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MGDIIIGTEAVANGTVTRHQLQRWYRPIFTNIHAPRGPAPTLGDRAVGAWLYSKRHGIVTGLAAAALHGS RWIDADVDIELIYKCPRPPSGIVARNDRIDPDEWQSIDGLPVATAARTAFDLGRYRPEHDALARLDALMA VRPYSVEDVLLLTKRYKGARGVARLKALLPFVDGGAQSPRESWWRKLVLDSGFPPPRTQIPVVDENGYHV RTLDFGWEGPNVAVEYDGDQHQSDRAQYLKDRRVMPALRRLGWHVTTVVKEDDPVAVIQTLSAAMRARGW RGSIQIPRYAYTTRFRAEIASRQEKCE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4812 | - | - | 100% (307) | hypothetical protein Mflv_4812 |
| M. gilvum PYR-GCK | Mflv_4733 | - | 4e-69 | 47.84% (278) | hypothetical protein Mflv_4733 |
| M. gilvum PYR-GCK | Mflv_1289 | - | 3e-67 | 47.67% (279) | hypothetical protein Mflv_1289 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3741c | - | 7e-87 | 54.45% (281) | hypothetical protein Mb3741c |
| M. tuberculosis H37Rv | Rv3714c | - | 7e-87 | 54.45% (281) | hypothetical protein Rv3714c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2184 | - | 3e-72 | 48.47% (295) | hypothetical protein MAB_2184 |
| M. marinum M | MMAR_0375 | - | 1e-73 | 48.75% (279) | hypothetical protein MMAR_0375 |
| M. avium 104 | MAV_0642 | - | 8e-66 | 45.23% (283) | hypothetical protein MAV_0642 |
| M. smegmatis MC2 155 | MSMEG_0256 | - | 8e-85 | 52.78% (288) | hypothetical protein MSMEG_0256 |
| M. thermoresistible (build 8) | TH_4125 | - | 2e-57 | 41.07% (280) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4737 | - | 1e-72 | 48.39% (279) | hypothetical protein MUL_4737 |
| M. vanbaalenii PYR-1 | Mvan_1630 | - | 1e-142 | 75.90% (307) | hypothetical protein Mvan_1630 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4812|M.gilvum_PYR-GCK ---------------MGDIIIGTEAVANGTVTRHQLQRWYRPIFTNIHAP
Mvan_1630|M.vanbaalenii_PYR-1 ---------------MGNIIIGTEAVATGVVTRHELQRWYRPIYRNVHAP
MSMEG_0256|M.smegmatis_MC2_155 ---------------MRQLIVGSQALAEGTVTEHELRRWYRRMYRDIYIP
Mb3741c|M.bovis_AF2122/97 MLISRMSVRSASMSVMGDVFIGSEAITAGRLTRHELQRWYQPMFRGVYVS
Rv3714c|M.tuberculosis_H37Rv MLISRMSVRSASMSVMGDVFIGSEAITAGRLTRHELQRWYQPMFRGVYVS
MMAR_0375|M.marinum_M -----MDAREARAARSEDVFVGSEAVRRGRLSPYRLRTEFRAIYPDVYLP
MUL_4737|M.ulcerans_Agy99 -----MDAREARAARSEDVFVGSGAVRRGRLSPYRLRTEFRAIYPDVYLP
MAB_2184|M.abscessus_ATCC_1997 ---------------MAAVFVGSEAVSAGQLTRHELQRFYRPIFRGVYLP
TH_4125|M.thermoresistible__bu ---------------MREVFIGSAALRGGGLTRGRLRWNYRAMYPDVYVA
MAV_0642|M.avium_104 ---------------MAEPFIGSEAVASGLVTPYALRSRFVRVHPDVYVP
::*: *: * :: *: : :. .:: .
