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DELPWPVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPAGVELTARQRAHAAWLWSRRRAVVAGNSAAALL GAKWVNPALDAELVHANRKPPPRIVVHTDRLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRLDA LANSTDVKVADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTRLVLIDAGLPKPQTQIRVFDDYG DFVARIDLGYEQLRVGVEYDGPQHWTDPAQRARDIERSTALLDLGWTIIRVTSELLWYRRGTFVGRVDAA MRAAGWRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3555c | - | - | 100% (289) | hypothetical protein Rv3555c |
| M. tuberculosis H37Rv | Rv3517 | - | 5e-71 | 49.45% (275) | hypothetical protein Rv3517 |
| M. tuberculosis H37Rv | Rv1482c | - | 5e-60 | 45.77% (260) | hypothetical protein Rv1482c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3585c | - | 1e-166 | 99.65% (289) | hypothetical protein Mb3585c |
| M. gilvum PYR-GCK | Mflv_4812 | - | 4e-59 | 41.28% (281) | hypothetical protein Mflv_4812 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1200 | - | 2e-83 | 50.88% (285) | hypothetical protein MAB_1200 |
| M. marinum M | MMAR_4658 | - | 2e-63 | 46.81% (282) | hypothetical protein MMAR_4658 |
| M. avium 104 | MAV_3234 | - | 2e-79 | 55.76% (278) | hypothetical protein MAV_3234 |
| M. smegmatis MC2 155 | MSMEG_5314 | - | 8e-79 | 51.39% (288) | hypothetical protein MSMEG_5314 |
| M. thermoresistible (build 8) | TH_3487 | - | 1e-79 | 53.74% (281) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2811 | - | 3e-61 | 47.16% (282) | hypothetical protein MUL_2811 |
| M. vanbaalenii PYR-1 | Mvan_5044 | - | 3e-69 | 49.29% (280) | hypothetical protein Mvan_5044 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3555c|M.tuberculosis_H37Rv -------MDELPWPVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPAGVEL
Mb3585c|M.bovis_AF2122/97 -------MDELPWPVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPAGVEL
MAB_1200|M.abscessus_ATCC_1997 -------MGDIPWPFRSTEMLSTGAVTEHYIRTRYRQLYPGICVPREVEV
MSMEG_5314|M.smegmatis_MC2_155 MGCDRPGMQTIDWPFRAVEALEAGALTFRELRRFHTAVYPGVWVPREAEL
MMAR_4658|M.marinum_M -------MEILDWPFRGTEALAAGAVTPHRLRTHFEMVHRNVYIPRGKKL
TH_3487|M.thermoresistible__bu ---------MAEGPFLGSEARAAGLVTRRTLRSRHRLIYQNVYLPVGVQL
MAV_3234|M.avium_104 ---------------MGTEALSAGALTERDLRRSCTRIYRNVYQRG-ADF
Mvan_5044|M.vanbaalenii_PYR-1 -----------MDPFLGTEALAAGSLTRYRLKTRFELVHRNVYALNREQL
Mflv_4812|M.gilvum_PYR-GCK -------MGDI---IIGTEAVANGTVTRHQLQRWYRPIFTNIHAPRGPAP
MUL_2811|M.ulcerans_Agy99 -------MCDLRAPFIGSKALACGAVTRHQLRTRYRPVLPNVYLSAGVHP
. : :. :: : .:
Rv3555c|M.tuberculosis_H37Rv TARQRAHAAWLWSRRRAVVAGNSAAALLGAKWVNPALDAELVHANRKPPP
Mb3585c|M.bovis_AF2122/97 TARQRAHAAWLWSRRRAVVAGNSAAALLGAKWVNPALDAELVHANRKPPP
MAB_1200|M.abscessus_ATCC_1997 SATQRAYSAWLWTGRRGVIAGLAASAVHGAKWVEAGVVVDLIHRHHKTAR
MSMEG_5314|M.smegmatis_MC2_155 SPVQRARAAWLWSGRAGVPAGLSASAMLGSKWIDQRDPAELIHTNRRPPR
MMAR_4658|M.marinum_M TAVTRAIAAWLWSGRSATAVGLSAAALHRTGWIDDWLPAELNRRGRDKAR
TH_3487|M.thermoresistible__bu TAQTRAVAAWLWARRDATVAGLSAAALHGTKWIDPALPAELIRPSPGSPD
MAV_3234|M.avium_104 TASDRAIAAWLWSGRRAVVAGNSAAALLGAQWVDPRAPAELITDRKRPPP
Mvan_5044|M.vanbaalenii_PYR-1 TPVQKARAAWLWSGRRGTLVGLSAAAVLGSRWIDARLPAELNQRSQHKTP
Mflv_4812|M.gilvum_PYR-GCK TLGDRAVGAWLYSKRHGIVTGLAAAALHGSRWIDADVDIELIYKCPRPPS
MUL_2811|M.ulcerans_Agy99 CLQSRIAAAWLWSRGSATVGGAAAAALHGAKWIPEDVPVELICARSSPPR
: .***:: . * :*:*: : *: :* .
