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KFGFRARIASVAGAAAFATLIAAAPSASADPAAPAPAPLPVPGPAVPDSAPLPAPVAAPMASPVPAPLAA PIAGPASVQSLAAGPVEPVAEGVPHLASPENLPPGTSTTPTQQSRLGYLRDLWHAMQTQEVSGSNALLLL TQRPLSSSPSAGMPAGPQPVAPPAPAPVAPPVVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3011 | - | - | 100% (175) | hypothetical protein Mvan_3011 |
| M. vanbaalenii PYR-1 | Mvan_5049 | - | 2e-28 | 48.34% (151) | FHA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3343 | - | 7e-11 | 33.33% (171) | FHA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0891c | rpfA | 4e-11 | 35.71% (140) | resuscitation-promoting factor RpfA |
| M. gilvum PYR-GCK | Mflv_3289 | - | 8e-48 | 62.35% (170) | hypothetical protein Mflv_3289 |
| M. tuberculosis H37Rv | Rv0867c | rpfA | 4e-11 | 35.71% (140) | resuscitation-promoting factor RpfA |
| M. leprae Br4923 | MLBr_01828 | PPE | 7e-07 | 26.26% (198) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_0869c | - | 9e-19 | 46.49% (114) | resuscitation-promoting factor RpfA |
| M. marinum M | MMAR_4294 | - | 1e-11 | 36.14% (166) | hypothetical protein MMAR_4294 |
| M. avium 104 | MAV_1296 | - | 6e-11 | 32.62% (187) | hypothetical protein MAV_1296 |
| M. smegmatis MC2 155 | MSMEG_5700 | - | 1e-30 | 48.52% (169) | secreted protein |
| M. thermoresistible (build 8) | TH_3807 | - | 1e-08 | 32.50% (200) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1004 | - | 1e-12 | 44.79% (96) | hypothetical protein MUL_1004 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3011|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3289|M.gilvum_PYR-GCK --------------------------------------------------
Mb0891c|M.bovis_AF2122/97 --------------------------------------------------
Rv0867c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_4294|M.marinum_M --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MAV_1296|M.avium_104 --------------------------------------------------
TH_3807|M.thermoresistible__bu --------------------------------------------------
MLBr_01828|M.leprae_Br4923 MSAPIWMASPPEVHSALLSRGPGSGPLLVAAEAWRSLSSVYAEMADELVA
Mvan_3011|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3289|M.gilvum_PYR-GCK --------------------------------------------------
Mb0891c|M.bovis_AF2122/97 ------------------------MSGRHRKPTTSN--VSVAKIAFTGAV
Rv0867c|M.tuberculosis_H37Rv ------------------------MSGRHRKPTTSN--VSVAKIAFTGAV
MSMEG_5700|M.smegmatis_MC2_155 ------------------------MSGRHRKPTSSSSAKNVAKIAFTGAV
MAB_0869c|M.abscessus_ATCC_199 ------------------------MSGRHSKPSKAS--AKAAKVAVAGAG
MMAR_4294|M.marinum_M -------------------------MASTWSLSKGLAAVVVTSAAAFGLC
MUL_1004|M.ulcerans_Agy99 -------------------------MASTWSLSKGLAAVVVTSAAAFGLC
MAV_1296|M.avium_104 -------------------------MATTWILSKGLAAVVTASVAALGLC
TH_3807|M.thermoresistible__bu --------------------------------------MRATRKLITSSV
MLBr_01828|M.leprae_Br4923 LLVVVPVSSWDGSAAEAYVIAYLPYLGWLRQASVDSAVMAAHYETMATAY
Mvan_3011|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3289|M.gilvum_PYR-GCK --------------------------------------------------
Mb0891c|M.bovis_AF2122/97 LGGGGIAMAAQATAATDGEWDQVARCESGGNWSINTGNGYLGGLQFTQST
Rv0867c|M.tuberculosis_H37Rv LGGGGIAMAAQATAATDGEWDQVARCESGGNWSINTGNGYLGGLQFTQST
MSMEG_5700|M.smegmatis_MC2_155 LGGGGLGMAGQAMAATDGEWDQVARCESGGNWAINTGNGYHGGLQFSPST
MAB_0869c|M.abscessus_ATCC_199 LVGGGLMMAATANAATDGEWDQVARCESGGNWAINTGNGYQGGLQFSPST
MMAR_4294|M.marinum_M PGAAADP-AAPQPNP----NPQLPGLPALAQLSPIIQQAAGNPEQATQLL
MUL_1004|M.ulcerans_Agy99 PAAAADP-AAPQPNP----NPQLPGLPALAQLSPIIQQAAGNPEQATQLL
