted protein |
| M. thermoresistible (build 8) | TH_0979 | - | 2e-25 | 65.33% (75) | Probable resuscitation-promoting factor rpfB |
| M. ulcerans Agy99 | MUL_0283 | rpfA | 3e-87 | 66.02% (259) | resuscitation-promoting factor RpfA |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5049|M.vanbaalenii_PYR-1 ---MSGRHRKPAP--SAVNVAKIAFTGAVIGGGGLALAGQAGAATDGEWD
Mflv_1703|M.gilvum_PYR-GCK ---MSGRHRKPAS--SAKSVAKIAFTGAVIGGGGIALAGHAGAATDGEWD
MSMEG_5700|M.smegmatis_MC2_155 ---MSGRHRKPTSSSSAKNVAKIAFTGAVLGGGGLGMAGQAMAATDGEWD
MAV_0996|M.avium_104 ----------------------------MLGGGAIAMAGQAAAATDGEWD
MAB_0869c|M.abscessus_ATCC_199 ---MSGRHSKPSK--ASAKAAKVAVAGAGLVGGGLMMAATANAATDGEWD
Mb0891c|M.bovis_AF2122/97 ---MSGRHRKPTT--SNVSVAKIAFTGAVLGGGGIAMAAQATAATDGEWD
Rv0867c|M.tuberculosis_H37Rv ---MSGRHRKPTT--SNVSVAKIAFTGAVLGGGGIAMAAQATAATDGEWD
MMAR_4665|M.marinum_M ---MSGRHRKPTT--SNVSVAKIAFTGAVLGGGGIALAGHAAAATDGEWD
MUL_0283|M.ulcerans_Agy99 ---MSGRHRKPTT--SNVSVAKIAFTGAVLGGGGIALAGHAAAATDGEWD
MLBr_02151|M.leprae_Br4923 ---MSESYRKLTT--SSIIVAKITFTGAMLDG-SIALAGQASPATDSEWD
TH_0979|M.thermoresistible__bu VNVLHKIHENPSP-ALRLVVGALLVVLAAAGGYAVSAHKTVTLSVDGAPM
* .: . :.*.
Mvan_5049|M.vanbaalenii_PYR-1 QVARCESGGNWAINTGNGYHGGLQFSPGTWSGHGGGEYAPAAYLATKEEQ
Mflv_1703|M.gilvum_PYR-GCK RVASCESGGNWAINTGNGYHGGLQFSPSTWSGHGGGEFAPAAYLATKEEQ
MSMEG_5700|M.smegmatis_MC2_155 QVARCESGGNWAINTGNGYHGGLQFSPSTWRAHGGTEFAPAAYMATKEEQ
MAV_0996|M.avium_104 QVARCESGGNWGINTGNGYHGGVQFSASTWAAHGGGEYAPSAELATREQQ
MAB_0869c|M.abscessus_ATCC_199 QVARCESGGNWAINTGNGYQGGLQFSPSTWINSGGGQYAPSAHLATKEQQ
Mb0891c|M.bovis_AF2122/97 QVARCESGGNWSINTGNGYLGGLQFTQSTWAAHGGGEFAPSAQLASREQQ
Rv0867c|M.tuberculosis_H37Rv QVARCESGGNWSINTGNGYLGGLQFTQSTWAAHGGGEFAPSAQLASREQQ
MMAR_4665|M.marinum_M QVARCESGGNWAINTGNGYYGGVQFAQSTWASHGGGEYAPSAQLASREEQ
MUL_0283|M.ulcerans_Agy99 QVARCESGGNWAINTGNGYYGGVQFAQSTWASHGGGEYAPSAQLASREEQ
MLBr_02151|M.leprae_Br4923 QVARCESGGNWSINTGNGYLGGLQFSQGTWASHGGGEYAPSAQLATREQQ
TH_0979|M.thermoresistible__bu TVSTMKSR-VIDVVEENGFTVGER--DDLFPAAGERISADDTIVLRRSRP
*: :* : **: * : . : * * : : :..
