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MSGRHRKPTTSNVSVAKIAFTGAVLGGGGIALAGHAAAATDGEWDQVARCESGGNWAINTGNGYYGGVQF AQSTWASHGGGEYAPSAQLASREEQIAVAERVLATQGRGAWPVCGHGLSAATPRDVPAPAALDAPLDAPG INGEPAPLAPPPGDDVPPPADPAPPVELAANDVPAPADLPPAPEDLPPAPEDLAPPAPADLPPAPEDLPP APQDLPPAPEDVAAPAPADLPPAPEDVAPPVELVGNDVPAPVDLPPAPEDLPPAPEDLAPPAPADLPPAP EDLAPPAPADLPPAPEDLAPPAPADLPPAPEDLAPPAPADLPPAPEDLPPAPEDLPPPADADNPPVDVHE ASTVAYTKKLWQAIVGQNISGNDALDALAQPTVFA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4665 | rpfA | - | 100% (385) | resuscitation-promoting factor RpfA |
| M. marinum M | MMAR_3776 | rpfE | 4e-28 | 51.39% (144) | resuscitation-promoting factor RpfE |
| M. marinum M | MMAR_5451 | - | 1e-25 | 31.95% (266) | hypothetical protein MMAR_5451 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0891c | rpfA | 1e-113 | 58.88% (394) | resuscitation-promoting factor RpfA |
| M. gilvum PYR-GCK | Mflv_1703 | - | 1e-105 | 53.72% (430) | transglycosylase domain-containing protein |
| M. tuberculosis H37Rv | Rv0867c | rpfA | 1e-143 | 66.67% (420) | resuscitation-promoting factor RpfA |
| M. leprae Br4923 | MLBr_02151 | - | 3e-64 | 67.78% (180) | hypothetical protein MLBr_02151 |
| M. abscessus ATCC 19977 | MAB_0869c | - | 3e-78 | 45.09% (397) | resuscitation-promoting factor RpfA |
| M. avium 104 | MAV_0996 | - | 3e-75 | 70.14% (211) | resuscitation-promoting factor RpfA |
| M. smegmatis MC2 155 | MSMEG_5700 | - | 1e-113 | 53.30% (439) | secreted protein |
| M. thermoresistible (build 8) | TH_0358 | - | 7e-29 | 51.47% (136) | PROBABLE RESUSCITATION-PROMOTING FACTOR RPFE |
| M. ulcerans Agy99 | MUL_0283 | rpfA | 1e-143 | 90.41% (271) | resuscitation-promoting factor RpfA |
| M. vanbaalenii PYR-1 | Mvan_5049 | - | 1e-105 | 54.00% (413) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1703|M.gilvum_PYR-GCK MSGRHRKPAS--SAKSVAKIAFTG-AVIGGGGIALAGHAGAATDGEWDRV
Mvan_5049|M.vanbaalenii_PYR-1 MSGRHRKPAP--SAVNVAKIAFTG-AVIGGGGLALAGQAGAATDGEWDQV
MSMEG_5700|M.smegmatis_MC2_155 MSGRHRKPTSSSSAKNVAKIAFTG-AVLGGGGLGMAGQAMAATDGEWDQV
MMAR_4665|M.marinum_M MSGRHRKPTT--SNVSVAKIAFTG-AVLGGGGIALAGHAAAATDGEWDQV
MUL_0283|M.ulcerans_Agy99 MSGRHRKPTT--SNVSVAKIAFTG-AVLGGGGIALAGHAAAATDGEWDQV
Mb0891c|M.bovis_AF2122/97 MSGRHRKPTT--SNVSVAKIAFTG-AVLGGGGIAMAAQATAATDGEWDQV