MAV_1296|M.avium_104 PGAAADPAAAPQPAPPPNAAPQLPGLPALSQLSPLIQQAATDPQQATQLL
TH_3807|M.thermoresistible__bu IAAGGAVAVALTCSATAAAQPAPAPAPSPG-----------------VPF
MLBr_01828|M.leprae_Br4923 ITTLAMMPTLAELAANRTAHTVLVTTNFFGINTIPIARNEIDYVRMWVEA
Mvan_3011|M.vanbaalenii_PYR-1 ------MKFGFRARIAS-----------VAG-------------------
Mflv_3289|M.gilvum_PYR-GCK ------MKFGFRAKTAS-----------IIG-------------------
Mb0891c|M.bovis_AF2122/97 WAAHGGGEFAPSAQLASREQQIAVGERVLATQGRGAWPVCGRGLSNATPR
Rv0867c|M.tuberculosis_H37Rv WAAHGGGEFAPSAQLASREQQIAVGERVLATQGRGAWPVCGRGLSNATPR
MSMEG_5700|M.smegmatis_MC2_155 WRAHGGTEFAPAAYMATKEEQIAVAERVLASQGKGAWPTCGRGLSGATPR
MAB_0869c|M.abscessus_ATCC_199 WINSGGGQYAPSAHLATKEQQIAVAEKVLAGQGRGAWPVCGRGLSGSTPR
MMAR_4294|M.marinum_M MAAAQAFAHNPAAPTESRNVASSVNQFVQEPVNPAPGSPPLGVPAPAAAP
MUL_1004|M.ulcerans_Agy99 MAAAQAFAHNPAAPTESRNVASSVNQFVQEPVNPAPGSPPLGVPAPAAAP
MAV_1296|M.avium_104 MAAAQAFSHNPTAPTESKNVAAAVNQFVAEPGSPVPNG------------
TH_3807|M.thermoresistible__bu MDQLATAAANAPAILQS---------------------------------
MLBr_01828|M.leprae_Br4923 AIAMGTYQEVSTVVVDSAPEAIAAPQIMASDALEASSDQPSPTAPSQSPQ
. :
Mvan_3011|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3289|M.gilvum_PYR-GCK --------------------------------------------------
Mb0891c|M.bovis_AF2122/97 EVLPASAAMDAPLDAAAVNGEPAPLAPP----------------------
Rv0867c|M.tuberculosis_H37Rv EVLPASAAMDAPLDAAAVNGEPAPLAPPPADPAPPVELAANDLPAPLGEP
MSMEG_5700|M.smegmatis_MC2_155 NVVAE--PEPAPLDAPGVNGELPPPAPVDMLAAP----------MPAPEG
MAB_0869c|M.abscessus_ATCC_199 TAPAANITPAAHHEEQAAAEPAPAPEPPAEGDEQ---------FVAEAPE
MMAR_4294|M.marinum_M VEVAPPASAPVPHVPAPGAEPGTLAHLPAG--------------------
MUL_1004|M.ulcerans_Agy99 VEVAPPASAPVPHVPAPGAEPGTLAHLPAG--------------------
MAV_1296|M.avium_104 --VTPPDGAPVQHVPATGIEPGLQAHLPTG--------------------
TH_3807|M.thermoresistible__bu --------------------------------------------------
MLBr_01828|M.leprae_Br4923 VQNWLQWLQKIGYTDFYNTLVQPLITSLTNHPFFQGMFSGFDPWLPSLGN
Mvan_3011|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3289|M.gilvum_PYR-GCK --------------------------------------------------
Mb0891c|M.bovis_AF2122/97 --------------------------------------------------
Rv0867c|M.tuberculosis_H37Rv LPAAPADPAPPADLAPPAPADVAP---PVELAVNDLPAPLGEPLPAAPAD
MSMEG_5700|M.smegmatis_MC2_155 LPPAPEALPPAPEALPPAP------------------------------E
MAB_0869c|M.abscessus_ATCC_199 APAIDEAPAPEEAPAPEAQD----------------------------VD
MMAR_4294|M.marinum_M --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MAV_1296|M.avium_104 --------------------------------------------------
TH_3807|M.thermoresistible__bu --------------------------------------------------
MLBr_01828|M.leprae_Br4923 PLSFLSPFNIAFALGTPMDIGSYVGYLSQTFAFIGADLAAAFASGNPVTI
Mvan_3011|M.vanbaalenii_PYR-1 ---------------------AAAFATLIAAAPSASADPAAPAPAPLPVP
Mflv_3289|M.gilvum_PYR-GCK ---------------------AAAAATLMAAAPSALAEPTGPG---LPEP
Mb0891c|M.bovis_AF2122/97 -----------PADLAPPAPADLAPPAPADLAPPVELAVN-DLPAPLGEP
Rv0867c|M.tuberculosis_H37Rv PAPPADLAPPAPADLAPPAPADLAPPAPADLAPPVELAVN-DLPAPLGEP
MSMEG_5700|M.smegmatis_MC2_155 APAPAPEALPPAPEALPPAPEALPPAPEAPAPAPEALPPAPEAPAPVAEA
MAB_0869c|M.abscessus_ATCC_199 FQSGPAPEEPAPAPEPAPVDEAQAPAPELIAAPAPEAPVVDEAPAPEEAP
MMAR_4294|M.marinum_M ---IDPAHAAGPAPVAAPAGAPPASAPAPAAAAPASAPGTAPAPAAAPGP
MUL_1004|M.ulcerans_Agy99 ---IDPAHAAGPAPVAAPAGAPPASAPAPAAAAPASAPGTAPAPAAAPGP
MAV_1296|M.avium_104 ---IDPAHAAGPAPAAA----------APSAPAPAATPPSAPAPAAAPAP
TH_3807|M.thermoresistible__bu --------------------AAAALGGTNTMPSAPVVAPPPAATAQITVP
MLBr_01828|M.leprae_Br4923 GFTLLFTTIEAIGTIITDTIALVKTMIEQSFVLLPMILPLLTAPLAVATA
.
