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MSGRHRKPTTSNVSVAKIAFTGAVLGGGGIALAGHAAAATDGEWDQVARCESGGNWAINTGNGYYGGVQF AQSTWASHGGGEYAPSAQLASREEQIAVAERVLATQGRGAWPVCGHGLSAATPRDVPPPAALDAPLDAPG INGEPAPLAPPPGDDVPPPADPAPPVELAANDVPAPADLPPAPEDLPPAPEDLAPPAPADLPPAPEDLPP APQDLPPAPEDVAAPAPADLPPAPADLPPAPEDLAPPVDVHEASTVAYTKKLWQAIVGQNISGNDALDAL AQPAVFA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0283 | rpfA | - | 100% (287) | resuscitation-promoting factor RpfA |
| M. ulcerans Agy99 | MUL_4651 | rpfB | 6e-26 | 70.42% (71) | resuscitation-promoting factor RpfB |
| M. ulcerans Agy99 | MUL_3723 | rpfE | 2e-23 | 68.06% (72) | resuscitation-promoting factor RpfE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0891c | rpfA | 1e-113 | 66.46% (325) | resuscitation-promoting factor RpfA |
| M. gilvum PYR-GCK | Mflv_1703 | - | 2e-85 | 55.09% (334) | transglycosylase domain-containing protein |
| M. tuberculosis H37Rv | Rv0867c | rpfA | 1e-111 | 56.65% (406) | resuscitation-promoting factor RpfA |
| M. leprae Br4923 | MLBr_02151 | - | 1e-64 | 67.78% (180) | hypothetical protein MLBr_02151 |
| M. abscessus ATCC 19977 | MAB_0869c | - | 8e-67 | 51.79% (280) | resuscitation-promoting factor RpfA |
| M. marinum M | MMAR_4665 | rpfA | 1e-143 | 90.41% (271) | resuscitation-promoting factor RpfA |
| M. avium 104 | MAV_0996 | - | 6e-84 | 63.26% (264) | resuscitation-promoting factor RpfA |
| M. smegmatis MC2 155 | MSMEG_5700 | - | 8e-89 | 64.77% (264) | secreted protein |
| M. thermoresistible (build 8) | TH_0358 | - | 2e-28 | 50.74% (136) | PROBABLE RESUSCITATION-PROMOTING FACTOR RPFE |
| M. vanbaalenii PYR-1 | Mvan_5049 | - | 2e-87 | 66.02% (259) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1703|M.gilvum_PYR-GCK MSGRHRKPAS--SAKSVAKIAFTG-AVIGGGGIALAGHAGAATDGEWDRV
Mvan_5049|M.vanbaalenii_PYR-1 MSGRHRKPAP--SAVNVAKIAFTG-AVIGGGGLALAGQAGAATDGEWDQV
MSMEG_5700|M.smegmatis_MC2_155 MSGRHRKPTSSSSAKNVAKIAFTG-AVLGGGGLGMAGQAMAATDGEWDQV
MUL_0283|M.ulcerans_Agy99 MSGRHRKPTT--SNVSVAKIAFTG-AVLGGGGIALAGHAAAATDGEWDQV
MMAR_4665|M.marinum_M MSGRHRKPTT--SNVSVAKIAFTG-AVLGGGGIALAGHAAAATDGEWDQV
Mb0891c|M.bovis_AF2122/97 MSGRHRKPTT--SNVSVAKIAFTG-AVLGGGGIAMAAQATAATDGEWDQV
Rv0867c|M.tuberculosis_H37Rv MSGRHRKPTT--SNVSVAKIAFTG-AVLGGGGIAMAAQATAATDGEWDQV
MLBr_02151|M.leprae_Br4923 MSESYRKLTT--SSIIVAKITFTG-AMLDG-SIALAGQASPATDSEWDQV
MAV_0996|M.avium_104 --------------------------MLGGGAIAMAGQAAAATDGEWDQV
MAB_0869c|M.abscessus_ATCC_199 MSGRHSKPSK--ASAKAAKVAVAG-AGLVGGGLMMAATANAATDGEWDQV
TH_0358|M.thermoresistible__bu MN-NIRKALT--SSLKRALLLIAGTAALALVPMVLSTATAQADTVNWDAI
: : :: : * :** :