Rv0867c|M.tuberculosis_H37Rv MSGRHRKPTT--SNVSVAKIAFTG-AVLGGGGIAMAAQATAATDGEWDQV
MLBr_02151|M.leprae_Br4923 MSESYRKLTT--SSIIVAKITFTG-AMLDG-SIALAGQASPATDSEWDQV
MAV_0996|M.avium_104 --------------------------MLGGGAIAMAGQAAAATDGEWDQV
MAB_0869c|M.abscessus_ATCC_199 MSGRHSKPSK--ASAKAAKVAVAG-AGLVGGGLMMAATANAATDGEWDQV
TH_0358|M.thermoresistible__bu MN-NIRKALT--SSLKRALLLIAGTAALALVPMVLSTATAQADTVNWDAI
: : :: : * :** :
Mflv_1703|M.gilvum_PYR-GCK ASCESGGNWAINTGNGYHGGLQFSPSTWSGHGGGEFAPAAYLATKEEQIA
Mvan_5049|M.vanbaalenii_PYR-1 ARCESGGNWAINTGNGYHGGLQFSPGTWSGHGGGEYAPAAYLATKEEQIA
MSMEG_5700|M.smegmatis_MC2_155 ARCESGGNWAINTGNGYHGGLQFSPSTWRAHGGTEFAPAAYMATKEEQIA
MMAR_4665|M.marinum_M ARCESGGNWAINTGNGYYGGVQFAQSTWASHGGGEYAPSAQLASREEQIA
MUL_0283|M.ulcerans_Agy99 ARCESGGNWAINTGNGYYGGVQFAQSTWASHGGGEYAPSAQLASREEQIA
Mb0891c|M.bovis_AF2122/97 ARCESGGNWSINTGNGYLGGLQFTQSTWAAHGGGEFAPSAQLASREQQIA
Rv0867c|M.tuberculosis_H37Rv ARCESGGNWSINTGNGYLGGLQFTQSTWAAHGGGEFAPSAQLASREQQIA
MLBr_02151|M.leprae_Br4923 ARCESGGNWSINTGNGYLGGLQFSQGTWASHGGGEYAPSAQLATREQQIA
MAV_0996|M.avium_104 ARCESGGNWGINTGNGYHGGVQFSASTWAAHGGGEYAPSAELATREQQIA
MAB_0869c|M.abscessus_ATCC_199 ARCESGGNWAINTGNGYQGGLQFSPSTWINSGGGQYAPSAHLATKEQQIA
TH_0358|M.thermoresistible__bu AQCESGGNWASDTGNGFYGGLQFKPSTWAAHGG---TGSPARASREEQIR
* *******. :****: **:** .** ** : :. *::*:**
Mflv_1703|M.gilvum_PYR-GCK VAERVLASQGKGAWPTCGKVLSAATPRNVVDEPPA-PAPVDPLGLNGVLP
Mvan_5049|M.vanbaalenii_PYR-1 VAERVLASQGKGAWPSCGGPLSAATPRNVVAEP---PAPVDPVGLNGLLP
MSMEG_5700|M.smegmatis_MC2_155 VAERVLASQGKGAWPTCGRGLSGATPRNVVAEP-E-PAPLDAPGVNGELP
MMAR_4665|M.marinum_M VAERVLATQGRGAWPVCGHGLSAATPRDV-PAPAALDAPLDAPGINGEPA
MUL_0283|M.ulcerans_Agy99 VAERVLATQGRGAWPVCGHGLSAATPRDV-PPPAALDAPLDAPGINGEPA
Mb0891c|M.bovis_AF2122/97 VGERVLATQGRGAWPVCGRGLSNATPREVLPASAAMDAPLDAAAVNGEPA
Rv0867c|M.tuberculosis_H37Rv VGERVLATQGRGAWPVCGRGLSNATPREVLPASAAMDAPLDAAAVNGEPA
MLBr_02151|M.leprae_Br4923 VAERVLATQGSGAWPACGHGLSGPSLQEVLPAGMG------APWINGAPA
MAV_0996|M.avium_104 VAERVLATQGRGAWPVCGGPLSGPTPRDV-PAPAG----LDAPGVNG--V
MAB_0869c|M.abscessus_ATCC_199 VAEKVLAGQGRGAWPVCGRGLSGSTPRTAPAANITPAAHHEEQAAAEPAP
TH_0358|M.thermoresistible__bu VAERVLASQGLKAWPKCG---AHGTRPAVFRTP-----------------
*.*:*** ** *** ** : : .
