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MDPFLGTEALAAGSLTRYRLKTRFELVHRNVYALNREQLTPVQKARAAWLWSGRRGTLVGLSAAAVLGSR WIDARLPAELNQRSQHKTPGIVLRADTLGPDEIVTARGMPVTSPARTAFDLGRRRGLTLAVIRMDALMRT TGATTSDIATLLTRHKGARGLVQLRRALELVDPASESPQESRTRLLLVKAGLPPERSQIDVFDRDGYHVG RVDMGWETWKVGVEYEGEQHWTNPEQYAHDIDRQAALEAEGWRIIRVSAEILRDRPTTIVSRVWLALRAA GAPVQPPNLNL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5044 | - | - | 100% (291) | hypothetical protein Mvan_5044 |
| M. vanbaalenii PYR-1 | Mvan_1656 | - | 2e-52 | 41.03% (273) | hypothetical protein Mvan_1656 |
| M. vanbaalenii PYR-1 | Mvan_1630 | - | 1e-51 | 39.71% (277) | hypothetical protein Mvan_1630 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3585c | - | 2e-70 | 49.64% (280) | hypothetical protein Mb3585c |
| M. gilvum PYR-GCK | Mflv_4812 | - | 1e-55 | 41.79% (280) | hypothetical protein Mflv_4812 |
| M. tuberculosis H37Rv | Rv3555c | - | 2e-69 | 49.29% (280) | hypothetical protein Rv3555c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1200 | - | 1e-74 | 47.74% (287) | hypothetical protein MAB_1200 |
| M. marinum M | MMAR_4658 | - | 9e-77 | 52.36% (275) | hypothetical protein MMAR_4658 |
| M. avium 104 | MAV_1002 | - | 7e-85 | 58.27% (266) | hypothetical protein MAV_1002 |
| M. smegmatis MC2 155 | MSMEG_0914 | - | 1e-70 | 49.31% (288) | hypothetical protein MSMEG_0914 |
| M. thermoresistible (build 8) | TH_3487 | - | 1e-78 | 52.31% (281) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0276 | - | 1e-74 | 50.91% (275) | hypothetical protein MUL_0276 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3585c|M.bovis_AF2122/97 MDELPWPVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPAGVELTARQRAH
Rv3555c|M.tuberculosis_H37Rv MDELPWPVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPAGVELTARQRAH
MAB_1200|M.abscessus_ATCC_1997 MGDIPWPFRSTEMLSTGAVTEHYIRTRYRQLYPGICVPREVEVSATQRAY
MMAR_4658|M.marinum_M MEILDWPFRGTEALAAGAVTPHRLRTHFEMVHRNVYIPRGKKLTAVTRAI
MUL_0276|M.ulcerans_Agy99 MEILDWPFRGTEALAAGAVTPHRLRTHFEMVHRNVYIARGKKLTAVTRAI
MAV_1002|M.avium_104 -----------------------------MVHRNVYVRRGQQLTPVTRAV
Mvan_5044|M.vanbaalenii_PYR-1 ----MDPFLGTEALAAGSLTRYRLKTRFELVHRNVYALNREQLTPVQKAR
TH_3487|M.thermoresistible__bu --MAEGPFLGSEARAAGLVTRRTLRSRHRLIYQNVYLPVGVQLTAQTRAV
MSMEG_0914|M.smegmatis_MC2_155 ---MGDIIVGSEALSSGVLTRYALQTSYRKLHRNVYVPRDFSLDARSRAR