Mflv_1703|M.gilvum_PYR-GCK ASCESGGNWAINTGNGYHGGLQFSPSTWSGHGGGEFAPAAYLATKEEQIA
Mvan_5049|M.vanbaalenii_PYR-1 ARCESGGNWAINTGNGYHGGLQFSPGTWSGHGGGEYAPAAYLATKEEQIA
MSMEG_5700|M.smegmatis_MC2_155 ARCESGGNWAINTGNGYHGGLQFSPSTWRAHGGTEFAPAAYMATKEEQIA
MUL_0283|M.ulcerans_Agy99 ARCESGGNWAINTGNGYYGGVQFAQSTWASHGGGEYAPSAQLASREEQIA
MMAR_4665|M.marinum_M ARCESGGNWAINTGNGYYGGVQFAQSTWASHGGGEYAPSAQLASREEQIA
Mb0891c|M.bovis_AF2122/97 ARCESGGNWSINTGNGYLGGLQFTQSTWAAHGGGEFAPSAQLASREQQIA
Rv0867c|M.tuberculosis_H37Rv ARCESGGNWSINTGNGYLGGLQFTQSTWAAHGGGEFAPSAQLASREQQIA
MLBr_02151|M.leprae_Br4923 ARCESGGNWSINTGNGYLGGLQFSQGTWASHGGGEYAPSAQLATREQQIA
MAV_0996|M.avium_104 ARCESGGNWGINTGNGYHGGVQFSASTWAAHGGGEYAPSAELATREQQIA
MAB_0869c|M.abscessus_ATCC_199 ARCESGGNWAINTGNGYQGGLQFSPSTWINSGGGQYAPSAHLATKEQQIA
TH_0358|M.thermoresistible__bu AQCESGGNWASDTGNGFYGGLQFKPSTWAAHGG---TGSPARASREEQIR
* *******. :****: **:** .** ** : :. *::*:**
Mflv_1703|M.gilvum_PYR-GCK VAERVLASQGKGAWPTCGKVLSAATPRNVVDEPPA-PAPVDPLGLNGVLP
Mvan_5049|M.vanbaalenii_PYR-1 VAERVLASQGKGAWPSCGGPLSAATPRNVVAEP---PAPVDPVGLNGLLP
MSMEG_5700|M.smegmatis_MC2_155 VAERVLASQGKGAWPTCGRGLSGATPRNVVAEP-E-PAPLDAPGVNGELP
MUL_0283|M.ulcerans_Agy99 VAERVLATQGRGAWPVCGHGLSAATPRDV-PPPAALDAPLDAPGINGEPA
MMAR_4665|M.marinum_M VAERVLATQGRGAWPVCGHGLSAATPRDV-PAPAALDAPLDAPGINGEPA
Mb0891c|M.bovis_AF2122/97 VGERVLATQGRGAWPVCGRGLSNATPREVLPASAAMDAPLDAAAVNGEPA
Rv0867c|M.tuberculosis_H37Rv VGERVLATQGRGAWPVCGRGLSNATPREVLPASAAMDAPLDAAAVNGEPA
MLBr_02151|M.leprae_Br4923 VAERVLATQGSGAWPACGHGLSGPSLQEVLPAGMG------APWINGAPA
MAV_0996|M.avium_104 VAERVLATQGRGAWPVCGGPLSGPTPRDV-PAPAG----LDAPGVNG--V
MAB_0869c|M.abscessus_ATCC_199 VAEKVLAGQGRGAWPVCGRGLSGSTPRTAPAANITPAAHHEEQAAAEPAP
TH_0358|M.thermoresistible__bu VAERVLASQGLKAWPKCG---AHGTRPAVFRTP-------GAPAAGGVPA
*.*:*** ** *** ** : : .
Mflv_1703|M.gilvum_PYR-GCK PPPAPLDPFAPPPP------------------------------------
Mvan_5049|M.vanbaalenii_PYR-1 PP--PVDPFAPPP-------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 PP-APVDMLAAPM-------------------------------------
MUL_0283|M.ulcerans_Agy99 PLAPPPGDDVPP-------------------PADPAP-------------
MMAR_4665|M.marinum_M PLAPPPGDDVPP-------------------PADPAP-------------
Mb0891c|M.bovis_AF2122/97 PLAPP---------------------------------------------
Rv0867c|M.tuberculosis_H37Rv PLAPPPADPAPPVELAANDLPAPLGEPLPAAPADPAPPADLAPPAPADVA
MLBr_02151|M.leprae_Br4923 PLAPPP--------------------------------------------
MAV_0996|M.avium_104 PQAPPADAPPPA--------------------------------------
MAB_0869c|M.abscessus_ATCC_199 APEPPAEGDEQFVA------------------------------------
TH_0358|M.thermoresistible__bu STPTATTGCGAIR-------------------------------------
. .