Mflv_4812|M.gilvum_PYR-GCK RGPAPTLGDRAVGAWLYSKRHGIVTGLAAAALHGSRWIDADVDIELIYKC
Mvan_1630|M.vanbaalenii_PYR-1 KVPAPTLRDRAEGAWLYSQRAGILTGLAAAALHGSAWIDDDIDVELIYKC
MSMEG_0256|M.smegmatis_MC2_155 AGYTPTLIDHIDGAWLRSGRQGIVAGVAASALFGADWVDAGIAVEMVWDN
Mb3741c|M.bovis_AF2122/97 RRSVPTLWDRTVGAWLATRRHGVIAGNAASALHGAQWVDVDVAIELISPT
Rv3714c|M.tuberculosis_H37Rv RRSVPTLWDRTVGAWLATRRHGVIAGNAASALHGAQWVDVDVAIELISPT
MMAR_0375|M.marinum_M AHAAPSFRTRCKAAWLWTGRRGVLAGLAAAGLHGSDWIGDDEPVELIWRN
MUL_4737|M.ulcerans_Agy99 AHAAPSFRTRCKAAWLWTGRRGVLGGLAAAGLHGSDWIGDDEPVELIWRN
MAB_2184|M.abscessus_ATCC_1997 KSAEPTLRDRTVAAWLASGRRGVVAGLAASNLHGASWVDHDVPIELVGVK
TH_4125|M.thermoresistible__bu KDRPPTLRQFIVGAWLWSGREGVITGRAAAALHGAKYVDDATPIELIWKA
MAV_0642|M.avium_104 AGTALSAGLRARSAWLWSRRRGVVAGRSAAALYGTKWIDDRAPAQLLYPY
: .*** : * *:: * :*: *.*: ::. :::
Mflv_4812|M.gilvum_PYR-GCK PRPPSGIVARNDRIDPDEWQSIDGLPVATAARTAFDLGRYRPEHDALARL
Mvan_1630|M.vanbaalenii_PYR-1 PRPPTGIIARNERIAPDEWQALSGIPVTTPTRTAYDLGRFRPDHEALGRL
MSMEG_0256|M.smegmatis_MC2_155 TRPPRGIIARDERTEDDEITTAQCITVTTPARTAFDLGRHLRRSEALARM
Mb3741c|M.bovis_AF2122/97 TRPQHGLVIRRETLCDDEITRVVGLPVTTLARTAYDLGRHLSRGEAVARL
Rv3714c|M.tuberculosis_H37Rv TRPQHGLVIRRETLCDDEITRVVGLPVTTLARTAYDLGRHLSRGEAVARL
MMAR_0375|M.marinum_M PHPPAGVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVARL
MUL_4737|M.ulcerans_Agy99 PHPPAGVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVARL
MAB_2184|M.abscessus_ATCC_1997 CRQQEGLIARNERIGADEITRISGLPVTHRVRTAFDLGRYQPRTRAMGCL
TH_4125|M.thermoresistible__bu GRPPPRIIVRNERLDAADVTTVDDMLVTTPARTAFDLARHLPRDAAVRHL
MAV_0642|M.avium_104 RRPPDGIQTWSDRLVGDEIQTIGGMPVTTPARTALDIACRSPVDKAVAAI
: : : : : *: .*** *:. :: :
Mflv_4812|M.gilvum_PYR-GCK DALMAVRPYSVEDVLLLTKRYKGARGVARLKALLPFVDGGAQSPRESWWR
Mvan_1630|M.vanbaalenii_PYR-1 DALMRARPYSIDDVTALTLRYKGARGVARLKALLPYIDGGAESPRESWWR
MSMEG_0256|M.smegmatis_MC2_155 DALMRATAFSPDDVAALAERYRGARGIRQLRELLPLVDGGAESPRETRTR
Mb3741c|M.bovis_AF2122/97 DALMRATPFSRDDVLLLAKRHAGARGVRRLRDVLPLVDGGAASPKETWLR
Rv3714c|M.tuberculosis_H37Rv DALMRATPFSRDDVLLLAKRHAGARGVRRLRDVLPLVDGGAASPKETWLR
MMAR_0375|M.marinum_M DALMRATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRETWLR
MUL_4737|M.ulcerans_Agy99 DALMRATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRESWLR
MAB_2184|M.abscessus_ATCC_1997 DALMRNQVFALDEVAGLSQRYPKVRGVRQLRELLPLIDAGAQSPRESLIR
