For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RVRRKMSPSMNRISVTTLAALGMVWPFLFYGAPAAAEPSPGVPCLEILQQLAAAPPSVPETLDTAANALN NVVPEAAPALPPVPVAEVVHGLTALAAPGPVPPVDAAPLAAPPVPPVDAAPLAAPLVQAAAGPVPAAAPI PVVAPPIPAVIPLAPPVPVVAPPPAVPVAAPVEAVLASAPEPVAPAPVPPAPGEAAPVELAAAPPPVEPA PPAPPEPPPTAPTDVAPAVAEPVAPEPVMAPAAAEPTPAAVAPVEPGPAPVELVAAAEPAPIMEPAAAPV ESAPVFHAAAVPPALPGPVVPVVPAGVPVPVAPVGVPVPVVPTGAPAAVPAPPLGLPAVPLGDAVPGVPF LPATLPIPQDLVCEGTAWSAGRTAPEGDAAALDAPPGQRRDQW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3343 | - | - | 100% (394) | FHA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2552 | - | 8e-39 | 33.56% (447) | hypothetical protein Mvan_2552 |
| M. vanbaalenii PYR-1 | Mvan_5049 | - | 1e-28 | 38.40% (250) | FHA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2108 | - | 8e-22 | 29.13% (333) | hypothetical protein Mb2108 |
| M. gilvum PYR-GCK | Mflv_3843 | - | 1e-35 | 33.87% (437) | hypothetical protein Mflv_3843 |
| M. tuberculosis H37Rv | Rv0867c | rpfA | 4e-26 | 35.21% (284) | resuscitation-promoting factor RpfA |
| M. leprae Br4923 | MLBr_00048 | - | 1e-12 | 27.41% (259) | hypothetical protein MLBr_00048 |
| M. abscessus ATCC 19977 | MAB_2960 | - | 3e-19 | 32.16% (255) | hypothetical protein MAB_2960 |
| M. marinum M | MMAR_5451 | - | 2e-31 | 36.74% (313) | hypothetical protein MMAR_5451 |
| M. avium 104 | MAV_1296 | - | 5e-20 | 36.32% (212) | hypothetical protein MAV_1296 |
| M. smegmatis MC2 155 | MSMEG_5700 | - | 6e-29 | 33.51% (376) | secreted protein |
| M. thermoresistible (build 8) | TH_3807 | - | 4e-13 | 32.33% (232) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1004 | - | 1e-25 | 35.86% (290) | hypothetical protein MUL_1004 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1296|M.avium_104 -------------MATTWILSKGLAAVVTASVAALGLCPGAAADPAAAPQ
MUL_1004|M.ulcerans_Agy99 -------------MASTWSLSKGLAAVVVTSAAAFGLCPAAAADP-AAPQ
Mvan_3343|M.vanbaalenii_PYR-1 --------MRVRRKMSPSMNRISVTTLAALGMVWPFLFYGAPAAAEPSPG
Mflv_3843|M.gilvum_PYR-GCK --------------MSRTKKSIVVVMMGSAGLFLSAPLLGPAANATPTRG
Rv0867c|M.tuberculosis_H37Rv ------------MSGRHRKPTTSN--VSVAKIAFTGAVLGGGGIAMAAQA
MSMEG_5700|M.smegmatis_MC2_155 ------------MSGRHRKPTSSSSAKNVAKIAFTGAVLGGGGLGMAGQA
MLBr_00048|M.leprae_Br4923 ------------MAADYDKLFRLDDGAYASPDQAAEQLFDDAPLYPPPII
MMAR_5451|M.marinum_M ------------MPADYDELFQPAEGSGPPDDETGQTFFDPGTAYPPPVK
TH_3807|M.thermoresistible__bu ------------MRATRKLITSSVIAAGGAVAVALTCSATAAAQPAPAPA
MAB_2960|M.abscessus_ATCC_1997 -----MTTVPSPAEDTAMRMWEFPEENPEPPARWGKYVPGEPQLRAAAFG
Mb2108|M.bovis_AF2122/97 MAGDLPPGRWSALLVGAWWPARPDAPMAGVTYWRKAAQLKRNEANDLRNE
MAV_1296|M.avium_104 P---------------------APPPNAAPQLPGLPALSQLSPLIQQAAT
MUL_1004|M.ulcerans_Agy99 P---------------------NP----NPQLPGLPALAQLSPIIQQAAG
Mvan_3343|M.vanbaalenii_PYR-1 ----------------------VPCLEILQQLAAAPPSVPETLDTAANAL