Rv3555c|M.tuberculosis_H37Rv RIVVHTDRLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRLDALA
Mb3585c|M.bovis_AF2122/97 RIVVHTDRLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRLDALA
MAB_1200|M.abscessus_ATCC_1997 GLRIHRDTLMDNEIDRIEGIAVTSPARTAFDVGRWLP-QAGAVERIDALM
MSMEG_5314|M.smegmatis_MC2_155 LLTVHSDTLSDGETQVIDGMVVTTPARTAFDLGRRLP-FVDGVQRIDALM
MMAR_4658|M.marinum_M GIISHSACLDEDEVCVRDGIALTTPARTAFDLGRRKG-LTTAVIRLDALT
TH_3487|M.thermoresistible__bu GIVIHRDRLEPGEVCTLRGIPVTTPARTAYDIGRRQT-LTRAVVRLDALA
MAV_3234|M.avium_104 LIVARNETLLPDEITEVRGVPVTTPARTAYDLGRRPG-LVAAVIAIDSLA
Mvan_5044|M.vanbaalenii_PYR-1 GIVLRADTLGPDEIVTARGMPVTSPARTAFDLGRRRG-LTLAVIRMDALM
Mflv_4812|M.gilvum_PYR-GCK GIVARNDRIDPDEWQSIDGLPVATAARTAFDLGRYRP-EHDALARLDALM
MUL_2811|M.ulcerans_Agy99 GVLTRRDVLIDGETQFLGGYSVTTAERTAFDIGRRGA-MRSAVVRLDALA
: : : * * :::. ***:*:** .: :*:*
Rv3555c|M.tuberculosis_H37Rv NSTDVKVADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTRLVLI
Mb3585c|M.bovis_AF2122/97 NSTDVKVADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTRLVLI
MAB_1200|M.abscessus_ATCC_1997 AATGLVTEQVEDVMKKHKGVRGLARLRSVLALVDGGSESPQETRTRLLLV
MSMEG_5314|M.smegmatis_MC2_155 NATHVKVEEVLALAEGYRGARGVRRLRLILEYVDGGAESPYESSTRIMLV
MMAR_4658|M.marinum_M RATELKVADVEMLAERHRGARGLIQLRQALPLVDAGADSPYETRIRLLVI
TH_3487|M.thermoresistible__bu NATGLTADAVTAVIDRRRGARGLVRLRRAVGLMDGGAASPPETRTRLLLL
MAV_3234|M.avium_104 RATGLTTECVEPLMRAHRGARGVRQLRRVLPLIDAGAESPQETRTRLAIV
Mvan_5044|M.vanbaalenii_PYR-1 RTTGATTSDIATLLTRHKGARGLVQLRRALELVDPASESPQESRTRLLLV
Mflv_4812|M.gilvum_PYR-GCK AVRPYSVEDVLLLTKRYKGARGVARLKALLPFVDGGAQSPRESWWRKLVL
MUL_2811|M.ulcerans_Agy99 RATGFTVADVLQVARNHRGTRGLRQLETALELVDPGAQSPRESYLRLFLI
. : : *.**: :*. : :* .: ** *: * ::
Rv3555c|M.tuberculosis_H37Rv DAGLPKPQTQIRVFDDYGDFVARIDLGYEQLRVGVEYDGPQHWTDPAQRA
Mb3585c|M.bovis_AF2122/97 DAGLPKPQTQIRVFDDYGDFVARIDLGYEQLRVGVEYDGPQHWTDPAQRA
MAB_1200|M.abscessus_ATCC_1997 KSGFPPPQTQIRVFNRYGDFIARIDMGWEDLKVGVEFDGAQHWLDARQRS