Mvan_5049|M.vanbaalenii_PYR-1 IAVAERVLASQGKGAWPSCGGPLSAATPRNVVAEP---PAPVDPVGLNGL
Mflv_1703|M.gilvum_PYR-GCK IAVAERVLASQGKGAWPTCGKVLSAATPRNVVDEPPA-PAPVDPLGLNGV
MSMEG_5700|M.smegmatis_MC2_155 IAVAERVLASQGKGAWPTCGRGLSGATPRNVVAEP-E-PAPLDAPGVNGE
MAV_0996|M.avium_104 IAVAERVLATQGRGAWPVCGGPLSGPTPR---DVP-A-PAGLDAPGVNGV
MAB_0869c|M.abscessus_ATCC_199 IAVAEKVLAGQGRGAWPVCGRGLSGSTPRTAPAANIT-PAAHHEEQAAAE
Mb0891c|M.bovis_AF2122/97 IAVGERVLATQGRGAWPVCGRGLSNATPREVLPASAAMDAPLDAAAVNGE
Rv0867c|M.tuberculosis_H37Rv IAVGERVLATQGRGAWPVCGRGLSNATPREVLPASAAMDAPLDAAAVNGE
MMAR_4665|M.marinum_M IAVAERVLATQGRGAWPVCGHGLSAATPRDV-PAPAALDAPLDAPGINGE
MUL_0283|M.ulcerans_Agy99 IAVAERVLATQGRGAWPVCGHGLSAATPRDV-PPPAALDAPLDAPGINGE
MLBr_02151|M.leprae_Br4923 IAVAERVLATQGSGAWPACGHGLSGPSLQEVLPAGMG------APWINGA
TH_0979|M.thermoresistible__bu LEISLDGQKSEQ--VWTTASTVDEALAQLSMADKAPAAASRASRVPLAGM
: :. : .*. .. . : .
Mvan_5049|M.vanbaalenii_PYR-1 LPPP--PVDPFAPPP-----------------------------------
Mflv_1703|M.gilvum_PYR-GCK LPPPPAPLDPFAPPPP----------------------------------
MSMEG_5700|M.smegmatis_MC2_155 LPPP-APVDMLAAPM-----------------------------------
MAV_0996|M.avium_104 PQAP-----PADAPP-----------------------------------
MAB_0869c|M.abscessus_ATCC_199 PAPA-------PEPP-----------------------------------
Mb0891c|M.bovis_AF2122/97 PAPL-------APP------------------------------------
Rv0867c|M.tuberculosis_H37Rv PAPL-------APPPADPAPPVELAANDLPAPLGEPLPAAPADPAPPADL
MMAR_4665|M.marinum_M PAPL-------APP------------------------------------
MUL_0283|M.ulcerans_Agy99 PAPL-------APP------------------------------------
MLBr_02151|M.leprae_Br4923 PAPL-------APP------------------------------------
TH_0979|M.thermoresistible__bu SLPV-------VSPKT----------------------------------
. *
Mvan_5049|M.vanbaalenii_PYR-1 ------------------------------------------APAPVDAL
Mflv_1703|M.gilvum_PYR-GCK ----------------------------------------PPAPAPFDAL
MSMEG_5700|M.smegmatis_MC2_155 -------------------------------------------PAPEG--
MAV_0996|M.avium_104 --------------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 -------------------------------------------AEGDEQF
Mb0891c|M.bovis_AF2122/97 --------------------------------------------PADLAP
Rv0867c|M.tuberculosis_H37Rv APPAPADVAPPVELAVNDLPAPLGEPLPAAPADPAPPADLAPPAPADLAP
MMAR_4665|M.marinum_M --------------------------------------------------
MUL_0283|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
TH_0979|M.thermoresistible__bu -------------------------------------------------V
Mvan_5049|M.vanbaalenii_PYR-1 AAPAP--LPPAPEALP-------------PAPAP-AAPFDAMSAPAPLPP
Mflv_1703|M.gilvum_PYR-GCK AAPAPAPLPPAPETLPPAPVEQLAAPVPLPAPAPEAVPVDAMAAPAPLPP
MSMEG_5700|M.smegmatis_MC2_155 LPPAPEALPPAPEALPPAP--------EAPAPAPEALPP----APEALPP
MAV_0996|M.avium_104 --PAPVQLASFDRPAPP------------DAPAPDAPPP----APADLPP
MAB_0869c|M.abscessus_ATCC_199 VAEAPEAPAIDEAPAP------------EEAPAPEAQDVDFQSGPAPEEP