Mflv_3843|M.gilvum_PYR-GCK G---------------------VPCVGILQQIVTRPGEIPQALTDTARSF
Rv0867c|M.tuberculosis_H37Rv T---------------------AATDGEWDQVARCESGGNWSINTGNGYL
MSMEG_5700|M.smegmatis_MC2_155 M---------------------AATDGEWDQVARCESGGNWAINTGNGYH
MLBr_00048|M.leprae_Br4923 P------------------------TCTTTPNGEVASPMP----------
MMAR_5451|M.marinum_M PNGDGHSAPKDWSRAFPPAEDESPSDSAEPAAGPAKSPLPPMPIGGPAPT
TH_3807|M.thermoresistible__bu P---------------------SPGVPFMDQLATAAANAPAILQSAAAAL
MAB_2960|M.abscessus_ATCC_1997 TLVG-----------------LLVAVLMGAAYAAQPGASLWALNKTIFPT
Mb2108|M.bovis_AF2122/97 RSLLAVNQGRTADDLLERYWRGEQRLATIAHQCEVKSDQSEQVADAVNYL
MAV_1296|M.avium_104 DP--------------------------QQATQLLMAA---------AQA
MUL_1004|M.ulcerans_Agy99 NP--------------------------EQATQLLMAA---------AQA
Mvan_3343|M.vanbaalenii_PYR-1 N-------------------------------NVVPEA---------APA
Mflv_3843|M.gilvum_PYR-GCK TEPPKPAPPVVRPPASSSSSAGTPPVPGRPPASVVTPS---------SGA
Rv0867c|M.tuberculosis_H37Rv GG------------------------LQFTQSTWAAHG---------GGE
MSMEG_5700|M.smegmatis_MC2_155 GG------------------------LQFSPSTWRAHG---------GTE
MLBr_00048|M.leprae_Br4923 -----------------------------DWSEQLPPN-------PPAAS
MMAR_5451|M.marinum_M PPEPPPAPPELPPAPPEPPPARPEAPPQAPTAEAEPPDEAIPVSGPPPGG
TH_3807|M.thermoresistible__bu GG------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 HS--------------------------QDIAVRAVVSDLKNAQDILGNN
Mb2108|M.bovis_AF2122/97 RDRLTEIAQSGNQQINQILAGKGPIEAKVAAVNAVIEQSNAMADHVGATA
MAV_1296|M.avium_104 FSHNPTAPTE------------------------------SKNVAAA---
MUL_1004|M.ulcerans_Agy99 FAHNPAAPTE------------------------------SRNVASS---
Mvan_3343|M.vanbaalenii_PYR-1 LPPVP-----------------------------------VAEVVHG---
Mflv_3843|M.gilvum_PYR-GCK TPPVPPSPGTPASTSTRGGTPPVPPAPPAPAGTPASGATPPAPPVPG---
Rv0867c|M.tuberculosis_H37Rv FAPSAQLASR------------------------------EQQIAVG---
MSMEG_5700|M.smegmatis_MC2_155 FAPAAYMATK------------------------------EEQIAVA---
MLBr_00048|M.leprae_Br4923 KSPLPPMPIG---------------------------SSVQPP-------
MMAR_5451|M.marinum_M KSPLPPMPIGGPPPASPEPPAAPPEPTAPAEPPQPPEAAAQPPQAVEEQA
TH_3807|M.thermoresistible__bu --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 KQPSPDQLTQAR--------------------------SSLNEAKQG---
Mb2108|M.bovis_AF2122/97 MSNIIDATQR-----------------------------VFDETIGGDAH
MAV_1296|M.avium_104 -----VNQFVAEPGSPVPNG------------------------------
MUL_1004|M.ulcerans_Agy99 -----VNQFVQEPVNPAPGSPPLGVP------------------------
Mvan_3343|M.vanbaalenii_PYR-1 -----LTALAAPG----PVPPVDAAP------------------------
Mflv_3843|M.gilvum_PYR-GCK -----VPAVTSTGGGTPPVPPVPGAPVGAPVANPGLPTPPVPGAPVFGDG
Rv0867c|M.tuberculosis_H37Rv -----ERVLATQGRGAWPVCGRGLSN------------------------
MSMEG_5700|M.smegmatis_MC2_155 -----ERVLASQGKGAWPTCGRGLSG------------------------
MLBr_00048|M.leprae_Br4923 ------PASSESPRAPMPVSAPPRSPAAS---------------------
