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GNIIIGTEAVATGVVTRHELQRWYRPIYRNVHAPKVPAPTLRDRAEGAWLYSQRAGILTGLAAAALHGSA WIDDDIDVELIYKCPRPPTGIIARNERIAPDEWQALSGIPVTTPTRTAYDLGRFRPDHEALGRLDALMRA RPYSIDDVTALTLRYKGARGVARLKALLPYIDGGAESPRESWWRKLVIDSGFPTPATQIQVVDENGAHVR FVDFGWPDFLVAFEYDGDHHQSSRAQYLKDRRVLPELRRLNWHVTAVVKEDDPVLVINRLNAAMRARGWR GTVQIPSYAYAARHRAEIAARQEKFE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1630 | - | - | 100% (307) | hypothetical protein Mvan_1630 |
| M. vanbaalenii PYR-1 | Mvan_5526 | - | 3e-75 | 53.02% (281) | hypothetical protein Mvan_5526 |
| M. vanbaalenii PYR-1 | Mvan_1730 | - | 5e-62 | 43.88% (278) | hypothetical protein Mvan_1730 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3741c | - | 3e-82 | 51.96% (281) | hypothetical protein Mb3741c |
| M. gilvum PYR-GCK | Mflv_4812 | - | 1e-142 | 75.90% (307) | hypothetical protein Mflv_4812 |
| M. tuberculosis H37Rv | Rv3714c | - | 3e-82 | 51.96% (281) | hypothetical protein Rv3714c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2184 | - | 1e-75 | 50.18% (279) | hypothetical protein MAB_2184 |
| M. marinum M | MMAR_0375 | - | 1e-71 | 48.40% (281) | hypothetical protein MMAR_0375 |
| M. avium 104 | MAV_4752 | - | 9e-67 | 44.00% (275) | hypothetical protein MAV_4752 |
| M. smegmatis MC2 155 | MSMEG_0256 | - | 6e-85 | 54.26% (282) | hypothetical protein MSMEG_0256 |
| M. thermoresistible (build 8) | TH_4125 | - | 2e-55 | 41.43% (280) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4737 | - | 9e-71 | 48.04% (281) | hypothetical protein MUL_4737 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4752|M.avium_104 --------------MGEAPVVGSEELASGRLNRHRLRVAYRPVFPNVYLP
TH_4125|M.thermoresistible__bu --------------MREV-FIGSAALRGGGLTRGRLRWNYRAMYPDVYVA
MAB_2184|M.abscessus_ATCC_1997 --------------MAAV-FVGSEAVSAGQLTRHELQRFYRPIFRGVYLP
Mb3741c|M.bovis_AF2122/97 MLISRMSVRSASMSVMGDVFIGSEAITAGRLTRHELQRWYQPMFRGVYVS
Rv3714c|M.tuberculosis_H37Rv MLISRMSVRSASMSVMGDVFIGSEAITAGRLTRHELQRWYQPMFRGVYVS
MMAR_0375|M.marinum_M -----MDAREARAARSEDVFVGSEAVRRGRLSPYRLRTEFRAIYPDVYLP
MUL_4737|M.ulcerans_Agy99 -----MDAREARAARSEDVFVGSGAVRRGRLSPYRLRTEFRAIYPDVYLP
Mvan_1630|M.vanbaalenii_PYR-1 ---------------MGNIIIGTEAVATGVVTRHELQRWYRPIYRNVHAP
Mflv_4812|M.gilvum_PYR-GCK ---------------MGDIIIGTEAVANGTVTRHQLQRWYRPIFTNIHAP
MSMEG_0256|M.smegmatis_MC2_155 ---------------MRQLIVGSQALAEGTVTEHELRRWYRRMYRDIYIP
.:*: : * :. .*: :: :: .:: .