MSMEG_5314|M.smegmatis_MC2_155 TNGFPEPETQIEVADASGTVFARLDMGWPEYRVAVEFDGAQHWTDSEQRS
MMAR_4658|M.marinum_M RSGLPAPQTEIKVLDDWGAVAARIGMGWPECKVGVEFDSAGQWNN-AARS
TH_3487|M.thermoresistible__bu AAGFPRPRTQVVVCDPFGYFIGRIDIGWPEYRVGVEYDGAWHWADAAAHA
MAV_3234|M.avium_104 GAGLPKPSTQITVHNDWGFVLARIDLGWEQWRVGVEYDGAQHWTDPRIRA
Mvan_5044|M.vanbaalenii_PYR-1 KAGLPPERSQIDVFDRDGYHVGRVDMGWETWKVGVEYEGEQHWTNPEQYA
Mflv_4812|M.gilvum_PYR-GCK DSGFPPPRTQIPVVDENGYHVRTLDFGWEGPNVAVEYDGDQHQSDRAQYL
MUL_2811|M.ulcerans_Agy99 DAGLPRPQTQLPVLGVNGMPVAYLDMGWERYMVAVEYDGDHHRSDRQQYV
*:* ::: * . * :.:*: *.**::. : :
Rv3555c|M.tuberculosis_H37Rv RDIERSTALLDLGWTIIRVTSELLWYRRGTFVGRVD----------AAMR
Mb3585c|M.bovis_AF2122/97 RDIERSTALLDLGWTIIRVTSELLRYRRGTFVGRVD----------AAMR
MAB_1200|M.abscessus_ATCC_1997 HDIDRASELAAQGWAIVRVSAEMLRHRAGTVVARVD----------AALR
MSMEG_5314|M.smegmatis_MC2_155 WDIDRQAMLEALGWTVIRVSAGLLHGRRQVVVDRVR----------AALL
MMAR_4658|M.marinum_M DAVDRSAELEARGWTIVRVNAQTLKNRPDIVVAQVR----------HALV
TH_3487|M.thermoresistible__bu QTIDRVADLEEQGWIIIRISRDILRYRPGVFLARVRNALRAHGWPDHASV
MAV_3234|M.avium_104 KDIDRVAELERRGWRIIRVSADLLRNRPDVLVGRIR----------EALC
Mvan_5044|M.vanbaalenii_PYR-1 HDIDRQAALEAEGWRIIRVSAEILRDRPTTIVSRVW----------LALR
Mflv_4812|M.gilvum_PYR-GCK KDRRVMPALRRLGWHVTTVVKE---DDPVAVIQTLS----------AAMR
MUL_2811|M.ulcerans_Agy99 KDIRRGEMLERMGWIVIRVVAE---DRRVDILRRVT----------AALA
* ** : : .: : *
Rv3555c|M.tuberculosis_H37Rv AAGWRP-------------------------
Mb3585c|M.bovis_AF2122/97 AAGWRP-------------------------
MAB_1200|M.abscessus_ATCC_1997 NAARPTTSASLTRISGQISA-----------
MSMEG_5314|M.smegmatis_MC2_155 ARGCRMGPGRAERAF----------------
MMAR_4658|M.marinum_M RRT----------------------------
TH_3487|M.thermoresistible__bu RLDARLEP-----------------------
MAV_3234|M.avium_104 AAGCPL-------------------------
Mvan_5044|M.vanbaalenii_PYR-1 AAGAPVQPPNLNL------------------
Mflv_4812|M.gilvum_PYR-GCK ARGWRGSIQIPRYAYTTRFRAEIASRQEKCE
MUL_2811|M.ulcerans_Agy99 ER--RSAVP----------------------