MMAR_5451|M.marinum_M HATAEPPAAPNPPRPPMPIGGPPPTPPAAPEPQQDIAEEPAPAAA-----
TH_3807|M.thermoresistible__bu --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 ----LEFVSDSDERTSLQNLYLQLNQQLR---------------------
Mb2108|M.bovis_AF2122/97 TWLRDHGVSLDAPARPRPVTAEDMTSMTANSPAG----------------
MAV_1296|M.avium_104 -----------------------------VTPPDGAPVQHVP--------
MUL_1004|M.ulcerans_Agy99 ---------------------APAAAPVEVAPPASAPVPHVP--------
Mvan_3343|M.vanbaalenii_PYR-1 --------------------LAAPPVPPVDAAPLAAPL------------
Mflv_3843|M.gilvum_PYR-GCK GAVLPPLPPAPAGPAGGPAGLVAPPAPPVPGGPAAVPAGVALPPAPPGAP
Rv0867c|M.tuberculosis_H37Rv ---------------------ATPREVLPASAAMDAPLD-----------
MSMEG_5700|M.smegmatis_MC2_155 ---------------------ATPRNVVAE--PEPAPLD-----------
MLBr_00048|M.leprae_Br4923 ---------------------LMPISEPPQWPP--AEAPEHQ--------
MMAR_5451|M.marinum_M ---------EAPAAPPKSPLPPMPVSGPPPEPPELPPAPPEP--------
TH_3807|M.thermoresistible__bu --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 ---------------------QYTPEQAQQLPALPAPPGVNTDTN-----
Mb2108|M.bovis_AF2122/97 --------------SPFGAAPSAPSHSTTTSGPPTAPTPTSPFG------
MAV_1296|M.avium_104 ----------------------------------------------ATGI
MUL_1004|M.ulcerans_Agy99 ----------------------------------------------APGA
Mvan_3343|M.vanbaalenii_PYR-1 ----------------------------------------------VQAA
Mflv_3843|M.gilvum_PYR-GCK GAPVFGEAGAAPSGAAAPVAPAAGSGGAGGAGGGSGIGGPGGGGAPVEGT
Rv0867c|M.tuberculosis_H37Rv ----------------------------------------------AAAV
MSMEG_5700|M.smegmatis_MC2_155 ----------------------------------------------APGV
MLBr_00048|M.leprae_Br4923 -------------------------------------------FAKAEPP
MMAR_5451|M.marinum_M -------------------------------------------TASAEPP
TH_3807|M.thermoresistible__bu -----------------------------------------------TNT
MAB_2960|M.abscessus_ATCC_1997 ---------------------------------------------LAANI
Mb2108|M.bovis_AF2122/97 ----------------------------------------TAPMVLSSSS
MAV_1296|M.avium_104 EPGLQAHLPTGIDPAHAAGPAPAAA-------------------------
MUL_1004|M.ulcerans_Agy99 EPGTLAHLPAGIDPAHAAGPAPVAAPA-----------------------
Mvan_3343|M.vanbaalenii_PYR-1 AGPVPAAAP-------IPVVAPPIP--------AVIP-------------
Mflv_3843|M.gilvum_PYR-GCK GGAVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGVVPPPAPPAPAPPAGG
Rv0867c|M.tuberculosis_H37Rv NGEPAPLAPP----PADPAPPVELAAN-----------------------
MSMEG_5700|M.smegmatis_MC2_155 NGELPPPAPVDMLAAPMPAPEGLPPAP-----------------------
MLBr_00048|M.leprae_Br4923 SVPIPINEPS------PAKPATPMPMTP----------------------
MMAR_5451|M.marinum_M QPPQSVEEQAHATAEPPAAPKPTRPPMP----------------------
TH_3807|M.thermoresistible__bu MPSAPVVAPPPAATAQITVPQPALPAT-----------------------
MAB_2960|M.abscessus_ATCC_1997 GPAAPASSPPPSWGYATAASAPAPAAES----------------------
Mb2108|M.bovis_AF2122/97 TSSGPPTAPTPTSPFGTAPMPPGPPPPG----------------------
. .