Mb0891c|M.bovis_AF2122/97 PAPADLAPPAPADLAPPVE----------LAVNDLPAPLGEP-----LPA
Rv0867c|M.tuberculosis_H37Rv PAPADLAPPAPADLAPPVE----------LAVNDLPAPLGEP-----LPA
MMAR_4665|M.marinum_M --PGDDVPP-PADPAPPVE----------LAANDVPAPADLPPAPEDLPP
MUL_0283|M.ulcerans_Agy99 --PGDDVPP-PADPAPPVE----------LAANDVPAPADLPPAPEDLPP
MLBr_02151|M.leprae_Br4923 --------P-PAEPAPPQP----------PADN-----------------
TH_0979|M.thermoresistible__bu HINDGGELRTVHLAAPTVAN----------LLEAAGAPLEQQDKVSPPPS
*
Mvan_5049|M.vanbaalenii_PYR-1 APEALP------PAPAPAAPFDAMSAPA----PLPPAPEALP----PAPV
Mflv_1703|M.gilvum_PYR-GCK APEALPPAPLDAPAPAQTVAFDAVAAPA----PLP-APEALPPAPLPAPA
MSMEG_5700|M.smegmatis_MC2_155 APEALPPAP-EAPAPAPEALPPAPEAPAPVAEALPPAPEALPPAPEAPPA
MAV_0996|M.avium_104 APADLP----------------------------------------PAPP
MAB_0869c|M.abscessus_ATCC_199 APAPEP------------APVDEAQAPA---------PELIAAPAPEAPV
Mb0891c|M.bovis_AF2122/97 APAELAP-------PADLAPASADLAPP-----------APADLAPPAPA
Rv0867c|M.tuberculosis_H37Rv APAELAP-------PADLAPASADLAPP-----------APADLAPPAPA
MMAR_4665|M.marinum_M APEDLAPPA-----PADLPPAPEDLPP------------APQDLPP-APE
MUL_0283|M.ulcerans_Agy99 APEDLAPPA-----PADLPPAPEDLPP------------APQDLPP-APE
MLBr_02151|M.leprae_Br4923 -----------------FPPTPGDVPS-----------------------
TH_0979|M.thermoresistible__bu APVTDGMHVEVTRVRVEKVTERLPLAPN--------NRRIEDETLNKSRT
Mvan_5049|M.vanbaalenii_PYR-1 VDAAN------IAPLDAPLP-----PPAPVDAPPAQSAIIAA------AN
Mflv_1703|M.gilvum_PYR-GCK PEAVP------FDALSAPAPVEPIVAPIPVDAPP--SAVVTA------VN
MSMEG_5700|M.smegmatis_MC2_155 PEALPPAPEAQIVDASLQVPADVPPAPPVEPAPPAPVDAVAAPEN---QN
MAV_0996|M.avium_104 ADATPPAP------------------PADAPAP-----------------
MAB_0869c|M.abscessus_ATCC_199 VDEAP--------------------APEEAPAPEAPAADDQVLP----YE
Mb0891c|M.bovis_AF2122/97 ELAPP--------------------APADLAP------------------
Rv0867c|M.tuberculosis_H37Rv ELAPP--------------------APADLAP------------------
MMAR_4665|M.marinum_M DVAAP--------------------APADLPPAPEDVAPPVELVGNDVPA
MUL_0283|M.ulcerans_Agy99 DVAAP--------------------APADLP-------------------
MLBr_02151|M.leprae_Br4923 PLARP---------------------------------------------
TH_0979|M.thermoresistible__bu IVEDPG-------------------RPGVQDVTFAVSKVN----------
Mvan_5049|M.vanbaalenii_PYR-1 WDTAPVPG-EHPQLWSLGVDAPLQPAPVLPP---APAPAPAP---AAVAA
Mflv_1703|M.gilvum_PYR-GCK WDTAPAPAPGDPQMWSLGLDAPLQPAPVTP-----PLPAPAP---ETVAA
MSMEG_5700|M.smegmatis_MC2_155 WDQAPAPA-DQPQTWALHVGGPLPLDPVLPAPAPAPAPAPAPGAPAAVAA
MAV_0996|M.avium_104 --------------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 LQSGPAPAEPAPAPEPAPAPAAAPEIPLPAG---VPDAADIG----FAAG
Mb0891c|M.bovis_AF2122/97 -----------------------------------PAAVNEQTAPGDQPA
Rv0867c|M.tuberculosis_H37Rv -----------------------------------PAAVNEQTAPGDQPA
MMAR_4665|M.marinum_M PVDLPPAPEDLPPAPEDLAPPAPADLPPAPEDLAPPAPADLPPAPEDLAP
MUL_0283|M.ulcerans_Agy99 -----------------------------------PAPADLPPAPEDLAP