MAV_4752|M.avium_104 AQVEPTLPLRIRAAWLWSGRTAVIAGAAAAAVHGAAWIPDAVPIELIHHN
TH_4125|M.thermoresistible__bu KDRPPTLRQFIVGAWLWSGREGVITGRAAAALHGAKYVDDATPIELIWKA
MAB_2184|M.abscessus_ATCC_1997 KSAEPTLRDRTVAAWLASGRRGVVAGLAASNLHGASWVDHDVPIELVGVK
Mb3741c|M.bovis_AF2122/97 RRSVPTLWDRTVGAWLATRRHGVIAGNAASALHGAQWVDVDVAIELISPT
Rv3714c|M.tuberculosis_H37Rv RRSVPTLWDRTVGAWLATRRHGVIAGNAASALHGAQWVDVDVAIELISPT
MMAR_0375|M.marinum_M AHAAPSFRTRCKAAWLWTGRRGVLAGLAAAGLHGSDWIGDDEPVELIWRN
MUL_4737|M.ulcerans_Agy99 AHAAPSFRTRCKAAWLWTGRRGVLGGLAAAGLHGSDWIGDDEPVELIWRN
Mvan_1630|M.vanbaalenii_PYR-1 KVPAPTLRDRAEGAWLYSQRAGILTGLAAAALHGSAWIDDDIDVELIYKC
Mflv_4812|M.gilvum_PYR-GCK RGPAPTLGDRAVGAWLYSKRHGIVTGLAAAALHGSRWIDADVDIELIYKC
MSMEG_0256|M.smegmatis_MC2_155 AGYTPTLIDHIDGAWLRSGRQGIVAGVAASALFGADWVDAGIAVEMVWDN
*:: .*** : * .:: * **: :.*: :: :*::
MAV_4752|M.avium_104 TRAPDGVLIRRDGLCPGETQICDGLAVTTPERTAFDIGRRGAVRSAVVRL
TH_4125|M.thermoresistible__bu GRPPPRIIVRNERLDAADVTTVDDMLVTTPARTAFDLARHLPRDAAVRHL
MAB_2184|M.abscessus_ATCC_1997 CRQQEGLIARNERIGADEITRISGLPVTHRVRTAFDLGRYQPRTRAMGCL
Mb3741c|M.bovis_AF2122/97 TRPQHGLVIRRETLCDDEITRVVGLPVTTLARTAYDLGRHLSRGEAVARL
Rv3714c|M.tuberculosis_H37Rv TRPQHGLVIRRETLCDDEITRVVGLPVTTLARTAYDLGRHLSRGEAVARL
MMAR_0375|M.marinum_M PHPPAGVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVARL
MUL_4737|M.ulcerans_Agy99 PHPPAGVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVARL
Mvan_1630|M.vanbaalenii_PYR-1 PRPPTGIIARNERIAPDEWQALSGIPVTTPTRTAYDLGRFRPDHEALGRL
Mflv_4812|M.gilvum_PYR-GCK PRPPSGIVARNDRIDPDEWQSIDGLPVATAARTAFDLGRYRPEHDALARL
MSMEG_0256|M.smegmatis_MC2_155 TRPPRGIIARDERTEDDEITTAQCITVTTPARTAFDLGRHLRRSEALARM
: :: * : : : *: ***:*:.* :: :
MAV_4752|M.avium_104 DSLARATGFKADDVLRVAGAHPRSPGLRRLEAALGLVDPGAQSPRESYLR
TH_4125|M.thermoresistible__bu DALAGATGVCAADVLPLADRYRRARGLPRARVALDLMDGGAQSPRETRLR
MAB_2184|M.abscessus_ATCC_1997 DALMRNQVFALDEVAGLSQRYPKVRGVRQLRELLPLIDAGAQSPRESLIR
Mb3741c|M.bovis_AF2122/97 DALMRATPFSRDDVLLLAKRHAGARGVRRLRDVLPLVDGGAASPKETWLR
Rv3714c|M.tuberculosis_H37Rv DALMRATPFSRDDVLLLAKRHAGARGVRRLRDVLPLVDGGAASPKETWLR
MMAR_0375|M.marinum_M DALMRATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRETWLR
MUL_4737|M.ulcerans_Agy99 DALMRATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRESWLR
Mvan_1630|M.vanbaalenii_PYR-1 DALMRARPYSIDDVTALTLRYKGARGVARLKALLPYIDGGAESPRESWWR