MAV_1296|M.avium_104 --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 ----GAPPAS----------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 ----LAPPVP------------VVAPP-----------------------
Mflv_3843|M.gilvum_PYR-GCK LGGAVPPPVPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGA
Rv0867c|M.tuberculosis_H37Rv ---DLPAPLG-------------EPLP-----------------------
MSMEG_5700|M.smegmatis_MC2_155 ---EALPPAP-------------EALP-----------------------
MLBr_00048|M.leprae_Br4923 --IDGSQRTP-------------VTSPE----------------------
MMAR_5451|M.marinum_M --IGGPPPTPEPQQGAPQPHQDIAEEPN----------------------
TH_3807|M.thermoresistible__bu ----VAP-------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 --YLVPPPAG---------------------------------------I
Mb2108|M.bovis_AF2122/97 ---TVSPPLP----------------------------------------
MAV_1296|M.avium_104 --APSAPAPAATPPSAP---------------------------------
MUL_1004|M.ulcerans_Agy99 APAPAAAAPASAPGTAP---------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 PAVPVAAPVEAVLASAP---------------------------------
Mflv_3843|M.gilvum_PYR-GCK PGVPVVDEAGVVTPPAPG-------------------------------G
Rv0867c|M.tuberculosis_H37Rv AAPADPAPPADLAPPAPA-------------------------------D
MSMEG_5700|M.smegmatis_MC2_155 PAPEAPAPAPEALPPAPE-------------------------------A
MLBr_00048|M.leprae_Br4923 PSLAEFEAQPPATPKPSL--------------------------------
MMAR_5451|M.marinum_M PAAAEAPAAPPKSPRPPMPVNGPAPTRPEPPLPPGPPRRRAQPPTAPPNQ
TH_3807|M.thermoresistible__bu ATAPIIKQPGTVTPTAPG--------------------------------
MAB_2960|M.abscessus_ATCC_1997 PVDPVPDWPAPVAPPLTPN-------------------------------
Mb2108|M.bovis_AF2122/97 PSAPAVGVGGPSVPAAGMP-------------------------------
MAV_1296|M.avium_104 -----------APAAAP---------------------------------
MUL_1004|M.ulcerans_Agy99 -----------APAAAPGPA------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 ------------EPVAP---------------------------------
Mflv_3843|M.gilvum_PYR-GCK PGVPTGGEGGVVTPPAPGAPGAPVVDEAGVVTPPAPGGPGVPAVGDTAVV
Rv0867c|M.tuberculosis_H37Rv VAPPVELA--VNDLPAPLG-------------------------------
MSMEG_5700|M.smegmatis_MC2_155 LPPAPEALPPAPEAPAPAP-------------------------------
MLBr_00048|M.leprae_Br4923 --LPRPMS-SPPEAPRPS--------------------------------
MMAR_5451|M.marinum_M PGQPKPISGHPPPPPRPAAFAPPARGATPNRHESAEPPPPRRVRIGGPPQ
TH_3807|M.thermoresistible__bu --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 -----LLDLGGYDPSWSLLYGYNVLDWFNWGLSGFNRYGYDFMGFDRWGY
Mb2108|M.bovis_AF2122/97 -----PAAAAATAPLSPQSLG-----------------------------
MAV_1296|M.avium_104 ------------------------------------------APGPVQPA
MUL_1004|M.ulcerans_Agy99 --------------------------------------PAAPAPAPAAAA
Mvan_3343|M.vanbaalenii_PYR-1 ---------------------------------------APVPPAP--GE
Mflv_3843|M.gilvum_PYR-GCK TPPAPGAPGTPAVNSVETFSPPAPPAATPPSSGSVETFSPPAPPAPGTGT
Rv0867c|M.tuberculosis_H37Rv ---------------------------------------EPLPAAP--AD
MSMEG_5700|M.smegmatis_MC2_155 ---------------------------------------EALPPAP--EA
MLBr_00048|M.leprae_Br4923 ----------ANQHSRHARRGHHHRDETQQAN-------PASATEPMIAP
MMAR_5451|M.marinum_M PPGPPEAESEAPRHSRHARRTHRYRPEPETDDLEATAVRPLPTREPMRRN
TH_3807|M.thermoresistible__bu ------------------------------------------VPLPTAEA
MAB_2960|M.abscessus_ATCC_1997 DRWGYDRWGYDRWGYNWDGYNWSGYNRDGRDRDGRNEWGQIHDDDPRDQG
Mb2108|M.bovis_AF2122/97 ----------------------QSFTTGMTTGTPAAAGAQALSAGALHAA
.