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
TH_0979|M.thermoresistible__bu -----------------------------------GVETGRLPVANVIVE
Mvan_5049|M.vanbaalenii_PYR-1 PAPDPLAPLGAVEVPAPAYDIANQAISGELPVPSEVPHLASPDNLPPGTA
Mflv_1703|M.gilvum_PYR-GCK PAPVVGVPAGQAG-PVPA-------------APAEVPHLVSPDNPPPGTT
MSMEG_5700|M.smegmatis_MC2_155 PAPDPLAPAPNADVAPTP--------------PEGVPHLASPENLPPGTT
MAV_0996|M.avium_104 ---------------------------------DGDFHGFVPAGMPDHVS
MAB_0869c|M.abscessus_ATCC_199 KAAFDAGPVASNGIPTSP-----------EAVAGVVRHLPDPNNLPPGTT
Mb0891c|M.bovis_AF2122/97 TAPGGPVGLATDLELPEPD-----------PQPADAPPPGDVTEAPAETP
Rv0867c|M.tuberculosis_H37Rv TAPGGPVGLATDLELPEPD-----------PQPADAPPPGDVTEAPAETP
MMAR_4665|M.marinum_M PAPADLPPAPEDLAPPAPADLP-PAPEDLPPAPEDLPPPADADNPPVDVH
MUL_0283|M.ulcerans_Agy99 ---------------------------------------------PVDVH
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
TH_0979|M.thermoresistible__bu PARDGVLRVGAKPGTEVPP-------------ITNLAIWEALARCEAGGN
Mvan_5049|M.vanbaalenii_PYR-1 MAP-QGPRQSPNVTYLKEIWHAIQTQEISGADALLALTQRPLTTPDTPGG
Mflv_1703|M.gilvum_PYR-GCK VTP-QGPQQSPNVTYLKEIWHAIQTQEISGSDALLALTQRPLTANG--GG
MSMEG_5700|M.smegmatis_MC2_155 ETPDQIPGQGPNMTYLREIWHAIQTQDISGKDALLALTQRPLTTPDVPGG
MAV_0996|M.avium_104 EAG-----------YTQRLWEAIRAQDVQGNDALDALVQ-----------
MAB_0869c|M.abscessus_ATCC_199 DVA---PGDSRGVSYLKDIVFAMQTQDVKASDAILALAQR----------
Mb0891c|M.bovis_AF2122/97 QVS--------NIAYTKKLWQAIRAQDVCGNDALDSLAQPYVIG------
Rv0867c|M.tuberculosis_H37Rv QVS--------NIAYTKKLWQAIRAQDVCGNDALDSLAQPYVIG------
MMAR_4665|M.marinum_M EAS--------TVAYTKKLWQAIVGQNISGNDALDALAQPTVFA------
MUL_0283|M.ulcerans_Agy99 EAS--------TVAYTKKLWQAIVGQNISGNDALDALAQPAVFA------
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
TH_0979|M.thermoresistible__bu WAINTGNGYYGGVQFDQNTWERNGGLRYAPRADLATKEEQIAIAEVTRAR
Mvan_5049|M.vanbaalenii_PYR-1 TPP---IAP----GAPG-APVAPLAG-PAPAPAP--------VPAPAPVL
Mflv_1703|M.gilvum_PYR-GCK PAP---MAPV---GAPAPAPEAPVQGAAAPLPAPA-------VPAPAPVL
MSMEG_5700|M.smegmatis_MC2_155 AAPNRPVAPPPAPGDPALAPAPAPLGAPAPAPAPEPAPVGAPAPVGAPVP
MAV_0996|M.avium_104 -----------------------------PAPSA----------------
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0891c|M.bovis_AF2122/97 --------------------------------------------------
Rv0867c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4665|M.marinum_M --------------------------------------------------
MUL_0283|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
TH_0979|M.thermoresistible__bu QGWGAWPTCSARLGVR----------------------------------
Mvan_5049|M.vanbaalenii_PYR-1 PPA
Mflv_1703|M.gilvum_PYR-GCK PPA
MSMEG_5700|M.smegmatis_MC2_155 PPA
MAV_0996|M.avium_104 ---
MAB_0869c|M.abscessus_ATCC_199 ---
Mb0891c|M.bovis_AF2122/97 ---
Rv0867c|M.tuberculosis_H37Rv ---
MMAR_4665|M.marinum_M ---
MUL_0283|M.ulcerans_Agy99 ---
MLBr_02151|M.leprae_Br4923 ---
TH_0979|M.thermoresistible__bu ---