Mflv_1703|M.gilvum_PYR-GCK PPPAPLDPFAPPPP------------------------------------
Mvan_5049|M.vanbaalenii_PYR-1 PP--PVDPFAPPP-------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 PP-APVDMLAAPM-------------------------------------
MMAR_4665|M.marinum_M PLAPP---------------------------------------------
MUL_0283|M.ulcerans_Agy99 PLAPP---------------------------------------------
Mb0891c|M.bovis_AF2122/97 PLAPP---------------------------------------------
Rv0867c|M.tuberculosis_H37Rv PLAPPPADPAPPVELAANDLPAPLGEPLPAAPADPAPPADLAPPAPADVA
MLBr_02151|M.leprae_Br4923 PLAPPP--------------------------------------------
MAV_0996|M.avium_104 PQAPP---------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 APEPPAEG------------------------------------------
TH_0358|M.thermoresistible__bu --------------------------------------------------
Mflv_1703|M.gilvum_PYR-GCK ----------------------PPAPAPFDALAAPAPAPLPPAPETLPPA
Mvan_5049|M.vanbaalenii_PYR-1 ------------------------APAPVDALAAPAP--LPPAPEALP--
MSMEG_5700|M.smegmatis_MC2_155 -------------------------PAPEG--LPPAPEALPPAPEALP--
MMAR_4665|M.marinum_M -----------------------------------PGDDVPP--------
MUL_0283|M.ulcerans_Agy99 -----------------------------------PGDDVPP--------
Mb0891c|M.bovis_AF2122/97 -----------------------------------PADLAPPAPADLAP-
Rv0867c|M.tuberculosis_H37Rv PPVELAVNDLPAPLGEPLPAAPADPAPPADLAPPAPADLAPPAPADLAP-
MLBr_02151|M.leprae_Br4923 -----------------------------------PAEPAPPQP------
MAV_0996|M.avium_104 ------------------------------------ADAPPP--------
MAB_0869c|M.abscessus_ATCC_199 -----------------------------DEQFVAEAPEAPAIDEAPAP-
TH_0358|M.thermoresistible__bu --------------------------------------------------
Mflv_1703|M.gilvum_PYR-GCK PVEQLAAPVPLPAPAPEAVPVDAMA-APAPLPPAPEALPPAPLDAPAPAQ
Mvan_5049|M.vanbaalenii_PYR-1 -----------PAPAP-AAPFDAMS-APAPLPPAPEALP------PAPAP
MSMEG_5700|M.smegmatis_MC2_155 -----------PAPEAPAPAPEALPPAPEALPPAPEALPPAP-EAPAPAP
MMAR_4665|M.marinum_M -------------PADPAPPVELAA----NDVPAPADLPPAPEDLPPAPE
MUL_0283|M.ulcerans_Agy99 -------------PADPAPPVELAA----NDVPAPADLPPAPEDLPPAPE
Mb0891c|M.bovis_AF2122/97 -----------PAPADLAPPVELAV----NDLPAPLGEP-----LPAAPA
Rv0867c|M.tuberculosis_H37Rv -----------PAPADLAPPVELAV----NDLPAPLGEP-----LPAAPA
MLBr_02151|M.leprae_Br4923 -------------PADNFPPTP-------GDVPSPLARP-----------
MAV_0996|M.avium_104 ------------------APVQLAS----FDRPAPPDAP---------AP
MAB_0869c|M.abscessus_ATCC_199 ----------EEAPAPEAQDVDFQS-GPAPEEPAPAPEPAPVDEAQAPAP