MAV_1296|M.avium_104 TVPAAAPVPPPPAPAAAAP--------------------------ATPG-
MUL_1004|M.ulcerans_Agy99 PAPAPAPAAPPAAPVAAPV--------------------------AAPAP
Mvan_3343|M.vanbaalenii_PYR-1 AAPVELAAAPPPVEP------------------------------APPAP
Mflv_3843|M.gilvum_PYR-GCK NSTVEISTPPPPGTPGLPSEGSTTYTTPPTPEITLNPANSGIDIATPPAP
Rv0867c|M.tuberculosis_H37Rv PAPPADLAPPAPADL------------------------------APPAP
MSMEG_5700|M.smegmatis_MC2_155 PAPVAEALPPAPEALPPAPE-------------------------APPAP
MLBr_00048|M.leprae_Br4923 --------RARTAELRQ-----------------------APHAAAEPAP
MMAR_5451|M.marinum_M GPAADESSTASFAWLQQSQP---------TLDRPSGPMPAAPGAPVESAP
TH_3807|M.thermoresistible__bu TLPNVAGTPVPQQVS-----------------------------------
MAB_2960|M.abscessus_ATCC_1997 WYDRYHPYRQYYDWKFQNTN------------PVYSRSLWDQSHGIDPSQ
Mb2108|M.bovis_AF2122/97 TEPLPPPAPPPTTPTVTTPT----------------------VATATTAG
MAV_1296|M.avium_104 --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK GLPGAPLEATANITTPGTPGVPGAPVNSSIDVATPGEVGVPAAPIERSMT
Rv0867c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00048|M.leprae_Br4923 ---------------TQHLTRPDGLVSH----------------------
MMAR_5451|M.marinum_M GRADGRRARRRAESRTSAASTPSPLVPTRAQPPGP----------TRAQP
TH_3807|M.thermoresistible__bu --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------Y
Mb2108|M.bovis_AF2122/97 --------------------------------------------IPHIPD
MAV_1296|M.avium_104 --------------------APDAAPAPAAAPGFG---------------
MUL_1004|M.ulcerans_Agy99 ---VPAPAPAAAPAPEAAAPAPAPAPAPAAAPGFG---------------
Mvan_3343|M.vanbaalenii_PYR-1 ---PEPP--PTAPTDVAPAVAEPVAP----EPVM----------------
Mflv_3843|M.gilvum_PYR-GCK VTTPDTPGAPGAPANAAVDVATPPAPGVPGAPVVGEAGVTTPGAPGAPGA
Rv0867c|M.tuberculosis_H37Rv ADLAPPAPADLAPP-VELAVNDLPAPLGEPLPAAPAELAPPA--------
MSMEG_5700|M.smegmatis_MC2_155 EALPPAPEAQIVDASLQVPADVPPAPPVEPAPPAPVDAVAAPENQN----
MLBr_00048|M.leprae_Br4923 -RTALHDSTATSAIGVQTGRSTGAKKPSKVVAKRGWRHWVHTVTRINLG-
MMAR_5451|M.marinum_M PRTAAPAQPATEPLPDAGAPAEQSKKPNKPVPQRGWRRWVYAVTRINFG-
TH_3807|M.thermoresistible__bu ----------------------LPADVSALLPAAG---------------
MAB_2960|M.abscessus_ATCC_1997 RDWNLNRNWDNPLERDWSPVARVADRPLLAEPVVNLDASLAQFITDD---
Mb2108|M.bovis_AF2122/97 SAPTPSPAPIAPPTTDNASAMTPIAPMVANGPPASPAPPAAAPAG-----
.