Mflv_1703|M.gilvum_PYR-GCK --------------------------------PPAPAPFDALAAPAPAPL
Mvan_5049|M.vanbaalenii_PYR-1 ----------------------------------APAPVDALAAPAP--L
MSMEG_5700|M.smegmatis_MC2_155 -----------------------------------PAPEG--LPPAPEAL
MUL_0283|M.ulcerans_Agy99 -----------------------------------PVELAANDVPAPADL
MMAR_4665|M.marinum_M -----------------------------------PVELAANDVPAPADL
Mb0891c|M.bovis_AF2122/97 -----------------------------------PADLAP---PAPADL
Rv0867c|M.tuberculosis_H37Rv PPVELAVNDLPAPLGEPLPAAPADPAPPADLAPPAPADLAP---PAPADL
MLBr_02151|M.leprae_Br4923 -----------------------------------PAEPAP---------
MAV_0996|M.avium_104 -----------------------------------PVQLASFDRPAPPDA
MAB_0869c|M.abscessus_ATCC_199 ---------------------------------EAPEAPAIDEAPAPEEA
TH_0358|M.thermoresistible__bu -----------------------------------PGAVLG---------
*
Mflv_1703|M.gilvum_PYR-GCK PPAPETLPPAPVEQLAAPVPLPAPAPEAVPVDAMA-APAPLPPAPEALPP
Mvan_5049|M.vanbaalenii_PYR-1 PPAPEALP-------------PAPAP-AAPFDAMS-APAPLPPAPEALP-
MSMEG_5700|M.smegmatis_MC2_155 PPAPEALP-------------PAPEAPAPAPEALPPAPEALPPAPEALPP
MUL_0283|M.ulcerans_Agy99 PP-APEDL--------------PP----APEDLAPPAPADLPPAPEDLPP
MMAR_4665|M.marinum_M PP-APEDL--------------PP----APEDLAPPAPADLPPAPEDLPP
Mb0891c|M.bovis_AF2122/97 APPAPADL--------------APPVELAVNDLPAPLGEPLPAAPAELAP
Rv0867c|M.tuberculosis_H37Rv APPAPADL--------------APPVELAVNDLPAPLGEPLPAAPAELAP
MLBr_02151|M.leprae_Br4923 ---------------------------------PQPPADNFPPTPGDVPS
MAV_0996|M.avium_104 P----------------------------APDAPPPAPADLPPAPADLPP
MAB_0869c|M.abscessus_ATCC_199 PAPEAQDVDFQSGPAPEE---PAPAPEPAPVDEAQAPAPELIAAPAPEAP
TH_0358|M.thermoresistible__bu -----------------------------LVDLRQVCAAFLTPLGVG---
: .
Mflv_1703|M.gilvum_PYR-GCK APLDAPAPAQTVAFDAVAAPA----PLP-APEALPPAPLPAPAPEAVP--
Mvan_5049|M.vanbaalenii_PYR-1 -----PAPAPAAPFDAMSAPA----PLPPAPEALP----PAPVVDAAN--
MSMEG_5700|M.smegmatis_MC2_155 AP-EAPAPAPEALPPAPEAPAPVAEALPPAPEALPPAPEAPPAPEALPPA
MUL_0283|M.ulcerans_Agy99 APQDLPPAPEDVAAPAPADLP-----------------------------
MMAR_4665|M.marinum_M APQDLPPAPEDVAAPAPADLPPAPEDVAPPVELVGNDVPAPVDLPPAP--
Mb0891c|M.bovis_AF2122/97 -PADLAPASADLAPPAPADLAP----------------------------
Rv0867c|M.tuberculosis_H37Rv -PADLAPASADLAPPAPADLAP----------------------------
MLBr_02151|M.leprae_Br4923 ----------PLARP-----------------------------------
MAV_0996|M.avium_104 ------APPADATPPAPPADAP----------------------------
MAB_0869c|M.abscessus_ATCC_199 VVDEAPAPEEAPAPEAPAADDQ----------------------------
TH_0358|M.thermoresistible__bu --------------------------------------------------
Mflv_1703|M.gilvum_PYR-GCK ----FDALSAPAPVEPIVAPIPVDAPP--SAVVTA---VNWDTAPAPAPG
Mvan_5049|M.vanbaalenii_PYR-1 ----IAPLDAPLP-----PPAPVDAPPAQSAIIAA---ANWDTAPVPG-E
MSMEG_5700|M.smegmatis_MC2_155 PEAQIVDASLQVPADVPPAPPVEPAPPAPVDAVAAPENQNWDQAPAPA-D
MUL_0283|M.ulcerans_Agy99 -------------------PAPADLPP-APEDLAP---------------
MMAR_4665|M.marinum_M -------EDLPPAPEDLAPPAPADLPP-APEDLAPPAPADLPPAPEDLAP
Mb0891c|M.bovis_AF2122/97 -------------------PAPAELAPPAPADLAPPAAVNEQTAPGDQPA
Rv0867c|M.tuberculosis_H37Rv -------------------PAPAELAPPAPADLAPPAAVNEQTAPGDQPA
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
MAV_0996|M.avium_104 -------------------APDGDFHGFVPAGMPD---------------
MAB_0869c|M.abscessus_ATCC_199 ----------VLPYELQSGPAPAEPAP-APEPAPAPAAAPEIPLPAGVPD