Mvan_3011|M.vanbaalenii_PYR-1 GPAVPDS-----------APLPAPVAAP-----------------MASPV
Mflv_3289|M.gilvum_PYR-GCK APALLSAP----------TPPPAPDAQP-----------------TVPLT
Mb0891c|M.bovis_AF2122/97 LPAAPAE----LAPPADLAPASADLAPP--------------APADLAPP
Rv0867c|M.tuberculosis_H37Rv LPAAPAE----LAPPADLAPASADLAPP--------------APADLAPP
MSMEG_5700|M.smegmatis_MC2_155 LPPAPEA----LPPAPEAPPAPEALPPAPEAQIVD---ASLQVPADVPPA
MAB_0869c|M.abscessus_ATCC_199 APEAPAADDQVLPYELQSGPAPAEPAPA----------------PEPAPA
MMAR_4294|M.marinum_M APAAPAP----APAAAAPAPAPAPAAPPAAPVAA----PAPVPAPAPAAA
MUL_1004|M.ulcerans_Agy99 APAAPAP----APAAAAPAPAPAPAAPPAAPVAAPVAAPAPVPAPAPAAA
MAV_1296|M.avium_104 GPVQPAT----VPAAAPVPPPPAPAA-------------------AAPAT
TH_3807|M.thermoresistible__bu QPALPAT----------VAPATAPIIKQ---------------PGTVTPT
MLBr_01828|M.leprae_Br4923 GAAGSFAGLSELAGLVGVAPPGLPSAPPVAAVAPVVP-PSMPTLASIPTP
. * .
Mvan_3011|M.vanbaalenii_PYR-1 PAPLAAPIAGPASVQSLAAG---------------------PVEPVAEG-
Mflv_3289|M.gilvum_PYR-GCK PPAPAAPVA-AASGDPAAVP---------------------PAAPAADAG
Mb0891c|M.bovis_AF2122/97 APAELAPPAPADLAPPAAVN---EQTAPGDQP---ATAPGGPVGLATDLE
Rv0867c|M.tuberculosis_H37Rv APAELAPPAPADLAPPAAVN---EQTAPGDQP---ATAPGGPVGLATDLE
MSMEG_5700|M.smegmatis_MC2_155 PPVEPAPPAPVDAVAAPENQNWDQAPAPADQPQTWALHVGGPLPLDPVLP
MAB_0869c|M.abscessus_ATCC_199 PAAAPEIPLPAGVPDAADIGFAAGKAAFDAGP---VASNGIPTSPEAVAG
MMAR_4294|M.marinum_M PAPEAAAPAPAPAPAPAAAPGFGPDAPPTQDFMYPSIGTNCLADGSNIIA
MUL_1004|M.ulcerans_Agy99 PAPEAAAPAPAPAPAPAAAPGFGPDAPPTQDFMYPSIGTNCLADGSNIIA
MAV_1296|M.avium_104 PG------APDAAPAPAAAPGFGADAPPTQDFMYPSIGTNCLADGSSAIA
TH_3807|M.thermoresistible__bu APGVPLPTAEATLPNVAGTP------------------------VPQQVS
MLBr_01828|M.leprae_Br4923 TPMPAPAASTAPVVTPPGPPPVTAPPSVTGAGVESFGYLVGRLPSTARGV
.