Mflv_4812|M.gilvum_PYR-GCK ---MGDIIIGTEAVANGTVTRHQLQRWYRPIFTNIHAPRGPAPTLGDRAV
:. .: :*
Mb3585c|M.bovis_AF2122/97 AAWLWSRRRAVVAGNSAAALLGAKWVNPALDAELVHANRKPPPRIVVHTD
Rv3555c|M.tuberculosis_H37Rv AAWLWSRRRAVVAGNSAAALLGAKWVNPALDAELVHANRKPPPRIVVHTD
MAB_1200|M.abscessus_ATCC_1997 SAWLWTGRRGVIAGLAASAVHGAKWVEAGVVVDLIHRHHKTARGLRIHRD
MMAR_4658|M.marinum_M AAWLWSGRSATAVGLSAAALHRTGWIDDWLPAELNRRGRDKARGIISHSA
MUL_0276|M.ulcerans_Agy99 AAWLWSGRSATAVGLSPAPLHRTGWIDDWLPAELNRRGRDKARDIISHSA
MAV_1002|M.avium_104 AAWLWSGRTATLAGLSAAALHRTAWIDDWLPAELNRAGRDKARGIILHSD
Mvan_5044|M.vanbaalenii_PYR-1 AAWLWSGRRGTLVGLSAAAVLGSRWIDARLPAELNQRSQHKTPGIVLRAD
TH_3487|M.thermoresistible__bu AAWLWARRDATVAGLSAAALHGTKWIDPALPAELIRPSPGSPDGIVIHRD
MSMEG_0914|M.smegmatis_MC2_155 AAWLWSGRTATLAGYSAAAMLGSRWLPDDAPAELARVRHPSPAGIRIHTG
Mflv_4812|M.gilvum_PYR-GCK GAWLYSKRHGIVTGLAAAALHGSRWIDADVDIELIYKCPRPPSGIVARND
.***:: * . .* :.:.: : *: :* . : :
Mb3585c|M.bovis_AF2122/97 RLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRLDALANSTDVKV
Rv3555c|M.tuberculosis_H37Rv RLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRLDALANSTDVKV
MAB_1200|M.abscessus_ATCC_1997 TLMDNEIDRIEGIAVTSPARTAFDVGRWLP-QAGAVERIDALMAATGLVT
MMAR_4658|M.marinum_M CLDEDEVCVRDGIALTTPARTAFDLGRRKG-LTTAVIRLDALTRATELKV
MUL_0276|M.ulcerans_Agy99 CLDEDEVCVRDGIALTTPARTAFDLGRRKG-LTTAVIRLDALTRATELKV
MAV_1002|M.avium_104 TLCDDETTMRDGMSLTTPARTAFDLGRRKG-LTTAVIRLDALMHASDVKT
Mvan_5044|M.vanbaalenii_PYR-1 TLGPDEIVTARGMPVTSPARTAFDLGRRRG-LTLAVIRMDALMRTTGATT
TH_3487|M.thermoresistible__bu RLEPGEVCTLRGIPVTTPARTAYDIGRRQT-LTRAVVRLDALANATGLTA
MSMEG_0914|M.smegmatis_MC2_155 VIADDEICRVGGMDCTTPARTAYDLGRRLP-VETGAIRLDALLNATKTDV
Mflv_4812|M.gilvum_PYR-GCK RIDPDEWQSIDGLPVATAARTAFDLGRYRP-EHDALARLDALMAVRPYSV
: * *: ::.****:*:** . *:*** .
Mb3585c|M.bovis_AF2122/97 ADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTRLVLIDAGLPKP
Rv3555c|M.tuberculosis_H37Rv ADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTRLVLIDAGLPKP
MAB_1200|M.abscessus_ATCC_1997 EQVEDVMKKHKGVRGLARLRSVLALVDGGSESPQETRTRLLLVKSGFPPP
MMAR_4658|M.marinum_M ADVEMLAERHRGARGLIQLRQALPLVDAGADSPYETRIRLLVIRSGLPAP
MUL_0276|M.ulcerans_Agy99 ADVEMLAERHRGARGLIQLRQALPLVDAGADSPYETRIRLLIIRSGLPAP
MAV_1002|M.avium_104 ADVELLADRHRGARGLVQLRRVLTLVDGGAESPYETKTRLLLAGSGLPRP
Mvan_5044|M.vanbaalenii_PYR-1 SDIATLLTRHKGARGLVQLRRALELVDPASESPQESRTRLLLVKAGLPPE
TH_3487|M.thermoresistible__bu DAVTAVIDRRRGARGLVRLRRAVGLMDGGAASPPETRTRLLLLAAGFPRP