MAV_1296|M.avium_104 --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK PANAAVDVATPPAPGVPGAPVVGEAAVTTPGAPGVPGVPAGGDAGVVTPP
Rv0867c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00048|M.leprae_Br4923 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
TH_3807|M.thermoresistible__bu --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2108|M.bovis_AF2122/97 --------------------------------------------------
MAV_1296|M.avium_104 ------------------------------------------ADAPPTQD
MUL_1004|M.ulcerans_Agy99 ------------------------------------------PDAPPTQD
Mvan_3343|M.vanbaalenii_PYR-1 --------------------------------------------APAAAE
Mflv_3843|M.gilvum_PYR-GCK APGVPGAPVVGEAGVTTPGAPGVPGVPAGGDAGVVTPPAPGVPGAPAATE
Rv0867c|M.tuberculosis_H37Rv ------------------------------------------DLAPASAD
MSMEG_5700|M.smegmatis_MC2_155 -----------------------------------------WDQAPAPAD
MLBr_00048|M.leprae_Br4923 ----------------------------------------LSPDERYELD
MMAR_5451|M.marinum_M ----------------------------------------LSPDEKYELD
TH_3807|M.thermoresistible__bu --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 ------------------------------------------KSARSSQD
Mb2108|M.bovis_AF2122/97 ------------------------------------------PLPAYGAD
MAV_1296|M.avium_104 FMY----------------------------------------PSIGTNC
MUL_1004|M.ulcerans_Agy99 FMY----------------------------------------PSIGTNC
Mvan_3343|M.vanbaalenii_PYR-1 P------------------------------------------TPAAVAP
Mflv_3843|M.gilvum_PYR-GCK AGLATPPGPGAPGAPVVGDAGVATPPGPGVPGAPIVDEAGLATPPAPVAP
Rv0867c|M.tuberculosis_H37Rv L------------------------------------------APPAPAD
MSMEG_5700|M.smegmatis_MC2_155 Q------------------------------------------PQTWALH
MLBr_00048|M.leprae_Br4923 LRTRVR------------------------------------RPPRGSYQ
MMAR_5451|M.marinum_M LRTRIG------------------------------------RKPRGSYQ
TH_3807|M.thermoresistible__bu --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 LIKDLSN----------------------------------KSARNFSKE
Mb2108|M.bovis_AF2122/97 LRPPVTTPP--------------------------------ATPPTPTGP
MAV_1296|M.avium_104 LAD---------------------------GSSAIATALS----------
MUL_1004|M.ulcerans_Agy99 LAD---------------------------GSNIIATALS----------
Mvan_3343|M.vanbaalenii_PYR-1 VE---------------------------PGPAPVELVA-----------
Mflv_3843|M.gilvum_PYR-GCK VEGAGGAVPPAGPPPAPVFGDAGAPVEAAAGGAPVEAAAGVTGGGSVAGA
Rv0867c|M.tuberculosis_H37Rv LA----------------------------PPAPAELAP-----------
MSMEG_5700|M.smegmatis_MC2_155 VG----------------------------GPLPLDPVL-----------
MLBr_00048|M.leprae_Br4923 IGILG--------------------LKGGAGKTTVTVTLG----------
MMAR_5451|M.marinum_M IAILG--------------------LKGGAGKTTTTVTLG----------
TH_3807|M.thermoresistible__bu --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 LAAQTPRP---------------DRSTGPDAPAAVKPAAPP---------
Mb2108|M.bovis_AF2122/97 ISGAAVTP-----------------SSPAAGGSLMSPVVN----------
MAV_1296|M.avium_104 --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK GAGGGAGGAAGGAGVEGASGAVGAAGGPGAGAAPAAAGGAAPGGAPGGPV
Rv0867c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00048|M.leprae_Br4923 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
TH_3807|M.thermoresistible__bu --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2108|M.bovis_AF2122/97 --------------------------------------------------
MAV_1296|M.avium_104 -------------------------------------VAGPAKIPAPGPG
MUL_1004|M.ulcerans_Agy99 -------------------------------------VAGPATIPTPGPG
Mvan_3343|M.vanbaalenii_PYR-1 -------------------------------------AAEPAPIMEPAAA
Mflv_3843|M.gilvum_PYR-GCK AGGGPVGGPGALPAPGAPIVGEAGVVSPPAPGVPGGAAAVPAGAVTPPAP
Rv0867c|M.tuberculosis_H37Rv --------------------------------------PAPADLAPPAAV
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------PAPAPAPAPAPA
MLBr_00048|M.leprae_Br4923 --------------------------------------SMFARVRNDRIL
MMAR_5451|M.marinum_M --------------------------------------TTLTHVRGDRIL
TH_3807|M.thermoresistible__bu --------------------------------------SQLANLMPAVP-
MAB_2960|M.abscessus_ATCC_1997 ------------------------------------VLTAPVPVVPPKEV
Mb2108|M.bovis_AF2122/97 ------------------------------------KSTAPATTQAQPSN
. .