Mflv_4812|M.gilvum_PYR-GCK DALMAVRPYSVEDVLLLTKRYKGARGVARLKALLPFVDGGAQSPRESWWR
MSMEG_0256|M.smegmatis_MC2_155 DALMRATAFSPDDVAALAERYRGARGIRQLRELLPLVDGGAESPRETRTR
*:* :* :: : *: : . * :* ** **:*: *
MAV_4752|M.avium_104 LLLIDAGLPRPQTQVPVPGADGLPVAYLDMGWPEWMVAVEYDGDHHRTDR
TH_4125|M.thermoresistible__bu LILVDDGLPRPRTQIGVS--DGVNEAFIDMGWDEPMVGLDYEGAHHSADR
MAB_2184|M.abscessus_ATCC_1997 LQLRDAGLPRAQTQVPVFD-GYTPIAFLDIGWPQYLVAVEYDGDHHRRDR
Mb3741c|M.bovis_AF2122/97 LLLIDAGLPVPTTQIPVVH-RWRNVGVLDMGWEKYMVAAEYDGDQHRSDR
Rv3714c|M.tuberculosis_H37Rv LLLIDAGLPVPTTQIPVVH-RWRNVGVLDMGWEKYMVAAEYDGDQHRSDR
MMAR_0375|M.marinum_M MVLIDAGLPVPVTQIPVHQ-NWRLVAVLDMGWQKYQVAAEYDGDQHRFDR
MUL_4737|M.ulcerans_Agy99 MVLIDAGLPVPVTQIPVHQ-NWRLVAVLDMGWQKYQVAAEYDGDQHRFDR
Mvan_1630|M.vanbaalenii_PYR-1 KLVIDSGFPTPATQIQVVDENGAHVRFVDFGWPDFLVAFEYDGDHHQSSR
Mflv_4812|M.gilvum_PYR-GCK KLVLDSGFPPPRTQIPVVDENGYHVRTLDFGWEGPNVAVEYDGDQHQSDR
MSMEG_0256|M.smegmatis_MC2_155 LLLFDAGFPRPTTQIPAVDERGRLVRMLDMGWEEFMVAAEYDGDQHRTER
: * *:* . **: . :*:** *. :*:* :* .*
MAV_4752|M.avium_104 RQYVKDIRRLEMLEQLGWVIVRVVAEDRPADIVRRVRAALAKSGVAPRLS
TH_4125|M.thermoresistible__bu RQYVHDIGRAELIVGQGWLDIRVVAEHSRRFILHRTREAFARRGWHLPKP
MAB_2184|M.abscessus_ATCC_1997 RQYVKDLARLRMLEERGWTVIRVIAEESPGAWIARTTAALRSRGCHIEID
Mb3741c|M.bovis_AF2122/97 GRYVKDQRRLRKLAELGWIVIRVIAEDNPDDVVNRVRAALLARGWRP---
Rv3714c|M.tuberculosis_H37Rv GRYVKDQRRLRKLAELGWIVIRVIAEDNPDDVVNRVRAALLARGWRP---
MMAR_0375|M.marinum_M RQYARDQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALARRGHRET--
MUL_4737|M.ulcerans_Agy99 RQYAREQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALARRGHRET--
Mvan_1630|M.vanbaalenii_PYR-1 AQYLKDRRVLPELRRLNWHVTAVVKEDDPVLVINRLNAAMRARGWRGTVQ
Mflv_4812|M.gilvum_PYR-GCK AQYLKDRRVMPALRRLGWHVTTVVKEDDPVAVIQTLSAAMRARGWRGSIQ
MSMEG_0256|M.smegmatis_MC2_155 ARYVKDIRVWPKLRELGWDVIRVIKEDRDSDVLQRVHRALVARGWDGKLL
:* :: : .* *: . : *: *
MAV_4752|M.avium_104 V---------------------
TH_4125|M.thermoresistible__bu V---------------------
MAB_2184|M.abscessus_ATCC_1997 EMQRSTRPFAA-----------
Mb3741c|M.bovis_AF2122/97 ----------------------
Rv3714c|M.tuberculosis_H37Rv ----------------------
MMAR_0375|M.marinum_M ----------------------
MUL_4737|M.ulcerans_Agy99 ----------------------
Mvan_1630|M.vanbaalenii_PYR-1 IPSYAYAARHRAEIAARQEKFE
Mflv_4812|M.gilvum_PYR-GCK IPRYAYTTRFRAEIASRQEKCE
MSMEG_0256|M.smegmatis_MC2_155 P-------RLRSLQDRRISRPT