Mvan_3011|M.vanbaalenii_PYR-1 VPHLAS-PENLP--------------------------------------
Mflv_3289|M.gilvum_PYR-GCK VPHLAS-PENLP--------------------------------------
Mb0891c|M.bovis_AF2122/97 LPEPDPQPADAP--------------------------------------
Rv0867c|M.tuberculosis_H37Rv LPEPDPQPADAP--------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 APAPAPAPAPAPGAPAAVAAPAPDPLAPAPNADVAPTPPEGVPHLASPEN
MAB_0869c|M.abscessus_ATCC_199 VVRHLPDPNNLP--------------------------------------
MMAR_4294|M.marinum_M TALSVAGPATIPTP------------------------------------
MUL_1004|M.ulcerans_Agy99 TALSVAGPATIPTP------------------------------------
MAV_1296|M.avium_104 TALSVAGPAKIPAP------------------------------------
TH_3807|M.thermoresistible__bu LPADVS--------------------------------------------
MLBr_01828|M.leprae_Br4923 VGTSVRQQSSAPDR-----------------------------------I
Mvan_3011|M.vanbaalenii_PYR-1 --PGTSTTPTQQSR-----LGYLRDLWHAMQ-----TQEVS-GSNALLLL
Mflv_3289|M.gilvum_PYR-GCK --PGTSATPTQQGR-----LGYFRELWHAMR-----TQEVS-GSDALLLL
Mb0891c|M.bovis_AF2122/97 -PPGDVTEAPAETP-QVSNIAYTKKLWQAIR-----AQDVC-GNDALDSL
Rv0867c|M.tuberculosis_H37Rv -PPGDVTEAPAETP-QVSNIAYTKKLWQAIR-----AQDVC-GNDALDSL
MSMEG_5700|M.smegmatis_MC2_155 LPPG-TTETPDQIPGQGPNMTYLREIWHAIQ-----TQDIS-GKDALLAL
MAB_0869c|M.abscessus_ATCC_199 --PGTTDVAPGDSR----GVSYLKDIVFAMQ-----TQDVK-ASDAILAL
MMAR_4294|M.marinum_M -GPGPGQTAYVFTAVGTPGPAEVQRLPLNVT-----WVNLTTGKSGSVTL
MUL_1004|M.ulcerans_Agy99 -GPGPGQTAYVFTAVGTPGPAEVQRLPLNVT-----WVNLTTGKSGSVTL
MAV_1296|M.avium_104 -GPGPGQTAYVFTAVGTPGPAEEQKLPLNVT-----WVNLTTGKSGTVAL
TH_3807|M.thermoresistible__bu ------ALLPAAGS-------QLANLMPAVP-----NEPGAPAPATPPML
MLBr_01828|M.leprae_Br4923 EAPDAAATPQEQARSRWRRRAKVTPFDSSGSPNPKAAPTASDQGAGTLGL
: *
Mvan_3011|M.vanbaalenii_PYR-1 TQRPLSSSPSAG------------------MPAGPQPVAPPAPAPVAPPV
Mflv_3289|M.gilvum_PYR-GCK TQRPMSSGPQQA------------------MSP-----VPPAPAPAP---
Mb0891c|M.bovis_AF2122/97 AQ-----PYVIG--------------------------------------
Rv0867c|M.tuberculosis_H37Rv AQ-----PYVIG--------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 TQRPLTTPDVPGGAAPNRPVAPPPAPGDPALAPAPAPLGAPAPAPAPEPA
MAB_0869c|M.abscessus_ATCC_199 AQR-----------------------------------------------
MMAR_4294|M.marinum_M KPRSDINPEGPTTLTGIADTGSGSIMSTIFGQVTTKERQCQFMPTIGSTV
MUL_1004|M.ulcerans_Agy99 KPRSDINPEGPTTLTGIADTGSGSIMSTIFGQVTTKERQCQFMPTIGSTV
MAV_1296|M.avium_104 KPRPDINPDGPTTLSAIADTGSGSIMSTIFGQVTTKERQCQFMPTIGSTV
TH_3807|M.thermoresistible__bu PSGLFPTSALP---------------------------------------
MLBr_01828|M.leprae_Br4923 AGTARQASSGPATGLVTLSNGTFSDSPRAPMLPRTWGADPTFCYNAADIG
Mvan_3011|M.vanbaalenii_PYR-1 VP--------------
Mflv_3289|M.gilvum_PYR-GCK ----------------
Mb0891c|M.bovis_AF2122/97 ----------------
Rv0867c|M.tuberculosis_H37Rv ----------------
MSMEG_5700|M.smegmatis_MC2_155 PVGAPAPVGAPVPPPA
MAB_0869c|M.abscessus_ATCC_199 ----------------
MMAR_4294|M.marinum_M VP--------------
MUL_1004|M.ulcerans_Agy99 VP--------------
MAV_1296|M.avium_104 VP--------------
TH_3807|M.thermoresistible__bu ----------------
MLBr_01828|M.leprae_Br4923 PAGGWDDE--------