TH_0358|M.thermoresistible__bu ------------------------------GAPAAGGVP-------ASTP
*:. *
Mflv_1703|M.gilvum_PYR-GCK TVAFDAVAAPA----PLP-APEALPPAPLPAPAPEAVP------FDALSA
Mvan_5049|M.vanbaalenii_PYR-1 AAPFDAMSAPA----PLPPAPEALP----PAPVVDAAN------IAPLDA
MSMEG_5700|M.smegmatis_MC2_155 EALPPAPEAPAPVAEALPPAPEALPPAPEAPPAPEALPPAPEAQIVDASL
MMAR_4665|M.marinum_M DLAPPAPADLP-------PAPEDLPP------------------------
MUL_0283|M.ulcerans_Agy99 DLAPPAPADLP-------PAPEDLPP------------------------
Mb0891c|M.bovis_AF2122/97 ELAP--PADLA-------PASADLAPP-----------------------
Rv0867c|M.tuberculosis_H37Rv ELAP--PADLA-------PASADLAPP-----------------------
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
MAV_0996|M.avium_104 DAPPPAPADLP-------PAPADLPPA-----------------------
MAB_0869c|M.abscessus_ATCC_199 ELIAAPAPEAP--VVDEAPAPEEAPAPEAPAADDQVLP------YELQSG
TH_0358|M.thermoresistible__bu TATTGCGAIRP---------------------------------------
Mflv_1703|M.gilvum_PYR-GCK PAPVEPIVAPIPVDAPP--SAVVTA-------------VNWDTAPAPAPG
Mvan_5049|M.vanbaalenii_PYR-1 PLP-----PPAPVDAPPAQSAIIAA-------------ANWDTAPVPG-E
MSMEG_5700|M.smegmatis_MC2_155 QVPADVPPAPPVEPAPPAPVDAVAAPE----------NQNWDQAPAPA-D
MMAR_4665|M.marinum_M -APQDLPP-APEDVAAPAPADLPPAPEDVAPPVELVGNDVPAPVDLPPAP
MUL_0283|M.ulcerans_Agy99 -APQDLPP-APEDVAAPAPADLP---------------------------
Mb0891c|M.bovis_AF2122/97 -APADLAPPAPAELAPPAPADLAP--------------------------
Rv0867c|M.tuberculosis_H37Rv -APADLAPPAPAELAPPAPADLAP--------------------------
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
MAV_0996|M.avium_104 -PPADATPPAPPADAPAPDGDFHG--------------------------
MAB_0869c|M.abscessus_ATCC_199 PAPAEPAPAPEPAPAPAAAPEIPLPAG-----------------------
TH_0358|M.thermoresistible__bu --------------------------------------------------
Mflv_1703|M.gilvum_PYR-GCK DPQMWSLGLDAPLQPAPVTP-----PLPAPAP---ETVAAPAPVVGVPAG
Mvan_5049|M.vanbaalenii_PYR-1 HPQLWSLGVDAPLQPAPVLPP---APAPAPAP---AAVAAPAPDPLAPLG
MSMEG_5700|M.smegmatis_MC2_155 QPQTWALHVGGPLPLDPVLPAPAPAPAPAPAPGAPAAVAAPAPDPLAPAP
MMAR_4665|M.marinum_M EDLPPAPEDLAPPAPADLPPAPEDLAPPAPADLPPAPEDLAPPAPADLPP
MUL_0283|M.ulcerans_Agy99 ---------------------------PAPADLPPAPEDLAP--------
Mb0891c|M.bovis_AF2122/97 ---------------------------PAAVNEQTAPGDQPATAPGGPVG
Rv0867c|M.tuberculosis_H37Rv ---------------------------PAAVNEQTAPGDQPATAPGGPVG
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
MAV_0996|M.avium_104 ----------------------------------FVPAGMP---------
MAB_0869c|M.abscessus_ATCC_199 --------------------------VPDAADIGFAAGKAAFDAGPVASN