TH_4125|M.thermoresistible__bu DALAGATGVCAADVLPLADRYRRARGLPRARVALDLMDGGAQSPRETRLR
MAV_0642|M.avium_104 DALARATELKVLEIELLADRYRGRRGITRARNVLPLVDAGAESPRETWLR
*** :: *: *: **: : : * :*.** **:*: *
Mflv_4812|M.gilvum_PYR-GCK KLVLDSGFPPPRTQIPVVDENGYHVRTLDFGWEGPNVAVEYDGDQHQSDR
Mvan_1630|M.vanbaalenii_PYR-1 KLVIDSGFPTPATQIQVVDENGAHVRFVDFGWPDFLVAFEYDGDHHQSSR
MSMEG_0256|M.smegmatis_MC2_155 LLLFDAGFPRPTTQIPAVDERGRLVRMLDMGWEEFMVAAEYDGDQHRTER
Mb3741c|M.bovis_AF2122/97 LLLIDAGLPVPTTQIPVVHR-WRNVGVLDMGWEKYMVAAEYDGDQHRSDR
Rv3714c|M.tuberculosis_H37Rv LLLIDAGLPVPTTQIPVVHR-WRNVGVLDMGWEKYMVAAEYDGDQHRSDR
MMAR_0375|M.marinum_M MVLIDAGLPVPVTQIPVHQN-WRLVAVLDMGWQKYQVAAEYDGDQHRFDR
MUL_4737|M.ulcerans_Agy99 MVLIDAGLPVPVTQIPVHQN-WRLVAVLDMGWQKYQVAAEYDGDQHRFDR
MAB_2184|M.abscessus_ATCC_1997 LQLRDAGLPRAQTQVPVFDG-YTPIAFLDIGWPQYLVAVEYDGDHHRRDR
TH_4125|M.thermoresistible__bu LILVDDGLPRPRTQIGVSDG--VNEAFIDMGWDEPMVGLDYEGAHHSADR
MAV_0642|M.avium_104 LLLLRAGFPRPRTQLPVRQY-GALIACLDMGWEDIKLAVEYDGDQHRTDR
: *:* . **: . . :*:** :. :*:* :* .*
Mflv_4812|M.gilvum_PYR-GCK AQYLKDRRVMPALRRLGWHVTTVVKEDDPVAVIQTLSAAMRARGWRGSIQ
Mvan_1630|M.vanbaalenii_PYR-1 AQYLKDRRVLPELRRLNWHVTAVVKEDDPVLVINRLNAAMRARGWRGTVQ
MSMEG_0256|M.smegmatis_MC2_155 ARYVKDIRVWPKLRELGWDVIRVIKEDRDSDVLQRVHRALVARGWDGKLL
Mb3741c|M.bovis_AF2122/97 GRYVKDQRRLRKLAELGWIVIRVIAEDNPDDVVNRVRAALLARG------
Rv3714c|M.tuberculosis_H37Rv GRYVKDQRRLRKLAELGWIVIRVIAEDNPDDVVNRVRAALLARG------
MMAR_0375|M.marinum_M RQYARDQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALARRG------
MUL_4737|M.ulcerans_Agy99 RQYAREQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALARRG------
MAB_2184|M.abscessus_ATCC_1997 RQYVKDLARLRMLEERGWTVIRVIAEESPGAWIARTTAALRSRGCH----
TH_4125|M.thermoresistible__bu RQYVHDIGRAELIVGQGWLDIRVVAEHSRRFILHRTREAFARRG------
MAV_0642|M.avium_104 RQFTKDIRRAEVLAELGWTVVRVTAEDTPAGIIARVPTAWTRRACT----
:: :: : .* * . : * *.
Mflv_4812|M.gilvum_PYR-GCK IPRYAYTTRFRAEIASRQEKCE
Mvan_1630|M.vanbaalenii_PYR-1 IPSYAYAARHRAEIAARQEKFE
MSMEG_0256|M.smegmatis_MC2_155 P-------RLRSLQDRRISRPT
Mb3741c|M.bovis_AF2122/97 ---------WRP----------
Rv3714c|M.tuberculosis_H37Rv ---------WRP----------
MMAR_0375|M.marinum_M ---------HRET---------
MUL_4737|M.ulcerans_Agy99 ---------HRET---------
MAB_2184|M.abscessus_ATCC_1997 ---IEIDEMQRSTRPFAA----
TH_4125|M.thermoresistible__bu ---------WHLPKPV------
MAV_0642|M.avium_104 ----------GSEKPARNSR--