TH_0358|M.thermoresistible__bu --------------------------------------------------
Mflv_1703|M.gilvum_PYR-GCK DPQMWSLGLDAPLQPAPVTP-----PLPAPAP---ETVAAPAPVVGVPAG
Mvan_5049|M.vanbaalenii_PYR-1 HPQLWSLGVDAPLQPAPVLPP---APAPAPAP---AAVAAPAPDPLAPLG
MSMEG_5700|M.smegmatis_MC2_155 QPQTWALHVGGPLPLDPVLPAPAPAPAPAPAPGAPAAVAAPAPDPLAPAP
MUL_0283|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4665|M.marinum_M PAPADLPPAPEDLAPPAPADLPPAPEDLPPAP------------------
Mb0891c|M.bovis_AF2122/97 TAPGGPVGLATDLELPEPD----------PQP------------------
Rv0867c|M.tuberculosis_H37Rv TAPGGPVGLATDLELPEPD----------PQP------------------
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
MAV_0996|M.avium_104 --------------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 AADIGFAAGKAAFDAGPVASNGIPTSPEAVAG------------------
TH_0358|M.thermoresistible__bu --------------------------------------------------
Mflv_1703|M.gilvum_PYR-GCK QAG-PVPA-------------APAEVPHLVSPDNPPPGTTVTP-QGPQQS
Mvan_5049|M.vanbaalenii_PYR-1 AVEVPAPAYDIANQAISGELPVPSEVPHLASPDNLPPGTAMAP-QGPRQS
MSMEG_5700|M.smegmatis_MC2_155 NADVAPTP--------------PEGVPHLASPENLPPGTTETPDQIPGQG
MUL_0283|M.ulcerans_Agy99 -------------------------------------------PVDVHEA
MMAR_4665|M.marinum_M -------------------------------EDLPPPADADNPPVDVHEA
Mb0891c|M.bovis_AF2122/97 -------------------------------ADAPPPGDVTEAPAETPQV
Rv0867c|M.tuberculosis_H37Rv -------------------------------ADAPPPGDVTEAPAETPQV
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
MAV_0996|M.avium_104 ------------------------------------------------HV
MAB_0869c|M.abscessus_ATCC_199 ------------------------VVRHLPDPNNLPPG---TTDVAPGDS
TH_0358|M.thermoresistible__bu --------------------------------------------------
Mflv_1703|M.gilvum_PYR-GCK PNVTYLKEIWHAIQTQEISGSDALLALTQRPLTANG--GGPAP---MAPV
Mvan_5049|M.vanbaalenii_PYR-1 PNVTYLKEIWHAIQTQEISGADALLALTQRPLTTPDTPGGTPP---IAP-
MSMEG_5700|M.smegmatis_MC2_155 PNMTYLREIWHAIQTQDISGKDALLALTQRPLTTPDVPGGAAPNRPVAPP
MUL_0283|M.ulcerans_Agy99 STVAYTKKLWQAIVGQNISGNDALDALAQPAVFA----------------
MMAR_4665|M.marinum_M STVAYTKKLWQAIVGQNISGNDALDALAQPTVFA----------------
Mb0891c|M.bovis_AF2122/97 SNIAYTKKLWQAIRAQDVCGNDALDSLAQPYVIG----------------
Rv0867c|M.tuberculosis_H37Rv SNIAYTKKLWQAIRAQDVCGNDALDSLAQPYVIG----------------
MLBr_02151|M.leprae_Br4923 --------------------------------------------------
MAV_0996|M.avium_104 SEAGYTQRLWEAIRAQDVQGNDALDALVQPAPSA----------------
MAB_0869c|M.abscessus_ATCC_199 RGVSYLKDIVFAMQTQDVKASDAILALAQR--------------------
TH_0358|M.thermoresistible__bu --------------------------------------------------
Mflv_1703|M.gilvum_PYR-GCK ---GAPAPAPEAPVQGAAAPLPAPA-------VPAPAPVLPPA
Mvan_5049|M.vanbaalenii_PYR-1 ---GAPG-APVAPLAG-PAPAPAP--------VPAPAPVLPPA
MSMEG_5700|M.smegmatis_MC2_155 PAPGDPALAPAPAPLGAPAPAPAPEPAPVGAPAPVGAPVPPPA
MUL_0283|M.ulcerans_Agy99 -------------------------------------------
MMAR_4665|M.marinum_M -------------------------------------------
Mb0891c|M.bovis_AF2122/97 -------------------------------------------
Rv0867c|M.tuberculosis_H37Rv -------------------------------------------
MLBr_02151|M.leprae_Br4923 -------------------------------------------
MAV_0996|M.avium_104 -------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 -------------------------------------------
TH_0358|M.thermoresistible__bu -------------------------------------------