TH_0358|M.thermoresistible__bu --------------------------------------------------
Mflv_1703|M.gilvum_PYR-GCK QAG-PVPA-------------APAEVPHLVSPDNPPPGTTVTP-QGPQQS
Mvan_5049|M.vanbaalenii_PYR-1 AVEVPAPAYDIANQAISGELPVPSEVPHLASPDNLPPGTAMAP-QGPRQS
MSMEG_5700|M.smegmatis_MC2_155 NADVAPTP--------------PEGVPHLASPENLPPGTTETPDQIPGQG
MMAR_4665|M.marinum_M APEDLAPPAPAD-------LPPAPEDLPPAPEDLPPPADADNPPVDVHEA
MUL_0283|M.ulcerans_Agy99 -------------------------------------------PVDVHEA
Mb0891c|M.bovis_AF2122/97 LATDLELPEPD-----------------PQPADAPPPGDVTEAPAETPQV
Rv0867c|M.tuberculosis_H37Rv LATDLELPEPD-----------------PQPADAPPPGDVTEAPAETPQV
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
MAV_0996|M.avium_104 -----------------------------------------------DHV
MAB_0869c|M.abscessus_ATCC_199 GIPTSPEAVAG-------------VVRHLPDPNNLPPG---TTDVAPGDS
TH_0358|M.thermoresistible__bu -----------------------------------------------GAV
Mflv_1703|M.gilvum_PYR-GCK PNVTYLKEIWHAIQTQEISGSDALLALTQRPLTANG--GGPAP---MAPV
Mvan_5049|M.vanbaalenii_PYR-1 PNVTYLKEIWHAIQTQEISGADALLALTQRPLTTPDTPGGTPP---IAP-
MSMEG_5700|M.smegmatis_MC2_155 PNMTYLREIWHAIQTQDISGKDALLALTQRPLTTPDVPGGAAPNRPVAPP
MMAR_4665|M.marinum_M STVAYTKKLWQAIVGQNISGNDALDALAQPTVFA----------------
MUL_0283|M.ulcerans_Agy99 STVAYTKKLWQAIVGQNISGNDALDALAQPAVFA----------------
Mb0891c|M.bovis_AF2122/97 SNIAYTKKLWQAIRAQDVCGNDALDSLAQPYVIG----------------
Rv0867c|M.tuberculosis_H37Rv SNIAYTKKLWQAIRAQDVCGNDALDSLAQPYVIG----------------
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
MAV_0996|M.avium_104 SEAGYTQRLWEAIRAQDVQGNDALDALVQPAPSA----------------
MAB_0869c|M.abscessus_ATCC_199 RGVSYLKDIVFAMQTQDVKASDAILALAQR--------------------
TH_0358|M.thermoresistible__bu LGLVDLRQVCAAFLTPLGVG------------------------------
Mflv_1703|M.gilvum_PYR-GCK ---GAPAPAPEAPVQGAAAPLPAPA-------VPAPAPVLPPA
Mvan_5049|M.vanbaalenii_PYR-1 ---GAPG-APVAPLAG-PAPAPAP--------VPAPAPVLPPA
MSMEG_5700|M.smegmatis_MC2_155 PAPGDPALAPAPAPLGAPAPAPAPEPAPVGAPAPVGAPVPPPA
MMAR_4665|M.marinum_M -------------------------------------------
MUL_0283|M.ulcerans_Agy99 -------------------------------------------
Mb0891c|M.bovis_AF2122/97 -------------------------------------------
Rv0867c|M.tuberculosis_H37Rv -------------------------------------------
MLBr_02151|M.leprae_Br4923 -------------------------------------------
MAV_0996|M.avium_104 -------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 -------------------------------------------
TH_0358|M.thermoresistible__bu -------------------------------------------