MSMEG_0914|M.smegmatis_MC2_155 ADVMSVAERYRGARGIRRLRTTLDLVDPGAESPQETRLRLVLVRAGLPRP
Mflv_4812|M.gilvum_PYR-GCK EDVLLLTKRYKGARGVARLKALLPFVDGGAQSPRESWWRKLVLDSGFPPP
: : . *.**: :*: : ::* .: ** *: * :: :*:*
Mb3585c|M.bovis_AF2122/97 QTQIRVFDDYGDFVARIDLGYEQLRVGVEYDGPQHWTDPAQRARDIERST
Rv3555c|M.tuberculosis_H37Rv QTQIRVFDDYGDFVARIDLGYEQLRVGVEYDGPQHWTDPAQRARDIERST
MAB_1200|M.abscessus_ATCC_1997 QTQIRVFNRYGDFIARIDMGWEDLKVGVEFDGAQHWLDARQRSHDIDRAS
MMAR_4658|M.marinum_M QTEIKVLDDWGAVAARIGMGWPECKVGVEFDSAGQWNN-AARSDAVDRSA
MUL_0276|M.ulcerans_Agy99 QTEIKVLDDRGAVAARIGMGWPECKVGVEFDSAGQWNN-AARSDAFDRSA
MAV_1002|M.avium_104 QTQIEVRNEWGAVLARIDMGWEEWKVGVEFDGAQHWTDPAQRTRDIDRFA
Mvan_5044|M.vanbaalenii_PYR-1 RSQIDVFDRDGYHVGRVDMGWETWKVGVEYEGEQHWTNPEQYAHDIDRQA
TH_3487|M.thermoresistible__bu RTQVVVCDPFGYFIGRIDIGWPEYRVGVEYDGAWHWADAAAHAQTIDRVA
MSMEG_0914|M.smegmatis_MC2_155 VTQIPVLDERGRVRRRIDMGWPDRMVGAEYDGAHHWQDPAAHASDIDRLE
Mflv_4812|M.gilvum_PYR-GCK RTQIPVVDENGYHVRTLDFGWEGPNVAVEYDGDQHQSDRAQYLKDRRVMP
::: * : * :.:*: *..*::. : :
Mb3585c|M.bovis_AF2122/97 ALLDLGWTIIRVTSELLRYRRGTFVGRVDAAMRAAGWRP-----------
Rv3555c|M.tuberculosis_H37Rv ALLDLGWTIIRVTSELLWYRRGTFVGRVDAAMRAAGWRP-----------
MAB_1200|M.abscessus_ATCC_1997 ELAAQGWAIVRVSAEMLRHRAGTVVARVDAALRNAARPTTSASLTRISGQ
MMAR_4658|M.marinum_M ELEARGWTIVRVNAQTLKNRPDIVVAQVRHALVR-----RT---------
MUL_0276|M.ulcerans_Agy99 ELEARGWTIVRVNTQTLKNRPDIVVTQVRHALVR-----RT---------
MAV_1002|M.avium_104 ELEARGWTIVRVSADMLRYRPYDILSRTRNALRASGCPLRSPSVDLLGTT
Mvan_5044|M.vanbaalenii_PYR-1 ALEAEGWRIIRVSAEILRDRPTTIVSRVWLALRAAGAPVQPPNLNL----
TH_3487|M.thermoresistible__bu DLEEQGWIIIRISRDILRYRPGVFLARVRNALRAHGWP-DHASVRLDARL
MSMEG_0914|M.smegmatis_MC2_155 FLAAPGWTIIRVSHEHLRYRTPAVIARVRDALKCAEATVVRANS------
Mflv_4812|M.gilvum_PYR-GCK ALRRLGWHVTTVVKE---DDPVAVIQTLSAAMRARGWRGSIQIPRYAYTT
* ** : : : .: *:
Mb3585c|M.bovis_AF2122/97 -----------------------
Rv3555c|M.tuberculosis_H37Rv -----------------------
MAB_1200|M.abscessus_ATCC_1997 ISA--------------------
MMAR_4658|M.marinum_M -----------------------
MUL_0276|M.ulcerans_Agy99 -----------------------
MAV_1002|M.avium_104 QPISPNKSTFGGKGRPFGGKGRP
Mvan_5044|M.vanbaalenii_PYR-1 -----------------------
TH_3487|M.thermoresistible__bu EP---------------------
MSMEG_0914|M.smegmatis_MC2_155 -----------------------
Mflv_4812|M.gilvum_PYR-GCK RFRAEIASRQEKCE---------