MAV_1296|M.avium_104 PGQTAYVFT---------------------------AVGTPGP-------
MUL_1004|M.ulcerans_Agy99 PGQTAYVFT---------------------------AVGTPGP-------
Mvan_3343|M.vanbaalenii_PYR-1 PVESAPVF---------------HAAAVP--------PALPG--------
Mflv_3843|M.gilvum_PYR-GCK GVPGAPVFGEAGVVTPPAPGVPGGAAAVPAGVVTPPAPGVPGGAAAVPAG
Rv0867c|M.tuberculosis_H37Rv NEQ--TAP---------------GDQPAT-------APGGPVG-------
MSMEG_5700|M.smegmatis_MC2_155 PGA--PAA---------------VAAPAP-------DPLAPAP-------
MLBr_00048|M.leprae_Br4923 VVDADTSCGNLADRAGRFSEANIADLLADKDVKSYNDIRTHTSVN-----
MMAR_5451|M.marinum_M VLDADPGAGNLAERSGRSSPSSIADLLADPRLSHYNDVRAHTSVN-----
TH_3807|M.thermoresistible__bu -----------------------------------NEPGAPAP-------
MAB_2960|M.abscessus_ATCC_1997 PADFTPPSLPPVAPVTPAPRTTSSAPSSAPSTEPSHTPEPSSEPPANG--
Mb2108|M.bovis_AF2122/97 PTPPLASATAAATTGAAAGDTSRRAAEQQRLRRILDTVARQEPGLSWAAG
MAV_1296|M.avium_104 ----------------------AEEQKLPLNVTWVNLTTG----------
MUL_1004|M.ulcerans_Agy99 ----------------------AEVQRLPLNVTWVNLTTG----------
Mvan_3343|M.vanbaalenii_PYR-1 ----------------------PVVPVVPAG-VPVPVAPVGVPVPVVP--
Mflv_3843|M.gilvum_PYR-GCK AVTPPAPGVPGAPVFGDAGVATPPVPGVPGGGTTVPAASVTPPAPGVPGG
Rv0867c|M.tuberculosis_H37Rv ---------------------LATDLELPE---PDPQPADAPPP---GD-
MSMEG_5700|M.smegmatis_MC2_155 ---------------------NADVAPTPPEGVPHLASPENLPP---G--
MLBr_00048|M.leprae_Br4923 ---------------------AVNLEVLPAAEYSTAQHALSGEDWNFAAA
MMAR_5451|M.marinum_M ---------------------AANLEILPTAEYTSAQRGLSGEDLRSAVD
TH_3807|M.thermoresistible__bu ----------------------ATPPMLPSGLFPTSALP-----------
MAB_2960|M.abscessus_ATCC_1997 --------------------TTSNPGPTPTSVAPAPTQKDESSAPVTTAV
Mb2108|M.bovis_AF2122/97 ---LRDNGQTTLLVTDLASGWIPPHIRLPAHITLLEPAPRRRHATVTDLL
*
MAV_1296|M.avium_104 --------------------------------------KSGTVALKPR--
MUL_1004|M.ulcerans_Agy99 --------------------------------------KSGSVTLKPR--
Mvan_3343|M.vanbaalenii_PYR-1 ---------------------------------------TGAPAAVP---
Mflv_3843|M.gilvum_PYR-GCK ASTVPGNAGTPSTPGLPPGSTDTYINYPAPPVPPTPPNSTGVSAGTPGSP
Rv0867c|M.tuberculosis_H37Rv --------------------------------------VTEAPAETP---
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------TTETPDQIPG--
MLBr_00048|M.leprae_Br4923 TVSKYYN---------------------------VMLADCGVGLFDPVTR
MMAR_5451|M.marinum_M TVSKFYN---------------------------LVLADCGAGLFDPVTL
TH_3807|M.thermoresistible__bu --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 TP------------------------------------THETPATTAPRQ
Mb2108|M.bovis_AF2122/97 G-----------------------------------TTTVAAAHHPHGYL
MAV_1296|M.avium_104 --------------------------------PDINPDGPTTLSAIAD--
MUL_1004|M.ulcerans_Agy99 --------------------------------SDINPEGPTTLTGIAD--
Mvan_3343|M.vanbaalenii_PYR-1 ---------------------------------APPLGLPAVPLGD----
Mflv_3843|M.gilvum_PYR-GCK APGTPGSTLTLTDLLTPPGIARTLQNTASSVMGATPPGTPPVPGGSGSVS
Rv0867c|M.tuberculosis_H37Rv -----------------QVSNIAYTKKLWQAIRAQDVCGNDALDSLAQ--
MSMEG_5700|M.smegmatis_MC2_155 -----------------QGPNMTYLREIWHAIQTQDISGKDALLALTQRP
MLBr_00048|M.leprae_Br4923 GVLSTASGVVIVTSTSVDAARQAAIALDWLRHNGYQDLLSRACVVINHVM
MMAR_5451|M.marinum_M GVLDTASAIVILTNVSIDSARQAAIALDWLRKHGYQDLASRACVAINHVA
TH_3807|M.thermoresistible__bu --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 TATVPPSQPVEPTTAPEPTKQHSTPTHDVPTSEAPAPRATAEPAPAEPPA
Mb2108|M.bovis_AF2122/97 SQPDPDTPALTGDRTARIAPTIDELGPTLVETVRRHDTLPRIAQAVVVAA
MAV_1296|M.avium_104 ---------------------------------------TGSGSIMSTIF
MUL_1004|M.ulcerans_Agy99 ---------------------------------------TGSGSIMSTIF
Mvan_3343|M.vanbaalenii_PYR-1 -AVPGVP------------------------------FLPATLPIPQDLV
Mflv_3843|M.gilvum_PYR-GCK LAVPGTPSPIAPLAATGLSNLVSPPSLTIPSIPGLPVPLPNTVPVPSDLL
Rv0867c|M.tuberculosis_H37Rv ---PYVIG------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 LTTPDVPGG----------------------------AAPNRPVAPPPAP
MLBr_00048|M.leprae_Br4923 PKEPNIASK-----------------------DLVQQFEQQIQPGRVVVL
MMAR_5451|M.marinum_M VGETNVSEQ-----------------------QLVRDFEQQLQPGRVVVL
TH_3807|M.thermoresistible__bu --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 KQAPAERETP---------------------------PSRTAAPEPAAPT
Mb2108|M.bovis_AF2122/97 TRNYGVPDNE--------------TDLLHHKTTEIHQAVLTTYPNHDIAT
MAV_1296|M.avium_104 GQVTTKERQCQFMPTIGSTVVP--------------------
MUL_1004|M.ulcerans_Agy99 GQVTTKERQCQFMPTIGSTVVP--------------------
Mvan_3343|M.vanbaalenii_PYR-1 CEGTAWSAGR--TAPEGDAAALD------APPGQRRDQW---
Mflv_3843|M.gilvum_PYR-GCK CVGTDWSASQGDSAATPPAAEVPRVVTGAAPTGDRRDRWGNR
Rv0867c|M.tuberculosis_H37Rv ------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 GDPALAPAPAPLGAPAPAPAPEPAPVGAPAPVGAPVPPPA--
MLBr_00048|M.leprae_Br4923 PWDKHIAAGTEIRLDRLDPLYRRRILELAAALSDDFERAGRH
MMAR_5451|M.marinum_M PWDRHIAAGTEIHLDQLGPVYRRRVLELAAALSDDFERAGRR
TH_3807|M.thermoresistible__bu ------------------------------------------
MAB_2960|M.abscessus_ATCC_1997 REAPAREAPTREAPSYSTATQAPSAGGGNSGGGSGGGRH---
Mb2108|M.bovis_AF2122/97 VVDWMLLAAINALIAGDQSGANYHLAWAIAAISTRRSR----